0:00:02 > 0:00:04Holby Trust remains. St Francis will merge with us.
0:00:05 > 0:00:08Don't forget - the new Neuro consultant starts today.
0:00:08 > 0:00:10They like to mark their territory.
0:00:10 > 0:00:12If you're willing, I'd like us to start again.
0:00:12 > 0:00:13Let me be your case study.
0:00:13 > 0:00:16But isn't it designed for people with dementia?
0:00:18 > 0:00:19I'm sorry, I had no idea.
0:00:19 > 0:00:21Roxanna's dementia project - choose hers.
0:00:26 > 0:00:27Why are you hiding in here?
0:00:27 > 0:00:29I don't know.
0:00:29 > 0:00:32You and me - we've got to stick together more than ever.
0:01:16 > 0:01:18What would you say if I told you I was leaving?
0:01:18 > 0:01:21Leaving this place for good, leaving Holby.
0:01:21 > 0:01:24I'd say I didn't know what you're talking about.
0:01:24 > 0:01:26Exactly what I just said.
0:01:26 > 0:01:28That I don't believe you?
0:01:28 > 0:01:30And then?
0:01:30 > 0:01:32You mean it?
0:01:32 > 0:01:35Never been more uncertain about anything.
0:02:14 > 0:02:15I'm close.
0:02:22 > 0:02:24O aviao esta pronto para partir.
0:02:25 > 0:02:26And those papers?
0:02:29 > 0:02:30Thank you.
0:02:31 > 0:02:34- Could you please let the others know?- OK.
0:02:39 > 0:02:42- Any updates, you know where to find me.- OK.
0:03:00 > 0:03:01The miracle man.
0:03:02 > 0:03:07Because, for some reason, he found me to be his vessel.
0:03:09 > 0:03:10I have nothing.
0:03:12 > 0:03:14I'm nobody.
0:03:14 > 0:03:15Just Laszlo.
0:03:15 > 0:03:16I'm alone and...
0:03:16 > 0:03:18DOG BARKS
0:03:21 > 0:03:23OK, not alone - I had Rolo.
0:03:26 > 0:03:29But motor neuron disease.
0:03:29 > 0:03:32I was running out of days.
0:03:32 > 0:03:33Breathing, swallowing...
0:03:33 > 0:03:35always weaker, every day.
0:03:39 > 0:03:41Then this man finds me
0:03:41 > 0:03:43and he tells me that he can make me feel better.
0:03:43 > 0:03:45That I will walk again.
0:03:48 > 0:03:49I'm a religious man.
0:03:50 > 0:03:52Can you imagine meeting someone
0:03:52 > 0:03:54who tells you that he can make you walk again?
0:03:56 > 0:03:57Now look at me.
0:04:00 > 0:04:03INDISTINCT
0:04:06 > 0:04:08The professor did this.
0:04:13 > 0:04:17Mr Gaskell gave me a second life.
0:04:19 > 0:04:22Is it just me or did Rolo seem a little staged?
0:04:22 > 0:04:26Olly! He reversed motor neuron disease using stem-cell therapy!
0:04:26 > 0:04:28It's incredible!
0:04:28 > 0:04:31He almost had me until he compared the guy to Christ.
0:04:31 > 0:04:33Did you guys just watch what I've just watched?
0:04:33 > 0:04:35Cos what I saw was amazing.
0:04:35 > 0:04:37Is he really coming here?
0:04:37 > 0:04:39- Something else, isn't it? - It really is.
0:04:39 > 0:04:41Who knew you could change the future of medicine with
0:04:41 > 0:04:43a face that symmetrical?
0:04:43 > 0:04:46Well, I've heard about it before, but seeing it is...
0:04:46 > 0:04:48Going to be some ride, I promise you that.
0:04:52 > 0:04:55Blimey. I had less stuff when I moved an entire life
0:04:55 > 0:04:56and four kids across town.
0:04:56 > 0:04:57An embarrassment.
0:04:57 > 0:05:00Whole hospital in meltdown about a few expensive toys
0:05:00 > 0:05:01and a flashy title.
0:05:01 > 0:05:03Director of Surgical Innovation.
0:05:03 > 0:05:06Hanssen dancing around Oompa Loompas like a child who's just found
0:05:06 > 0:05:09out Willy Wonka's coming to stay.
0:05:09 > 0:05:10Genius confectioner though he was,
0:05:10 > 0:05:13I'm pretty sure Willy Wonka never made a man walk again though,
0:05:13 > 0:05:15- did he?- I'll take your word for it.
0:05:15 > 0:05:17It's hard not to get excited that he chose here.
0:05:17 > 0:05:19Though I can see you're giving it your best shot.
0:05:19 > 0:05:22And I suppose you stopped to ask yourself why he's chosen here?
0:05:24 > 0:05:26What are you waiting for, a formal invitation?
0:05:26 > 0:05:28Our paths haven't crossed much this week
0:05:28 > 0:05:30and I just wanted to see if you're OK, all right?
0:05:30 > 0:05:33- Cos the last time... - Save it for your bedside diary.
0:05:33 > 0:05:34I meant, what have you got for me?
0:05:34 > 0:05:37Some of us have surgical innovations to be getting on with.
0:05:37 > 0:05:39That is the blanket term now, I presume?
0:05:39 > 0:05:43I have a preliminary report on Mrs Khan that needs your signature.
0:05:49 > 0:05:51OK?
0:05:51 > 0:05:52I need to read it through.
0:05:54 > 0:05:58Course. And Professor Gaskell's team called ahead.
0:05:58 > 0:05:59They're bringing a patient with them.
0:05:59 > 0:06:03Spindle cell tumour with an intrathoracic vascular supply.
0:06:03 > 0:06:05Obviously he needs you in theatre with him.
0:06:05 > 0:06:07Asked for you specifically.
0:06:07 > 0:06:09Well, here's an idea - why not open with that?!
0:06:12 > 0:06:15Whatever. Just get them to send me the details.
0:06:27 > 0:06:28You knew.
0:06:28 > 0:06:30- I did not.- I think you did.
0:06:30 > 0:06:33And judging by Donna's hot flush at his imminent arrival, I think
0:06:33 > 0:06:36you tied me down to your bourgeois dream in case I got any ideas.
0:06:36 > 0:06:38You got all this without even watching
0:06:38 > 0:06:40this morning's propaganda message?
0:06:40 > 0:06:42Might just be the way you're delivering it,
0:06:42 > 0:06:43but am I sensing some jealousy here?
0:06:43 > 0:06:46Am I the only one who remembers all the cutting-edge science
0:06:46 > 0:06:48we do here on a daily basis?
0:06:48 > 0:06:52What, by patching up the levee and praying the rains don't come?
0:06:52 > 0:06:54I'm not suggesting the professor
0:06:54 > 0:06:56is bringing a broom to this system - thank you -
0:06:56 > 0:06:59but it is an opportunity to impress an impressive person.
0:06:59 > 0:07:01Is this all before or after you've fallen at his feet
0:07:01 > 0:07:04- and proposed your affair? - SHE SCOFFS
0:07:04 > 0:07:07He reversed motor neuron disease using stem-cell treatment!
0:07:07 > 0:07:09Allegedly.
0:07:09 > 0:07:12That is the medical equivalent of landing on the moon!
0:07:12 > 0:07:14All I'm saying is, once you've been to space,
0:07:14 > 0:07:16the chances are you're going to want to go back.
0:07:16 > 0:07:19And you think I should go with him?
0:07:19 > 0:07:20Someone's going to.
0:07:20 > 0:07:23Three Cabgs, one AVR and a Vats lobe in one day?
0:07:23 > 0:07:26I thought you began every morning begging for a new challenge.
0:07:26 > 0:07:27Tests of skill, not of will power.
0:07:27 > 0:07:29Well, prove you have the latter and the rest will follow.
0:07:29 > 0:07:32All these years later and I'm still at the "prove it" stage with you.
0:07:32 > 0:07:33What other stage is there?
0:07:33 > 0:07:35Yet, if I'm going to take the entire list,
0:07:35 > 0:07:37what exactly does that leave you with?
0:07:37 > 0:07:41Intrathoracic vascular isolation and resection of spindle cell tumour
0:07:41 > 0:07:46with implantation of spinal progenitor matrix. Huh!
0:07:46 > 0:07:50So, the boss hooked the big one, eh? The great Professor Gaskell.
0:07:50 > 0:07:52I'm sorry, who are you?
0:07:52 > 0:07:54This is Ms MacMillan's husband, the eminent David Hopkins.
0:07:54 > 0:07:56David's here for Ms MacMillan's project...
0:07:56 > 0:07:58David, this is...
0:07:58 > 0:07:59You know Gaskell?
0:07:59 > 0:08:03Know him? Man introduced me to this one many moons ago.
0:08:03 > 0:08:05She has him to blame.
0:08:05 > 0:08:06Hope you don't mind -
0:08:06 > 0:08:09Roxanna let me have a sneak preview of the case.
0:08:09 > 0:08:11He's nothing if not persistent.
0:08:11 > 0:08:12Going to need ice in those veins.
0:08:12 > 0:08:15Trust me, if anyone's cold enough...
0:08:15 > 0:08:16Don't you have an AVR to attend to?
0:08:16 > 0:08:18And a very steady hand.
0:08:20 > 0:08:21Which theatres are free?
0:08:21 > 0:08:23- None of them. We're back-to-back. Why?- Every ward?
0:08:23 > 0:08:26All squeezed to make room for the King and Queen.
0:08:27 > 0:08:29Page me the second he gets here.
0:08:29 > 0:08:31But I'll be in...
0:08:31 > 0:08:33theatre.
0:08:33 > 0:08:34I heard he walks everywhere.
0:08:34 > 0:08:37Pretty sure Hanssen said he's arriving by car.
0:08:37 > 0:08:39Why would you, though, if you had a plane?
0:08:39 > 0:08:43Apparently he likes those long night-time city strolls.
0:08:43 > 0:08:45He's not Jack the Ripper, Lofty.
0:08:45 > 0:08:48I'd go by helicopter. I think it makes a statement.
0:08:48 > 0:08:50He's flying from Europe, I'm not sure a helicopter can...
0:08:50 > 0:08:52Actually, how far can a helicopter fly?
0:08:52 > 0:08:54Am I standing too straight? I feel like I'm standing too straight.
0:08:54 > 0:08:57- Honestly, would you lot chill yourselves?- I think he's here.
0:08:57 > 0:09:01- What's this?- Does my hair look all right?- Yeah.- OK, great.- Is this him?
0:09:01 > 0:09:03SIREN WAILS
0:09:03 > 0:09:05Ugh, you are kidding!
0:09:05 > 0:09:06Where is he?
0:10:04 > 0:10:06Never one for surprises.
0:10:06 > 0:10:08How long are you going to leave it before you tell them
0:10:08 > 0:10:09that he's slipped right by?
0:10:11 > 0:10:12Fresh air will do them good.
0:10:14 > 0:10:18Would you care to join me in greeting our esteemed new colleague?
0:10:18 > 0:10:20Oh, he'll find us when he's ready.
0:10:22 > 0:10:24He's coming here because of you, Henrik,
0:10:24 > 0:10:26and this team.
0:10:26 > 0:10:27Because of what you fostered.
0:10:27 > 0:10:29That's what this buzz is about.
0:10:51 > 0:10:53Mr Di Lucca, need you here, please!
0:10:56 > 0:10:57Bloke hauled her out of a frozen lake.
0:10:57 > 0:11:00- We've given her around ten shocks. She's still in VF.- Core temperature?
0:11:00 > 0:11:02- 25.- That's too low.
0:11:02 > 0:11:05If we can't get a regular rhythm, we'll have to get her on Ecmo.
0:11:05 > 0:11:07Can we get a warming blanket and I'll get the Ecmo kit?
0:11:07 > 0:11:09- Do not stop massaging that heart! - How did it happen?
0:11:09 > 0:11:13No idea. ED are chasing the police, I'm chasing the medical notes.
0:11:13 > 0:11:15She's not shivering. That's not good.
0:11:15 > 0:11:17Yeah, well, this one cost me a front-row seat at the meet-and-greet
0:11:17 > 0:11:20with Professor Marvellous, so she needs to pull through.
0:11:20 > 0:11:23- Full recovery, please. - He's here?- No idea.
0:11:23 > 0:11:24Doors opening.
0:11:31 > 0:11:32Doors closing.
0:11:35 > 0:11:36METALLIC RATTLING
0:11:53 > 0:11:56Something so visceral about this place, isn't there?
0:11:56 > 0:11:58Cage-lined walk to an illicit chamber.
0:12:05 > 0:12:09I suppose they only told you about the cardiac element this morning,
0:12:09 > 0:12:12but, if you're anything like me, less time to worry about the
0:12:12 > 0:12:14outcomes is probably the best way, don't you find?
0:12:16 > 0:12:19I really need to trust these student doctors more.
0:12:20 > 0:12:21Letting go of control.
0:12:21 > 0:12:24Impossible in our game, isn't it?
0:12:24 > 0:12:27Well, look forward to dancing together.
0:12:38 > 0:12:39Femoral artery's in.
0:12:39 > 0:12:42Femoral vein...and we are good.
0:12:42 > 0:12:43Shall we give her bicarb?
0:12:43 > 0:12:45No need. Acidic PH protects at a low temperature.
0:12:45 > 0:12:47Get the Bair Hugger started.
0:12:48 > 0:12:50Essie?
0:12:50 > 0:12:51She's pregnant.
0:12:52 > 0:12:54Right, let's give her some heparin.
0:12:54 > 0:12:56It's a go on the Ecmo, let's start warming her up fast.
0:12:56 > 0:12:57Raf, she's pregnant!
0:12:57 > 0:13:00- The chances of a major bleed on Ecmo are high.- Less than 50%.
0:13:00 > 0:13:03- We can't take her off now. - She might go into premature labour.
0:13:03 > 0:13:05- The mother has to be our concern. - Retroplacental bleed!
0:13:05 > 0:13:08The mother is our concern! It's the best that we can do!
0:13:08 > 0:13:10Rosie Cranham's notes! She's pregnant!
0:13:10 > 0:13:11- We know!- We know!
0:13:11 > 0:13:12With twins.
0:13:14 > 0:13:16You were supposed to page me when he arrived.
0:13:16 > 0:13:18Can I help you?
0:13:18 > 0:13:20What stage are you at?
0:13:20 > 0:13:22This is the AVR that you asked me to do for you.
0:13:22 > 0:13:25Again, not what I asked. I said, what stage? Just move.
0:13:25 > 0:13:27I'm just about to make the first cut. I'm sorry, what?
0:13:27 > 0:13:29- I'm taking over. - What do you think you're doing?
0:13:29 > 0:13:32I don't have time for your brain to catch up with your feet. Move.
0:13:32 > 0:13:35Do you remember the part where I signed up to today's entire list
0:13:35 > 0:13:37so that you could focus on the glitz and glamour of...
0:13:37 > 0:13:41I signed you up to the entire list and I'm letting you go!
0:13:41 > 0:13:42OK, just to be clear, are you going
0:13:42 > 0:13:44to do this with every procedure today?
0:13:44 > 0:13:46You know, there's a reason you haven't progressed the way
0:13:46 > 0:13:49you should have done, Valentine, because you don't have the mettle,
0:13:49 > 0:13:52the drive, the ability. None of it.
0:13:52 > 0:13:55But most of all, it's because you constantly fail
0:13:55 > 0:13:57to remember that you work for me!
0:13:57 > 0:14:00I decide where you go and what you do.
0:14:00 > 0:14:02I own you.
0:14:02 > 0:14:06And until you get that, you will never, ever, have even
0:14:06 > 0:14:07the slightest chance of saving,
0:14:07 > 0:14:10let alone enhancing, your pathetic excuse for a career.
0:14:12 > 0:14:14Status is something you earn.
0:14:45 > 0:14:486/0 prolene, please. Let's start grafting.
0:14:53 > 0:14:55Oi! I just took the stairs!
0:14:55 > 0:14:57I thought you said he was on the stairwell.
0:14:57 > 0:14:59He must have come up the back lift.
0:14:59 > 0:15:00So he's here, then?
0:15:08 > 0:15:10Right, so what? They're all friends?
0:15:10 > 0:15:13All four of them apparently. Rigden University.
0:15:13 > 0:15:16Imagine that, these four young prodigies together in America
0:15:16 > 0:15:19and all these years later, here they are, together again.
0:15:19 > 0:15:21Just trying to imagine Hanssen as a student,
0:15:21 > 0:15:23eating cheese burgers and chain-smoking.
0:15:24 > 0:15:25Anyway, how do you know this?
0:15:25 > 0:15:28And what are you doing up here on Keller stalking them?
0:15:28 > 0:15:31David had a copy of the notes and offered to let me have a look.
0:15:31 > 0:15:34Oh, David is it now? Well, haven't you done well.
0:15:34 > 0:15:36Apparently the professor left this with us.
0:15:36 > 0:15:38He's wondering if we could get some Blu Tack to stick it up
0:15:38 > 0:15:41- outside his lab. - All right. Well, I can do that.
0:15:41 > 0:15:44- It's very precious apparently, so... - All right, chill out.- Just saying!
0:15:46 > 0:15:47It's half-finished.
0:15:47 > 0:15:49All the best art is.
0:15:49 > 0:15:52It's probably a worth a fortune. I can look after it, if you like.
0:15:52 > 0:15:53No. You need to chill out as well.
0:15:53 > 0:15:55I think I can find some Blu Tack, thank you.
0:15:58 > 0:16:00I've missed you, my old friend.
0:16:02 > 0:16:03All of you.
0:16:05 > 0:16:06Well, we've been aware of you.
0:16:06 > 0:16:09Yes, rather a splendid achievement, if I may say so.
0:16:09 > 0:16:11Luck. Hard work and luck.
0:16:11 > 0:16:13Nothing to do with it. Either of them.
0:16:13 > 0:16:17Well, if it hadn't have been me, it would have been one of you.
0:16:17 > 0:16:20Oh, no, it was always going to be you, John.
0:16:20 > 0:16:22You finally did it.
0:16:22 > 0:16:24Full motor neuron reversal.
0:16:24 > 0:16:28So, come on - tell us what we're all burning to know, Professor Gaskell.
0:16:29 > 0:16:31Can it be done again?
0:16:32 > 0:16:34I'm close.
0:16:35 > 0:16:38I'm sorry to interrupt. Professor, your patient has arrived.
0:16:38 > 0:16:39He collapsed en route.
0:16:40 > 0:16:41Excuse me.
0:16:43 > 0:16:44Professor Gaskell, I'm Mr Valentine.
0:16:44 > 0:16:46I'm afraid Ms Naylor is tied up in theatre.
0:16:46 > 0:16:49- You're her number two. - I wouldn't say that.
0:16:49 > 0:16:51Patient's autonomic system has shut down due to
0:16:51 > 0:16:52compression of the spinal cord.
0:16:52 > 0:16:54He's profoundly shocked, hypotensive.
0:16:54 > 0:16:56Will that affect his treatment?
0:16:56 > 0:16:58Only if we let it.
0:16:58 > 0:17:00Give him two litres of plasma expander
0:17:00 > 0:17:01and a starting infusion of norad.
0:17:01 > 0:17:030.2 micrograms per kilo, per minute.
0:17:12 > 0:17:13I took a glance at the notes.
0:17:13 > 0:17:17You're using a tissue scaffold laced with stem cells?
0:17:17 > 0:17:19Progenitor cells, to grow back the part we're taking from him.
0:17:19 > 0:17:22How on earth do you go about getting approval for something like that?
0:17:22 > 0:17:26Well, first, you have to make a man walk again.
0:17:26 > 0:17:27Doors opening.
0:17:28 > 0:17:30Sorry, I-I-I just meant,
0:17:30 > 0:17:32if those cells have been treated with growth factor...
0:17:32 > 0:17:33Let's talk some other time.
0:17:33 > 0:17:36I hear you have ideas to pitch. My door is open.
0:17:36 > 0:17:38Thank you.
0:17:38 > 0:17:40David?
0:17:40 > 0:17:43Surprised you're not getting in on this too, Mr Valentine.
0:17:43 > 0:17:45A chance for us all to witness the future first hand.
0:17:47 > 0:17:50- You're here for the project, though? - Sorry?
0:17:50 > 0:17:52Ms MacMillan's project, the VR simulator.
0:17:52 > 0:17:54Oh, she gave up on that.
0:17:54 > 0:17:57Turns out I'm not such a viable candidate after all.
0:17:57 > 0:18:00Though, to be honest, how can she be expected to focus
0:18:00 > 0:18:04when her old friend comes jetting in with this kind of challenge?
0:18:05 > 0:18:08Trust me, she'd be the first to say it.
0:18:09 > 0:18:11There's only one team to be on now.
0:18:17 > 0:18:20As soon as they are done, can you run an EEG on the mother?
0:18:20 > 0:18:21If there's no brain activity,
0:18:21 > 0:18:23then we have to make a decision about the foetuses.
0:18:23 > 0:18:25- Fine.- You OK?
0:18:28 > 0:18:29I don't know. I'm sorry.
0:18:29 > 0:18:31Hey, hey, hey. Come on, in here.
0:18:34 > 0:18:35What's going on?
0:18:35 > 0:18:37I don't know, I just feel strange.
0:18:38 > 0:18:42It's like, the professor arrives and I suggest that you do something to
0:18:42 > 0:18:46- impress him and then suddenly we need Ecmo.- And?
0:18:46 > 0:18:48Well, you introduced Ecmo to the hospital.
0:18:48 > 0:18:49Don't you think that's weird?
0:18:49 > 0:18:51I never made the link.
0:18:51 > 0:18:53And then there are twins. Kim had twins.
0:18:53 > 0:18:55Essie, what are you saying?
0:18:55 > 0:18:57I'm just really worried!
0:18:57 > 0:18:58I can't explain it.
0:18:58 > 0:19:00It's like someone's trying to tell me something.
0:19:02 > 0:19:06Right, well, maybe just trust the science, not superstition.
0:19:06 > 0:19:09I know what I'm doing.
0:19:09 > 0:19:11She will be OK, so will the babies.
0:19:11 > 0:19:13KNOCK ON DOOR
0:19:13 > 0:19:15Hi, I'm so sorry to disturb you,
0:19:15 > 0:19:18but I think there's something you should come and see.
0:19:18 > 0:19:22Having quite the time of it today, David, isn't he?
0:19:22 > 0:19:24- It's like he's never been away. - Yes, he's been looking forward to...
0:19:24 > 0:19:27Wasn't quite sure what to make of it when he told me.
0:19:27 > 0:19:29- Told you?- You're not going to deny it, are you?
0:19:29 > 0:19:31You know what I'm talking about. Your little video game solution!
0:19:31 > 0:19:33Your project! The project I gave you!
0:19:33 > 0:19:35The project your husband tells me you abandoned
0:19:35 > 0:19:37- because he isn't even a viable candidate.- I...
0:19:37 > 0:19:39Yes, I abandoned it, but...
0:19:39 > 0:19:41You said nothing when I mentioned it earlier.
0:19:41 > 0:19:44I'm sorry, I'm not sure I understand what you want.
0:19:44 > 0:19:46OK, well, here's a thought out of left field -
0:19:46 > 0:19:49how about the tiniest sliver of respect for who I am and what I do?!
0:19:53 > 0:19:55- Mr Valentine, can I speak to you? - Not now.
0:19:55 > 0:19:57It's Professor Hopkins.
0:19:58 > 0:20:00Do you think he's OK?
0:20:00 > 0:20:02Only I tried to ask for the notes earlier on and he stumbled.
0:20:02 > 0:20:04There was nobody around him.
0:20:04 > 0:20:05He just brushed it off.
0:20:05 > 0:20:08Yes, well, turns out he may be a lot more lucid than
0:20:08 > 0:20:10you may have been led to believe by Ms MacMillan.
0:20:10 > 0:20:13- PAGER BEEPS - No, it was more the way he reacted, like he was embarrassed.
0:20:13 > 0:20:14That's because he fell.
0:20:14 > 0:20:17One of the nurses said she saw the same thing happen earlier.
0:20:17 > 0:20:18He was getting angrier.
0:20:21 > 0:20:25Nurse Chiltern, please, just get on with whatever it is you need to do.
0:20:25 > 0:20:26Today is...
0:20:32 > 0:20:35- A third heartbeat. - I don't understand how it could have happened.- It's much smaller...
0:20:35 > 0:20:37They must have missed it on her 20-week scan.
0:20:37 > 0:20:40The little thing must have been hiding behind one of the others.
0:20:40 > 0:20:41- So this is...- Triplets.
0:20:41 > 0:20:44- Looks like superfoetation. - Super-come-what-now?
0:20:44 > 0:20:47Superfoetation. It means she got pregnant whilst already pregnant.
0:20:47 > 0:20:48It's rare. Like, so rare.
0:20:48 > 0:20:51- Like, one in a million rare. - So this is a miracle baby?
0:20:55 > 0:20:59Sacha, have you seen Jac? She's supposed to be with Gaskell, but...
0:20:59 > 0:21:00All right, all right.
0:21:00 > 0:21:03Before you start going on about me wasting NHS resources,
0:21:03 > 0:21:06I did it on my break.
0:21:06 > 0:21:08I swapped the frame with some disgusting painting
0:21:08 > 0:21:11I found on Paeds. I'll get them another one.
0:21:11 > 0:21:13Anyway, it's starting to grow on me.
0:21:13 > 0:21:16Think I'm starting to see what it represents.
0:21:16 > 0:21:18That fact that it's unfinished is...
0:21:18 > 0:21:19I'm sure he'll love it.
0:21:19 > 0:21:20Cool.
0:21:23 > 0:21:26What do you mean, she's supposed to be with Gaskell?
0:21:26 > 0:21:27Oliver, with me.
0:21:29 > 0:21:31Actually, I wanted to talk to you first and now seems
0:21:31 > 0:21:34like as good a time as any to inform you that I think you're right.
0:21:34 > 0:21:37You've done absolutely nothing for me, clearly never plan to,
0:21:37 > 0:21:39and while usually that feeds me with sufficient ammunition for a
0:21:39 > 0:21:42Friday night spent alone cleaning my bathroom and guzzling gin,
0:21:42 > 0:21:43I feel empty.
0:21:44 > 0:21:46Here. I'm not having any fun.
0:21:46 > 0:21:47Haven't we been here before?
0:21:47 > 0:21:50An apology from you is the last thing I expect.
0:21:50 > 0:21:52Or care about. But you have to acknowledge my resignation.
0:21:52 > 0:21:54- Is it in writing?- It will be.
0:21:56 > 0:21:57What is this?
0:21:57 > 0:21:59A test of skill over willpower or whatever you coined.
0:21:59 > 0:22:01- Have a seat.- I'm serious.
0:22:01 > 0:22:03Not serious enough. That's part of the problem.
0:22:06 > 0:22:10Which artery comes off the aorta to supply the spinal cord with blood,
0:22:10 > 0:22:11and why focus on it?
0:22:14 > 0:22:16Jac, my plan is to finish the day here and then...
0:22:16 > 0:22:18Just sit down!
0:22:29 > 0:22:31The artery of Adamkiewicz.
0:22:31 > 0:22:34You have to make sure that the graft doesn't occlude
0:22:34 > 0:22:36the outflow from that vessel.
0:22:38 > 0:22:41So you'd just go ahead with this kind of experimental implant?
0:22:41 > 0:22:43I'd want to see the entire clinical trial timeline.
0:22:43 > 0:22:45I'd want certification from approved boards.
0:22:45 > 0:22:47I'd want to know who I was dealing with.
0:22:47 > 0:22:48See where the tissue came from.
0:22:48 > 0:22:51And with the stakes this high, I'd want re-assurances...
0:22:51 > 0:22:52It's not about him.
0:22:52 > 0:22:54I'd want more re-assurances than just one man's word!
0:22:54 > 0:22:56You're missing the point.
0:23:01 > 0:23:03You think it should be delayed.
0:23:04 > 0:23:06Is that what you think?
0:23:10 > 0:23:12I think you owe me an apology.
0:23:15 > 0:23:16OK, have it your way.
0:23:23 > 0:23:24You're afraid.
0:23:25 > 0:23:28And I'd go as far as to say, for some reason, you're terrified,
0:23:28 > 0:23:31but I won't be your escape clause.
0:23:31 > 0:23:33I give you one chance and you blow it.
0:23:33 > 0:23:36Your arrogance astounds me, but your stupidity is breathtaking.
0:23:49 > 0:23:51Tumour is in the spinal canal
0:23:51 > 0:23:55and circling the aorta, causing paralysis and extreme weakness.
0:23:55 > 0:23:57Been suffering excruciating back pain
0:23:57 > 0:24:00and no sensation at all in this leg.
0:24:00 > 0:24:02- Correct, Michael?- Yeah.
0:24:02 > 0:24:06The scaffold will be 3D printed, laced with stem cells, trimmed
0:24:06 > 0:24:09to size and once the tumour has been removed safely, inserted...
0:24:09 > 0:24:12Sorry, and this will then grow back the part that you've
0:24:12 > 0:24:13removed from the patient?
0:24:13 > 0:24:16If I'm not mistaken, you're suggesting the spine will
0:24:16 > 0:24:19also have enhanced regenerative properties after injury?
0:24:19 > 0:24:20Correct.
0:24:20 > 0:24:23- Can I ask about the make-up of the cells? I mean...- Ms Naylor.
0:24:23 > 0:24:26Gaskell has just been filling us in on the future of medicine.
0:24:26 > 0:24:27Ms Naylor, of course, will be...
0:24:27 > 0:24:30Ms Naylor will be performing the only role that matters.
0:24:30 > 0:24:32Unless the real surgery gets done,
0:24:32 > 0:24:33nobody gets to play with any new toys.
0:24:33 > 0:24:35I'll need to see the aortogram and a contrast CT.
0:24:35 > 0:24:38I want to see the feeding vessels to this tumour
0:24:38 > 0:24:40if I have to isolate it. And as lead surgeon on this,
0:24:40 > 0:24:43I'll need access to my own team and equipment.
0:24:43 > 0:24:46The operation will take place in my theatre on Darwin Ward.
0:24:46 > 0:24:48I suggest you get him prepped.
0:24:53 > 0:24:54Sorry about that.
0:24:54 > 0:24:56It's been a very tricky time with the merger.
0:24:56 > 0:24:59Everyone is very tense. She's not normally like that.
0:24:59 > 0:25:02With what she's been through, I'm surprised she's even functioning.
0:25:02 > 0:25:03I'm not sure I'd be.
0:25:03 > 0:25:05Sorry, I don't know what you mean.
0:25:05 > 0:25:06She lost her sister.
0:25:08 > 0:25:09We all did.
0:25:11 > 0:25:13Her core temperature is increasing lactates
0:25:13 > 0:25:16- and she's cardiovascularly stable. - That's great.
0:25:16 > 0:25:19Urine output is much better, so she's well perfused.
0:25:19 > 0:25:20Told you it was all under control.
0:25:21 > 0:25:23Ess?
0:25:23 > 0:25:27My ring. I don't know where it is.
0:25:27 > 0:25:29OK, well, maybe you just left it somewhere.
0:25:29 > 0:25:30I've checked everywhere.
0:25:30 > 0:25:33And there was me thinking marriage was just a bourgeois conceit.
0:25:33 > 0:25:37Raf! I told you today was... Just forget it.
0:25:37 > 0:25:40Look, the patient is getting better. The babies are going to be fine.
0:25:40 > 0:25:43You've just lost a ring. I can help you look for it.
0:25:43 > 0:25:45We can retrace your steps.
0:25:45 > 0:25:48I know we risk losing people every day, but superfoetation?
0:25:48 > 0:25:50When do you hear of that?
0:25:50 > 0:25:51I mean, you might have seen it,
0:25:51 > 0:25:53but I haven't and this is not superstition.
0:25:53 > 0:25:57- It's not me.- I never said it was. I said to trust the science.
0:25:57 > 0:25:58Trust Ecmo.
0:25:58 > 0:26:01Well, you trust it, but... it's a risk.
0:26:01 > 0:26:03Ecmo's there to reduce risk.
0:26:03 > 0:26:06I'm not doing all this because I get some sort of a thrill from it.
0:26:06 > 0:26:08Aren't you? You don't get a buzz?
0:26:08 > 0:26:11I understand, you're bringing people back from the brink, but...
0:26:11 > 0:26:13That's not what Ecmo is for me. It's not a thrill.
0:26:13 > 0:26:16It's...it's control. It's something I can trust.
0:26:16 > 0:26:19It's the way that where limitations stop most doctors,
0:26:19 > 0:26:21I get to carry on,
0:26:21 > 0:26:22operating outside the of the margins.
0:26:24 > 0:26:26Ecmo is your friend.
0:26:26 > 0:26:28Yeah, if you like.
0:26:28 > 0:26:31Ecmo is your life-affirming friend.
0:26:31 > 0:26:33Yes, exactly.
0:26:33 > 0:26:36Professor would like to see the real heroes of this place.
0:26:36 > 0:26:39And before you put your foot in it, Mr Di Lucca, that's us nurses.
0:26:39 > 0:26:40Come on.
0:26:40 > 0:26:43It'll turn up. Stop thinking it symbolises Armageddon.
0:27:16 > 0:27:18Hey.
0:27:21 > 0:27:22How are you doing?
0:27:29 > 0:27:30I'm looking into this miracle.
0:27:32 > 0:27:34Patient zero. Laszlo Furz of Hungary.
0:27:35 > 0:27:37Do you know the professor himself has Hungarian roots?
0:27:40 > 0:27:41He parades him around
0:27:41 > 0:27:45to the public, to the media, but it's so controlled.
0:27:45 > 0:27:47It's never to doctors nor trained medics.
0:27:49 > 0:27:52Has anyone exactly examined the patient zero, you know?
0:27:52 > 0:27:55Looked at the workings, had them verified?
0:27:56 > 0:27:58I'm not denying he made a man walk again.
0:27:58 > 0:28:00I mean, that's incredible, but...
0:28:00 > 0:28:02why keep him hidden away?
0:28:08 > 0:28:12Did I ever tell you that when I feel anxious about an operation,
0:28:12 > 0:28:15I practise my bloods triads in my head?
0:28:17 > 0:28:20This is Levy's triad of bleeding -
0:28:20 > 0:28:22all blood comes from cut blood vessels.
0:28:22 > 0:28:23All bleeding eventually stops.
0:28:56 > 0:28:59MACHINE WHIRS
0:29:14 > 0:29:15Come on in.
0:29:18 > 0:29:20Well, this is more than I had expected.
0:29:20 > 0:29:22Thank you.
0:29:22 > 0:29:24Look, I'll keep this brief, I know how busy you are,
0:29:24 > 0:29:28and this is exactly why it had to be you that saw this first.
0:29:28 > 0:29:31I hear there's been talk of flashy titles -
0:29:31 > 0:29:34Director of Surgical Innovation or something.
0:29:34 > 0:29:35You can just call me John,
0:29:35 > 0:29:39Professor Gaskell, whatever you normally use here.
0:29:39 > 0:29:41If I'm lucky, they'll paint me as solipsistic.
0:29:41 > 0:29:45Normally it hovers around the self-obsessed narcissist mark.
0:29:45 > 0:29:46I'm neither.
0:29:46 > 0:29:50I have no interest in myself, only the end goal.
0:29:50 > 0:29:53And anyone that can help me to achieve that
0:29:53 > 0:29:56or who functions with a similar obsessiveness, I admire deeply.
0:29:57 > 0:30:00But, look, I'm new to school.
0:30:00 > 0:30:01And every new kid needs a friend.
0:30:02 > 0:30:04Now, I know so many of you must have questions,
0:30:04 > 0:30:07so I thought it best just to show you first.
0:30:07 > 0:30:08I know what I need to do,
0:30:08 > 0:30:11and if you guys can continue to provide the environment that
0:30:11 > 0:30:14you do so immaculately...
0:30:14 > 0:30:16Professor, you do realise this hospital is falling apart
0:30:16 > 0:30:18at the seams, right?
0:30:18 > 0:30:20No, no, I'm not talking about what the Trust
0:30:20 > 0:30:22or what successive governments may have done.
0:30:22 > 0:30:26No, no, I'm talking about the fire behind your eyes,
0:30:26 > 0:30:28the smiles on your faces...
0:30:28 > 0:30:31Serious people that want to affect change,
0:30:31 > 0:30:33but want to have a good time along the way.
0:30:33 > 0:30:34THEY CHUCKLE
0:30:34 > 0:30:40My end, test tubes, stem cells - yours, hearts and minds.
0:30:40 > 0:30:43Don't think that I don't know about your concern for the numbers
0:30:43 > 0:30:47of clinical nursing staff retiring, Nurse Jackson,
0:30:47 > 0:30:50or your proposal to increase nurse staffing budgets, Nurse Harrison.
0:30:51 > 0:30:53As if that'd stick.
0:30:54 > 0:30:58This is simply my version of those.
0:31:00 > 0:31:02You have a new message. New messages...
0:31:04 > 0:31:10Henrik, I know what his arrival means to this place,
0:31:10 > 0:31:14and I know the size of the operation,
0:31:14 > 0:31:20but, I have to say, I'm concerned.
0:31:20 > 0:31:22I'm concerned about Jac.
0:31:22 > 0:31:24DISTANT SIREN WAILS
0:31:25 > 0:31:27She's not herself.
0:31:30 > 0:31:33I'm starting to wonder,
0:31:33 > 0:31:38you know, all this time she's been supporting me in my depression,
0:31:38 > 0:31:41I should have seen that she needed support too.
0:31:47 > 0:31:49I think you're going to be all right here.
0:31:49 > 0:31:52I like the feel of it already.
0:31:52 > 0:31:55Do you have a family of your own, John?
0:31:55 > 0:31:58There are people I care deeply about, yeah,
0:31:58 > 0:32:01and others I consider family, absolutely.
0:32:01 > 0:32:02Oh, is this yours?
0:32:02 > 0:32:05Yeah, it comes everywhere with me.
0:32:05 > 0:32:08First time it's ever been caged up in a frame, though.
0:32:08 > 0:32:11Oh, don't worry. I'll get the porters to sort it.
0:32:11 > 0:32:13No, no, I wouldn't want to insult whoever it was
0:32:13 > 0:32:16who went to all this trouble,
0:32:16 > 0:32:18but if it was to, say, break...
0:32:21 > 0:32:25Well, consider its shattering a catharsis of some kind,
0:32:25 > 0:32:27or a chaos, if you prefer.
0:32:27 > 0:32:29Don't worry, I'll clear up any mess.
0:32:34 > 0:32:36GLASS SMASHES
0:32:43 > 0:32:45HANDS SCRUBBING
0:32:49 > 0:32:51Nerves?
0:32:51 > 0:32:53I'm never nervous.
0:32:53 > 0:32:55Darwin Clinical Lead.
0:32:55 > 0:32:58Instigator of Holby City's stent trial programme,
0:32:58 > 0:33:00leader of cardiac trauma unit,
0:33:00 > 0:33:02performed several hemicorporectomies,
0:33:02 > 0:33:06an obscene amount of pulmonary endarterectomies...
0:33:06 > 0:33:09You pushed for the Herzig 5 when no-one else believed in it,
0:33:09 > 0:33:13and the first surgeon here to implement stem cell projects.
0:33:13 > 0:33:14So this...
0:33:14 > 0:33:16WATER SPLASHES
0:33:18 > 0:33:23I know my predecessor, Mr Self, performed a similar procedure.
0:33:23 > 0:33:25Successfully.
0:33:25 > 0:33:28What happened to him must have been tough.
0:33:28 > 0:33:30I'm not here to replace anyone.
0:33:36 > 0:33:38"The consequences of this will be severe,
0:33:38 > 0:33:39"but you've brought this on yourselves...
0:33:39 > 0:33:42Jeremy Warren. This is the second one today.
0:33:42 > 0:33:45The first one said something about the red-haired doctor.
0:33:45 > 0:33:47Jac? What's this got to do with Ja...?
0:33:47 > 0:33:49ROSIE GROANS Raf.
0:33:49 > 0:33:52Rosie? Rosie, can you hear me?
0:33:52 > 0:33:54ROSIE MOANS Rosie, my love.
0:33:54 > 0:33:55Can you tell me where it hurts?
0:33:55 > 0:33:57Long hard contractions.
0:33:57 > 0:33:59Right, these babies are coming, my love, OK?
0:33:59 > 0:34:00Need to check but possibly.
0:34:00 > 0:34:02The shock of the hypothermia must have triggered labour.
0:34:02 > 0:34:04- Where's that CTG monitor? - Erm, I don't know, I...
0:34:04 > 0:34:07Oh, Terry, thank you.
0:34:07 > 0:34:08- OK...- I'll need to check the cervix.
0:34:08 > 0:34:10Who's this?
0:34:10 > 0:34:14This is Ezra. The police found him looking for his mum.
0:34:14 > 0:34:15I don't believe this.
0:34:15 > 0:34:16We'll come back.
0:34:18 > 0:34:19Mummy's going to be fine,
0:34:19 > 0:34:21but the doctors need to look at her and the babies,
0:34:21 > 0:34:22so we're going to come back, OK?
0:34:22 > 0:34:24OK.
0:34:28 > 0:34:33Thoracotomy first, then identify the blood supply to the tumour.
0:34:33 > 0:34:35Insert the graft to bypass that area,
0:34:35 > 0:34:37and ligate the blood supply to the tumour.
0:34:37 > 0:34:40Once that's done, remove the part of the vertebral body over the
0:34:40 > 0:34:43tumour in order to access it,
0:34:43 > 0:34:47remove the tumour and put the implant in.
0:34:47 > 0:34:50The imperative to isolate the blood vessel properly
0:34:50 > 0:34:52cannot be stressed enough.
0:34:52 > 0:34:56Once the tumour has been excised from the aorta,
0:34:56 > 0:34:57well, we all know the risks...
0:34:57 > 0:34:59As ever, be decisive.
0:34:59 > 0:35:01MACHINE BEEPS STEADILY
0:35:14 > 0:35:16SHE TAKES A DEEP BREATH
0:35:20 > 0:35:23Raf! Emergency C-section on the bradycardic baby?
0:35:23 > 0:35:25- They're over 30 weeks. - Only just!
0:35:25 > 0:35:27If we do a C-section now,
0:35:27 > 0:35:29we'll have a better chance of having three live babies.
0:35:29 > 0:35:32We leave them in, the mother deteriorates and then what?
0:35:32 > 0:35:34What happened to your faith in the Ecmo?
0:35:34 > 0:35:35Keep the babies warm.
0:35:35 > 0:35:38If you bring Rosie in now, there's a chance of a huge bleed
0:35:38 > 0:35:40and potential hysterectomy!
0:35:40 > 0:35:42She's young - I'll try to avoid that.
0:35:42 > 0:35:44You might not have a choice!
0:35:44 > 0:35:45You trust me, don't you?
0:35:45 > 0:35:46Of course.
0:35:46 > 0:35:48Mr Di Lucca, the ultrasound is showing a bleed
0:35:48 > 0:35:50between the uterus and the placenta.
0:35:50 > 0:35:51- Abruption?- Mm-hmm.
0:35:51 > 0:35:53Right, well, can we get an IV bolus of oxytocin
0:35:53 > 0:35:56and 800 micrograms of misoprostol into her, please?
0:35:56 > 0:35:57Sure, do you want me to scrub in?
0:35:57 > 0:35:59You don't have to do the caesarean hysterectomy.
0:35:59 > 0:36:01No. No, it's fine.
0:36:01 > 0:36:03It can't be the only option!
0:36:08 > 0:36:10How are they doing?
0:36:10 > 0:36:12- Too early to say.- Yeah.
0:36:12 > 0:36:14How about you? Everything OK?
0:36:14 > 0:36:19Fine. I just wish I was in there.
0:36:19 > 0:36:22It must be strange watching the two of them operate together
0:36:22 > 0:36:25after all this time, like being back at college...
0:36:25 > 0:36:27But I have to admit, the more I read about what this is,
0:36:27 > 0:36:29the more I'd like to be in there too.
0:36:32 > 0:36:34Professor Hopkins?
0:36:34 > 0:36:39It was at university that you met your...wife and Gaskell, right?
0:36:39 > 0:36:41Who is this guy?
0:36:41 > 0:36:42It's Mr Valentine.
0:36:44 > 0:36:45Valentine, eh?
0:36:55 > 0:36:58HE BREATHES HEAVILY
0:36:58 > 0:37:00What...? What are we watching?
0:37:00 > 0:37:03It's all right. I've got this.
0:37:06 > 0:37:09Ms Macmillan. It's David.
0:37:09 > 0:37:10Go. We'll be fine.
0:37:10 > 0:37:12This bit's sticking.
0:37:12 > 0:37:14- MACHINE CHIMES - BP is dropping. Bleed! Huge bleed!
0:37:14 > 0:37:17- Packs, please. - Ms Macmillan, go, please!
0:37:17 > 0:37:19I need some help here.
0:37:19 > 0:37:21EQUIPMENT HISSING
0:37:23 > 0:37:26OK, there's too much blood. Let's have an aortic clamp, please.
0:37:26 > 0:37:28He didn't recognise me, then he didn't know where he was,
0:37:28 > 0:37:33Nurse Chiltern saw him collapse and I dismissed it... I'm sorry.
0:37:33 > 0:37:35- Don't apologise. - I don't know what I was thinking.
0:37:35 > 0:37:37My head... Well, there's no excuse for it.
0:37:37 > 0:37:40I don't know why I doubted you or David's condition
0:37:40 > 0:37:41and the severity of it...
0:37:41 > 0:37:43- It's not your fault. - Yes, it is.
0:37:43 > 0:37:45I jumped to a false conclusion based on my own dented ego
0:37:45 > 0:37:46and my need to...
0:37:46 > 0:37:50I haven't been honest.
0:37:50 > 0:37:53I haven't been honest with him.
0:37:53 > 0:37:56I told him he wasn't eligible for the project,
0:37:56 > 0:38:00that his decline wasn't as severe as we first thought,
0:38:00 > 0:38:04and suggested he was getting better.
0:38:04 > 0:38:07He can remember in great detail operations he's done before,
0:38:07 > 0:38:09recall the most obscure medical dialect,
0:38:09 > 0:38:15like the language of his workplace keeps him energised, young,
0:38:15 > 0:38:17so I wanted him here,
0:38:17 > 0:38:18where I could see him, of course,
0:38:18 > 0:38:22but because it's where he's at his best.
0:38:25 > 0:38:26The best David.
0:38:29 > 0:38:32I abandoned the project for false hope.
0:38:32 > 0:38:33Selfish, isn't it?
0:38:33 > 0:38:38Roxanna, you know it's more complicated than that.
0:38:38 > 0:38:40His speech has slurred. I think he's having a stroke.
0:38:46 > 0:38:48MACHINE BEEPS
0:38:53 > 0:38:59OK, as soon as the aortic graft is stitched
0:38:59 > 0:39:03I can begin the hemivertebrectomy.
0:39:03 > 0:39:06I'll need a 5mm diamond burr and some rongeurs.
0:39:08 > 0:39:09Ms Naylor?
0:39:16 > 0:39:18Send someone for the scaffold, please -
0:39:18 > 0:39:20it needs to be here in the next ten minutes.
0:39:25 > 0:39:29I need some Floseal, clotting activator, and a Caspar retractor.
0:39:29 > 0:39:30Quickly, please.
0:39:30 > 0:39:33Ms Naylor, let me know when you've stitched.
0:39:39 > 0:39:43I...I can't do this. It's not going to work.
0:39:47 > 0:39:49Take over.
0:39:53 > 0:39:56It's not right. What you're doing is not right.
0:39:56 > 0:39:57- You are shaking... - I am fine!
0:39:57 > 0:40:00Why is everyone assuming there is something wrong with me today?
0:40:00 > 0:40:01I am questioning your methods -
0:40:01 > 0:40:03do not make this into something else.
0:40:03 > 0:40:04I feel no need to advertise myself...
0:40:04 > 0:40:06Which makes you truly ethical?
0:40:06 > 0:40:07If you like, yeah.
0:40:07 > 0:40:09You are feeding on their uncertainty.
0:40:09 > 0:40:12See, I think you understand that we live the same paradox.
0:40:12 > 0:40:13You want disorder, you need it -
0:40:13 > 0:40:16because, like me, you see coherence that way.
0:40:16 > 0:40:18- You need me! - I need your skills, yeah.
0:40:18 > 0:40:21You need me to trust you, and I'm sorry, but I don't know you...
0:40:21 > 0:40:23No, wrong. I don't need you to trust me.
0:40:23 > 0:40:25I need you to doubt everything I do, to criticise and interrogate
0:40:25 > 0:40:27all of it, like clarity is an ending
0:40:27 > 0:40:29and uncertainty is the purest thing we have!
0:40:29 > 0:40:31But for the rest of them, yes, I need your endorsement!
0:40:31 > 0:40:33I haven't got the time for them to catch up.
0:40:33 > 0:40:38I need them to see it first-hand - witness what this can do!
0:40:38 > 0:40:41You need them to witness what you can do.
0:40:41 > 0:40:43You have everything to lose.
0:40:43 > 0:40:45I know what you're going through.
0:40:45 > 0:40:47- Don't...- I've been to that place.
0:40:47 > 0:40:48I said don't!
0:40:48 > 0:40:50Then help me.
0:40:50 > 0:40:52I need them to see you finish. We both do.
0:40:52 > 0:40:53Professor Gaskell...
0:41:01 > 0:41:04DOOR SLAMS
0:41:04 > 0:41:05Where is she?
0:41:10 > 0:41:12WATER SPLASHES
0:41:12 > 0:41:14DOOR OPENS
0:41:32 > 0:41:34We need more blood! Six units!
0:41:34 > 0:41:36- MACHINE CHIMES - There's a bleed.
0:41:37 > 0:41:41Essie, I've been there -
0:41:41 > 0:41:45fallen for a case because I needed to somehow know the world
0:41:45 > 0:41:48still turned the way I was told.
0:41:48 > 0:41:50MACHINE BEEPS
0:41:50 > 0:41:52I've done two layers of suturing.
0:41:52 > 0:41:54- We'll have to do the hysterectomy. - No!
0:41:54 > 0:41:57Look, we'll stop the heparin infusion and do an ACT.
0:41:57 > 0:41:59I'll let it drop to 180.
0:42:00 > 0:42:04You can't attach meaning to this.
0:42:04 > 0:42:09It's not fair...on anyone.
0:42:09 > 0:42:12Whether the babies survive, whether the mother does...
0:42:12 > 0:42:14SHE TAKES A DEEP BREATH
0:42:14 > 0:42:18..the outcome is just that, an outcome.
0:42:21 > 0:42:23Yeah.
0:42:23 > 0:42:25I know.
0:42:25 > 0:42:27MACHINE CHIMES
0:42:30 > 0:42:31Come on.
0:42:37 > 0:42:42Inserting the stem cell scaffold into the space I've carved.
0:42:42 > 0:42:46Careful to mind the clip from the earlier bleed.
0:42:46 > 0:42:49BP is rising.
0:42:49 > 0:42:51Systemic reaction to the growth medium.
0:42:51 > 0:42:53He's having an immune response.
0:42:53 > 0:42:54We need to lower the blood pressure.
0:42:54 > 0:42:57Autonomic release of adrenaline. We need a GTN infusion, please.
0:42:57 > 0:42:59Let's get that pressure down.
0:43:04 > 0:43:06The clip's come off the artery.
0:43:06 > 0:43:09Ms Naylor, I need you to stitch.
0:43:09 > 0:43:10I'll cut the suture.
0:43:10 > 0:43:12MACHINE CHIMES
0:43:15 > 0:43:18He'll bleed out. Use your hand as a swab.
0:43:18 > 0:43:19Pledget.
0:43:26 > 0:43:28This is Naylor's triad of bleeding.
0:43:30 > 0:43:32All blood comes from vessels.
0:43:32 > 0:43:35All bleeding comes from cut vessels. All bleeding eventually stops.
0:43:35 > 0:43:37SHE SNIFFS
0:44:11 > 0:44:13WHEELS SQUEAK
0:44:40 > 0:44:42It's stopped. The bleed's stopped...
0:44:42 > 0:44:44Just hang on, hang on there a second...
0:44:48 > 0:44:50All the babies are OK.
0:44:50 > 0:44:55Rosie, did you manage to...? Is she OK?
0:44:55 > 0:44:57Yeah.
0:44:57 > 0:45:00So, mother and three babies.
0:45:03 > 0:45:05HE EXHALES It all worked out.
0:45:05 > 0:45:09- JAC:- This is Naylor's triad of bleeding.
0:45:09 > 0:45:11All blood comes from vessels.
0:45:11 > 0:45:12All bleeding comes from cut vessels.
0:45:12 > 0:45:15All bleeding eventually stops...
0:45:15 > 0:45:17This is Naylor's triad of bleeding.
0:45:17 > 0:45:20All blood comes from vessels. All bleeding comes from cut vessels.
0:45:20 > 0:45:23All bleeding...eventually...
0:45:23 > 0:45:24eventually stops.
0:45:24 > 0:45:27MACHINE BEEPS STEADILY
0:45:27 > 0:45:28She did it.
0:45:31 > 0:45:33Of course she did.
0:45:33 > 0:45:36Tisseel and Surgicel, please. Let's clean this up, shall we?
0:45:44 > 0:45:46SHE PANTS
0:45:49 > 0:45:51Jac?
0:45:51 > 0:45:53Leave me alone.
0:45:53 > 0:45:55Have a drink of water.
0:45:55 > 0:45:57Leave me alone!
0:45:57 > 0:45:59Right, breathe, OK?
0:45:59 > 0:46:03You're stressed. You've been through a lot.
0:46:03 > 0:46:08What would you know about it? You can't understand.
0:46:08 > 0:46:11- SHE SOBS - I know you.
0:46:11 > 0:46:15You are not a surgeon! You don't know what it's like...
0:46:15 > 0:46:18- This isn't about surgery! - It's... Everything's about surgery!
0:46:18 > 0:46:21If I don't have surgery, I don't have anything!
0:46:21 > 0:46:23Look, you've got Emma, OK? You've got Emma.
0:46:23 > 0:46:25- SHE HYPERVENTILATES - No, don't!- All right, listen.
0:46:25 > 0:46:28You think this is about Gaskell? It's not, OK? It's not.
0:46:28 > 0:46:30This is about you and what you've done to yourself.
0:46:30 > 0:46:33It's everything you've put yourself through.
0:46:33 > 0:46:35Jac! Come on. Look...
0:46:35 > 0:46:38This is everything, Jac.
0:46:38 > 0:46:42This is Guy, this is Zosia, this is Fran, this is Emma...
0:46:42 > 0:46:44It's your sister!
0:46:44 > 0:46:46- OK? You need to acknowledge it. - SHE SOBS
0:46:46 > 0:46:49It's Jasmine, OK? You haven't grieved for her.
0:46:49 > 0:46:50Hey, just come on...
0:46:50 > 0:46:54- No, no, no, no...- It's all right.
0:46:54 > 0:46:56- It's OK.- No...
0:46:56 > 0:46:57It's OK.
0:46:57 > 0:46:59SHE SOBS
0:47:08 > 0:47:10- A PFO?- It's made the dementia worse.
0:47:10 > 0:47:12I've booked the first available theatre slot.
0:47:12 > 0:47:16Rox, a hole in the heart we can fix,
0:47:16 > 0:47:19and this is the man we have to thank for spotting it.
0:47:19 > 0:47:21- Oh, no, I wasn't the only one who... - You spotted it.
0:47:21 > 0:47:23You kept your eye on it even after I dismissed you.
0:47:23 > 0:47:25Take the credit, Nurse Chiltern.
0:47:25 > 0:47:27Professor, it's Michael.
0:47:33 > 0:47:36- IN GRUFF AMERICAN ACCENT: - Hey, if I cut loose, I'll revert to
0:47:36 > 0:47:39the animal side of my nature so totally that I may never
0:47:39 > 0:47:41regain my humanity.
0:47:41 > 0:47:45And she's got no idea what we're talking about, does she, Ezra?
0:47:45 > 0:47:47- Wolverine.- Wolverine.
0:47:47 > 0:47:50If he gets wounded, he can heal himself.
0:47:50 > 0:47:52- Is that so?- Mm-hmm.
0:47:52 > 0:47:54I didn't know you were the comic book type.
0:47:54 > 0:47:58Well, there's lots of stuff you don't know about me yet.
0:47:58 > 0:48:01So, Ezra, when your mummy wakes up, we can go and meet your sisters.
0:48:01 > 0:48:03And in the meantime, why don't you show Essie here
0:48:03 > 0:48:05the X-Men game that you were telling me about?
0:48:05 > 0:48:09It worked! Guys...
0:48:09 > 0:48:11Gaskell and Naylor, the spinal implantation,
0:48:11 > 0:48:12it worked.
0:48:17 > 0:48:19He can move his toes.
0:48:19 > 0:48:20I don't believe it.
0:48:20 > 0:48:22It works.
0:48:22 > 0:48:24Well, he's a long way from full recovery yet.
0:48:24 > 0:48:26This is just the beginning.
0:48:26 > 0:48:30if we can get the implant to stimulate axonal regrowth, then...
0:48:30 > 0:48:32Well, it's something at least.
0:48:32 > 0:48:34Oh, it's definitely something.
0:48:38 > 0:48:40There's one more thing I need to show you.
0:48:44 > 0:48:47Do you want my opinion?
0:48:50 > 0:48:52I think you were scared.
0:48:54 > 0:48:58You see so much grief in this place,
0:48:58 > 0:49:02you worry that, if you let it in, there'll be no end.
0:49:02 > 0:49:04Is there?
0:49:05 > 0:49:10Maybe not, but it does get easier.
0:49:11 > 0:49:13I lost control.
0:49:13 > 0:49:17- Jac...- No, no, it's a... It's a good thing.
0:49:17 > 0:49:21I looked him in the eye in there and something happened to me.
0:49:22 > 0:49:26I saw my reflection or something.
0:49:26 > 0:49:30It's hard to explain,
0:49:30 > 0:49:33but it surprised me.
0:49:33 > 0:49:38It was a different me - a better me.
0:49:38 > 0:49:40Now you're starting to worry me.
0:49:42 > 0:49:45I have clarity,
0:49:45 > 0:49:47but he's wrong that it means the end.
0:49:47 > 0:49:50KNOCK AT DOOR
0:49:50 > 0:49:55Hi, I'm sorry to interrupt you, Mr Fletcher.
0:49:55 > 0:49:58Apparently they need you to sign the Trust Marketing Strategy
0:49:58 > 0:50:02or something, and...
0:50:03 > 0:50:05It's OK, what is it?
0:50:05 > 0:50:08David Hopkins, he has a PFO.
0:50:08 > 0:50:10They found him a quiet space on Keller,
0:50:10 > 0:50:12but they need the Darwin Theatre.
0:50:12 > 0:50:14Mr Valentine can do it, and you should observe.
0:50:14 > 0:50:17It'll be good for your CT training.
0:50:17 > 0:50:18Thank you.
0:50:21 > 0:50:22I'll, erm...
0:50:24 > 0:50:26DOOR CLOSES
0:50:34 > 0:50:36DOOR OPENS AND CLOSES
0:51:00 > 0:51:05A cure not just for motor neuron disease, for everything.
0:51:05 > 0:51:08The body's ability to regenerate itself -
0:51:08 > 0:51:10the Holy Grail.
0:51:10 > 0:51:13When I found Lazlo, he'd progressed so rapidly,
0:51:13 > 0:51:15he had weeks to live...
0:51:15 > 0:51:19A year later, he's fully recovered from motor neuron disease -
0:51:19 > 0:51:21fully recovered.
0:51:24 > 0:51:26This is Lazlo.
0:51:29 > 0:51:31Szia.
0:51:31 > 0:51:32Szia.
0:51:32 > 0:51:35..or, if you like, Patient Zero.
0:52:14 > 0:52:15Valentine.
0:52:17 > 0:52:21Before you chastise me for walking out on you in theatre, I didn't.
0:52:21 > 0:52:22I went where I was most needed.
0:52:22 > 0:52:25I know you did, because you always do.
0:52:25 > 0:52:27It's what makes you the doctor you are.
0:52:27 > 0:52:30Jac, I'm not interested in your games.
0:52:31 > 0:52:34I owe you an apology.
0:52:34 > 0:52:38Not because I doubted you - because I never have -
0:52:38 > 0:52:39but because you were right.
0:52:39 > 0:52:40I was afraid.
0:52:42 > 0:52:46You're not going to change my mind. There's nothing you can do.
0:52:46 > 0:52:50You have the ability in abundance, Valentine.
0:52:50 > 0:52:55You have integrity and determination and, above all, you have courage.
0:52:57 > 0:52:58Cuts are killing us.
0:53:00 > 0:53:04Bureaucracy reigns and the truth is no-one's really in charge
0:53:04 > 0:53:07when it matters,
0:53:07 > 0:53:11and yet, amongst it all, you remain constant.
0:53:11 > 0:53:14It's your duty to stay.
0:53:14 > 0:53:17It's your duty to become the consultant you should be.
0:53:20 > 0:53:24The future's here, Valentine, and it needs you.
0:53:28 > 0:53:29Jac...
0:53:35 > 0:53:36Thank you.
0:53:43 > 0:53:45- What...?- She's leaving.
0:53:53 > 0:53:56I keep this on my wall as a reminder.
0:53:56 > 0:54:00Spinal Diffusion Tensor Imaging.
0:54:00 > 0:54:03Oh, I know all the lingo now.
0:54:03 > 0:54:06Lazlo is here for you to study, to examine...
0:54:06 > 0:54:08Treat me as your case study.
0:54:08 > 0:54:12Please, it is my privilege to be here - my utopia.
0:54:19 > 0:54:20Is this...?
0:54:20 > 0:54:22It's Lazlo Furz.
0:54:22 > 0:54:24Patient Zero.
0:54:24 > 0:54:26So they weren't winding me up.
0:54:29 > 0:54:32So that is your dog Rolo outside, barking like he wants to go home?
0:54:32 > 0:54:35And therein lies the crucial fallacy of utopia -
0:54:35 > 0:54:38assuming that everybody has the same vision of what it pertains to.
0:54:38 > 0:54:40- LAUGHTER - Go on. Your dog needs you!
0:54:44 > 0:54:48Save four lives in one go and still humble enough to take the stairs.
0:54:48 > 0:54:51Well, I hear you didn't do too badly yourself.
0:54:51 > 0:54:55I was going to leave this with reception, but...
0:54:55 > 0:54:58What would you say if I told you I was leaving?
0:54:58 > 0:55:01Leaving this place for good - leaving Holby.
0:55:01 > 0:55:03I'd say I don't know what you're talking about.
0:55:03 > 0:55:05Exactly what I just said.
0:55:05 > 0:55:07Or that I don't believe you.
0:55:07 > 0:55:09And then?
0:55:09 > 0:55:11You mean it?
0:55:11 > 0:55:14I've never been more uncertain about anything.
0:55:14 > 0:55:16I don't follow you.
0:55:16 > 0:55:17Just give this to Hanssen.
0:55:17 > 0:55:19I'm going to go say goodbye to Sacha,
0:55:19 > 0:55:21and then I'm going home to my daughter.
0:55:21 > 0:55:23I'll take her as far from all of this as possible.
0:55:23 > 0:55:27So the system's broken and, what, you just abandon it?
0:55:27 > 0:55:30Not broken, just found another future.
0:55:30 > 0:55:32Ah, this is about self-interest.
0:55:32 > 0:55:34You're not understanding me.
0:55:34 > 0:55:36I'm a mother. That's all there is.
0:55:40 > 0:55:42LIGHT SWITCH CLICKS
0:55:52 > 0:55:54DISTANT SIREN WAILS
0:56:02 > 0:56:04What are you...?
0:56:04 > 0:56:06You shouldn't be down here. You can't come in this way.
0:56:10 > 0:56:12LOUD BANG
0:56:15 > 0:56:16What was that?
0:56:23 > 0:56:25SHE GROANS
0:56:26 > 0:56:28PANTING
0:56:37 > 0:56:39SHE GROANS