:00:39. > :00:38.It's likely to be dominated by the controversy over Mr Trump's
:00:39. > :01:40.More senior Republicans have withdrawn their support for his bid
:01:41. > :01:40.of the political elite trying to sabotage his campaign.
:01:41. > :01:40.If you want change in Washington, you vote for Donald Trump.
:01:41. > :01:40.If you want to keep things the same, you vote for Hillary Clinton.
:01:41. > :02:03.Donald Trump has promised to go on the offensive in tonight's
:02:04. > :02:06.I meant what I said and it's still how I feel.
:02:07. > :02:09.In the US Trump has always been a polarising candidate and to many
:02:10. > :02:13.Americans this latest incident hasn't changed their views.
:02:14. > :02:15.Everybody has flaws and things that they do
:02:16. > :02:20.It doesn't mean that he can't be president.
:02:21. > :02:23.I compare it to JFK and Bill Clinton and every politician in the past,
:02:24. > :02:25.especially presidents, they have loved women and women
:02:26. > :02:32.The noise around Donald Trump has drowned out difficult questions
:02:33. > :02:34.for Hillary Clinton about comments she allegedly made in private
:02:35. > :02:39.But she will almost certainly be challenged on that
:02:40. > :02:46.Here, the Government has abandoned proposals to ask businesses
:02:47. > :02:50.to publish details of the number of foreign workers they employ.
:02:51. > :02:52.The idea was unveiled at the Conservative Party
:02:53. > :02:55.Conference, but the plans were criticised by business groups.
:02:56. > :02:57.With me now is our political correspondent, Tom Barton.
:02:58. > :03:02.Tom, what's the background to all of this?
:03:03. > :03:06.Last week's Conservative Party conference the Home Secretary, Kevin
:03:07. > :03:17.Rudd, said The idea was met with howls of
:03:18. > :03:22.protests from business groups who said it could lead to companies with
:03:23. > :03:27.large foreign workforces being named or shamed and even facing boycotts.
:03:28. > :03:28.Today her cabinet colleague told the BBC
:03:29. > :03:34.We will not be asking companies to list, name,
:03:35. > :03:37.publish or identify in any way the number of foreign
:03:38. > :03:45.Ministers may still ask businesses to collect this information so that
:03:46. > :03:50.they can identify industries or parts of the country where there are
:03:51. > :03:54.large numbers of foreign workers. Sources say that the ridge proposals
:03:55. > :03:57.were misinterpreted, but there is no doubt that this is an embarrassing
:03:58. > :04:00.moment for Theresa May's Government. The United Nations says more
:04:01. > :04:03.than 140 people have been killed in an air strike on a funeral
:04:04. > :04:05.ceremony in Yemen. Saudi Arabia described the attack
:04:06. > :04:08.in the capital, Sana'a, as a "regrettable event" and said
:04:09. > :04:12.it would investigate. A Saudi-led coalition of Arab
:04:13. > :04:15.countries has been engaged in air strikes in Yemen
:04:16. > :04:18.for a year-and-a-half. Thousands had come here for
:04:19. > :04:26.a funeral when this hall in Yemen's capital Sana'a was destroyed
:04:27. > :04:32.by an air strike. People were mourning the father
:04:33. > :04:34.of a government minister. TRANSLATION: We came
:04:35. > :04:39.here after the first hit happened. Whilst we are trying to help
:04:40. > :04:42.the survivors and get the people It created a massacre,
:04:43. > :04:49.a very frightening massacre. Hundreds were injured in what the UN
:04:50. > :04:53.has descri ed as a horrific attack. Rescue workers struggled
:04:54. > :04:59.to find survivors. Aid agencies fear the
:05:00. > :05:10.number killed may rise. The Yemeni government
:05:11. > :05:12.condemned the attack. At first the Saude-led coalition
:05:13. > :05:14.denied it was responsible. It later said it would investigate
:05:15. > :05:16.what it called the regrettable and painful bombing in Sana'a,
:05:17. > :05:19.adding it does not target civilians. The conflict in Yemen started
:05:20. > :05:23.in September 2014 when Houthi rebels Saudi Arabia feared influence
:05:24. > :05:27.from Iran and formed a coalition for air strikes with
:05:28. > :05:33.backing from the US. Since then, the United Nations
:05:34. > :05:35.estimates that more than 4,000 This attack is not the first to have
:05:36. > :05:39.killed large numbers The US is involved in the
:05:40. > :05:42.investigation into what happened. It has warned Saudi Arabia
:05:43. > :05:45.that its support for air The Ukip MEP, Steven Woolfe,
:05:46. > :05:52.who suffered two seizures after being involved
:05:53. > :05:55.in an altercation with a colleague, left hospital
:05:56. > :05:59.in Strasbourg this morning. Mr Woolfe, who is a candidate
:06:00. > :06:03.to become the party's next leader, was involved in an incident
:06:04. > :06:06.with fellow MEP Mike Hookem in A new cancer treatment
:06:07. > :06:13.is being described as a potential game changer after promising results
:06:14. > :06:15.in the treatment of Patients who took nivolumab survived
:06:16. > :06:19.longer than those treated And a separate study has found that
:06:20. > :06:24.combining the drug with another immunotherapy medicine shrank four
:06:25. > :06:28.out of ten kidney tumours. Here's our medical
:06:29. > :06:32.correspondent, Fergus Walsh. Last year, Peter Waite
:06:33. > :06:35.from Hertfordshire was told he had terminal kidney cancer,
:06:36. > :06:39.which had spread to his lungs. He went on a trial and instead
:06:40. > :06:45.of chemotherapy received a combination of two immunotherapy
:06:46. > :06:49.drugs, one of them called nivolumab. The drugs shrank his tumours
:06:50. > :06:53.and he suffered few side-effects. He's not cured, but
:06:54. > :06:56.feels very fortunate. Nobody really knows what's
:06:57. > :06:59.in the future, but I can't be any worse off, because I have got
:07:00. > :07:06.something now that's been effective. Immunotherapy drugs work
:07:07. > :07:10.by unmasking cancer cells hiding in the body and priming the immune
:07:11. > :07:15.system to destroy them. Early data from a study of 94
:07:16. > :07:19.patients with advanced kidney cancer showed using immunotherapy drugs
:07:20. > :07:23.in combination significantly reduced the size of tumours in 40%
:07:24. > :07:28.of patients, compared to 5% But although promising,
:07:29. > :07:33.immunotherapy is not There is no one single magic bullet
:07:34. > :07:39.cure that will work for every type of cancer or for every person,
:07:40. > :07:43.so immunotherapy will work for some patients and, unfortunately,
:07:44. > :07:46.will not work for other patients. What we need is more research
:07:47. > :07:50.to help us figure out who are those patients who will best benefit
:07:51. > :07:53.from it and should be given it, but equally, who may not
:07:54. > :07:55.and what is the other alternative In another trial of more than 350
:07:56. > :08:04.patients with advanced head and neck cancer, 56% treated with nivolumab
:08:05. > :08:09.were alive after one year, compared The team at the Institute
:08:10. > :08:15.of Cancer Research at the Royal Marsden Hospital,
:08:16. > :08:18.which led the trial, said it was a potential game changer
:08:19. > :08:27.for this difficult to treat cancer. Lewis Hamilton's hopes
:08:28. > :08:31.of retaining his Formula One After a poor start in Japan
:08:32. > :08:34.this morning, he fought But his team-mate and championship
:08:35. > :08:38.rival, Nico Rosberg, won and with just four races to go
:08:39. > :08:54.is in a strong position Lewis Hamilton could barely hide his
:08:55. > :08:56.disappointment that his title has slipped out of his hands.
:08:57. > :08:58.After victory in Japan, Nico Rosberg only needs to finish
:08:59. > :09:01.second at the four remaining races to take the Briton's crown.
:09:02. > :09:03.Hamilton's hopes slipped away at the start.
:09:04. > :09:05.He's struggled to make good getaways all season,
:09:06. > :09:07.but would never have imagined he would have one as bad
:09:08. > :09:09.as this, as he dropped from second to eighth.
:09:10. > :09:19.He jumped two places during the opening round of pit
:09:20. > :09:22.stops and then in one breathtaking lap passed another three cars.
:09:23. > :09:26.He got the better of Sebastien Vettel after his final pit
:09:27. > :09:30.stop and pushed to the limit to catch Max Verstappen.
:09:31. > :09:32.But second place was beyond him and by the look
:09:33. > :09:38.Rosberg's ninth win of the season secured Mercedes the Constructors'
:09:39. > :09:40.Championship and a 33-point lead over Hamilton is surely
:09:41. > :09:48.The next news on BBC One is at 5.50pm.
:09:49. > :10:13.Hello. A very good afternoon to you. Mixed fortunes over the past few
:10:14. > :10:15.days across the British Isles and I think we are going to continue in a
:10:16. > :10:16.similar vain over the