0:00:02 > 0:00:06What would a doctor discover if they lived with you 24 hours a day?
0:00:06 > 0:00:08- Hello.- Hello.
0:00:08 > 0:00:10Come and meet the doctor.
0:00:10 > 0:00:13How much would you be willing to reveal?
0:00:13 > 0:00:17I'm scared that I might get bullied for how I look and my weight.
0:00:17 > 0:00:19I feel like I'm drugged.
0:00:19 > 0:00:21But Nicola, you're right, you are drugged.
0:00:21 > 0:00:23Would they be shocked by what they find?
0:00:23 > 0:00:26Nobody has explained to her,
0:00:26 > 0:00:29in language that she understands,
0:00:29 > 0:00:31how to manage the condition.
0:00:31 > 0:00:32It's not acceptable.
0:00:33 > 0:00:36Most GPs only get about ten minutes with each patient.
0:00:36 > 0:00:41Dr Rangan Chatterjee wants to try a different approach.
0:00:41 > 0:00:43All the time in my consultation room,
0:00:43 > 0:00:46I'm seeing problems that are lifestyle problems.
0:00:46 > 0:00:49And they don't need a pill - they need a lifestyle change.
0:00:50 > 0:00:53He's about to spend time with families
0:00:53 > 0:00:55who struggle with their health.
0:00:55 > 0:00:57Everything they've tried has basically failed.
0:00:57 > 0:00:59PAINED GROANING
0:00:59 > 0:01:03He'll gain insight into every aspect of his patients' lives.
0:01:03 > 0:01:05How do they eat? How do they sleep?
0:01:05 > 0:01:09How do they move and exercise and how do they switch off and relax?
0:01:09 > 0:01:12He'll detect undiagnosed illnesses...
0:01:12 > 0:01:15It probably puts you at high risk of early death.
0:01:15 > 0:01:16..deliver some home truths...
0:01:16 > 0:01:19I think this fear is holding you back.
0:01:19 > 0:01:21Please don't turn it into this is...
0:01:21 > 0:01:24this is because I'm mentally fearful.
0:01:24 > 0:01:29..and discover ways we could all live longer, healthier lives.
0:01:29 > 0:01:33It's amazing how many times, when you get those basics right,
0:01:33 > 0:01:35all the other problems get so much better.
0:01:35 > 0:01:38Feeling good, energy up,
0:01:38 > 0:01:40I can even dance.
0:01:40 > 0:01:42- Can I have a dance with you? - LAUGHTER
0:01:48 > 0:01:49I forgot the poo bags.
0:01:49 > 0:01:52Right, come on, then, let's go, let's go.
0:01:54 > 0:01:58Tonight, Rangan will meet two families blighted by illness.
0:01:59 > 0:02:02The first are the Gleesons from Wirral near Liverpool -
0:02:02 > 0:02:05Dad, 35-year-old Trevor...
0:02:05 > 0:02:07There you go, grab him for me.
0:02:07 > 0:02:08..13-year-old Gina-Louise...
0:02:08 > 0:02:10No, don't chew your hair.
0:02:10 > 0:02:13I chew my hair. What's wrong with chewing your hair?
0:02:13 > 0:02:14Everything.
0:02:14 > 0:02:17..Marley, who is 12,
0:02:17 > 0:02:20and Mum, 34-year-old Emma.
0:02:20 > 0:02:22I would explain you as...
0:02:24 > 0:02:27- ..overprotective... - But really energetic.
0:02:27 > 0:02:29Energetic, but overprotective
0:02:29 > 0:02:32and it's, like, nice to see how much you love us,
0:02:32 > 0:02:34but sometimes, it's a bit like, you know...
0:02:34 > 0:02:36- Too much.- "Calm down."
0:02:36 > 0:02:40Yeah, well, you never know whether there's a kidnapper or paedophile. That's all I'm saying.
0:02:40 > 0:02:43Emma has been suffering from severe anxiety,
0:02:43 > 0:02:46panic attacks and depression since she was 19.
0:02:46 > 0:02:48It's escalated over the years.
0:02:48 > 0:02:52I can have three or four a day, so it varies.
0:02:52 > 0:02:55It just depends, and it's been quite hard to deal with.
0:02:55 > 0:02:58It affects our family life, what we can do as a family.
0:02:58 > 0:03:01The kids have seen them as well, which must be scary for them,
0:03:01 > 0:03:02if their mum's screaming in terror.
0:03:02 > 0:03:05No-one wants to see the strongest figure in their life
0:03:05 > 0:03:08sad or upset or see them...
0:03:08 > 0:03:10I don't want to say "weak", but...
0:03:10 > 0:03:12not in their usual state, really.
0:03:12 > 0:03:15She's trying to stop herself from having panic attacks every day now
0:03:15 > 0:03:17or a few times a day.
0:03:17 > 0:03:20I feel like I'm unfixable. I just feel like I'm a big mess.
0:03:20 > 0:03:23You'll be fine, come here, you'll be fine. Don't worry.
0:03:23 > 0:03:26- We'll be all right. OK. - SHE SOBS
0:03:28 > 0:03:30In the surgery, it can be really difficult
0:03:30 > 0:03:34managing patients with anxiety because you don't have much time
0:03:34 > 0:03:37and there are so many different causes.
0:03:37 > 0:03:39It's very, very hard to get to the bottom of it
0:03:39 > 0:03:41in just a few minutes.
0:03:42 > 0:03:45Emma has been battling anxiety for 15 years,
0:03:45 > 0:03:48but her symptoms are getting worse and she's now at breaking point.
0:03:50 > 0:03:52She's turned to Dr Rangan Chatterjee for help.
0:03:52 > 0:03:54He'll devote the next two months
0:03:54 > 0:03:56trying to get to the root of the problem.
0:03:56 > 0:03:58- Hi. - ALL: Hi.
0:03:58 > 0:04:01- How are you guys? Are you well? - Very well, yeah.- Yeah?
0:04:01 > 0:04:03Well, obviously not great, cos that's why you are here.
0:04:03 > 0:04:05- LAUGHTER - Yes, absolutely.
0:04:05 > 0:04:08We're going to have to...spend a bit of time together
0:04:08 > 0:04:11and really try and understand what's going on.
0:04:11 > 0:04:12So, yeah...
0:04:12 > 0:04:15- And try and fix us. - Try my best, I'll try my best.
0:04:15 > 0:04:18Certainly, the more information I can get, the more it helps me.
0:04:18 > 0:04:20Yeah.
0:04:21 > 0:04:23Can you tell me a little bit more about what happens
0:04:23 > 0:04:25when you have a panic attack?
0:04:25 > 0:04:28Just an immense fear of death.
0:04:28 > 0:04:30It's just an overwhelming, horrible fear,
0:04:30 > 0:04:32right in the pit of my stomach
0:04:32 > 0:04:36and I can either try and control it, and shake instead,
0:04:36 > 0:04:39or I can just end up screaming and screaming
0:04:39 > 0:04:41and screaming and screaming.
0:04:41 > 0:04:44So what happens in all of the panic attacks
0:04:44 > 0:04:46is that you have this fear that you're going to die?
0:04:46 > 0:04:49It's the thing. I can't go too far
0:04:49 > 0:04:51cos I don't want to start screaming in front of everyone
0:04:51 > 0:04:55but it's just that - "What happens after you die?"
0:04:55 > 0:04:57I wish I could just die for ten minutes so I could know,
0:04:57 > 0:04:59- and then come back.- Yeah.
0:04:59 > 0:05:02- And you already have. - I didn't die. I didn't die.
0:05:02 > 0:05:05She was in intensive care, in a coma, for a while,
0:05:05 > 0:05:07and that might have had something to do with it.
0:05:07 > 0:05:09That's got everything to do with it.
0:05:09 > 0:05:11So can you tell me a little bit about that?
0:05:11 > 0:05:13When I was 19, I had pneumonia,
0:05:13 > 0:05:15which instantly sent me into panic mode
0:05:15 > 0:05:18because my nan's husband had not long died from pneumonia.
0:05:18 > 0:05:22Then they had to take me into intensive care
0:05:22 > 0:05:25and I was out for about three-and-a-half, four weeks,
0:05:25 > 0:05:27and then I woke up with the tracheotomy thing in.
0:05:27 > 0:05:30It sounds really quite terrifying
0:05:30 > 0:05:33and likely to be hugely significant here.
0:05:33 > 0:05:37Anxiety is one of the most common mental health problems in the UK.
0:05:37 > 0:05:40It's thought that around one in 20 people
0:05:40 > 0:05:43are living with generalised anxiety.
0:05:43 > 0:05:48I've got the same thing, but they're in different bags.
0:05:48 > 0:05:51To help her cope, Emma takes antidepressants.
0:05:51 > 0:05:53The citalopram has definitely helped with my mood
0:05:53 > 0:05:56because before I had that, I was an absolute mess, wasn't I?
0:05:56 > 0:05:59One of your doctors has in the past referred you to a counsellor.
0:05:59 > 0:06:02- I've seen a few. - You've seen a few counsellors
0:06:02 > 0:06:03but you found they're not very useful.
0:06:03 > 0:06:06I've never seen it through. With this whole fear of death thing,
0:06:06 > 0:06:09I'm scared that I'll go to it and they'll say,
0:06:09 > 0:06:11"You'll have to face up to it, won't you?"
0:06:11 > 0:06:14I'm scared of someone saying that to me, so I've gone...
0:06:14 > 0:06:17Further to the fact that they give me the thing and say,
0:06:17 > 0:06:18"You make the appointment,"
0:06:18 > 0:06:20I'll tell you I'll make the appointment,
0:06:20 > 0:06:22but I'm not going to make the appointment.
0:06:23 > 0:06:25Rangan wants to find out how the rest of the family
0:06:25 > 0:06:28are affected by Emma's condition.
0:06:28 > 0:06:31- What are you guys up to? - We're just hanging out, really.
0:06:31 > 0:06:35What are the main things you would like me to help your mum with?
0:06:35 > 0:06:38Her panic attacks because it makes us a bit apprehensive
0:06:38 > 0:06:42when we are at school or, in my dad's instance, at work,
0:06:42 > 0:06:44cos we never know if she's 100% OK.
0:06:44 > 0:06:47She doesn't really know how to take her mind off it
0:06:47 > 0:06:49unless she is at home and she can tell us
0:06:49 > 0:06:53that she's not feeling great or she is close to having a panic attack.
0:06:53 > 0:06:54And you're able to...
0:06:54 > 0:06:57You're the only one there, but you know how to handle it.
0:06:57 > 0:07:00- Has that happened before?- When I was going to her work with her,
0:07:00 > 0:07:01it was on the bus then,
0:07:01 > 0:07:05she got a bit stressed and I just calmed her down.
0:07:05 > 0:07:07I got a few glances off people on the bus,
0:07:07 > 0:07:09but I didn't care, as long as she was OK.
0:07:12 > 0:07:16Understanding Emma's routine could give Rangan valuable information.
0:07:16 > 0:07:19How often do you come to the shop, normally?
0:07:19 > 0:07:21Um... Well, for beer, it'll be daily.
0:07:21 > 0:07:24- Daily? Every day?- Yeah. - Right, so they know you.
0:07:24 > 0:07:25Yeah, or I'd send Trev.
0:07:25 > 0:07:27How much do you drink?
0:07:27 > 0:07:30It depends what day it is. So, you have...
0:07:32 > 0:07:36Monday, Tuesday, will be two cans of beer.
0:07:36 > 0:07:40- Wednesday is normally a bottle of wine.- Yeah.
0:07:40 > 0:07:43Thursday, bottle of wine.
0:07:43 > 0:07:45Friday, two cans of beer, bottle of wine.
0:07:45 > 0:07:48Saturday, two cans of beer and a bottle of wine
0:07:48 > 0:07:52and Sunday, a few beers or a couple of glasses of wine.
0:07:53 > 0:07:56OK. That's quite a lot, isn't it?
0:07:56 > 0:07:57Yeah.
0:07:57 > 0:07:59I was trying to clock it up
0:07:59 > 0:08:03and it's not far off 60 to 70 units...a week
0:08:03 > 0:08:05and the government actually recommend,
0:08:05 > 0:08:07and the NHS recommend,
0:08:07 > 0:08:10that we don't drink more than 14 units per week.
0:08:10 > 0:08:13- Four to five times over, so... - Yeah.- It is a lot.
0:08:13 > 0:08:17- So, OK, you normally have Prosecco or Cava.- Yeah.
0:08:17 > 0:08:21Three lots of that, so 12 of those, five of these. Yeah. OK.
0:08:21 > 0:08:24You've got problems with anxiety, OK?
0:08:24 > 0:08:26And when you drink alcohol,
0:08:26 > 0:08:28alcohol increases the level of a chemical in our brains
0:08:28 > 0:08:32called GABA, and GABA actually dampens down things in the brain,
0:08:32 > 0:08:35slows down the way our brain cells talk to each other,
0:08:35 > 0:08:37so, actually, if you're feeling anxious
0:08:37 > 0:08:38and you have a glass of Prosecco,
0:08:38 > 0:08:41in the short term, it's going to make you feel better.
0:08:41 > 0:08:43The more you drink, the more alcohol you then need
0:08:43 > 0:08:45to have the same effects, because you become
0:08:45 > 0:08:48a little bit tolerant to the alcohol.
0:08:48 > 0:08:50You make me feel like I'm some alcoholic!
0:08:50 > 0:08:53- Made me feel a little bit upset. - Oh...!
0:08:53 > 0:08:56I'm just trying to explain what's going on at the moment.
0:08:56 > 0:08:58- OK.- I do understand why you've started
0:08:58 > 0:09:01because, in the short term,
0:09:01 > 0:09:03it will be like a crutch and it will calm you down.
0:09:03 > 0:09:06- Yeah.- But in the long term, it just makes the problem worse.- Yeah.
0:09:06 > 0:09:10Emma also drinks two litres of caffeine-filled Diet Coke every day
0:09:10 > 0:09:12and relies on nicotine.
0:09:19 > 0:09:21How often do you have takeaways every week?
0:09:21 > 0:09:23Two or three.
0:09:23 > 0:09:27It's just easier and, you know, obviously it's not ideal,
0:09:27 > 0:09:30but at the same time, it's just like,
0:09:30 > 0:09:32"Here you go, here you go, here you go."
0:09:32 > 0:09:34Everyone's happy, eat your food
0:09:34 > 0:09:37then let's start doing bedtime routines, so...
0:09:37 > 0:09:39She's got her chips, cheese and gravy.
0:09:41 > 0:09:43My God, you're doing much more than you should be.
0:09:43 > 0:09:45No, it's fine. My pleasure.
0:09:45 > 0:09:48Where are we going? Whose is this?
0:09:48 > 0:09:49Oh, that's yours.
0:09:49 > 0:09:52Sorry, I'm walking off with it.
0:09:52 > 0:09:53- Tortillas.- Nachos.
0:09:53 > 0:09:56- Nachos.- With refried beans
0:09:56 > 0:09:59and sour cream
0:09:59 > 0:10:01and little bits of coriander
0:10:01 > 0:10:02and onions and stuff.
0:10:02 > 0:10:05'As a GP in standard surgery,'
0:10:05 > 0:10:08there's just no way you could get the bottom of this.
0:10:08 > 0:10:10It's just simply not going to be possible
0:10:10 > 0:10:15and...now that I've got more time and I'm starting to pick things up,
0:10:15 > 0:10:18frankly, I am so far outside my comfort zone,
0:10:18 > 0:10:20I cannot even tell you.
0:10:20 > 0:10:22There is so much information coming in.
0:10:22 > 0:10:26I actually don't know what I'm going to do with it all.
0:10:29 > 0:10:33In the morning, Rangan commutes with Emma to Liverpool city centre,
0:10:33 > 0:10:35where she works as a PA.
0:10:35 > 0:10:40He wants to see if he can identify potential triggers for her anxiety.
0:10:40 > 0:10:43OK, so we go round here, and this is where my office is, round here.
0:10:43 > 0:10:46Hey, guys, how are you doing? All right?
0:10:46 > 0:10:49- This is Phil.- Hey, Phil. Rangan, nice to meet you, are you all right?
0:10:49 > 0:10:52- And that's Peter. Hey, Peter. - Rangan, how are you doing?
0:10:52 > 0:10:53All right? Nice to meet you.
0:10:53 > 0:10:55Is there anything you do on the computer or the phone
0:10:55 > 0:10:58that can ever make you anxious or panicky?
0:10:58 > 0:11:00Only if I go onto the news pages
0:11:00 > 0:11:02and someone has been murdered or something
0:11:02 > 0:11:05and it's a horrible story, then I'll start thinking...
0:11:05 > 0:11:07- SHE GASPS - Yeah.
0:11:07 > 0:11:08Have you guys seen any of this at all?
0:11:08 > 0:11:11Yeah, you mention space, death,
0:11:11 > 0:11:15anything that is outside of just the realms of average day-to-day
0:11:15 > 0:11:18- and Missy has a panic attack. - Oh, really?
0:11:18 > 0:11:20Oh, yeah. Or, "Stop talking about it," or something.
0:11:20 > 0:11:23If I feel like I am about to go and have a proper panic attack,
0:11:23 > 0:11:25I'll either go and speak to him or I'll just leave
0:11:25 > 0:11:27and go and try and calm myself down.
0:11:27 > 0:11:29I've got up and walked out a couple of times.
0:11:31 > 0:11:35If we're having a terrible day and I'm having a meltdown,
0:11:35 > 0:11:37this is where I go for my wine.
0:11:37 > 0:11:39"Right, let's go get some emergency wine."
0:11:39 > 0:11:41Re-evaluate the situation
0:11:41 > 0:11:43then go back to work in a bit of a calmer state.
0:11:43 > 0:11:46So they're quite understanding. They know that, actually,
0:11:46 > 0:11:48you can sometimes get quite anxious and panicky
0:11:48 > 0:11:51so you need to sometimes come and the wine helps you calm down.
0:11:51 > 0:11:54Yeah. It takes the edge off that...
0:11:54 > 0:11:56- GASPING - ..feeling.
0:11:59 > 0:12:02In Britain, people who experience anxiety or depression
0:12:02 > 0:12:04are twice as likely to be heavy drinkers.
0:12:09 > 0:12:12I'll tell you how I see things that are going on with you, Emma.
0:12:12 > 0:12:14I know that you...
0:12:15 > 0:12:18..have said to me that what happened at 19,
0:12:18 > 0:12:20that whole experience is a big part of this
0:12:20 > 0:12:22but I think, since then,
0:12:22 > 0:12:25in order to try and deal with those symptoms,
0:12:25 > 0:12:27you've probably started to do things
0:12:27 > 0:12:32that actually are making that a lot worse.
0:12:32 > 0:12:33Does that make sense?
0:12:33 > 0:12:35- Go on.- OK.
0:12:35 > 0:12:39So what I'm saying is I think that was a big...a significant incident
0:12:39 > 0:12:43and what that did is probably cause you to have a lot of anxiety attacks
0:12:43 > 0:12:45and these panic attacks,
0:12:45 > 0:12:46but then, because of those panic attacks,
0:12:46 > 0:12:49I think you needed to do things to help you cope with them
0:12:49 > 0:12:53and I think that the things that you're using to cope
0:12:53 > 0:12:55are actually driving the panic attacks to be worse
0:12:55 > 0:12:58and I think it's a vicious cycle that you are in now.
0:12:58 > 0:13:02I think it's going to be very, very hard to unwind this whole...
0:13:03 > 0:13:06..these whole patterns that you've got going on in you.
0:13:06 > 0:13:08I don't think your body's in a state
0:13:08 > 0:13:10where we can even tackle that just yet.
0:13:10 > 0:13:12The two things are - what you're eating
0:13:12 > 0:13:15and how much you're drinking.
0:13:15 > 0:13:19So this is the sort of food that...is not going to be ideal,
0:13:19 > 0:13:22because this is going to put you on a blood sugar roller-coaster.
0:13:22 > 0:13:24It's full of sugar and... Yeah.
0:13:24 > 0:13:29Yeah, it is, and if your blood sugar goes low, OK, just a smidgen low,
0:13:29 > 0:13:32your body goes back in fight or flight.
0:13:32 > 0:13:33You release something called cortisol
0:13:33 > 0:13:36which is a stress hormone, you release adrenaline
0:13:36 > 0:13:38and actually, alcohol will do this as well,
0:13:38 > 0:13:41because it spikes your blood sugar and then you crash.
0:13:41 > 0:13:44That will drive you more into fight or flight
0:13:44 > 0:13:46so we want a diet for you
0:13:46 > 0:13:48that actually stabilises your blood sugar.
0:13:50 > 0:13:52Rangan wants Emma to stop eating sugar,
0:13:52 > 0:13:57processed foods and slowly reduce the amount she drinks by nearly 75%.
0:13:58 > 0:14:01- What do you think, Emma? - I feel like I'm doing it to myself.
0:14:01 > 0:14:03You're not. You'll be all right.
0:14:03 > 0:14:05But, like, that's what I didn't want to hear.
0:14:05 > 0:14:09"You'd be fine if you weren't drinking too much and eating shit."
0:14:12 > 0:14:15It's hardly... You're not eating sweets.
0:14:15 > 0:14:18- No, it's not that. - Eating what normal people eat.
0:14:18 > 0:14:21It's like, "None of this would be happening if I wasn't doing that."
0:14:21 > 0:14:24It's not about blame. I do not think you're doing this to yourself.
0:14:24 > 0:14:27I absolutely understand why you're doing this.
0:14:27 > 0:14:30I'm not criticising, I promise you.
0:14:32 > 0:14:34I would, you know... What I'm asking for
0:14:34 > 0:14:37is to see if you're willing and if you are willing,
0:14:37 > 0:14:38then we can reassess in seven days.
0:14:38 > 0:14:41Re-assess and see, actually, has it made any difference?
0:14:41 > 0:14:44Or has it not? You know?
0:14:44 > 0:14:47And normally, it makes a big difference.
0:14:48 > 0:14:51That was really, really intense.
0:14:55 > 0:14:57I feel quite drained, actually, just from that...
0:14:57 > 0:14:59from that conversation.
0:15:00 > 0:15:02I'm...
0:15:02 > 0:15:05I'm starting to tread on eggshells a little bit because I am feeling
0:15:05 > 0:15:09that I can't... say what I need to say
0:15:09 > 0:15:13because I think Emma feels as though I'm blaming her
0:15:13 > 0:15:14and I'm genuinely not blaming her.
0:15:14 > 0:15:17I do understand why she's making the choices she's making
0:15:17 > 0:15:20but, actually, I think that's a reflection of where she is.
0:15:20 > 0:15:22She is so locked into this fight or flight
0:15:22 > 0:15:26that actually, whatever I say, she's taken that as being blame,
0:15:26 > 0:15:28that she's doing it to herself.
0:15:28 > 0:15:30I actually think that's part of the problem.
0:15:30 > 0:15:32I'll be back to see if you're all right.
0:15:32 > 0:15:33- Thank you so much. - Thank you very much.
0:15:33 > 0:15:36- Take care. See you. - See you, now, bye.
0:15:36 > 0:15:39I don't think changing my eating and drinking
0:15:39 > 0:15:42is going to change...my fear.
0:15:42 > 0:15:44No, well, that's different, isn't it?
0:15:44 > 0:15:47He said that's going to come further down the line,
0:15:47 > 0:15:49but this is to prepare the body, really, for that fight.
0:15:49 > 0:15:52Obviously taking away Diet Coke is going to be a massive thing
0:15:52 > 0:15:53cos anyone who knows me knows
0:15:53 > 0:15:56that I am basically a bottle of Diet Cola,
0:15:56 > 0:16:00so I think that's going to be really, really hard.
0:16:04 > 0:16:07In the meantime, Rangan travels to a second family
0:16:07 > 0:16:10where another parent is struggling to deal with everyday life.
0:16:11 > 0:16:15Sleaford in Lincolnshire is home to the Murray-Hardcroft family.
0:16:17 > 0:16:2011-year-old Ellie and Maeve,
0:16:20 > 0:16:22nine-year-old Charlie...
0:16:22 > 0:16:25- Coat on.- I don't want it on. - It might be chilly outside.
0:16:25 > 0:16:27..Mum, 39-year-old Kelly...
0:16:27 > 0:16:28Right, in you get.
0:16:28 > 0:16:32..and Dad, 36-year-old James.
0:16:32 > 0:16:34Kelly will be back soon.
0:16:34 > 0:16:36Now we can get on with our day.
0:16:37 > 0:16:39Mum and Dad run an IT business together
0:16:39 > 0:16:41and study in further education.
0:16:43 > 0:16:47They've called the doctor for James's unexplained exhaustion.
0:16:47 > 0:16:48When you see your partner at,
0:16:48 > 0:16:51kind of, three or four o'clock in the afternoon,
0:16:51 > 0:16:53barely able to keep their eyes open,
0:16:53 > 0:16:56and you know they're not having quality of life,
0:16:56 > 0:16:58it's quite upsetting.
0:16:59 > 0:17:02James eats healthily, exercises regularly,
0:17:02 > 0:17:04but struggles to sleep.
0:17:04 > 0:17:06At night, I can go into a fever.
0:17:06 > 0:17:09I just sweat profusely,
0:17:09 > 0:17:13literally from the top of my scalp to the soles of my feet.
0:17:13 > 0:17:16Sweats like somebody's thrown a bucket of water on him,
0:17:16 > 0:17:20which isn't pleasant to sleep next to at all.
0:17:20 > 0:17:23And he also, er...
0:17:24 > 0:17:27He struggles with breathing sometimes through the night,
0:17:27 > 0:17:28which wakes me up,
0:17:28 > 0:17:32so he takes a lot of inhales, but doesn't actually exhale at all,
0:17:32 > 0:17:36um...until his breathing has stopped altogether
0:17:36 > 0:17:40and then kind of splutters a little bit and starts again,
0:17:40 > 0:17:43but it's quite scary to be woken up like that.
0:17:43 > 0:17:48James's lack of sleep has taken a toll on his life.
0:17:48 > 0:17:49I can't explain...
0:17:51 > 0:17:55..how every single day of life for 20 years plus
0:17:55 > 0:17:57has felt just like wading through treacle.
0:17:57 > 0:17:59You can't get doctors to listen.
0:17:59 > 0:18:01If doctors don't listen,
0:18:01 > 0:18:03nobody around you is going to listen, either.
0:18:03 > 0:18:05Nothing's wrong with you. If there was something wrong with you,
0:18:05 > 0:18:07you'd be on drugs, you'd be on medication,
0:18:07 > 0:18:09you'd be seeing specialists,
0:18:09 > 0:18:11you'd be referred for this, you know?
0:18:11 > 0:18:14There would be something on paper, somewhere, to explain, actually,
0:18:14 > 0:18:17you're not lazy, you're not just lethargic.
0:18:21 > 0:18:23When patients feel fobbed off by their doctor,
0:18:23 > 0:18:25it can be quite frustrating as a doctor
0:18:25 > 0:18:28because the time constraints mean that, often, we can't actually
0:18:28 > 0:18:30delve into why that is,
0:18:30 > 0:18:32but actually, it's more frustrating for the patients,
0:18:32 > 0:18:35because they're the ones who feel fobbed off.
0:18:36 > 0:18:39James wants Rangan to solve the mystery
0:18:39 > 0:18:42of why exhaustion has ruled his life for the last 20 years.
0:18:44 > 0:18:47- Hello.- Hi, I'm Dr Chatterjee.
0:18:47 > 0:18:49- Hi, I'm James.- Hi, James. - Kelly.- Hi, Kelly.
0:18:49 > 0:18:53So you've known, inside you, for a while...
0:18:53 > 0:18:55- Yeah. - ..something ain't quite right.
0:18:55 > 0:18:57- Yeah.- You've done what is the reasonable thing to do,
0:18:57 > 0:19:00which is you are a busy guy, but you found time
0:19:00 > 0:19:03to go and see your doctor, flag a few of these things up.
0:19:03 > 0:19:07You go to your doctor and you say, "I'm tired,
0:19:07 > 0:19:09"I'm sweating at night profusely.
0:19:09 > 0:19:12"I stop breathing when I'm asleep."
0:19:12 > 0:19:15And they just basically say, "There's nothing wrong with you."
0:19:15 > 0:19:18- Yeah.- "Go home, and if it happens again, come back."
0:19:18 > 0:19:20Well, I've been doing that for years.
0:19:20 > 0:19:22And how do you feel about that, now?
0:19:22 > 0:19:25I'm pretty...bitter.
0:19:25 > 0:19:29- Is that it? That's how you feel? - I'm quite bitter.
0:19:29 > 0:19:31You don't look like someone who is out of shape,
0:19:31 > 0:19:33so doctors are already probably thinking,
0:19:33 > 0:19:35"Yeah, he's in decent shape."
0:19:36 > 0:19:38Rangan begins looking for clues
0:19:38 > 0:19:40that could point to the cause of James's illness.
0:19:40 > 0:19:43Yes, so this is just a very, very brief exam,
0:19:43 > 0:19:45I just want to see if I can pick anything else up, OK?
0:19:45 > 0:19:47Take your pulse.
0:19:47 > 0:19:50Listen to your heart.
0:19:50 > 0:19:51Deep breath in, please.
0:19:52 > 0:19:53Your blood pressure.
0:19:56 > 0:19:58OK, that's a little bit elevated,
0:19:58 > 0:20:01it's 144/93.
0:20:02 > 0:20:05Your history is making me concerned
0:20:05 > 0:20:07that you may have some sleep apnoea.
0:20:07 > 0:20:10The full term is obstructive sleep apnoea.
0:20:10 > 0:20:12There's an obstruction in your airway,
0:20:12 > 0:20:14which is basically meaning that you stop breathing
0:20:14 > 0:20:17at regular intervals whilst you're asleep.
0:20:17 > 0:20:21What's happening is every time you have an episode
0:20:21 > 0:20:24where you stop breathing, it can often be the equivalent
0:20:24 > 0:20:30of you going from sea level, up to base camp at Mount Everest,
0:20:30 > 0:20:33back and forth, ten times in an hour.
0:20:33 > 0:20:37- That's the strain it's putting on your body.- OK.- Oxygenation.
0:20:37 > 0:20:40Oxygenation, yes. Does that make it a bit clearer?
0:20:40 > 0:20:42Yeah. Yeah, it does.
0:20:43 > 0:20:46And that potentially might explain
0:20:46 > 0:20:49- why you are so tired sometimes in the day.- Yeah.
0:20:52 > 0:20:54Rangan spends the evening with the family
0:20:54 > 0:20:56to see James's symptoms first-hand.
0:20:58 > 0:21:00He looks exhausted to me.
0:21:00 > 0:21:02Yeah, so this is actually quite normal
0:21:02 > 0:21:04for James to be this tired.
0:21:04 > 0:21:07He would quite happily go to bed with the kids.
0:21:07 > 0:21:09- So, at eight o'clock.- Really?
0:21:09 > 0:21:11Yeah, absolutely.
0:21:11 > 0:21:14Sometimes, just to have a partner on the evening,
0:21:14 > 0:21:17I have to literally, kind of, not beg him, but say,
0:21:17 > 0:21:19"Actually, I'd really like your company,
0:21:19 > 0:21:21- "can you just stay awake a little longer?"- Right.
0:21:23 > 0:21:25What I'd like to do for you is
0:21:25 > 0:21:29to have a look at exactly what's going on when you are asleep
0:21:29 > 0:21:32and see if we can come up with a proper diagnosis
0:21:32 > 0:21:36as to what these sleep issues are, and therefore, that will help me
0:21:36 > 0:21:39determine what sort of treatment we need to give you.
0:21:39 > 0:21:40Right, OK.
0:21:42 > 0:21:44Rangan fits James with a device
0:21:44 > 0:21:47to record his breathing and heart rate throughout the night.
0:21:47 > 0:21:48How does that feel?
0:21:50 > 0:21:52- Great(!) - LAUGHTER
0:21:52 > 0:21:55Keep it on all night, we'll get this back
0:21:55 > 0:21:58- to the sleep clinic tomorrow.- Yeah.
0:21:58 > 0:22:02- And then, hopefully, we'll have some results very shortly.- OK.
0:22:02 > 0:22:06- OK, thanks very much.- Sleep well. See you, Kelly. See you.
0:22:10 > 0:22:13Through the night, the equipment will register
0:22:13 > 0:22:16if James's throat muscles relax to the point of collapse,
0:22:16 > 0:22:18blocking his airway for ten seconds or more,
0:22:18 > 0:22:21which would indicate an episode of sleep apnoea.
0:22:27 > 0:22:30A few days later, Rangan, James and Kelly
0:22:30 > 0:22:34head to London for the results of the sleep study.
0:22:34 > 0:22:36I think James just wants to know what's going on, so he can fix it.
0:22:36 > 0:22:40This is having such a massive impact on his life.
0:22:40 > 0:22:45His ability to be a father, interaction with his children.
0:22:45 > 0:22:48I think he's really excited that we might actually
0:22:48 > 0:22:49get to the bottom of this today.
0:22:50 > 0:22:53- Hi.- Hi, how are you? - Good to see you.- Yes, good, thanks.
0:22:53 > 0:22:57Dr Singh is the consultant in charge of the sleep clinic.
0:22:57 > 0:22:59He's analysed James's results.
0:23:00 > 0:23:04- It was a good study.- Excellent. - So in spite of, sort of, concerns,
0:23:04 > 0:23:08the study measured about six hours and 25 minutes.
0:23:08 > 0:23:11- Terrific.- There were no episodes in this study
0:23:11 > 0:23:14where your airway closed down completely.
0:23:14 > 0:23:19- Right.- That means that, actually, this respiratory sleep study
0:23:19 > 0:23:23was a normal study, meaning we can, with a degree of confidence,
0:23:23 > 0:23:26rule out obstructive sleep apnoea.
0:23:26 > 0:23:28- Excellent.- Which is very good, and it's very important.
0:23:28 > 0:23:31We are not looking at sleep-disordered breathing here.
0:23:31 > 0:23:36- OK.- So we've not only ruled out obstructive sleep apnoea...
0:23:36 > 0:23:38- Yes.- ..we've also ruled out other conditions that fall under
0:23:38 > 0:23:41- the umbrella of sleep-disordered breathing?- In a sense, that's right.
0:23:41 > 0:23:44Obviously, we need to dig a bit deeper now and find out,
0:23:44 > 0:23:46actually, what is going on.
0:23:48 > 0:23:50Yeah, so how do you feel?
0:23:50 > 0:23:52Do you know, I'm not sure.
0:23:52 > 0:23:53Nothing is cut and dry, is it?
0:23:53 > 0:23:57There's no immediate answer right now.
0:23:57 > 0:23:58And I think,
0:23:58 > 0:24:02I think that was one of the things I was afraid of, you know,
0:24:02 > 0:24:07coming in today, was that there would be no immediate solution.
0:24:07 > 0:24:10We're no closer to a solution, we're further away.
0:24:10 > 0:24:12That's the problem, we're still in limbo with it.
0:24:12 > 0:24:15- I think we are closer, Kelly. - Do you think?- I know...
0:24:15 > 0:24:18Closer in the sense that... you know, a few weeks ago...
0:24:19 > 0:24:22..nothing was happening, this was just normality.
0:24:22 > 0:24:25- This was just something we had to live with.- Yeah.- Yeah.
0:24:29 > 0:24:32HE SIGHS
0:24:32 > 0:24:34That was a little bit surprising.
0:24:34 > 0:24:38I did not really think that that was going to be the outcome
0:24:38 > 0:24:40of the sleep clinic today.
0:24:40 > 0:24:43I think it's a good thing, I think it's a really good thing,
0:24:43 > 0:24:47that James does not have sleep-disordered breathing,
0:24:47 > 0:24:48I think that's brilliant.
0:24:48 > 0:24:50The question is, what does he have?
0:24:59 > 0:25:01I'm just in a really, really bad mood.
0:25:01 > 0:25:05In Liverpool, Emma is struggling with Rangan's new diet.
0:25:06 > 0:25:09The last thing I want is stupid avocado for my dinner,
0:25:09 > 0:25:13I want a pasty. It's so funny and stupid at the same time.
0:25:13 > 0:25:16She's been battling anxiety and has been relying on a cocktail
0:25:16 > 0:25:19of antidepressants, alcohol, nicotine,
0:25:19 > 0:25:21caffeine and high-sugar foods.
0:25:21 > 0:25:23Eating a big bar of chocolate and a packet of crisps
0:25:23 > 0:25:26would make me well happier right now than a bowl of healthy soup.
0:25:26 > 0:25:27Rangan is very slowly
0:25:27 > 0:25:30trying to reduce her reliance on these substances.
0:25:30 > 0:25:32I'll close down if I stop drinking it.
0:25:32 > 0:25:34But she's not finding it easy.
0:25:34 > 0:25:36Crying over chocolate. Who cries over chocolate?
0:25:36 > 0:25:38I don't even like chocolate.
0:25:40 > 0:25:45I think that, basically, Emma lives in fight or flight.
0:25:45 > 0:25:48I think, if I make one wrong move,
0:25:48 > 0:25:50she could lose faith in me,
0:25:50 > 0:25:52and I think the whole thing falls down then.
0:25:53 > 0:25:56Rangan hopes that a lesson in nutrition
0:25:56 > 0:25:59might give Emma the motivation she needs.
0:26:02 > 0:26:04The food you eat can really affect your mood
0:26:04 > 0:26:07and how your brain operates, basically.
0:26:07 > 0:26:10And so I thought we could actually go through some of the foods
0:26:10 > 0:26:11that might help you.
0:26:11 > 0:26:14You know, healthy gut, healthy brain, basically.
0:26:14 > 0:26:17It's hard, it's like your junk food is your friend, isn't it?
0:26:17 > 0:26:19When you're feeling down, it's, like, your go-to thing.
0:26:19 > 0:26:22To replace it... I mean, I don't know.
0:26:22 > 0:26:25Maybe it will make me feel better, so it's worth trying it.
0:26:25 > 0:26:30Leafy green vegetables can actually, basically,
0:26:30 > 0:26:32drive the growth of good bacteria in your gut,
0:26:32 > 0:26:34that can really help with your brain.
0:26:34 > 0:26:38So having things like cauliflower, broccoli...
0:26:38 > 0:26:40- Would you have foods like this? - Yeah.- What have we got here?
0:26:40 > 0:26:41- Cabbage.- Cabbage.
0:26:41 > 0:26:44Look at that. That looks great to me.
0:26:44 > 0:26:46I can see the snail marks on it, though.
0:26:46 > 0:26:49Why is it you don't like the snail marks?
0:26:49 > 0:26:51It would be like licking a snail's bum, wouldn't it?
0:26:51 > 0:26:52LAUGHTER
0:26:52 > 0:26:55It's just left its stuff out as it goes along.
0:26:55 > 0:26:57Tell you what, I'm going to hide that, then,
0:26:57 > 0:26:58cos we can wash that off.
0:26:58 > 0:27:01There's another chemical that we find in food
0:27:01 > 0:27:03that can be really helpful for our brain.
0:27:03 > 0:27:04It's called tryptophan.
0:27:04 > 0:27:05OK, so tryptophan helps us make
0:27:05 > 0:27:08something called serotonin in our bodies.
0:27:08 > 0:27:10Serotonin is, you know,
0:27:10 > 0:27:13many scientists call it like a happy chemical in our brain.
0:27:13 > 0:27:17And there's certain foods, pork contains tryptophan -
0:27:17 > 0:27:19so would you ever eat pork?
0:27:19 > 0:27:21- Yeah.- Let me just go and grab something.
0:27:23 > 0:27:26Emma, would you ever eat things like this, sweet potatoes?
0:27:26 > 0:27:32- Yes.- Yeah? Good, because if you have a healthy form of carbohydrate,
0:27:32 > 0:27:37like sweet potatoes, it really helps you to absorb the tryptophan.
0:27:37 > 0:27:38Here, Emma.
0:27:38 > 0:27:39Perfect.
0:27:41 > 0:27:44OK. Walnuts are like a double whammy.
0:27:44 > 0:27:48OK, because walnuts contain omega 3 fats,
0:27:48 > 0:27:51so these are fats that we think are really good for our brain function,
0:27:51 > 0:27:54and we can't get them unless we take them in by our diets.
0:27:54 > 0:27:56- Our bodies can't make them. - OK.- OK?
0:27:56 > 0:28:00So these are full of omega 3 fats, which is absolutely brilliant.
0:28:00 > 0:28:03The other thing they've got is tryptophan.
0:28:03 > 0:28:05No, I've never made the connection before,
0:28:05 > 0:28:09about what you eat having any form of repercussion on your mood or anything like that,
0:28:09 > 0:28:12that's not something I'd ever known, especially all these fancy words
0:28:12 > 0:28:14that are in stuff, you just don't realise.
0:28:14 > 0:28:16I don't think it's necessarily the whole story with you,
0:28:16 > 0:28:18but I think it's a great start.
0:28:18 > 0:28:21I wonder what Trev will think when we come back with all this food.
0:28:21 > 0:28:25He'll probably wonder where his chippy tea is.
0:28:25 > 0:28:26Right, all done.
0:28:27 > 0:28:30Rangan's diet plan is a world away
0:28:30 > 0:28:32from takeaway dinners and bottles of Diet Coke.
0:28:32 > 0:28:34What are you cooking?
0:28:34 > 0:28:37So, I'm making tomato soup.
0:28:37 > 0:28:39Emma perseveres with the diet...
0:28:39 > 0:28:42I'm making a stewy, soupy thing.
0:28:42 > 0:28:44..and Rangan keeps up the encouragement.
0:28:44 > 0:28:46How have you been getting on this week?
0:28:46 > 0:28:50If anything, I've been a bit more anxious because I've taken the comfort blanket away.
0:28:50 > 0:28:52What's on my desk this week, Peter, that's unusual?
0:28:52 > 0:28:55Pears. And water.
0:28:55 > 0:28:57So, I've got boiled eggs
0:28:57 > 0:29:01and home-made guacamole with chilli flakes and stuff
0:29:01 > 0:29:02that I made last night.
0:29:02 > 0:29:05- You made it yourself?- Yeah, getting good at this cooking lark now.
0:29:05 > 0:29:08By reducing her alcohol and changing her diet,
0:29:08 > 0:29:12Rangan is slowly preparing Emma for the next stage of her treatment.
0:29:12 > 0:29:14I'd love to get her to talking therapy.
0:29:14 > 0:29:18The research would tell me to send her to a behavioural therapist,
0:29:18 > 0:29:20a cognitive behavioural therapist.
0:29:20 > 0:29:23But Emma, the patient, is telling me she doesn't want that.
0:29:23 > 0:29:26So that's why I've had to go and research something else.
0:29:26 > 0:29:30Instead of therapy, where Emma talks about her issues,
0:29:30 > 0:29:33Rangan wants to try an alternative treatment
0:29:33 > 0:29:36that combines massage with counselling.
0:29:36 > 0:29:41You can, with some patients, actually help reduce stress hormones
0:29:41 > 0:29:43like cortisol and adrenaline by physical touch,
0:29:43 > 0:29:45and Hayley is very skilled at that,
0:29:45 > 0:29:48and I thought it would be worth trying it, because then,
0:29:48 > 0:29:50you don't have to think about things and talk about things.
0:29:50 > 0:29:52- But we could see.- Yeah. - Does that...?
0:29:52 > 0:29:55No, I'm willing to give it a go, cos obviously, I trust you.
0:29:55 > 0:29:57So it's just a case of going and doing it.
0:29:57 > 0:30:01But I've never had a massage anyway, so I'm scared of anything. Scared of new things.
0:30:01 > 0:30:03You've basically been doing what I've asked you to do,
0:30:03 > 0:30:05which is substantially change your diet,
0:30:05 > 0:30:07substantially reduce how much you're drinking.
0:30:07 > 0:30:10That's fantastic, but I do think we need to do more,
0:30:10 > 0:30:12and let's go and see Hayley
0:30:12 > 0:30:16and see if she may be someone who can help us.
0:30:16 > 0:30:17- OK.- Yeah?
0:30:17 > 0:30:21Rangan has brought Emma to meet Hayley Stevens.
0:30:21 > 0:30:23- This is Emma.- Hi, Emma.
0:30:23 > 0:30:27She specialises in biodynamic massage.
0:30:27 > 0:30:31I just want you to bring your awareness to your breath right now
0:30:31 > 0:30:33and I just want you to tell me what you notice.
0:30:33 > 0:30:36What do you notice about your breathing right now?
0:30:36 > 0:30:38- I don't know.- OK.
0:30:38 > 0:30:40I can't focus on my breathing too much
0:30:40 > 0:30:42because it'll remind me that I'm alive
0:30:42 > 0:30:45and then I can die and I'll have a panic attack, thanks(!)
0:30:45 > 0:30:47OK, so you don't want to focus on your breathing?
0:30:47 > 0:30:48- No, not really.- OK.
0:30:50 > 0:30:54There's nothing here right now that is going on,
0:30:54 > 0:30:57that is happening, that is scary right now.
0:30:59 > 0:31:02The whole situation is scary because I've never been here,
0:31:02 > 0:31:04- I've never done this, so of course it's scary.- It is.
0:31:04 > 0:31:07What's happening on a day-to-day basis
0:31:07 > 0:31:09that you say "God, I'm afraid"?
0:31:09 > 0:31:13Yes, well, anything that really reminds me that I'm alive
0:31:13 > 0:31:14reminds me that I'm going to die.
0:31:14 > 0:31:17- OK.- Um...I don't know, I'm going to cry again.
0:31:17 > 0:31:20I've been like this all week, I don't know what my issue is.
0:31:20 > 0:31:21OK.
0:31:25 > 0:31:28Can you just leave us for a few moments?
0:31:28 > 0:31:30- Yes, of course, definitely. - OK, thank you.- OK, OK...
0:31:33 > 0:31:35I don't think I really appreciated
0:31:35 > 0:31:38that even the small amount of chat that Hayley had to do with her
0:31:38 > 0:31:40was going to be too much.
0:31:41 > 0:31:44I thought, at the very least today, I would do no harm.
0:31:46 > 0:31:49And there was a short period where I thought...
0:31:49 > 0:31:51"I'm not so sure, I'm not so sure.
0:31:51 > 0:31:54"Have I eroded trust? have I made things worse?"
0:31:54 > 0:31:57If I don't find something soon
0:31:57 > 0:31:59that she's going to start responding to,
0:31:59 > 0:32:02I wonder how long that trust will last.
0:32:02 > 0:32:07Emma leaves the session before the massage therapy even begins.
0:32:07 > 0:32:08I felt like I'd let everyone down
0:32:08 > 0:32:11because everyone had travelled all this way,
0:32:11 > 0:32:13it was all this big thing to go for this massage
0:32:13 > 0:32:17and then I just...I said to her, "I'm just too crazy for you."
0:32:17 > 0:32:18That's what it is.
0:32:18 > 0:32:22I'm not mentally well enough for her to start touching me
0:32:22 > 0:32:24and trying to get emotions out of me with massage.
0:32:24 > 0:32:27All you can do is go back to the drawing board
0:32:27 > 0:32:30and think of something else.
0:32:30 > 0:32:33How about some emotional support, how does that pan out for you?
0:32:33 > 0:32:36Yeah, and we can watch a horror film in bed, cos you like them.
0:32:38 > 0:32:41Yes, again, but what about the emotional support side of things?
0:32:41 > 0:32:42Well, yeah.
0:32:44 > 0:32:46Yeah, but I'm not a big talker.
0:32:47 > 0:32:50But, yeah, I can be there for you.
0:32:55 > 0:32:58You'll be fine, come here, you'll be fine, don't worry.
0:33:01 > 0:33:04Obviously today was a little bit disappointing for her,
0:33:04 > 0:33:07but now I've got to support her really more.
0:33:08 > 0:33:11What happened today, it sort of brought emotions up
0:33:11 > 0:33:17and things that she might not want to talk about, to me or to anyone.
0:33:17 > 0:33:19She'll probably get drunk tonight
0:33:19 > 0:33:23and just talk to me when she is drunk, you know?
0:33:29 > 0:33:32In Lincolnshire, Rangan is trying to get to the bottom
0:33:32 > 0:33:36of James's mysterious, debilitating exhaustion.
0:33:36 > 0:33:38He now knows it's not a sleep disorder,
0:33:38 > 0:33:40so he's sent James for blood tests,
0:33:40 > 0:33:43and is hunting for more clues in his daily routine.
0:33:44 > 0:33:49I think James is still a little bit of a mystery because he's exhausted,
0:33:49 > 0:33:53he can't sleep, he wakes up in sweats,
0:33:53 > 0:33:56but he looks fit and well, and he comes here all the time.
0:33:56 > 0:34:00But it's not normal for someone in their 30s to be like this.
0:34:00 > 0:34:02I need to keep digging, I think, and see,
0:34:02 > 0:34:04can I detect something else?
0:34:04 > 0:34:07OK, your heart rate is 120, it's regular.
0:34:07 > 0:34:10What I'd call good volume, good weight,
0:34:10 > 0:34:14nothing untoward from feeling your pulse.
0:34:14 > 0:34:16With James appearing physically healthy,
0:34:16 > 0:34:19Rangan moves his investigation to his mental health.
0:34:20 > 0:34:22So, James, do you get anxious
0:34:22 > 0:34:24about things in general, would you say?
0:34:24 > 0:34:25Yeah.
0:34:25 > 0:34:27I'm very good at covering it up.
0:34:27 > 0:34:32Because I have a tendency to not become, sort of, physically irate,
0:34:32 > 0:34:36I'm good at keeping a calm voice and, sort of, approaching things
0:34:36 > 0:34:38from what appears to be a very level-headed perspective,
0:34:38 > 0:34:42but I do, I am anxious about a lot of things.
0:34:42 > 0:34:43Do you know where this comes from?
0:34:43 > 0:34:48I've had some pretty unstable...points in life.
0:34:50 > 0:34:52- And... - What do you mean by that?
0:34:52 > 0:34:57I ended up...not a fixed address, for a while.
0:34:58 > 0:35:01- So were you sleeping on the streets? - Yeah.- Yeah.
0:35:01 > 0:35:05Usually, I would find somewhere a bit prettier than a street,
0:35:05 > 0:35:07it would be a park, you know, somewhere...
0:35:08 > 0:35:10So how long were you...?
0:35:10 > 0:35:13Would you say you were homeless for a while?
0:35:13 > 0:35:15Yeah, I was homeless for a while.
0:35:16 > 0:35:18After a fall-out with his parents,
0:35:18 > 0:35:22James found himself homeless in his late teens.
0:35:22 > 0:35:24There were times when I had to sleep here
0:35:24 > 0:35:26and I would tuck myself away behind the shrubbery
0:35:26 > 0:35:30and basically put myself, wherever I would be, out of sight.
0:35:30 > 0:35:33But I did once get urinated on. The guy was drunk.
0:35:33 > 0:35:37And do you think that sleeping in parks like this one
0:35:37 > 0:35:42has actually contributed to anxiety about yourself,
0:35:42 > 0:35:45anxiety about the next meal, anxiety...
0:35:45 > 0:35:47just general anxiety in your life?
0:35:47 > 0:35:52The problem is, it's kind of hard as the person in it
0:35:52 > 0:35:55to be able to say for sure, but...
0:35:55 > 0:35:58Um...I've described before,
0:35:58 > 0:36:01there are times when I've woken up...
0:36:01 > 0:36:04er, feeling cold wind.
0:36:04 > 0:36:07Obviously, I can't feel cold wind - I'm in a house, the heating's on.
0:36:07 > 0:36:09But there are times when I've woken up
0:36:09 > 0:36:12actually feeling like the cold wind is making my joints ache.
0:36:12 > 0:36:15- As if you were right here in this park?- Yes.- Wow.
0:36:15 > 0:36:18I am still angry about it, I know I'm still angry about it,
0:36:18 > 0:36:23and I know I still have trouble justifying how it happened.
0:36:26 > 0:36:28The period of time before you were homeless,
0:36:28 > 0:36:31do you recall having sleep issues?
0:36:31 > 0:36:33- Vaguely.- Vaguely.
0:36:33 > 0:36:35But nothing on the level?
0:36:35 > 0:36:37Nothing of that level.
0:36:37 > 0:36:39So it's reasonable to think
0:36:39 > 0:36:44that anxiety induced by you being homeless for a period of time
0:36:44 > 0:36:47may be contributing to your sleep issues?
0:36:47 > 0:36:50- Yeah.- Yeah?- Yeah, I think so. I think it's logical.
0:36:54 > 0:36:58But Rangan's research into James's anxiety is interrupted
0:36:58 > 0:37:00when he receives some disturbing blood results.
0:37:02 > 0:37:06So I did a series of blood tests on you
0:37:06 > 0:37:10and one of the markers is a little bit worrying, OK?
0:37:10 > 0:37:13- Right.- There's a marker called homocysteine,
0:37:13 > 0:37:18and homocysteine... can be a risk factor
0:37:18 > 0:37:21for heart attacks and strokes, if it's this elevated.
0:37:21 > 0:37:23Right.
0:37:23 > 0:37:25Now, ideally, we want to see it under ten.
0:37:25 > 0:37:29- Yours is well above 30. - Wow.- Right.
0:37:29 > 0:37:31That's very high, OK?
0:37:31 > 0:37:35And...homocysteine is an amino acid
0:37:35 > 0:37:39that we should metabolise and break down in our body,
0:37:39 > 0:37:41but for some reason, that's not happening in you.
0:37:41 > 0:37:44So that's accumulating in your blood
0:37:44 > 0:37:49and whilst that is elevated, it can damage your blood vessels,
0:37:49 > 0:37:53which, in the long term, can then put you at increased risk
0:37:53 > 0:37:55of a heart attack or a stroke.
0:37:55 > 0:37:59Would that be... Could that be the way it is
0:37:59 > 0:38:02because of the mini-stroke James had when he was younger?
0:38:02 > 0:38:04Can you tell me a little bit about that?
0:38:04 > 0:38:07I woke up one day feeling very much like I had a hangover.
0:38:07 > 0:38:13And after living with that for about four weeks,
0:38:13 > 0:38:15went to the doctor.
0:38:15 > 0:38:19It was implied I may have had a TIA.
0:38:19 > 0:38:21A TIA, or mini stroke,
0:38:21 > 0:38:24is when blood to the brain is temporarily disrupted.
0:38:24 > 0:38:27In the UK, there are nearly 50,000 new cases every year.
0:38:27 > 0:38:31So, 14 years ago, you had this incident for a few weeks that...
0:38:31 > 0:38:34The doctor is saying it may well have been a mini stroke.
0:38:34 > 0:38:36Yeah, that was really all they could put it down to.
0:38:36 > 0:38:40OK. And since then, in this 14-year period,
0:38:40 > 0:38:43has anything like that ever happened again?
0:38:43 > 0:38:47I have... I've had a lot of, sort of,
0:38:47 > 0:38:48physical ups and downs, haven't I?
0:38:48 > 0:38:50In the last few months, you've had...
0:38:50 > 0:38:53We put it down to low blood pressure,
0:38:53 > 0:38:54where he would go...
0:38:54 > 0:38:56You could see the blood drain from his face
0:38:56 > 0:39:00and he was very light-headed and we went to the doctors
0:39:00 > 0:39:03and they kind of dismissed that part of it.
0:39:03 > 0:39:06The blood tests flagged something up for me.
0:39:06 > 0:39:08His history flagged something up for me.
0:39:08 > 0:39:12But now that I've reported it back and gone into it in depth with him,
0:39:12 > 0:39:14there's so much more there.
0:39:14 > 0:39:17He may have had a mini-stroke when he was 21 - I didn't know that.
0:39:17 > 0:39:18That is hugely significant.
0:39:18 > 0:39:20I am worried about him, really worried
0:39:20 > 0:39:23that he is a walking time bomb.
0:39:25 > 0:39:26With this new information,
0:39:26 > 0:39:29Rangan immediately begins further research.
0:39:29 > 0:39:33So, James is a 36-year-old male, extreme fatigue,
0:39:33 > 0:39:37sleep quality is very poor, significant night sweats.
0:39:37 > 0:39:39Breathing issues at night.
0:39:39 > 0:39:42A mini-stroke when he was 21 years old.
0:39:45 > 0:39:48Rangan decides the most urgent step
0:39:48 > 0:39:50is to lower his very high homocysteine levels
0:39:50 > 0:39:53to reduce the risk of him having a stroke.
0:39:55 > 0:39:57After consulting professors of pharmacology,
0:39:57 > 0:40:01he decides to use a combination of powerful vitamins.
0:40:01 > 0:40:04What I've got for you is a supplement
0:40:04 > 0:40:07that actually contains a few things, OK?
0:40:07 > 0:40:10It contains B12, which is a vitamin.
0:40:10 > 0:40:14It contains vitamin B6, and it contains folate.
0:40:14 > 0:40:19OK, and they're all interlinked with pathways in the body
0:40:19 > 0:40:22that can generate energy, that can potentially be linked
0:40:22 > 0:40:25with a risk for heart attacks or strokes,
0:40:25 > 0:40:27and so I want you to take these
0:40:27 > 0:40:31and see if, by supplementing these nutrients in your body,
0:40:31 > 0:40:33whether it changes the way you feel.
0:40:33 > 0:40:35- OK.- Yeah?- Yeah.
0:40:35 > 0:40:36It can't make me worse.
0:40:36 > 0:40:38HE LAUGHS
0:40:38 > 0:40:42And I just think, maybe, this could be part of the puzzle
0:40:42 > 0:40:45with what you've been struggling with for the last 10, 15 years.
0:40:45 > 0:40:47This could be part of the puzzle.
0:40:47 > 0:40:51Rangan gives James a combination of B vitamins,
0:40:51 > 0:40:55including 400 times the recommended daily dose of vitamin B12.
0:41:01 > 0:41:05Two rump steaks, two chicken breasts...
0:41:05 > 0:41:08Emma's visit to the therapist ended in failure,
0:41:08 > 0:41:11and Rangan was concerned she'd lost faith in him.
0:41:11 > 0:41:15But she's persevering with his diet and reducing her alcohol.
0:41:15 > 0:41:19Hello, Dr Scott. It's Dr Chatterjee here.
0:41:19 > 0:41:20Oh, hi.
0:41:20 > 0:41:22Rangan is still searching for another treatment
0:41:22 > 0:41:24that could help her.
0:41:24 > 0:41:26I want to talk to lots of different therapists,
0:41:26 > 0:41:28really get an understanding - what are they going to offer,
0:41:28 > 0:41:32what their strategy is, and also try to make a judgment
0:41:32 > 0:41:34of who I think Emma is going to get on with.
0:41:34 > 0:41:37He speaks to psychiatrists, psychologists
0:41:37 > 0:41:38and experts in anxiety.
0:41:38 > 0:41:43I'm trying to find someone to help her deal with what happens,
0:41:43 > 0:41:46but in a way that is consistent with what she wants also.
0:41:46 > 0:41:49We can say a patient has tried cognitive behavioural therapy,
0:41:49 > 0:41:51but what does it actually mean?
0:41:51 > 0:41:54Have they seen a good therapist, first of all?
0:41:54 > 0:41:56He draws up a short list.
0:41:56 > 0:41:59I've got a good feeling about this, I've got a feeling that, actually,
0:41:59 > 0:42:03what you're offering may be exactly what Emma needs.
0:42:03 > 0:42:05- Hey, how are you doing? - All right, yeah.
0:42:05 > 0:42:06- Good to see you. You OK? - Yeah, come in.
0:42:06 > 0:42:08How are the panic attacks at the moment?
0:42:08 > 0:42:12I've had more over the past couple of weeks than I was having.
0:42:12 > 0:42:15That might just be because my brain is more clear
0:42:15 > 0:42:19and I can hear the little thing that keep saying things to me.
0:42:19 > 0:42:21I'm really very, very proud of what you have done,
0:42:21 > 0:42:23I think it's amazing.
0:42:23 > 0:42:25But I think we do need to think about
0:42:25 > 0:42:29how am I going to get you some sort of therapy to help you.
0:42:29 > 0:42:31I've spoken to quite a lot of people,
0:42:31 > 0:42:34and I've narrowed it down to about three people
0:42:34 > 0:42:37who, I think, offer something very different
0:42:37 > 0:42:41and I'd be very keen for you to chat to them and see what you think.
0:42:41 > 0:42:44- So should we go to call number one? - OK.
0:42:44 > 0:42:48But just before they start, Emma gets cold feet.
0:42:48 > 0:42:52- I don't want to be a pain. - Emma, you're not going to be a pain,
0:42:52 > 0:42:54and this is not about being a pain, OK?
0:42:54 > 0:42:59It doesn't matter - this has been, you know, it's been...
0:42:59 > 0:43:02You have to stop worrying about being a pain, OK?
0:43:02 > 0:43:04I'm here to try and help you, OK?
0:43:04 > 0:43:07So, the people I've found are with that in mind.
0:43:07 > 0:43:13- If I haven't found someone who you can relate to, that's OK.- OK.
0:43:16 > 0:43:18Hi, yeah, nice to see you, too. This is Emma.
0:43:18 > 0:43:22- Hi, Emma.- Emma, this is Charlotte.
0:43:22 > 0:43:24Emma, this is Steve. Steve, Emma.
0:43:24 > 0:43:26- Hiya.- Hi, pleased to meet you.
0:43:26 > 0:43:27Emma, Heather. Heather, Emma.
0:43:27 > 0:43:29- Hiya.- All right?
0:43:29 > 0:43:33I've worked with about 5,500 people.
0:43:33 > 0:43:35After an afternoon of talking with the therapists,
0:43:35 > 0:43:39Emma chooses Charlotte Copeland.
0:43:39 > 0:43:42I liked her. She talks like a normal person,
0:43:42 > 0:43:45and some of the stuff she said made sense.
0:43:45 > 0:43:48For the first time in 15 years,
0:43:48 > 0:43:51Emma has found a therapist she wants to speak to.
0:43:51 > 0:43:53This has been a good day.
0:43:53 > 0:43:57It's probably the first time that I've actually really felt that,
0:43:57 > 0:43:59you know what, we're moving in the right direction.
0:43:59 > 0:44:04I'm hopeful at the moment, I'm optimistic, but I'm cautious.
0:44:08 > 0:44:11A few days later, Trevor and Emma are travelling
0:44:11 > 0:44:14to meet her new therapist, Charlotte.
0:44:14 > 0:44:17So, are you looking forward to this or what?
0:44:17 > 0:44:20Are you excited about seeing this lady, or...?
0:44:20 > 0:44:21I wouldn't say excited.
0:44:21 > 0:44:24I'm... Like I said, I'm apprehensive, so it's just...
0:44:26 > 0:44:28It's cos it's delving into the unknown, isn't it?
0:44:28 > 0:44:33And figuring out whether... she can help me,
0:44:33 > 0:44:37or what ways that she'll come up with to try and help me.
0:44:37 > 0:44:38You're not going to talk about,
0:44:38 > 0:44:41like, your deepest, darkest feelings and stuff like that,
0:44:41 > 0:44:46it's going to be just assessing each other, basically, isn't it?
0:44:51 > 0:44:54- Hi.- Hi.- Hiya, you OK?
0:44:54 > 0:44:57- You must be Emma.- Yes.- Hi.
0:44:57 > 0:44:59It might work and it might not, we don't know,
0:44:59 > 0:45:02it's just something she's going to have to try.
0:45:02 > 0:45:04Obviously, Rangan thinks that it might be
0:45:04 > 0:45:06the right thing for her to do.
0:45:06 > 0:45:10Emma and Charlotte spend over an hour
0:45:10 > 0:45:12in their first session together,
0:45:12 > 0:45:14and there's a significant diagnosis.
0:45:14 > 0:45:17Emma clearly has post-traumatic stress disorder
0:45:17 > 0:45:19and she meets all of the criteria for that.
0:45:19 > 0:45:22There has to be an event that's significant
0:45:22 > 0:45:24that we feel our life, or somebody that's significant to us,
0:45:24 > 0:45:26their life, was under threat.
0:45:26 > 0:45:29It has to be traumatic, an unusual event.
0:45:29 > 0:45:31Emma falls into that category of -
0:45:31 > 0:45:32our mood changes,
0:45:32 > 0:45:35how our behaviour changes.
0:45:35 > 0:45:38We either feel numb or we do things to numb ourselves,
0:45:38 > 0:45:41like drink, for instance.
0:45:41 > 0:45:46This isn't in her imagination, it's very real and very treatable.
0:45:48 > 0:45:49Where's your glass?
0:45:49 > 0:45:51Post-traumatic stress disorder
0:45:51 > 0:45:53is thought to affect one in three people
0:45:53 > 0:45:55who've had a traumatic experience.
0:45:55 > 0:45:59Once diagnosed, talking therapy is often the best treatment.
0:45:59 > 0:46:03She gave me that thing where I felt she wouldn't just have me in bits
0:46:03 > 0:46:06- and let me walk out on the street. - No.- And she even said that herself.
0:46:06 > 0:46:08And other places have messed my brain up.
0:46:08 > 0:46:13You've seen what I've come home from, I'm ten times worse.
0:46:13 > 0:46:16So...I don't know. I'd like to be able to see her.
0:46:16 > 0:46:21Yeah, see if she can do a Saturday, so I can take you, bring you back.
0:46:21 > 0:46:24Or we could just kidnap her and keep her downstairs.
0:46:26 > 0:46:27In Lincolnshire,
0:46:27 > 0:46:30James is taking high-strength vitamin B supplements.
0:46:31 > 0:46:37So, Rangan has put me on these pills.
0:46:37 > 0:46:40Rangan is hoping to cure James's chronic fatigue.
0:46:40 > 0:46:43- Yes, it has made a difference, hasn't it?- Oh, huge.
0:46:44 > 0:46:45It's, um...
0:46:45 > 0:46:49This isn't just in my mind, this is...this is massive.
0:46:49 > 0:46:51His symptoms are disappearing.
0:46:51 > 0:46:55I'm sleeping well, I'm waking up well,
0:46:55 > 0:46:58I'm feeling a lot better.
0:46:58 > 0:47:01I am staying awake throughout the day.
0:47:01 > 0:47:05But Rangan is surprised by the speed of his recovery.
0:47:05 > 0:47:07He retests James's blood
0:47:07 > 0:47:09and checks the results with leading professors
0:47:09 > 0:47:11in vitamin B and homocysteine.
0:47:11 > 0:47:18His homocysteine level was nearly 35, it was 34.53.
0:47:18 > 0:47:21I mean, that's one of the highest I've ever seen, actually.
0:47:21 > 0:47:26I gave him a supplement which contains B12 and folate,
0:47:26 > 0:47:32and...I never expected such a dramatic improvement.
0:47:38 > 0:47:41That's actually just come back, I'm just checking out.
0:47:41 > 0:47:43It's just come back,
0:47:43 > 0:47:46and his homocysteine has come back at seven now.
0:47:53 > 0:47:56Well, look, thank you very, very much for your time,
0:47:56 > 0:47:58and I will talk to you soon. Thank you.
0:48:01 > 0:48:03- Hi.- Hey, how are you doing?
0:48:03 > 0:48:05- It's good to see you. - Yeah, good to see you, too.
0:48:05 > 0:48:07How are you guys getting on?
0:48:07 > 0:48:09It really has snowballed.
0:48:09 > 0:48:13It's been an incredible transformation.
0:48:13 > 0:48:16Really, the changes have been happening almost daily
0:48:16 > 0:48:20and they are so profound, I can't ignore them.
0:48:20 > 0:48:23But I'm hoping to provide some answers for you.
0:48:23 > 0:48:24Why such a dramatic change?
0:48:24 > 0:48:27And so I've run some tests for you, OK,
0:48:27 > 0:48:29to try to work out what's been going on.
0:48:29 > 0:48:32So I did a genetic test
0:48:32 > 0:48:35for a particular pathway in your body, OK,
0:48:35 > 0:48:38that needs to function well for your body to function well.
0:48:38 > 0:48:41If that pathway is not working well in your body,
0:48:41 > 0:48:45- it can actually work up to 70% slower.- Right.
0:48:45 > 0:48:49So, if this car... This car is you, James, OK?
0:48:49 > 0:48:53And if you need to get to where you need to go,
0:48:53 > 0:48:56- ideally, if you are on a motorway, you'd be going at about 70mph.- Yeah.
0:48:56 > 0:49:00Right? You've got a genetic variation
0:49:00 > 0:49:02that means yours isn't going as fast.
0:49:02 > 0:49:05You are going, but you weren't function as well
0:49:05 > 0:49:08- as you could have been functioning. - Yeah.
0:49:08 > 0:49:12This makes sense, because there's, sort of, lots of things
0:49:12 > 0:49:15I've been able to do, just trundling along,
0:49:15 > 0:49:17but actually, as time has gone on,
0:49:17 > 0:49:21and there has been more pressure, there have been more places to be,
0:49:21 > 0:49:22there's been more need,
0:49:22 > 0:49:24there's been more requirement for me to be more alert,
0:49:24 > 0:49:27for me to be more on top of things, I can't deal with it.
0:49:27 > 0:49:30- That's it.- And I physically can't deal with it.
0:49:30 > 0:49:31The course of vitamin B
0:49:31 > 0:49:35has helped treat the genetic defect that was sapping James's energy.
0:49:35 > 0:49:39It's also reduced the chances of having a heart attack or stroke
0:49:39 > 0:49:42by lowering certain chemicals in his blood.
0:49:42 > 0:49:44The other thing is, your homocysteine,
0:49:44 > 0:49:46when I started, was 34.5.
0:49:46 > 0:49:47- Yeah.- That's very, very high.
0:49:47 > 0:49:49As I said, the highest I've ever seen.
0:49:49 > 0:49:51OK, it's now down to seven.
0:49:53 > 0:49:57- OK.- That's normal. That's what it should be, isn't it?- Yeah.
0:49:57 > 0:49:59It's a massive relief.
0:49:59 > 0:50:01HE LAUGHS
0:50:03 > 0:50:07- I felt like shit for 20 years. - LAUGHING:- Yeah.
0:50:08 > 0:50:13Something as simple as a B vitamin, essentially.
0:50:13 > 0:50:15Yes, a combination of supplements.
0:50:15 > 0:50:18- It's actually a really simple fix. - It's remarkable.
0:50:18 > 0:50:21I can't remember the last time I felt this well.
0:50:21 > 0:50:28I just wondered if I just couldn't cope...
0:50:30 > 0:50:32..with life, really.
0:50:42 > 0:50:43- Right. - Let's go, let's hit the beach.
0:50:43 > 0:50:46It's been a long time since we've been to the beach,
0:50:46 > 0:50:48and to be honest, last time, you actually took a photo
0:50:48 > 0:50:50when I fell asleep on the sand.
0:50:50 > 0:50:52- Yeah...- All right, let's go and do it without falling asleep.
0:50:56 > 0:50:57- This one?- Yeah..
0:50:57 > 0:50:59Right, one sec.
0:50:59 > 0:51:00Argh!
0:51:00 > 0:51:02What sort of differences have you noticed at home?
0:51:02 > 0:51:06- James isn't that tired any more. - He's not that tired any more?
0:51:06 > 0:51:07No.
0:51:07 > 0:51:11When we go to bed, he used to get really grumpy.
0:51:11 > 0:51:13But now he's a lot more playful.
0:51:13 > 0:51:18I really want him to stay non-grumpy.
0:51:18 > 0:51:20I'm still young.
0:51:20 > 0:51:23At least you haven't come, like, when I'm 20
0:51:23 > 0:51:26and he's, like, really old.
0:51:26 > 0:51:28James is...a different man.
0:51:28 > 0:51:30It's like being given a gift.
0:51:30 > 0:51:35Life has been such a hard toil lately, and, um...
0:51:35 > 0:51:41he's just filled with more positivity and vibrancy and energy.
0:51:41 > 0:51:44Anyone fancy a race to the pier? Hey?
0:51:47 > 0:51:50Right, guys, time for me to go.
0:51:50 > 0:51:53Thank you for everything. And...
0:51:56 > 0:51:58I hope we'll see you again.
0:51:58 > 0:52:00- Not for the same reasons, obviously. - LAUGHING:- Yeah!
0:52:00 > 0:52:02Thank you. Life-changing.
0:52:03 > 0:52:06I don't know what it feels like to have lost the last 20 years,
0:52:06 > 0:52:08in many ways.
0:52:08 > 0:52:10But I do know that, actually, this is the start for James.
0:52:10 > 0:52:14And actually, the next 20 years could be very, very different
0:52:14 > 0:52:15from the last 20 for this guy.
0:52:24 > 0:52:27Emma Gleeson has suffered from years of anxiety.
0:52:27 > 0:52:31She tried to suppress the feelings with alcohol, antidepressants
0:52:31 > 0:52:35and high-sugar foods that only made her symptoms worse.
0:52:37 > 0:52:39After two months with Emma and her family,
0:52:39 > 0:52:42Rangan is making one last house call.
0:52:42 > 0:52:45- What have you got in there? - I've got the beef bones -
0:52:45 > 0:52:47all you've got to do is give a little donation in the butchers
0:52:47 > 0:52:49and they just give you the beef bones.
0:52:49 > 0:52:52When I first asked for them, they thought they were for the dog.
0:52:52 > 0:52:54They were like, "Must be a big dog."
0:52:54 > 0:52:57I was like, "It's for me, cos I'm making stock.
0:52:57 > 0:52:58"I'm not a dog!"
0:52:58 > 0:53:03So I've got onions, head of garlic, parsnips, carrots,
0:53:03 > 0:53:06- rosemary, thyme, and loads of salt and pepper.- It looks amazing.
0:53:06 > 0:53:08So, Emma, when I first came to see you,
0:53:08 > 0:53:15you were drinking, you know, 60 to 70 units of alcohol a week.
0:53:15 > 0:53:16What are you having at the moment?
0:53:16 > 0:53:19I pretty much stuck to what I said I'd stick to,
0:53:19 > 0:53:24so, wine on a Friday and Saturday, nothing Sunday, Monday, Tuesday.
0:53:24 > 0:53:27I normally have one on Wednesday, nothing on a Thursday.
0:53:27 > 0:53:29When you say one, what, do you have a glass?
0:53:29 > 0:53:31Yes, I just buy the one-glass bottle.
0:53:31 > 0:53:34Because I don't need as much to drink any more.
0:53:34 > 0:53:37Yeah. It's about 15 units a week.
0:53:37 > 0:53:39So I'm nearly there.
0:53:39 > 0:53:40Hey!
0:53:40 > 0:53:46Look, compared to being nearly 70 units a week, 60 to 70 units,
0:53:46 > 0:53:51to go down to about 15 units a week, it's a massive reduction.
0:53:51 > 0:53:55You've seen Charlotte this week, haven't you? In person.
0:53:55 > 0:53:57Do you feel you do have a better understanding
0:53:57 > 0:54:00of, actually, how things have spiralled to this point?
0:54:00 > 0:54:05- Yeah.- And, potentially, how we may begin to un-spiral it?
0:54:05 > 0:54:07Yeah, yeah.
0:54:07 > 0:54:09When I went to meet her,
0:54:09 > 0:54:12I just thought, "She is possibly one of the only people
0:54:12 > 0:54:17"I would feel safe enough talking to about that kind of stuff."
0:54:17 > 0:54:20I think, once you've lived with anxiety and depression
0:54:20 > 0:54:24and all that stuff for so long, it's kind of hard to envisage...
0:54:24 > 0:54:26God, I've made myself cry.
0:54:26 > 0:54:29- But it's hard to imagine life without that.- Yeah.
0:54:29 > 0:54:32And letting it go is hard as well,
0:54:32 > 0:54:34cos, like, you're used to living like that.
0:54:36 > 0:54:40Can you imagine the possibility of life without this now?
0:54:40 > 0:54:41Yeah.
0:54:41 > 0:54:43I don't know why I'm crying.
0:54:43 > 0:54:44SHE LAUGHS
0:54:44 > 0:54:46It's a big deal, isn't it?
0:54:46 > 0:54:49- Sorry. - But it's a big deal.
0:54:49 > 0:54:52You've been living with this for so long,
0:54:52 > 0:54:56and I think you'd almost given up that, actually...
0:54:56 > 0:54:58What did you say to me?
0:54:58 > 0:55:01- "I'm too ill to fix." - Yeah, too broken to fix.
0:55:01 > 0:55:04Yeah. You're not too broken to fix.
0:55:04 > 0:55:06It doesn't mean it's easy,
0:55:06 > 0:55:08but you've started the process off now,
0:55:08 > 0:55:12you've started off the process to get yourself fixed.
0:55:12 > 0:55:13How's it going, all right?
0:55:16 > 0:55:20It's not only Rangan who's impressed with the change in Emma.
0:55:20 > 0:55:23I'm definitely proud of you cos that was one of the main things
0:55:23 > 0:55:26that I wanted you to change, was how much you did, like,
0:55:26 > 0:55:29how much alcohol you consumed within a space of a week.
0:55:29 > 0:55:32And I'm so glad you've cut down to how much you are having now,
0:55:32 > 0:55:34and it's definitely made me happy.
0:55:34 > 0:55:36- Thank you. - I'm very proud of you for it.
0:55:36 > 0:55:39Thank you. I'm proud of me, too.
0:55:39 > 0:55:42- You should be proud of yourself. - Yeah.
0:55:42 > 0:55:45Cool. Me and Marley are, like, awkward now.
0:55:45 > 0:55:47Where's your big speech? Come on.
0:55:47 > 0:55:50LAUGHTER
0:55:53 > 0:55:57You've done amazingly well, you really have.
0:55:57 > 0:56:01And...it's been amazing for me to be part of that journey with you
0:56:01 > 0:56:04and, um, keep up, it's just the start, it really is.
0:56:04 > 0:56:06Have I made you cry now?
0:56:06 > 0:56:09LAUGHTER
0:56:09 > 0:56:10Thank you so much.
0:56:10 > 0:56:14- It's just emotional. - Why are you looking at me?
0:56:14 > 0:56:17- I mean it, thank you.- Yeah.
0:56:17 > 0:56:19Yeah, thanks very much. Thanks, Rangan.
0:56:19 > 0:56:22It's good jamming with you, and good that you sorted Emma.
0:56:22 > 0:56:25We're getting there, she's on the right road, I think.
0:56:25 > 0:56:27It's a long process, but, yeah.
0:56:27 > 0:56:32'Something has changed, something has really changed in Emma.
0:56:33 > 0:56:37'She's got this strength, she's got the resolve now,
0:56:37 > 0:56:40'she can contemplate seeing a therapist now.'
0:56:40 > 0:56:44This is a lady now who's got control of where her life goes.
0:56:44 > 0:56:48She doesn't have to be a slave to her illness,
0:56:48 > 0:56:50she can actually be its master.
0:56:50 > 0:56:52It's fantastic to see.
0:56:52 > 0:56:55I think the future looks really, really bright for Emma.
0:56:56 > 0:57:01Next time, Rangan travels to London to help an 11-year-old schoolboy...
0:57:01 > 0:57:03Get those hips moving, Mum.
0:57:03 > 0:57:06..mystified by his weight problems...
0:57:06 > 0:57:08It's about 11st 1lb.
0:57:08 > 0:57:10That's how much I weigh.
0:57:11 > 0:57:15..and tries to help a teenager overcome an eating disorder.
0:57:15 > 0:57:17Do you think there was "before food" time?
0:57:17 > 0:57:21- What's up?- I'm just anxious about food, that's all.
0:57:21 > 0:57:23She's not really trying to tackle this,
0:57:23 > 0:57:25and I don't want to botch this up.
0:57:25 > 0:57:27I really don't want to mess it up.