0:00:26 > 0:00:28- Hannah, have you got your shoes on? - Yes.- Yeah?
0:00:28 > 0:00:31- What about your coat?- Yes. - Have you got your homework?
0:00:31 > 0:00:34- Yes.- Stop playing with the rabbit!
0:00:34 > 0:00:39- Have you got your lunchbox?- Yes. - Come on, then. Hurry up, Hannah!
0:00:39 > 0:00:41- Have you rung the garage yet? - Not yet.
0:00:42 > 0:00:44Oh, love, it's on its last legs!
0:00:44 > 0:00:45I'll do it today.
0:00:47 > 0:00:48Oh, gosh!
0:00:50 > 0:00:52Sorry, did we wake you up?
0:00:56 > 0:00:58Bad night?
0:00:59 > 0:01:01Have a lie-in.
0:01:01 > 0:01:03I'll come and help once I've dropped madam off.
0:01:05 > 0:01:06I'll manage.
0:01:08 > 0:01:11Mum, I don't mind helping.
0:01:11 > 0:01:12Hi, Grandma.
0:01:12 > 0:01:15Morning, love.
0:01:15 > 0:01:16Come on, you. School!
0:01:18 > 0:01:23SHE WHEEZES
0:01:29 > 0:01:31THEY MOAN
0:01:31 > 0:01:32- Stay.- No.
0:01:33 > 0:01:35No, I have to get to work.
0:01:37 > 0:01:38I could lie here all day,
0:01:38 > 0:01:43having no meaningful employment to prise me from my bed.
0:01:43 > 0:01:44Or should I say YOUR bed?
0:01:47 > 0:01:52You have only been looking for a few days, and trying to find work
0:01:52 > 0:01:55at the weekend is never a good idea.
0:01:55 > 0:01:58Thank you. For not saying "I told you so2.
0:02:02 > 0:02:05I'm sure you will find something soon.
0:02:05 > 0:02:09Ah! The lawn needs cutting.
0:02:09 > 0:02:13Why do these weeds grow so much quicker than my bedding plants?
0:02:13 > 0:02:16- One of life's little mysteries.- Hm.
0:02:16 > 0:02:19Right. Might as well make a start.
0:02:19 > 0:02:21I think it is going to be a fine day.
0:02:21 > 0:02:24Make sure you find the time to enjoy it.
0:02:24 > 0:02:26I can relax when I've found a job.
0:02:26 > 0:02:29If I lose one, I get another. That's how it's been all my life.
0:02:30 > 0:02:32Until now.
0:02:33 > 0:02:39You will be fine and, if you need some help to tide you over, I will help.
0:02:45 > 0:02:50Here you go. Welcome to the VPAS team.
0:02:50 > 0:02:53So, how was the course?
0:02:53 > 0:02:54It was brilliant. We learned loads.
0:02:54 > 0:02:58I loved it, especially the role play. It was very insightful.
0:02:58 > 0:03:02I actually got quite tearful when I was a housebound widow with angina.
0:03:02 > 0:03:03She did actually cry.
0:03:03 > 0:03:08I did. That's empathy. I'm quite an empathetic person.
0:03:08 > 0:03:09What are you talking about?
0:03:11 > 0:03:13Ha!
0:03:13 > 0:03:14"Vuh-Paz"?
0:03:14 > 0:03:16It's pronounced "Vee Pass".
0:03:16 > 0:03:18- Is it now?- Oh, here we go!
0:03:18 > 0:03:21So, this is this year's sticking plaster for that
0:03:21 > 0:03:23ever-increasing wound in the NHS budget.
0:03:23 > 0:03:24At least we're doing something.
0:03:24 > 0:03:29Amateurs shouldn't meddle. This will end in tears, Hollins. Always does.
0:03:32 > 0:03:38SHE WHEEZES
0:03:44 > 0:03:47You should have waited. There's plenty of time.
0:03:56 > 0:03:59Hannah's supposed to take that to school.
0:04:00 > 0:04:02I'll drop it off later.
0:04:02 > 0:04:04She doesn't need it till this afternoon.
0:04:07 > 0:04:08Dodgy knees.
0:04:08 > 0:04:11Maybe I can get Dr Reid to take a look after she's sorted you out.
0:04:12 > 0:04:14Shall we take the wheelchair?
0:04:16 > 0:04:18What are you up to?
0:04:18 > 0:04:20I'm choosing a father for my baby.
0:04:22 > 0:04:24So, what do you think?
0:04:25 > 0:04:28Software engineer or tennis coach?
0:04:28 > 0:04:31The one in the shorts. Bit out of your league, though.
0:04:31 > 0:04:33I'm not looking for a relationship.
0:04:33 > 0:04:35It's purely a financial arrangement.
0:04:35 > 0:04:37I send money, they send sperm.
0:04:37 > 0:04:39You can't do that. It's unethical.
0:04:40 > 0:04:42It's against the law to sell sperm.
0:04:42 > 0:04:43In this country.
0:04:45 > 0:04:48Ohio? You're buying it from the US?
0:04:48 > 0:04:52Yeah, Americans are so much more relaxed about this sort of thing.
0:04:52 > 0:04:55They ship worldwide in tanks of liquid nitrogen.
0:04:55 > 0:04:57I suppose that's why it's so expensive.
0:04:57 > 0:04:59- That and the vetting.- Vetting?
0:04:59 > 0:05:02Yeah, background checks, references.
0:05:02 > 0:05:05Gold Star Donor Dads weed out the fakers and the slackers,
0:05:05 > 0:05:08- leaving you to focus on the important things.- Valerie...
0:05:08 > 0:05:11So what do you think? Blond or brunette?
0:05:11 > 0:05:14I think it's really great that you're putting so much thought into this.
0:05:14 > 0:05:18I mean, my mum got wasted and met some bloke down the pub.
0:05:18 > 0:05:19There's a "but" here, isn't there?
0:05:19 > 0:05:23In a few years, you could have a four-year-old asking about their daddy.
0:05:23 > 0:05:25You might want to have a think about that.
0:05:25 > 0:05:27I would have loved to have known my dad.
0:05:27 > 0:05:31I don't know, it's like... It's like I'm missing half the story.
0:05:39 > 0:05:40Oh, goodness!
0:05:42 > 0:05:44- There you go.- Thank you.
0:05:44 > 0:05:46You're welcome.
0:05:46 > 0:05:48Elizabeth Hopkin for Dr Reid.
0:05:48 > 0:05:49Oh, look, perfect timing.
0:05:49 > 0:05:52Mrs Hopkin, hello. Would you like to come through this way?
0:05:54 > 0:05:56I want to do this on my own.
0:05:56 > 0:05:57Don't be silly.
0:05:58 > 0:05:59Please, love.
0:05:59 > 0:06:00Mum...
0:06:02 > 0:06:05- You ready?- Mm.- OK, just take it slowly.
0:06:12 > 0:06:13She'll be fine.
0:06:18 > 0:06:19Oh, dear!
0:06:23 > 0:06:25- Oh, are you OK?- Sorry.
0:06:25 > 0:06:29No, no, you don't have to apologise. Are you worried about your mum?
0:06:29 > 0:06:35She's been through so much. She's got emphysema. It's getting worse.
0:06:35 > 0:06:37I can't bear the thought of losing her.
0:06:37 > 0:06:43Oh, hey. We see a lot of patients with lung problems and, honestly, you know,
0:06:43 > 0:06:48loads of them manage just fine once they stop the smoking, they get on the right meds.
0:06:48 > 0:06:50Mum's never smoked.
0:06:50 > 0:06:54She's not dragging about a bottle of oxygen because of a bad lifestyle choice.
0:06:55 > 0:06:58Makes it even harder for her, being judged.
0:06:58 > 0:06:59I didn't mean to.
0:07:01 > 0:07:04Non-smokers don't get emphysema, right? Well, they do.
0:07:05 > 0:07:07I'm sorry. I didn't mean to jump to...
0:07:07 > 0:07:09Everyone assumes she's been puffing away for years.
0:07:09 > 0:07:15Mum's sick cos she hasn't got enough Alpha 1 in her body to protect her lungs.
0:07:15 > 0:07:16Alpha 1?
0:07:16 > 0:07:17It's a protein.
0:07:19 > 0:07:22Most people produce enough to keep their lungs safe.
0:07:22 > 0:07:23Safe from what?
0:07:23 > 0:07:29Pollution, dust, bacteria, viruses.
0:07:31 > 0:07:35So her lungs get damaged just from breathing?
0:07:35 > 0:07:38If you're an Alpha, you've got to be really careful.
0:07:38 > 0:07:43No aerosols, no bonfires, people with colds, and definitely no smoking.
0:07:43 > 0:07:47Do you know? We had another patient, couple of years back,
0:07:47 > 0:07:52and she moved abroad.
0:07:52 > 0:07:54For the treatment?
0:07:54 > 0:07:56Um... There's a treatment?
0:07:56 > 0:08:00Alpha 1 augmentation therapy - that's why we're here.
0:08:00 > 0:08:02Mum's volunteered for a drugs trial.
0:08:06 > 0:08:09So, how are you?
0:08:10 > 0:08:14Bit better since the infection cleared up.
0:08:14 > 0:08:15Good.
0:08:17 > 0:08:19Lizzie, I'm going to get straight to the point.
0:08:21 > 0:08:24It's bad news about the trial, I'm afraid.
0:08:24 > 0:08:28The research team think that your condition is too far advanced.
0:08:30 > 0:08:32So the treatment won't work on me?
0:08:34 > 0:08:38It's not that it wouldn't work. It could very well slow the progression
0:08:38 > 0:08:44of your emphysema. The problem is that you don't meet the criteria.
0:08:46 > 0:08:49You've lost too much lung function already,
0:08:49 > 0:08:54and it's a lengthy trial. They want to focus on patients
0:08:54 > 0:08:56who are going to benefit the most.
0:09:00 > 0:09:01I'm sorry.
0:09:01 > 0:09:03I know it's disappointing.
0:09:08 > 0:09:11- They said no?- It's all right.
0:09:11 > 0:09:14No, it's not all right. Can't you do something?
0:09:14 > 0:09:15Make them change their minds?
0:09:15 > 0:09:17Mel, let's go.
0:09:17 > 0:09:18This was her last chance!
0:09:18 > 0:09:20Look, I appreciate you're upset.
0:09:20 > 0:09:23"Upset" doesn't even begin to describe it!
0:09:23 > 0:09:25Shouting at Dr Reid isn't going to help.
0:09:25 > 0:09:26Well, it helps me!
0:09:26 > 0:09:30I am sick and tired of watching you get worse and worse.
0:09:30 > 0:09:32I'm sorry. Is there a problem?
0:09:32 > 0:09:35Oh, can you prescribe Alpha 1 antitrypsin therapy?
0:09:35 > 0:09:36Please, love.
0:09:36 > 0:09:39I am not a clinician. I am the practice manager.
0:09:39 > 0:09:42Oh, well, perhaps you'd like to explain to my mother why the NHS
0:09:42 > 0:09:46doesn't provide the only treatment that can stop her lungs from disintegrating?
0:09:46 > 0:09:50Melissa! Please don't.
0:09:55 > 0:09:56Take care.
0:10:06 > 0:10:08What is Alpha 1?
0:10:08 > 0:10:11It's an inherited genetic condition.
0:10:11 > 0:10:12Genetic?
0:10:12 > 0:10:13Yes, Valerie. Genetic.
0:10:14 > 0:10:15I need caffeine.
0:10:25 > 0:10:30CAR ENGINE SPLUTTERS
0:10:32 > 0:10:34I warned Tom to sort it.
0:10:38 > 0:10:41Breakdown service. Come on!
0:10:44 > 0:10:45Have you got it?
0:10:48 > 0:10:51Here we go. Auto Rescue.
0:10:55 > 0:10:57Have you got Alpha 1?
0:11:05 > 0:11:07I reckon Mr Keats should go on the VPAS list.
0:11:07 > 0:11:09Heavy smoker, misses half his appointments.
0:11:09 > 0:11:11- At least he took the leaflet. - That's good.
0:11:11 > 0:11:14- The giving up smoking one?- Yeah.
0:11:14 > 0:11:17Dumped that in reception on his way out.
0:11:17 > 0:11:19Right, well, I'll schedule a visit.
0:11:19 > 0:11:22Why can't we just concentrate on the people who would actually like our help?
0:11:22 > 0:11:23What's up?
0:11:23 > 0:11:27Mrs Hopkin. Why can't she get the treatment that she needs?
0:11:27 > 0:11:28It's complicated.
0:11:29 > 0:11:32She hasn't got enough of this Alpha 1 in her system,
0:11:32 > 0:11:33so her lungs get damaged.
0:11:33 > 0:11:35Top up the Alpha 1 - lungs protected.
0:11:35 > 0:11:37Bingo, everybody's happy.
0:11:37 > 0:11:41Alpha 1 therapy is very expensive.
0:11:41 > 0:11:44A patient has to have it at least every week for the rest of their life.
0:11:44 > 0:11:47- It's all about the money. - No, it's about value for money.
0:11:48 > 0:11:50A lifetime's treatment can cost up to
0:11:50 > 0:11:52a million or more - that's just for one person.
0:11:52 > 0:11:54A million pounds?!
0:11:54 > 0:11:58Yes, and there's still a question mark over how effective it is.
0:11:58 > 0:11:59And you're saying it doesn't work?
0:11:59 > 0:12:03No, I'm saying that it's difficult to prove how much difference it makes.
0:12:15 > 0:12:16PHONE RINGS
0:12:19 > 0:12:25Hello? Yeah. Thanks for getting back.
0:12:25 > 0:12:28Andy Coleman mentioned you were looking for casual staff?
0:12:32 > 0:12:38Oh, no. OK. No problem. Thanks anyway. Yeah, bye.
0:12:43 > 0:12:45All right. Thanks, Carol.
0:12:46 > 0:12:48You have to get Melissa on the trial!
0:12:48 > 0:12:50It's just not possible.
0:12:50 > 0:12:55Her lung function's not too bad. If she starts the treatment now,
0:12:55 > 0:12:57- she doesn't need to get like this. - Mum!
0:12:57 > 0:13:00Lizzie, the trial is full.
0:13:00 > 0:13:02They have all the patients they need.
0:13:04 > 0:13:05Come and sit down.
0:13:05 > 0:13:07SHE WHEEZES
0:13:11 > 0:13:14I tried. After your appointment,
0:13:14 > 0:13:17I called Professor Caine and I asked him to reconsider.
0:13:19 > 0:13:20But...
0:13:22 > 0:13:23I'm sorry.
0:13:27 > 0:13:29I have decided that you are my best option.
0:13:31 > 0:13:32What?
0:13:32 > 0:13:35I need some information on genetics, and you're my go-to person when
0:13:35 > 0:13:38it comes to anything scientific or technical.
0:13:38 > 0:13:40What's your interest in genetics?
0:13:40 > 0:13:42I would rather not say at this stage.
0:13:42 > 0:13:46Are we talking Mendelian inheritance, mitochondrial DNA, gene expression? Take your pick.
0:13:46 > 0:13:47Never mind.
0:13:50 > 0:13:52- Good weekend?- Ha.
0:13:56 > 0:13:58Do you want to sit here? I'll get your wheelchair.
0:14:07 > 0:14:08SHE COUGHS
0:14:10 > 0:14:13She's an Alpha 1. Same as me.
0:14:15 > 0:14:16Cab for Mrs Hopkin?
0:14:17 > 0:14:19Oh, um... Well, I'll...
0:14:22 > 0:14:26That's why I insisted on going back in to see the doctor.
0:14:26 > 0:14:27Any joy from Dr Reid?
0:14:29 > 0:14:32Do you think I'm silly to make a fuss?
0:14:33 > 0:14:37No, of course not. I would break doors down for my kids.
0:14:45 > 0:14:46Ta.
0:14:48 > 0:14:49St Phil's, please.
0:14:52 > 0:14:56Poor lady! You take it for granted, don't you - breathing?
0:15:02 > 0:15:05- Well, I hope you're pleased with yourself!- Sorry?
0:15:05 > 0:15:07Putting ideas into Mum's head.
0:15:07 > 0:15:09All she needs is a wild goose chase to St Phil's.
0:15:09 > 0:15:11I didn't tell her to go to St Phil's.
0:15:11 > 0:15:15She's planning on kicking Professor Caine's door down.
0:15:15 > 0:15:16He's running the clinical trial.
0:15:16 > 0:15:19Now, I need to be here for the breakdown service, and I can't trust
0:15:19 > 0:15:21her in a cab, and now I'll have to drag my husband out of work,
0:15:21 > 0:15:24so if you'll just mind your own business!
0:15:26 > 0:15:27Mum?
0:15:41 > 0:15:42Mum!
0:15:42 > 0:15:43I'm all right.
0:15:43 > 0:15:45You have to stop this now!
0:15:45 > 0:15:46I'm not going home.
0:15:46 > 0:15:48You're not going to St Phil's!
0:15:48 > 0:15:50I can protest here.
0:15:50 > 0:15:54Hardly anyone knows about Alpha 1, and it's time they did.
0:15:54 > 0:15:57Karen, can you help me with the cardboard, please?
0:15:57 > 0:16:00What makes you think this protest's going to make any difference?
0:16:00 > 0:16:05Love, if you want to make things happen, you've got to cause a stir.
0:16:05 > 0:16:08Now, you can help me or you can walk away.
0:16:15 > 0:16:17Oh, what a surprise!
0:16:17 > 0:16:19It's not a good time?
0:16:19 > 0:16:22It's just that I have a meeting.
0:16:22 > 0:16:25- I shouldn't have come.- No, no, of course I am glad to see you.
0:16:25 > 0:16:27It's just that this is a...
0:16:27 > 0:16:28Well, it is a busy week.
0:16:28 > 0:16:30Are you trying to get shot of me already?
0:16:30 > 0:16:33No, no! No, I am glad to see you.
0:16:35 > 0:16:38One moment, please.
0:16:39 > 0:16:41How long has this been going on?
0:16:41 > 0:16:44Mrs Hopkin? Not long. I was just about to give you a call.
0:16:44 > 0:16:47Well, I am very sorry for her predicament, but if they want to protest,
0:16:47 > 0:16:49they should do it outside Parliament!
0:16:49 > 0:16:50But their car's broken down.
0:16:50 > 0:16:55And public transport's not very good when you're dragging an oxygen tank.
0:16:56 > 0:16:57I'd better get on.
0:16:57 > 0:16:59Right. Well, I will see you later.
0:17:02 > 0:17:03Day off?
0:17:04 > 0:17:07No, he's just between jobs.
0:17:07 > 0:17:12Right. Well, I had better go. Please tell Dr Clay what is happening.
0:17:14 > 0:17:18Mrs Hollins, I do not expect to see her there when I return.
0:17:25 > 0:17:31Thank you. They said they may send someone over later.
0:17:31 > 0:17:33And maybe they won't.
0:17:33 > 0:17:35How long do you plan to keep this up?
0:17:35 > 0:17:37As long as it takes.
0:17:37 > 0:17:39It's not as if I've got to be somewhere else, is it?
0:17:39 > 0:17:42And what happens when your oxygen runs out?
0:17:42 > 0:17:44Then you can bring me some more.
0:17:44 > 0:17:45Haven't I got enough on my plate?
0:17:50 > 0:17:53- I don't need it so much if I sit still.- Mum...
0:17:54 > 0:17:57..don't do this to yourself.
0:17:57 > 0:17:58You could catch cold.
0:17:58 > 0:18:01You could end up with pneumonia again.
0:18:01 > 0:18:04Hannah was terrified you were going to die the last time.
0:18:04 > 0:18:06I'm doing this for Hannah.
0:18:07 > 0:18:12No child should grow up watching their parent turn into an invalid.
0:18:12 > 0:18:14No. No, they shouldn't. But this isn't the way.
0:18:16 > 0:18:20We could look into leaving England, moving abroad.
0:18:20 > 0:18:22Clutching at straws!
0:18:22 > 0:18:25This is all my fault.
0:18:25 > 0:18:26No.
0:18:27 > 0:18:34I gave you this. I gave you Alpha 1.
0:18:34 > 0:18:36Mum, it's not your fault.
0:18:36 > 0:18:38SHE COUGHS
0:18:40 > 0:18:44Did you know that almost all diseases have a genetic component?
0:18:44 > 0:18:46Can't say I've given it much thought.
0:18:46 > 0:18:49Well, you should, especially if you're thinking of bringing
0:18:49 > 0:18:50a child into the world.
0:18:51 > 0:18:54There's more than blonde hair and a good backhand at stake.
0:18:54 > 0:18:56Finally, you've seen sense.
0:18:56 > 0:18:58It's a reproductive nightmare out there.
0:18:58 > 0:19:00Does this mean it's off?
0:19:00 > 0:19:04No, it just means I'm going to look closer to home.
0:19:04 > 0:19:06Not here?
0:19:06 > 0:19:11Well, I wouldn't see that there should be an issue. It's a male imperative to spread their seed.
0:19:11 > 0:19:13So who? Sid?
0:19:13 > 0:19:16No, he's a bit nervy. I bet he cried a lot as a baby.
0:19:16 > 0:19:18Mm. Jimmi?
0:19:19 > 0:19:21There's quite a lot of baggage there.
0:19:23 > 0:19:24Rob?
0:19:24 > 0:19:27Plodding. No, actually, I'd prefer a doctor.
0:19:27 > 0:19:28Al!
0:19:28 > 0:19:32What, and lumber my baby with the stroppy know-it-all gene? No.
0:19:32 > 0:19:35That leaves Heston or Daniel.
0:19:35 > 0:19:36Heston!
0:19:37 > 0:19:40Can you really imagine loving a little baby with Heston's face?
0:19:42 > 0:19:43Yes.
0:19:49 > 0:19:52I need to drop something at my daughter's school.
0:19:52 > 0:19:53Can you keep an eye on Mum?
0:19:53 > 0:19:57Of course, yes. Sorry... How did she get on with the Gazette?
0:19:59 > 0:20:03They're not interested. Two women sitting in a car park?
0:20:03 > 0:20:06It's not much of a story, is it? She already feels invisible.
0:20:06 > 0:20:08And about social media?
0:20:09 > 0:20:10Have a go at that, did she?
0:20:10 > 0:20:14Mm. Well, her 25 online buddies are very sympathetic but,
0:20:14 > 0:20:16apart from that, nobody cares.
0:20:25 > 0:20:29Hi. Could I speak to Lisa Watson, please, of the editorial department?
0:20:34 > 0:20:38Hi, I'm calling from the Mill Health Centre. I understand you're sending
0:20:38 > 0:20:43a TV crew to cover the protest here? Oh!
0:20:43 > 0:20:50Oh, that's a relief. Oh, yeah, we really don't want any publicity to escalate the situation.
0:20:51 > 0:20:57Oi! Put that chair down! ..I'm so sorry. We're hoping that the police
0:20:57 > 0:20:59are going to come over shortly and sort it all out.
0:20:59 > 0:21:00I've got to go.
0:21:11 > 0:21:12Do you fancy coming in for a cuppa?
0:21:14 > 0:21:17I should be here, in case a journalist comes.
0:21:17 > 0:21:20Well, we can keep an eye out from reception.
0:21:21 > 0:21:23Yay!
0:21:23 > 0:21:27What you need is some supporters to help you man the barricades.
0:21:27 > 0:21:29Can you hold that for me?
0:21:29 > 0:21:32See, it's amazing what you can organise with
0:21:32 > 0:21:35a smartphone and the right contacts.
0:21:38 > 0:21:39There we go.
0:21:42 > 0:21:43Sperm donor?
0:21:44 > 0:21:48What would I have to take into consideration, medically speaking?
0:21:48 > 0:21:53Um, well...the fertility clinic will take care of all of that side of things.
0:21:53 > 0:21:56Oh, I don't think I want to go through a clinic.
0:21:56 > 0:21:58I don't much fancy being impregnated by a stranger.
0:22:00 > 0:22:02Yeah, I'd rather use somebody I know.
0:22:03 > 0:22:09OK. Well, Valerie, I would strongly advise against DIY sperm donation.
0:22:09 > 0:22:10It can get very complicated.
0:22:10 > 0:22:11Humour me.
0:22:13 > 0:22:17OK. Well, the donor has to be in good health, free from any STIs, there have to be no
0:22:17 > 0:22:21underlying conditions, you have to be aware of any genetic issues.
0:22:21 > 0:22:27Oh, I'm very mindful of rogue genes. So, would you be willing to
0:22:27 > 0:22:29donate your sperm, hypothetically?
0:22:33 > 0:22:34Probably not.
0:22:34 > 0:22:36May I ask why?
0:22:36 > 0:22:38I'm just trying to get a male perspective.
0:22:38 > 0:22:43I... If I'm going to father a child, I think I'd probably want to be involved.
0:22:45 > 0:22:49So if I was going to create a life, I'd want to be there to be part of it.
0:22:49 > 0:22:56And then, of course, there's the woman. She would be important as well.
0:22:59 > 0:23:00Is that all?
0:23:01 > 0:23:02Thanks.
0:23:11 > 0:23:18- PROTESTORS:- Save our NHS! Help the Alphas! Save our NHS! Help the Alphas!
0:23:18 > 0:23:21I want to help the Alphas as well, but if you block the entrance,
0:23:21 > 0:23:23I'm going to have to call the police.
0:23:23 > 0:23:25What is going on here?
0:23:25 > 0:23:26Help the Alphas!
0:23:27 > 0:23:30Mrs Hollins, I asked you to deal with this!
0:23:30 > 0:23:33They're community activists. I think Mrs Hopkin must have called them.
0:23:33 > 0:23:37I am sorry, you are trespassing on private property.
0:23:37 > 0:23:39I will have to ask you to leave.
0:23:39 > 0:23:42- Do you want me to call Rob? - No. No, I will deal with this myself, thank you.
0:23:42 > 0:23:44Where did all these people come from? Where's Mum?
0:23:44 > 0:23:46Your mum's been very busy.
0:23:49 > 0:23:51- Lizzie?- Mum?
0:23:51 > 0:23:52- Lizzie!- Mum!
0:23:52 > 0:23:54Karen, call an ambulance.
0:23:54 > 0:23:56LIZZIE GROANS
0:23:56 > 0:24:02All right, Lizzie. Don't panic. All right. Slow breaths, remember? Purse your lips.
0:24:02 > 0:24:04That's it. Through your nose. That's it.
0:24:04 > 0:24:06- Ambulance, please.- Well done.
0:24:06 > 0:24:08- All right. Don't panic. Purse your lips.- Mill Health Centre.
0:24:08 > 0:24:11LIZZIE GROANS
0:24:11 > 0:24:13- KNOCK ON DOOR - Come in.
0:24:16 > 0:24:18What?
0:24:18 > 0:24:20I've decided who my sperm donor is going to be.
0:24:23 > 0:24:24Daniel.
0:24:24 > 0:24:29He's the obvious choice, really. I mean, he's intelligent, tall, good-looking.
0:24:29 > 0:24:31He's already sired two healthy offspring.
0:24:31 > 0:24:34Valerie, I'm not sure you've thought this through.
0:24:34 > 0:24:38Don't you think Daniel might want a say in it?
0:24:38 > 0:24:40I'll tell him when he gets back from holiday.
0:24:46 > 0:24:49Karen, do me a favour. Get rid of that lot, will you?
0:24:49 > 0:24:52No, no! I want them to see.
0:24:53 > 0:24:59- You... You've got to talk to them. - Mum...- Tell them about Alpha.
0:25:09 > 0:25:10Could you tell us what's going on?
0:25:10 > 0:25:13My mum, Lizzie Hopkin, is the bravest person I know.
0:25:14 > 0:25:16She has a rare genetic disorder called
0:25:16 > 0:25:19Alpha 1 antitrypsin deficiency.
0:25:20 > 0:25:22She's lost her home, her job...
0:25:22 > 0:25:26- This is my fault. I encouraged her. - ..her independence because of it...
0:25:26 > 0:25:28I'm not cut out to work with vulnerable patients.
0:25:28 > 0:25:32- Karen, don't be silly.- Every day gets harder for her to breathe... - Some of our patients have no-one.
0:25:32 > 0:25:34..harder to do the most basic of things for herself.
0:25:34 > 0:25:36You can make a difference. You already have.
0:25:36 > 0:25:38All of this because her body doesn't produce enough of
0:25:38 > 0:25:41a protein that should protect her lungs.
0:25:49 > 0:25:51You bunking off early?
0:25:51 > 0:25:53No, I'm just trying to be spontaneous.
0:25:53 > 0:25:54I'm leading you astray.
0:25:54 > 0:25:57Well, there is a little time before my next meeting.
0:25:57 > 0:26:00So, what have you been up to?
0:26:00 > 0:26:01Cleaning out your pots.
0:26:03 > 0:26:05Did I do something wrong? They were full of dead stuff.
0:26:07 > 0:26:13Well, no, not dead. Dormant. Late-flowering perennials.
0:26:13 > 0:26:15I'm so sorry. I'll replant them.
0:26:15 > 0:26:16JJ...
0:26:16 > 0:26:20- it is all right. - I've trashed your plants!
0:26:20 > 0:26:22You were trying to help. It is a lovely thought.
0:26:22 > 0:26:25I really do appreciate you trying to contribute,
0:26:25 > 0:26:26but I do not expect it.
0:26:26 > 0:26:30I expect it. Unfortunately, I'm knocking on and unemployed.
0:26:30 > 0:26:31So my options are limited.
0:26:33 > 0:26:34Why don't you move in?
0:26:34 > 0:26:36Until you are back on your feet?
0:26:36 > 0:26:37Well, that's a big step.
0:26:39 > 0:26:42Is this a ruse to try to get me into bed permanently?
0:26:42 > 0:26:48What...no! Practical measures, that is all.
0:26:48 > 0:26:50So you're offering me the spare room?
0:26:51 > 0:26:54We do not need to change the sleeping arrangements.
0:26:56 > 0:27:00I just want to help you financially, that is all.
0:27:02 > 0:27:05You know, there's a word for a man who gets paid for his...services.
0:27:07 > 0:27:09I am being serious.
0:27:10 > 0:27:12Do you want to move in or not?
0:27:22 > 0:27:26Ooh! Assignation with the head-shrinker.
0:27:26 > 0:27:29- What did you eat for lunch? Razor blades?- What?
0:27:29 > 0:27:32No one person is a superhero.
0:27:32 > 0:27:33Except you. Die-hard Hollins!
0:27:33 > 0:27:36One more stunt like that and you're out of here.
0:27:36 > 0:27:38- Look, she rang me. - If she rings, don't answer!
0:27:38 > 0:27:42You used to be there on my friendship scale.
0:27:42 > 0:27:44Right now, you're there.