Episode 4

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0:00:02 > 0:00:03This man's had a previous stroke,

0:00:03 > 0:00:08which makes things a bit more complicated in assessing him.

0:00:08 > 0:00:09In - one, two, three.

0:00:09 > 0:00:11Out - one, two, three.

0:00:11 > 0:00:12Cough, come on, cough.

0:00:12 > 0:00:14HE COUGHS

0:00:14 > 0:00:16I think you brought it up.

0:00:16 > 0:00:19It all started with a pea size

0:00:19 > 0:00:21that lived in my right sinus.

0:00:21 > 0:00:23Then it began to grow

0:00:23 > 0:00:26and it came out almost like half a golf ball on my face.

0:00:28 > 0:00:30'You get trained on how to break bad news...'

0:00:30 > 0:00:32We're in to do the bloods, is that OK?

0:00:32 > 0:00:34'..but sometimes you find yourself getting too close to patients,

0:00:34 > 0:00:37'so it's is about finding that balance.'

0:00:37 > 0:00:39Fat grafting is actually pretty simple.

0:00:39 > 0:00:42This is how we harvest it, with this cannula,

0:00:42 > 0:00:47so we're going to start now and harvest some fat.

0:00:47 > 0:00:50There is a risk of bleeding in your brain.

0:00:50 > 0:00:52- Are you able to understand that? - Help.

0:00:53 > 0:00:56Can we try to get a relative on the phone?

0:01:08 > 0:01:11We've spent a year looking under the skin of the Health Service,

0:01:11 > 0:01:13focusing on the large team of people

0:01:13 > 0:01:16who dedicate their lives to saving ours.

0:01:19 > 0:01:21In the Royal Victoria Hospital,

0:01:21 > 0:01:25Doctor Enda Kerr is treating 67-year-old James McCabe,

0:01:25 > 0:01:28who he suspects has had a stroke.

0:01:28 > 0:01:30My name is Doctor Kerr,

0:01:30 > 0:01:32one of the doctors from the stroke unit.

0:01:32 > 0:01:35This is Maria Kinnaird, our stroke specialist nurse.

0:01:35 > 0:01:37All right, pet?

0:01:37 > 0:01:40T-t-t...

0:01:40 > 0:01:41HE WAILS

0:01:41 > 0:01:43Are you able to lift your arm up?

0:01:45 > 0:01:47Good. Can you keep it up?

0:01:47 > 0:01:48Keep it up for ten seconds.

0:01:48 > 0:01:52Ten, nine, eight, seven,

0:01:52 > 0:01:56six, five, four,

0:01:56 > 0:01:58three, two... Right.

0:01:59 > 0:02:01That is a typical drift.

0:02:01 > 0:02:03Can we try to get a relative on the phone

0:02:03 > 0:02:06to establish what his baseline language was like?

0:02:08 > 0:02:11Mr McCabe, he was already in the hospital,

0:02:11 > 0:02:13he was having a procedure done on his heart

0:02:13 > 0:02:17called a coronary angiogram, or a dye test of his arteries, and...

0:02:17 > 0:02:20not an uncommon complication of that procedure

0:02:20 > 0:02:22would be to develop a small clot

0:02:22 > 0:02:23to go up into the brain

0:02:23 > 0:02:25and present as having a stroke.

0:02:25 > 0:02:28Try to point to the ceiling with your finger.

0:02:33 > 0:02:35Is that...?

0:02:36 > 0:02:39It's hard to understand that one, is it? OK.

0:02:39 > 0:02:41We talk about time as brain,

0:02:41 > 0:02:43the quicker you get to us,

0:02:43 > 0:02:45the quicker we give you the treatment,

0:02:45 > 0:02:46the more likely it's going to be effective

0:02:46 > 0:02:49and, really, you need to get to us within three or four hours.

0:02:49 > 0:02:52We're literally talking about a five to ten-minute assessment

0:02:52 > 0:02:54of the patient to clarify the diagnosis.

0:02:54 > 0:02:55Have any double vision?

0:02:55 > 0:02:57'Figure out how bad the stroke is

0:02:57 > 0:02:59'and then get them urgently to the CT scanner.'

0:02:59 > 0:03:01Don't worry.

0:03:01 > 0:03:05James is showing some of the symptoms associated with a stroke

0:03:05 > 0:03:08but, as he was already in hospital when it began,

0:03:08 > 0:03:10time should hopefully be on his side.

0:03:10 > 0:03:12Are you able to lift that leg at all? Not at all.

0:03:17 > 0:03:21While most of us will only need the care and support of the NHS

0:03:21 > 0:03:23a few times in our lives,

0:03:23 > 0:03:25there are some who will need much more.

0:03:26 > 0:03:28Well, Grace has been coming to the School of Dentistry

0:03:28 > 0:03:31for probably about ten years now

0:03:31 > 0:03:34and has had a variety of treatments done over the years.

0:03:34 > 0:03:36Grace Smith was a keen socialite

0:03:36 > 0:03:39and captain of the local golf club.

0:03:39 > 0:03:41At the age of 46,

0:03:41 > 0:03:42she was struck by cancer.

0:03:43 > 0:03:48It all really started with a pea size

0:03:48 > 0:03:50that lived in my right sinus,

0:03:50 > 0:03:53then it began to grow and it came out

0:03:53 > 0:03:55almost like half a golf ball on my face.

0:03:58 > 0:04:01Grace had an aggressive cancer of the salivary glands.

0:04:01 > 0:04:03She has had to have her upper jaw bone,

0:04:03 > 0:04:05lower eye socket

0:04:05 > 0:04:07and most of the right side of her face removed.

0:04:07 > 0:04:09Over the last 12 years,

0:04:09 > 0:04:12a team of experts have used the latest pioneering technology

0:04:12 > 0:04:15to gradually reconstruct her face.

0:04:16 > 0:04:20I had three very young children at the time.

0:04:20 > 0:04:21I knew that I had no alternative.

0:04:21 > 0:04:23I had to go through with it

0:04:23 > 0:04:25or I wasn't going to be here.

0:04:25 > 0:04:28That was really how I felt.

0:04:28 > 0:04:30Anything I had...

0:04:30 > 0:04:33thought of doing or any plans that I had made

0:04:33 > 0:04:36really all just...

0:04:36 > 0:04:37disappeared

0:04:37 > 0:04:39cos nothing matters any more

0:04:39 > 0:04:41and your main thought is,

0:04:41 > 0:04:45"I have cancer and I have to fight it, and I have to get through."

0:04:45 > 0:04:48I would say, in my own small way,

0:04:48 > 0:04:50I was maybe a little vain in life.

0:04:50 > 0:04:53I wouldn't have gone to work without my make-up on

0:04:53 > 0:04:56and I wouldn't have gone out without make-up and nails done,

0:04:56 > 0:04:58so it really hit hard.

0:04:58 > 0:05:00It hit home very hard that,

0:05:00 > 0:05:01all of a sudden,

0:05:01 > 0:05:03I'd gone from being

0:05:03 > 0:05:05a bubbly, outward-looking person

0:05:05 > 0:05:09to living life behind dark glasses

0:05:09 > 0:05:11for 11, 12 years.

0:05:13 > 0:05:14Scalpel blade.

0:05:16 > 0:05:19I'm just going to cut away a wee bit of this as well.

0:05:19 > 0:05:21Grace lost all of her top teeth and upper jaw bone

0:05:21 > 0:05:24as a result of the cancer.

0:05:24 > 0:05:27But today, specialist dental surgeon Dr Simon Killough

0:05:27 > 0:05:30is taking a mould of her reconstructed hard palate

0:05:30 > 0:05:33so she can be fitted for a permanent bridge.

0:05:33 > 0:05:35Really, to get the teeth back in

0:05:35 > 0:05:37will restore her...

0:05:37 > 0:05:39cosmetic appearance, first of all,

0:05:39 > 0:05:42and then also her function.

0:05:42 > 0:05:46She'll be able to eat and drink much more easily.

0:05:46 > 0:05:50The teeth and the smile is such an important part of who we are

0:05:50 > 0:05:54and that's one of the aspects of head and neck cancer,

0:05:54 > 0:05:55it can take that away.

0:05:55 > 0:05:58And it is such a nice part of the job

0:05:58 > 0:06:00to be able to give that back to the patient,

0:06:00 > 0:06:02to give them back their smile.

0:06:03 > 0:06:06Can't smile really without upper teeth,

0:06:06 > 0:06:08so I'm really looking forward

0:06:08 > 0:06:09to being able to smile.

0:06:09 > 0:06:12Also, I have a granddaughter

0:06:12 > 0:06:15and I can't give her a kiss on the cheek

0:06:15 > 0:06:18because I can't do the kissing

0:06:18 > 0:06:20formation with no teeth.

0:06:22 > 0:06:25It's taken 14 surgeries over 12 years

0:06:25 > 0:06:28to get Grace to where she is today -

0:06:28 > 0:06:32the most complex of which was to replace her entire upper jaw bone.

0:06:34 > 0:06:35In 2014,

0:06:35 > 0:06:37a team of surgeons at the Ulster Hospital

0:06:37 > 0:06:41were able to make use of some cutting-edge technology,

0:06:41 > 0:06:43recently pioneered in Belgium,

0:06:43 > 0:06:47which allowed them to make a precise 3-D representation

0:06:47 > 0:06:49of Grace's original jawbone.

0:06:49 > 0:06:51They then replicated it

0:06:51 > 0:06:53using the fibula from her leg.

0:06:54 > 0:06:57The main difficulties with this reconstruction -

0:06:57 > 0:06:59the fibula bone is used routinely here and elsewhere

0:06:59 > 0:07:02to reconstruct the lower jawbone,

0:07:02 > 0:07:03quite a straight bone in a way,

0:07:03 > 0:07:06but trying to do that with the upper jawbone,

0:07:06 > 0:07:08the maxilla, is much more complex

0:07:08 > 0:07:12and that's where the 3-D planning technology came into play.

0:07:12 > 0:07:16It basically uses the image data on the CT scans

0:07:16 > 0:07:18and you can do the virtual surgical planning,

0:07:18 > 0:07:21pre-plan where you're going to cut the bone,

0:07:21 > 0:07:23and generate a template like this.

0:07:24 > 0:07:26These slots are all appropriately angled

0:07:26 > 0:07:28so that, when you make all those cuts,

0:07:28 > 0:07:30it will all piece together

0:07:30 > 0:07:32in a jigsaw fashion, like that.

0:07:32 > 0:07:34It was very, very precise

0:07:34 > 0:07:36and there's no wastage at all

0:07:36 > 0:07:38because you know exactly

0:07:38 > 0:07:40at what millimetre you have to cut.

0:07:40 > 0:07:42While in the old days, if you wanted to do something similar,

0:07:42 > 0:07:46you'd be guessing that, "I need this to be 7-8 millimetres,

0:07:46 > 0:07:47"I need this to be that angle,"

0:07:47 > 0:07:49and if it doesn't fit, you have to trim a bit.

0:07:52 > 0:07:55The Macmillan Unit is located in the grounds of Antrim Area Hospital.

0:07:55 > 0:07:58It's a specialist palliative care facility

0:07:58 > 0:08:01for those in the advanced stages of progressive illnesses,

0:08:01 > 0:08:05such as cancer, motor neurone disease and heart failure.

0:08:07 > 0:08:1123-year-old junior doctor Conal Corr begins his rounds.

0:08:11 > 0:08:13I'm currently a foundation year one doctor.

0:08:13 > 0:08:16My first rotation is up here, in the Macmillan Unit,

0:08:16 > 0:08:19to start off my first job as a doctor.

0:08:20 > 0:08:21- Hello, Maureen.- Hello.

0:08:21 > 0:08:24- How are you?- Not so bad.

0:08:24 > 0:08:25Are you OK sitting forward?

0:08:25 > 0:08:27You're not sore or anything, are you?

0:08:27 > 0:08:31- My stethoscope might be a wee bit cold, all right?- That's all right.

0:08:31 > 0:08:34Maureen was a really, really fit and healthy individual.

0:08:34 > 0:08:37She was a horse riding trainer

0:08:37 > 0:08:39and a gymnast,

0:08:39 > 0:08:42and I think that's why she's managed to get to the age that she is

0:08:42 > 0:08:44without any problems.

0:08:44 > 0:08:48And I think that's why the cancer that she does have

0:08:48 > 0:08:51has been allowed to grow and to spread

0:08:51 > 0:08:54without her really noticing it until a very late stage, unfortunately.

0:08:54 > 0:08:56That's you, all right?

0:08:56 > 0:08:57SHE COUGHS

0:08:57 > 0:09:00- Is that cough still bothering you, is it?- No, it's not bothering me.

0:09:00 > 0:09:02- Are you sure now? Are you just being a trooper?- No, no.

0:09:02 > 0:09:03THEY LAUGH

0:09:03 > 0:09:05I'll leave you in peace now, anyway.

0:09:05 > 0:09:08- All right?- Thank you very much. - See you soon.

0:09:12 > 0:09:13You have to be a people person.

0:09:13 > 0:09:15You have to be able to talk to people.

0:09:15 > 0:09:16There has to be a relationship.

0:09:16 > 0:09:19And I think that's why I'm interested in palliative care

0:09:19 > 0:09:20and end of life care,

0:09:20 > 0:09:22because there's so much...

0:09:22 > 0:09:23It's SO patient-centred.

0:09:25 > 0:09:26The nurses are brilliant.

0:09:26 > 0:09:29Really, really lovely, lovely nurses -

0:09:29 > 0:09:31every one of them.

0:09:31 > 0:09:34Doctors, everything, staff, the lot.

0:09:34 > 0:09:36Could not get better.

0:09:38 > 0:09:41I have a few, like, non-medical friends,

0:09:41 > 0:09:42and when I started the job,

0:09:42 > 0:09:44I was maybe a month or two in,

0:09:44 > 0:09:47and they'd have said, "Oh, Conal, how many lives have you saved?"

0:09:47 > 0:09:49I sort of said, "Well, none,

0:09:49 > 0:09:51"because I don't work in that setting."

0:09:51 > 0:09:53But psychologically

0:09:53 > 0:09:55that's difficult because you're not actually treating people.

0:09:55 > 0:09:58You're not able to fix things and that has been challenging.

0:09:58 > 0:10:00But, apart from that, I love it.

0:10:00 > 0:10:02I couldn't see myself in any other career.

0:10:08 > 0:10:09In Lurgan hospital,

0:10:09 > 0:10:13the Acute Care at Home Team are having their morning meeting.

0:10:13 > 0:10:15Gentleman came on Friday evening,

0:10:15 > 0:10:17MS man, he's in bed at the minute.

0:10:17 > 0:10:20He remained quite chesty over the weekend.

0:10:20 > 0:10:22What fluids is he having, Ann?

0:10:22 > 0:10:24'This is a very unique team.'

0:10:24 > 0:10:26We're the first team within Northern Ireland

0:10:26 > 0:10:29to actually act within this model.

0:10:29 > 0:10:31You'll hopefully see him this afternoon.

0:10:31 > 0:10:33Paul will start cough assist

0:10:33 > 0:10:34and whatever nurse...

0:10:34 > 0:10:37If you can do a joint visit with the nurse this afternoon.

0:10:37 > 0:10:40So, it's a multidisciplinary team

0:10:40 > 0:10:42made up of specialist nurses, physio,

0:10:42 > 0:10:45pharmacist and our consultant doctors.

0:10:45 > 0:10:47It's hospital at home.

0:10:47 > 0:10:50We're doing all the care and intervention that a hospital can do.

0:10:53 > 0:10:56The idea of our service is to cut out hospital admission,

0:10:56 > 0:10:58where they'll be treated within the home.

0:10:58 > 0:11:00Maybe a doctor has been called out,

0:11:00 > 0:11:02our team will come into play

0:11:02 > 0:11:05and we will go and see them and see if they are appropriate

0:11:05 > 0:11:06for the Acute Care at Home Team.

0:11:08 > 0:11:12The acute care service also has big benefits for patients,

0:11:12 > 0:11:15who can be treated in the comfort of their own homes,

0:11:15 > 0:11:16and their families,

0:11:16 > 0:11:21who can avoid the hassle and expense of repeated hospital visits.

0:11:21 > 0:11:23Anne Graham's husband, Billy, has MS...

0:11:23 > 0:11:25Hello, Anne. Hello.

0:11:25 > 0:11:27..and was referred to the team last week

0:11:27 > 0:11:29as he's currently suffering from pneumonia.

0:11:29 > 0:11:32We'll explain everything to you.

0:11:32 > 0:11:34Take a nice, deep breath when you're ready again.

0:11:34 > 0:11:36- Go, a big one. - HE EXHALES

0:11:38 > 0:11:40BILLY COUGHS

0:11:40 > 0:11:42That's OK. That's OK.

0:11:42 > 0:11:43The team that come out

0:11:43 > 0:11:45are really, really good.

0:11:45 > 0:11:48And there is a nurse comes three times a day,

0:11:48 > 0:11:52and does all the injections and things.

0:11:52 > 0:11:54Breathe in with the machine.

0:11:54 > 0:11:57In - one, two, three. Rest.

0:11:57 > 0:11:59It's great because

0:11:59 > 0:12:01you don't have to be tied to a time

0:12:01 > 0:12:02to go and see him,

0:12:02 > 0:12:04you can see him at any time,

0:12:04 > 0:12:07and you know what's going on all the time,

0:12:07 > 0:12:11instead of going into the hospital and being told.

0:12:11 > 0:12:13You know at the time what's happening.

0:12:13 > 0:12:15It's much better, so it is.

0:12:15 > 0:12:17In - one, two, three.

0:12:17 > 0:12:19Out - one, two, three.

0:12:19 > 0:12:21In - one, two, three. Cough.

0:12:21 > 0:12:22Come on, cough.

0:12:22 > 0:12:24- HE COUGHS - Very good. Very good.

0:12:24 > 0:12:26'Cough assist is one of the best options

0:12:26 > 0:12:28'to help him clear the secretions.'

0:12:28 > 0:12:30Clearing secretions are going to help improve the infection

0:12:30 > 0:12:33- as early as possible. - HE COUGHS

0:12:33 > 0:12:34Good, strong cough there.

0:12:34 > 0:12:36Well done.

0:12:36 > 0:12:38He's quite well this afternoon.

0:12:38 > 0:12:42He will still need quite a few more days of intensive physio

0:12:42 > 0:12:43and intravenous antibiotics.

0:12:43 > 0:12:45We'll also be taking blood samples

0:12:45 > 0:12:48to check the effectiveness of the treatment.

0:12:48 > 0:12:50Well done. Well done.

0:12:50 > 0:12:52We could take most of our pneumonias back into the home

0:12:52 > 0:12:55and we could look after them if we have a good team down.

0:12:55 > 0:12:57Most of the pneumonias can be looked after at home.

0:12:57 > 0:12:59You don't really need hospital admission,

0:12:59 > 0:13:02unless they are critically unwell.

0:13:02 > 0:13:04I haven't been well myself,

0:13:04 > 0:13:06which means I can't drive all the time.

0:13:06 > 0:13:10I couldn't get down to see him if he was in hospital.

0:13:10 > 0:13:13At least, if I have him at home, I can see what's going on.

0:13:13 > 0:13:15It's great.

0:13:15 > 0:13:18They even come out here to the house...

0:13:18 > 0:13:20instead of having me go into hospital,

0:13:20 > 0:13:23in which they are more packed.

0:13:23 > 0:13:24Better for them to come here.

0:13:27 > 0:13:29At Craigavon Area Hospital,

0:13:29 > 0:13:31their always-busy laundry department

0:13:31 > 0:13:33has become a integral part

0:13:33 > 0:13:36of the Southern Trust's domestic services,

0:13:36 > 0:13:38with the staff here managing the laundry

0:13:38 > 0:13:40for eight separate hospitals.

0:13:40 > 0:13:43It opened back in 1972

0:13:43 > 0:13:45and head of linen services, Anne Forbes,

0:13:45 > 0:13:48has been at the helm for the past 15 years.

0:13:48 > 0:13:52That's the Belfast linen being sent out.

0:13:52 > 0:13:54Going out, yeah.

0:13:54 > 0:13:57In this laundry, we employ 52 staff.

0:13:57 > 0:14:01We process about 100,000 pieces of linen a week

0:14:01 > 0:14:05and we service up to 1,600 beds.

0:14:07 > 0:14:09All the linen that comes within the health service

0:14:09 > 0:14:12must be washed at a thermal disinfection temperature

0:14:12 > 0:14:17and that's to ensure that all infections are destroyed

0:14:17 > 0:14:20and the linen is safe, at point of use, for the patient.

0:14:22 > 0:14:24Every delivery of dirty laundry

0:14:24 > 0:14:26must first pass through the sorting room,

0:14:26 > 0:14:28where the team takes special care

0:14:28 > 0:14:30to ensure that no unwanted items

0:14:30 > 0:14:32end up in the wash.

0:14:32 > 0:14:36We get phone calls here to watch out for mobile phones

0:14:36 > 0:14:37and iPods,

0:14:37 > 0:14:39false teeth...

0:14:39 > 0:14:41You're never surprised what you're going to find

0:14:41 > 0:14:44when you open a bag in here, you know? It could be anything.

0:14:44 > 0:14:47The only thing we haven't found is a patient.

0:14:47 > 0:14:50There's times that there's stuff comes in here

0:14:50 > 0:14:52and the smell is overpowering.

0:14:52 > 0:14:55You have to have a really, really strong stomach sometimes, you know?

0:14:55 > 0:14:57But you get used to it in the end, you know.

0:15:03 > 0:15:05Back at the Royal, it's 30 minutes

0:15:05 > 0:15:08since James McCabe's started showing signs of a stroke

0:15:08 > 0:15:11and the team are ready to begin his CT scan.

0:15:13 > 0:15:16We want to see if we can identify any large arteries that are blocked,

0:15:16 > 0:15:18in this man's brain,

0:15:18 > 0:15:20that seem to be causing this sudden speech problem

0:15:20 > 0:15:24and visual problem that he's developed.

0:15:24 > 0:15:25But as the results start coming in,

0:15:25 > 0:15:29a diagnosis could prove trickier than expected.

0:15:29 > 0:15:32This is complicated cos this man's had a previous stroke

0:15:32 > 0:15:33in the right side of his brain,

0:15:33 > 0:15:36causing left-sided weakness,

0:15:36 > 0:15:38which makes things a bit more complicated in assessing him.

0:15:38 > 0:15:40A major riddle...

0:15:40 > 0:15:42'The most exciting treatments

0:15:42 > 0:15:44'that people talk about for acute stroke are...'

0:15:44 > 0:15:47One is an intravenous drug, that we call thrombolysis,

0:15:47 > 0:15:49that helps to dissolve clots.

0:15:49 > 0:15:52There's some risk, with that drug, of causing bleeding -

0:15:52 > 0:15:55so selecting a patient for that treatment is really important.

0:15:55 > 0:15:59The second real major advance in stroke treatment in recent years

0:15:59 > 0:16:01is a thing called clot retrieval,

0:16:01 > 0:16:03where we have colleagues in our hospital here

0:16:03 > 0:16:07who can go into your arteries, in your brain, with little fine tubes,

0:16:07 > 0:16:10find the clot and physically pull it out.

0:16:10 > 0:16:13It's remarkable when you see someone with a dense stroke

0:16:13 > 0:16:15going from unable to speak, unable to move, to -

0:16:15 > 0:16:17within minutes or hours after that treatment -

0:16:17 > 0:16:19standing up and walking out.

0:16:21 > 0:16:22We're trying to figure out

0:16:22 > 0:16:25whether you've had a stroke or not this morning.

0:16:25 > 0:16:27Another stroke.

0:16:27 > 0:16:28OK?

0:16:28 > 0:16:31You're large arteries in your brain are OK.

0:16:32 > 0:16:35It might be that there's a small artery in your brain

0:16:35 > 0:16:39that's blocked by a clot.

0:16:39 > 0:16:41The treatment for that is a clot-busting drug

0:16:41 > 0:16:43that we call thrombolysis,

0:16:43 > 0:16:46but there is some risk with doing that,

0:16:46 > 0:16:48in giving you that treatments.

0:16:49 > 0:16:51It's about one in 50,

0:16:51 > 0:16:542% risk,

0:16:54 > 0:16:56of bleeding in your brain.

0:16:56 > 0:16:58That could make you worse.

0:16:58 > 0:17:00Do you understand that?

0:17:00 > 0:17:02Are you able to understand that?

0:17:02 > 0:17:03Help.

0:17:05 > 0:17:07OK. Oh, it's frustrating,

0:17:07 > 0:17:08it is frustrating.

0:17:08 > 0:17:10OK.

0:17:10 > 0:17:14I think what we'll do is we'll give him thrombolysis.

0:17:14 > 0:17:16I can't exclude that he's not had a stroke

0:17:16 > 0:17:18- and he has severe speech problems.- OK.

0:17:22 > 0:17:25OK, sir, I'm going to give this clot-busting medication now, OK?

0:17:27 > 0:17:28I have some suspicion

0:17:28 > 0:17:31that there may be something else going on other than a stroke

0:17:31 > 0:17:34but, at the moment, it's impossible to tell for sure

0:17:34 > 0:17:36whether it was or was not a stroke.

0:17:36 > 0:17:38I'm just going to flush through a bit of water.

0:17:38 > 0:17:42The scans are good, there's no major artery occlusion,

0:17:42 > 0:17:45so this thing seemed to happen very suddenly.

0:17:45 > 0:17:46It is in keeping with a stroke

0:17:46 > 0:17:49and he seems to have right-sided weakness

0:17:49 > 0:17:50along with a loss of language,

0:17:50 > 0:17:52which is very much in keeping with a stroke.

0:17:52 > 0:17:54Just the way he's behaving.

0:17:54 > 0:17:55He seems a bit frustrated with it

0:17:55 > 0:17:58and that's making me wonder, you know, for sure.

0:17:58 > 0:18:01But, if it is a stroke, then we only one option

0:18:01 > 0:18:03and the option is to get rid of this clot

0:18:03 > 0:18:05and the only way we can do that now

0:18:05 > 0:18:07is by giving him the clot-busting drug.

0:18:08 > 0:18:12Tough calls like these are part of everyday life for doctors.

0:18:12 > 0:18:15Mr McCabe will be kept under close observation

0:18:15 > 0:18:17to see how he responds to the treatment.

0:18:22 > 0:18:23At the Ulster Hospital,

0:18:23 > 0:18:25cancer survivor Grace Smith

0:18:25 > 0:18:27is in for yet another operation.

0:18:27 > 0:18:31Plastic surgeons Chris Hill and Declan Lannon

0:18:31 > 0:18:33want to close a hole in her upper palate

0:18:33 > 0:18:35as well as taking fat from her stomach

0:18:35 > 0:18:38to help rebuild her face.

0:18:38 > 0:18:41Grace, I haven't seen you since we did the last fat grafting,

0:18:41 > 0:18:44so I know that your tummy was quite sore afterwards

0:18:44 > 0:18:48and I'm afraid it probably will be again but,

0:18:48 > 0:18:50just looking, it has added a bit more volume in here,

0:18:50 > 0:18:53but there's still this contour deformity in your cheek

0:18:53 > 0:18:55and we'll really aim to try and fill that out this time.

0:18:57 > 0:19:00..but despite undergoing numerous surgeries,

0:19:00 > 0:19:03it still doesn't get any easier for Grace.

0:19:03 > 0:19:05Apprehensive, nervous,

0:19:05 > 0:19:07but I'm in the very best of hands.

0:19:07 > 0:19:09So, looking forward to getting another stage

0:19:09 > 0:19:13in the journey completed and one more move towards the end.

0:19:19 > 0:19:21There are two parts to today's procedure.

0:19:21 > 0:19:23We're going to do some fat grafting to her cheek

0:19:23 > 0:19:25and we're going to then try to close

0:19:25 > 0:19:28the palatial fistula in her mouth.

0:19:28 > 0:19:31What I'm doing now is I'm just looking at her face,

0:19:31 > 0:19:32at the side that's unaffected,

0:19:32 > 0:19:34and I'm just trying to decide...

0:19:34 > 0:19:36We're looking at the contours here on the right side

0:19:36 > 0:19:41to decide where I'm going to put the most fat.

0:19:41 > 0:19:44The sorest bit of the fat grafting procedure is her abdomen.

0:19:44 > 0:19:46It will feel a bit...

0:19:46 > 0:19:50I tell patients it feels a bit like being punched in the tummy,

0:19:50 > 0:19:53so it's not agony, but it's still uncomfortable.

0:19:55 > 0:19:58Fat grafting is actually pretty simple.

0:19:58 > 0:19:59This is how we harvest it,

0:19:59 > 0:20:01with this cannula.

0:20:01 > 0:20:02When it sucks the fat in,

0:20:02 > 0:20:05the idea is to try and not damage the fat

0:20:05 > 0:20:06cos we want the fat to be viable

0:20:06 > 0:20:09so that it will survive when we transfer it to her face.

0:20:09 > 0:20:13So, we're going to start now and harvest some fat.

0:20:13 > 0:20:15So, I'm just making a little stab incision

0:20:15 > 0:20:18through the skin into the fat here

0:20:18 > 0:20:20and then, that's now sitting in the subcutaneous fat.

0:20:20 > 0:20:23I can feel where the tip of the cannula is

0:20:23 > 0:20:24and I've got the suction now on this

0:20:24 > 0:20:28and you can see the fat starting to come into the syringe.

0:20:28 > 0:20:31It'll be quite watery because of the local anaesthetic.

0:20:31 > 0:20:33It's a bit repetitive, but...

0:20:33 > 0:20:37it's fine when we're not trying to harvest too many syringes,

0:20:37 > 0:20:40but, if you're harvesting 20 or 30 ten-mil syringes,

0:20:40 > 0:20:43it becomes quite hard work.

0:20:43 > 0:20:46So, you can see that's a syringe of harvested fat.

0:20:48 > 0:20:51Once Mr Hill has harvested a sufficient amount of fat,

0:20:51 > 0:20:54it then has to be centrifuged and separated

0:20:54 > 0:20:56before being re-injected into her face.

0:20:56 > 0:20:58OK.

0:20:58 > 0:20:59The centrifuge has stopped

0:20:59 > 0:21:01and we're just going to lift these out...

0:21:01 > 0:21:02You grab the other two, Chris.

0:21:02 > 0:21:05..and you can see, it's quite colourful, actually.

0:21:05 > 0:21:07This is the fluid layer, with the blood.

0:21:07 > 0:21:09There's a little patch at the bottom.

0:21:09 > 0:21:12This is the viable fat and, at the top, you can see the oil.

0:21:12 > 0:21:14Now, clearly here, you need to be careful

0:21:14 > 0:21:17that the fat doesn't actually start to run out.

0:21:17 > 0:21:19It's, sort of, held in by the suction at the minute,

0:21:19 > 0:21:21but it will fall out, eventually.

0:21:21 > 0:21:24And that is the fat that we're going to use.

0:21:24 > 0:21:25And that's it...clean now.

0:21:27 > 0:21:29Just let it slide back down the tube.

0:21:31 > 0:21:33So, we're going to infiltrate the fat now with this.

0:21:33 > 0:21:35This is a blunt cannula,

0:21:35 > 0:21:38so through this tiny, little incision

0:21:38 > 0:21:40I'm just going to advance this cannula under the skin.

0:21:40 > 0:21:43You can see it moving down.

0:21:43 > 0:21:45Now, the idea is to infiltrate the fat

0:21:45 > 0:21:47as you withdraw and you can see, look.

0:21:47 > 0:21:51You can see the little ridge of fat that's been left behind.

0:21:51 > 0:21:54So, you just keep doing that until the area is filled.

0:21:55 > 0:21:57Each layer of fat that's placed

0:21:57 > 0:21:59will be close to her blood supply.

0:21:59 > 0:22:00If you put it all in the same place,

0:22:00 > 0:22:02if you just keep injecting and blow one area up,

0:22:02 > 0:22:04the innermost layer of fat,

0:22:04 > 0:22:05or the inner layers of fat,

0:22:05 > 0:22:08will be too far from the blood supply to actually take as a graft.

0:22:10 > 0:22:12After about four months,

0:22:12 > 0:22:13the fat is felt to be stable,

0:22:13 > 0:22:16so the patient, the volume that they gain

0:22:16 > 0:22:19will remain and really will remain indefinitely.

0:22:19 > 0:22:21So, it's a permanent fix

0:22:21 > 0:22:24and we've certainly significantly improved the contour.

0:22:24 > 0:22:28This fat grafting is only the first part of today's surgery -

0:22:28 > 0:22:31Grace lost most of her upper palate due to the cancer -

0:22:31 > 0:22:33but after this dual operation,

0:22:33 > 0:22:36it should be restored to normal function.

0:22:36 > 0:22:37This lady has a large fistula,

0:22:37 > 0:22:39a large hole in the roof of her mouth,

0:22:39 > 0:22:43connecting into what would have been her sinus and her nose,

0:22:43 > 0:22:45her nasal cavity.

0:22:45 > 0:22:47So, that's giving her nasal speech

0:22:47 > 0:22:50and it can cause a certain amount of nasal regurgitation,

0:22:50 > 0:22:53where food and fluid can pour out of the nose.

0:22:53 > 0:22:55We're trying to close that.

0:22:55 > 0:22:57Declan has raised this oral flap

0:22:57 > 0:23:00and it's going to swing back the way

0:23:00 > 0:23:02and stitch across that, like that.

0:23:02 > 0:23:04We'll be using the front of her palate

0:23:04 > 0:23:07to try to close the back of the palate.

0:23:07 > 0:23:09The front of her palate will then be a raw area.

0:23:09 > 0:23:11It will be a raw, unclosed wound

0:23:11 > 0:23:15that will have to heal itself over the coming weeks.

0:23:21 > 0:23:23Back at the Macmillan Unit...

0:23:23 > 0:23:26We need a blood sample on Jacqueline in room 12.

0:23:26 > 0:23:29..junior doctor Conal Corr is finishing his rounds.

0:23:29 > 0:23:32Unfortunately, it has been tried a few times

0:23:32 > 0:23:34and it's been really difficult to get it,

0:23:34 > 0:23:37so we're going to have another go on her, just to see.

0:23:37 > 0:23:39I will have two goes. Two goes is quite reasonable.

0:23:39 > 0:23:40Three's pushing it.

0:23:43 > 0:23:46Then you might want to just refer on to somebody else who can do it,

0:23:46 > 0:23:47who's maybe more experienced.

0:23:47 > 0:23:50ALARM BEEPS

0:23:53 > 0:23:56'Jacqueline is a new lady that was just brought down to us yesterday.

0:23:56 > 0:23:59'She's a young lady with breast cancer

0:23:59 > 0:24:03'and she's had chemo, she's had the surgery, she's had everything,

0:24:03 > 0:24:06'but unfortunately the disease has come back.

0:24:06 > 0:24:08'So now it is all about supportive measures,

0:24:08 > 0:24:10'but she has a really good family support,

0:24:10 > 0:24:12'which is so lovely to see and it's...

0:24:12 > 0:24:14'It makes our job a lot easier when the family are there,

0:24:14 > 0:24:16'helping them through.' Hello, Jacqueline.

0:24:16 > 0:24:19- Hiya.- Morning.- We're in to do the bloods, is that OK?

0:24:21 > 0:24:24Sometimes you find yourself getting too close to patients.

0:24:24 > 0:24:26You know, you get trained on how to break bad news

0:24:26 > 0:24:29and how to tell somebody that somebody's died.

0:24:29 > 0:24:30But I was on a night shift,

0:24:30 > 0:24:33'and there was a patient of ours recently

0:24:33 > 0:24:35'who I was a very close with, and I thought I'd pop down...'

0:24:35 > 0:24:37That's going to be really tight, OK?

0:24:37 > 0:24:39But it'll help. The tighter, the better.

0:24:39 > 0:24:44I went into the main office and her name wasn't on the board any more,

0:24:44 > 0:24:45and that was how I found out.

0:24:45 > 0:24:47And that...

0:24:47 > 0:24:48You know, that was no-one's fault,

0:24:48 > 0:24:51but that wasn't a nice way to find out.

0:24:51 > 0:24:53And, in that way, it is difficult,

0:24:53 > 0:24:55so it's about finding that balance.

0:24:55 > 0:24:56Stop.

0:24:56 > 0:24:58Sometimes it does that.

0:24:58 > 0:24:59That's what Gordon said.

0:25:03 > 0:25:06Every person that's passed away in this unit

0:25:06 > 0:25:08has done so comfortably,

0:25:08 > 0:25:11peacefully and surrounded by their families, every time.

0:25:13 > 0:25:15That, for me, has been...

0:25:15 > 0:25:17It's really helped me deal with it in my own head and say,

0:25:17 > 0:25:19"Yes, these patients are dying,

0:25:19 > 0:25:21"but it's a successful death."

0:25:21 > 0:25:23We're all going to die someday and I think, if I did,

0:25:23 > 0:25:24that's how I'd want it.

0:25:24 > 0:25:26I'd want to be peaceful and comfortable

0:25:26 > 0:25:28and surrounded by my family, so, you know,

0:25:28 > 0:25:30you can't really ask any more than that.

0:25:39 > 0:25:41At the Royal Victoria Hospital,

0:25:41 > 0:25:4467-year-old James McCabe has responded well

0:25:44 > 0:25:46to his clot-busting medication.

0:25:47 > 0:25:49Mr McCabe has had a fantastic outcome

0:25:49 > 0:25:50after getting the clot-buster drug,

0:25:50 > 0:25:53which was given to him really very quickly

0:25:53 > 0:25:55after onset of the stroke.

0:25:55 > 0:25:57And I suppose that's the thing about stroke,

0:25:57 > 0:25:59it can be really devastating

0:25:59 > 0:26:01and, hopefully, you can see

0:26:01 > 0:26:04that the systems we have set up in our hospitals

0:26:04 > 0:26:08allow us to try to respond to people having a stroke urgently.

0:26:08 > 0:26:11We get there as quickly as we can.

0:26:11 > 0:26:15I can't thank Doctor Kerr and the medical team enough.

0:26:15 > 0:26:19They explained everything, bit by bit,

0:26:19 > 0:26:22because, at the time, it was frightening.

0:26:22 > 0:26:24You couldn't get the words out.

0:26:24 > 0:26:28You had them in your brain, but they wouldn't come out.

0:26:28 > 0:26:31With the care of Doctor Kerr and his team,

0:26:31 > 0:26:33it was bloody marvellous.

0:26:33 > 0:26:37You couldn't be in a better place than it actually happened.

0:26:45 > 0:26:48It's now been seven weeks since Grace's surgery.

0:26:49 > 0:26:52And it's improving the shape of my face,

0:26:52 > 0:26:55and it's giving me the symmetry with the other side

0:26:55 > 0:26:58and I feel that that in itself

0:26:58 > 0:27:01is helping me feel a lot more confident going out and about

0:27:01 > 0:27:02when people aren't just staring at me

0:27:02 > 0:27:04the same as they were in the past.

0:27:06 > 0:27:07Each surgery that has taken place

0:27:07 > 0:27:11has really improved my inner feeling about myself

0:27:11 > 0:27:14and I definitely feel a lot more confident.

0:27:14 > 0:27:17And with her oral surgery now complete...

0:27:17 > 0:27:20We've got your bridge back from the laboratory.

0:27:20 > 0:27:23..Grace is finally able to be fitted with a permanent bridge.

0:27:23 > 0:27:26So, what do you think, Grace? What you think of them?

0:27:26 > 0:27:28I think they're wonderful. Thank you. Yeah.

0:27:28 > 0:27:30- Really pleased with them. - It's looks lovely.

0:27:30 > 0:27:32- I love them.- Yeah?

0:27:32 > 0:27:36It's lovely just to think now that I have permanent teeth.

0:27:36 > 0:27:38They're absolutely wonderful and I'm delighted with them.

0:27:38 > 0:27:40And it's a new smile,

0:27:40 > 0:27:42a new chewing technique

0:27:42 > 0:27:44and everything's great.

0:27:45 > 0:27:49She really thinks it looks really good and I'm really pleased.

0:27:49 > 0:27:52It's very rewarding sort of work, this, and such a good result.

0:27:53 > 0:27:55Everything is moving forward,

0:27:55 > 0:27:59and I'm delighted with it and I feel that I'm really getting there now.

0:27:59 > 0:28:02One thing it's given to me, as I've said before

0:28:02 > 0:28:05and will continue to say for the rest of my days,

0:28:05 > 0:28:08is that they've given me quality of life

0:28:08 > 0:28:10and they've given me my life back

0:28:10 > 0:28:13and I never will be able to thank them enough for that.