:00:08. > :00:11.Hello, I'm Ros Atkins, this is Outside Source.
:00:12. > :00:13.Scientists hail a "milestone" in understanding what
:00:14. > :00:23.New research gives a near-complete picture of the genetic mutations
:00:24. > :00:25.involved and could lead to fresh methods of treatment.
:00:26. > :00:29.For years this he has been a mystery, Now he's given
:00:30. > :00:32.an exclusive interview to Rory Cellan Jones and he says
:00:33. > :00:44.I am going to come in front of the camera wants and I will never, ever
:00:45. > :00:49.The BBC's been told that Zika virus could affect far more babies
:00:50. > :00:54.The first cruise from the US to Cuba in nearly 40 years has
:00:55. > :01:10.We are keeping a close eye on the English Premier League. It is
:01:11. > :01:36.Chelsea 0- two Tottenham. To quickly mention that the ball,
:01:37. > :01:41.this is the feed that we have from a pub in Leicester. That is a large
:01:42. > :01:48.group of anxious men, women and children. At the moment, that game
:01:49. > :01:50.is not going to the plan for Leicester. Chelsea are losing 2-0
:01:51. > :02:05.against Tottenham. If Tottenham if Chelsea draw
:02:06. > :02:14.on loose, Leicester have the title. We begin with a story
:02:15. > :02:16.of huge significance. Scientists say they have
:02:17. > :02:21.a near-perfect picture of the genetic mutations that
:02:22. > :02:24.cause breast cancer. Enjoying a spot of Bank Holiday
:02:25. > :02:27.Monday gardening, Vanessa Babbage But Vanessa has fought
:02:28. > :02:30.a long, arduous battle After extensive surgery,
:02:31. > :02:32.chemo and radiotherapy, she knows how devastating the disease
:02:33. > :02:36.and its treatment can be. It's actually worse
:02:37. > :02:42.than the cancer itself, because you are constantly ill,
:02:43. > :02:47.so they do try to help you to minimise the side-effects by giving
:02:48. > :02:50.you other drugs to help the nausea and things like that, so
:02:51. > :02:58.the treatment is very, very harsh. Scanners like this one are used to
:02:59. > :03:01.detect and monitor cancerous tumours once they've already developed,
:03:02. > :03:04.but to understand the underlying causes of cancer, scientists have
:03:05. > :03:09.had to go much deeper, to the level of DNA,
:03:10. > :03:12.to try and work out what happens An international team of scientists,
:03:13. > :03:18.led by the Sanger Institute in Cambridge, examined all 3 billion
:03:19. > :03:22.letters in the genetic code of every What they've found has transformed
:03:23. > :03:29.the understanding of what happens Getting a comprehensive collection
:03:30. > :03:37.of information, including the mutations that are causing cancer,
:03:38. > :03:42.tells us something about why that cancer is going wrong,
:03:43. > :03:44.why that cell is turning into a cancerous cell,
:03:45. > :03:48.and if you can understand that, you can understand the causes
:03:49. > :03:51.of the cancer, and then you can This opens up the possibility
:03:52. > :03:56.of much greater individualised treatments for cancer,
:03:57. > :04:00.targeting each of the mutations. That's already happening with some
:04:01. > :04:02.treatments, like the drug Herceptin, but experts believe this
:04:03. > :04:07.could be a big step forward. What this study might
:04:08. > :04:09.achieve is finding better treatments, matching
:04:10. > :04:11.them better to women. By understanding the causes that
:04:12. > :04:16.underline the biology of different types of the disease,
:04:17. > :04:19.we might be able to match better treatments and offer them things
:04:20. > :04:22.that are more likely to work for Back at home, Vanessa Babbage
:04:23. > :04:27.is moving on with her life after cancer, and she is optimistic that
:04:28. > :04:30.science is starting to make real headway in the fight
:04:31. > :04:33.against the disease. It gives people hope,
:04:34. > :04:37.because when people are affected by someone that they love
:04:38. > :04:41.and they have breast cancer, they hope for a better future
:04:42. > :04:45.for other women that are going to be This research has transformed
:04:46. > :04:49.the understanding of cancer, and offers the tantalising prospect
:04:50. > :04:51.it could prevent the disease This is the Australian
:04:52. > :05:10.businessman who says he created He's called Craig Wright
:05:11. > :05:13.and he's spoken to three media organisations -
:05:14. > :05:23.the Economist and us. Rory Cellan-Jones did
:05:24. > :05:27.the interview for the BBC - First, here's Craig Wright on why
:05:28. > :05:39.he'd rather be doing no interviews. It is my right to say I did
:05:40. > :05:48.something. Why do I have to take credit for its? Why? Wouldn't you be
:05:49. > :05:50.proud? Yes, but that doesn't mean they have to bounce around in front
:05:51. > :06:01.of TV cameras. It's been thought that the founder
:06:02. > :06:09.of Bitcoin will have amassed That would give him or her a net
:06:10. > :06:24.worth of about $450m. Now we know that the Australian Tax
:06:25. > :06:37.Office is taking an interest We have told them about the tax
:06:38. > :06:42.issues and implications. We put in everything but the auditors we were
:06:43. > :06:47.using, and a number of tax lawyers at the time. We had an internal
:06:48. > :06:53.audit and navigate back to the tax office so we could the right amounts
:06:54. > :06:56.of tax. Because the body really understands bitcoins very well, the
:06:57. > :07:03.timing or anything like that, it is still an ongoing matter. Lawyers are
:07:04. > :07:04.negotiating how much tax I will. -- Iowa.
:07:05. > :07:07.Next, here's a message for any journalists or award
:07:08. > :07:23.If anybody ever puts me up for an award, I would never accept the
:07:24. > :07:27.centre. If you put me for a Nobel Prize, put me up for some honour, I
:07:28. > :07:33.will never accept the scent from any of you for anything. I am going to
:07:34. > :07:38.do this once and once only. I am going to come in front of that
:07:39. > :07:46.camera wants and I will never, ever be on a camera ever again for any TV
:07:47. > :07:49.You'd have thought that this announcement might bring an end
:07:50. > :08:05.He has already set off a firestorm on the Internet. There is passionate
:08:06. > :08:12.community around bitcoin, people who know a lot about crypto currencies.
:08:13. > :08:15.They are all arguing if whether he is the real thing. They are saying
:08:16. > :08:21.it is not sufficient proof that he is provided. In the last 20 minutes
:08:22. > :08:26.was so we spoke to the Chief scientist of the bitcoin foundation.
:08:27. > :08:29.He was Sean proof by Doctor Craig Wright and he believes it, so that
:08:30. > :08:35.is quite an endorsement. Can you explain what that says in a way that
:08:36. > :08:39.we can understand? The proof that he has been giving to people is
:08:40. > :08:49.evidence that he has got the big -- digital signature that belonged to
:08:50. > :08:58.the Monaco used to set up the bitcoin transaction, the first one,
:08:59. > :09:02.back in 2009. You know that's nom de plume did that. He is saying he can
:09:03. > :09:06.reproduce that signature and verify that the private code that
:09:07. > :09:12.effectively only that person would have. People will try to pick that
:09:13. > :09:18.apart. Huge controversy raging amongst bitcoin enthusiasts. Some of
:09:19. > :09:22.the leading scientists who have seen the believe it. He is this man and
:09:23. > :09:27.what did he do if he did create bitcoin? He has been around in
:09:28. > :09:35.academic competing circles for quite a while working on this kind of area
:09:36. > :09:40.of crypto currencies. What he did was in 2008, if it is same, at paper
:09:41. > :09:46.was published on the Internet in a very obscure area of the Internet
:09:47. > :09:50.with these matters are discussed. A few weeks later the software to make
:09:51. > :09:56.it happen was released online. He has been public about being involved
:09:57. > :10:00.in bitcoin in one way or another. What is different is that he is
:10:01. > :10:01.claiming he is the man that did it, but he said he did have
:10:02. > :10:04.collaborators. We've talked about the Zika
:10:05. > :10:07.virus a lot recently - but the BBC has learned how it
:10:08. > :10:10.could be far worse than feared. Sarah Robbins said:
:10:11. > :10:19."Scientists studying test-tube "mini-brains" have been astonished
:10:20. > :10:22.to see how fast the Zika virus kills brain cells" A couple of weeks
:10:23. > :10:24.after scientists said more than a quarter of the world's
:10:25. > :10:31.population live in areas at risk. The main risk is that Zika causes
:10:32. > :10:34.case of microcephaly - Estimates are that 1% of women
:10:35. > :10:43.who have had Zika during pregnancy will have a child with microcephaly
:10:44. > :10:51.But now leading doctors in Brazil say that as many as 20%
:10:52. > :10:53.of Zika-affected pregnancies will result in one of a range
:10:54. > :10:56.of other forms of brain damage They've been talking
:10:57. > :11:24.to the BBC's Wyre Davies. Perhaps some of the most interesting
:11:25. > :11:28.work on these mini brains is it shows how effective and destructive
:11:29. > :11:32.the Zika virus can be. Neuroscientists were shocked by what
:11:33. > :11:38.they discovered, a huge reduction in growth of this rebuttal cortex, the
:11:39. > :11:47.crucial outer layer of the brain. We were all astonished by the fast
:11:48. > :11:50.effect. We saw cell death within three days. Within six days, some
:11:51. > :11:57.parts are completely gone. Here's Julia Carneiro in Rio
:11:58. > :12:09.on the steps that are being taken Lots of work is being done on many
:12:10. > :12:14.fronts. Researchers are trying to find out vaccine for Zika. The
:12:15. > :12:18.government, all of the states across the country, are trying to avoid
:12:19. > :12:24.more people getting did, but the virus is spreading in Brazil and in
:12:25. > :12:30.many other countries and it is a very grave situation, especially for
:12:31. > :12:34.pregnant women. The initial assessment, the first studies coming
:12:35. > :12:39.night are trying to find an answer to the question how many women who
:12:40. > :12:43.have Zika during pregnancy Google want to have babies with
:12:44. > :12:49.microcephily? The initial and that suggested might be around 1%. What
:12:50. > :12:55.the scientists are saying is that this number may be higher because it
:12:56. > :12:57.is not just microcephily that may be caused by Zika. There are other
:12:58. > :13:05.neurological problems involved and it might be that one in every five
:13:06. > :13:08.children born to a mother who had Zika during her pregnancy has some
:13:09. > :13:16.kind of problem. That might be a hearing problem, and eyesight
:13:17. > :13:19.problem, convulsions later on in life. These doctors are also saying
:13:20. > :13:24.it is very important to keep following the development of these
:13:25. > :13:29.children, at least in the first two years of their lives to see what
:13:30. > :13:33.will happen because as many people have been saying in the medical The
:13:34. > :13:43.Disappeared that microcephily might be the tip of the iceberg. The
:13:44. > :13:48.English Premier League is at the sharp end of the season and that oil
:13:49. > :13:52.is down to this, Tottenham are away at Chelsea. That is the Leicester
:13:53. > :13:58.City fans watching the game. They know it Tottenham don't win, the
:13:59. > :14:06.team, the most improbable champions in decades. You can tell that it is
:14:07. > :14:10.not going for them. Tottenham are winning 2-0. Stays like that, it
:14:11. > :14:29.will go down to them playing against Everton on Saturday.
:14:30. > :14:39.A man has been shot dead by police in Kent. If followed investigations
:14:40. > :14:48.into a man who was beaten to death in his home in a burglary last
:14:49. > :14:54.month. Armed officers took part in a preplanned operation in relation to
:14:55. > :14:59.them death of the 73-year-old man in Biddenden in March this year. Shots
:15:00. > :15:04.were fired during the incident. One man was fatally injured at the scene
:15:05. > :15:08.and a firearm has been recovered. Formal identification of that man
:15:09. > :15:12.has not yet taken place but the family of a man officers wanted to
:15:13. > :15:18.locate in connection with the murder in Biddenden have been informed. The
:15:19. > :15:21.matter has now been referred to the Independent Police Complaints
:15:22. > :15:33.Commission, as is mandatory for all police shootings.
:15:34. > :15:39.Our lead story is that scientists say they have a near-perfect picture
:15:40. > :15:46.of the genetic events that cause breast cancer.
:15:47. > :15:51.There is a continuation of fighting in Aleppo in Syria. John Kerry is in
:15:52. > :15:56.Geneva trying to salvage a crumbling ceasefire. In the Democratic
:15:57. > :16:03.Republic of Congo, thousands of people have been attending the first
:16:04. > :16:09.day of commercial -- official commemorations for Papa Wemba. As
:16:10. > :16:12.body is lying in the Parliamentary building and will there be taken
:16:13. > :16:19.later to his family home for the public to view. A British firm has
:16:20. > :16:22.admitted the selling a humidifier disinfectant that killed around a
:16:23. > :16:27.hundred people in South Korea. This is the head of the company's South
:16:28. > :16:28.Korean division being attacked by relatives of victims as he
:16:29. > :16:40.apologised. crisis several times -
:16:41. > :16:43.well it's worsened. Its governor says it will NOT make
:16:44. > :16:45.a 400-million dollar repayment There had been negotiations with
:16:46. > :16:55.creditors but a deal wasn't cut. If we look back to the nature of the
:16:56. > :17:01.Puerto Rican economy, it is very uncompetitive. It has a very complex
:17:02. > :17:06.tax system. Its relationship with the United States makes it quite
:17:07. > :17:10.burdensome for companies from outside to settle and understand the
:17:11. > :17:14.system. If we look at the key turning point we can probably go
:17:15. > :17:19.back a decade and look at the exploration of section nine 36 of
:17:20. > :17:23.the internal revenue code, which is to provide special tax breaks for US
:17:24. > :17:29.corporations setting up organisations in Puerto Rico. When
:17:30. > :17:34.those exemptions on corporate income tax were done away with, the economy
:17:35. > :17:38.went into a recession that we are seeing to this day and the local
:17:39. > :17:44.government decided to borrow heavily in order to balance its budget. That
:17:45. > :17:47.effectively is what brings us to the situation today whether government
:17:48. > :17:52.has been spending a lot more than it can afford and now it is in the
:17:53. > :18:00.position where it can't pay its creditors. There has been population
:18:01. > :18:04.movement. Because of Puerto Rico's special relationship of the United
:18:05. > :18:08.States as a territory, if citizens are US citizens and have the right
:18:09. > :18:15.to move freely in the United States. The population has pension shrinking
:18:16. > :18:19.rapidly in the last five years. We can see a situation now with a
:18:20. > :18:22.population of Puerto Rico will actually lose a generation, which
:18:23. > :18:29.would dampen the prospect of economic growth in the medium and
:18:30. > :18:34.long-term as the economic active predator weakens resettle on
:18:35. > :18:42.continental America. If the government does not have money to
:18:43. > :18:47.keep its basic services running, how can it respond to a special crisis
:18:48. > :18:55.and one of the key issues facing Puerto Rico now is the potential
:18:56. > :18:58.expansion of the Zika virus. Michelle, Hanley understand the
:18:59. > :19:04.economic and political relationship between Puerto Rico and America.
:19:05. > :19:09.Part of the problem is that it is a territory not a state. It is not
:19:10. > :19:13.eligible to applied for bankruptcy protection. In the city of Detroit
:19:14. > :19:19.had to file for bankruptcy, it was able to file to get assistance and
:19:20. > :19:24.to apply for certain rules as a state. This is not open to Puerto
:19:25. > :19:36.Rico. That is part of the debate and the application to Congress that at
:19:37. > :19:44.some point Congress should reassessed that. It should be
:19:45. > :19:48.allowed to re-negotiate with its creditors. Since it is not able to
:19:49. > :19:52.do that we are seeing the situation where the government is forced to
:19:53. > :19:56.say we can't make these debt payments. We have seen several
:19:57. > :20:02.repayments being missed. Thinking about the euro in crisis and the way
:20:03. > :20:07.analysts used to talk about contagion if certain debts were not
:20:08. > :20:10.dealt with, is there of the risk that what is happening in Puerto
:20:11. > :20:16.Rico could cross over to the main US economy and have consequences?
:20:17. > :20:20.People like to talk about Puerto Rico being America's Greece, but I
:20:21. > :20:27.think the comparison is more like with the city of Detroit, which had
:20:28. > :20:32.a manager that was brought in to manage the city back to health and
:20:33. > :20:38.take tough economic decisions. The question is, what will Congress do
:20:39. > :20:41.in the case of Puerto Rico? One lawmaker, Paul Ryan, was against the
:20:42. > :20:46.idea of taking control in Puerto Rico, but at the same time taking
:20:47. > :20:50.fiscal control out of the hands of the territory. Something has to be
:20:51. > :20:55.done. A lot of people are pushing for this idea to give them some kind
:20:56. > :20:57.of work around the roof so it can apply for some kind of bankruptcy
:20:58. > :21:03.detection and work at another solution. Whether Congress agrees to
:21:04. > :21:13.that, that is what the talk is at the moment.
:21:14. > :21:25.Next, airships! They are being reinvented by one British company.
:21:26. > :21:31.This hangar has remarkable history. Some of the largest aircraft ever to
:21:32. > :21:36.take to the skies were built here. That was almost a century ago that
:21:37. > :21:42.inside now a new airborne giant is taking place. This is the error land
:21:43. > :21:51.of ten. It is 90 metres long, longer than a super jumbo. It contains
:21:52. > :21:57.28,000 cubic metres of helium and it can stay in the air for five days.
:21:58. > :22:00.It was created by hybrid air vehicles for the US military as a
:22:01. > :22:05.high-flying spy in the sky but the project was cancelled, so the
:22:06. > :22:10.company's engineers brought back all the kit and decided to develop it
:22:11. > :22:17.for themselves. It is a mixture of the plane, helicopter and airships.
:22:18. > :22:22.It is a lifting body shape, it has gas inside it and its engines can
:22:23. > :22:28.trust air up, down, left and right degree of flight. What is it
:22:29. > :22:32.actually like to fly? We are cruising over the centre of London.
:22:33. > :22:39.I have the normal flight instruments. The test pilot is
:22:40. > :22:44.finding out in this simulator. You can feel the inertia of the
:22:45. > :22:48.aeroplane aloft. You make small control in Britain before the clap
:22:49. > :22:51.to respond. It is a bit like steering the ship. Hybrid air
:22:52. > :22:57.vehicles think that it can be used for a huge variety of tasks from
:22:58. > :23:00.disaster relief to tourism. It says the aircraft is almost ready to take
:23:01. > :23:09.to the skies in Britain for the first time.
:23:10. > :23:11.He's no stranger to incendiary comments -
:23:12. > :23:13.today Donald Trump has taken aim at China, saying their raping
:23:14. > :23:16.the US, whilst criticising their trade policy.
:23:17. > :23:25.We have a 500 and dollar deficit, trade deficit, with China. We were
:23:26. > :23:30.going to turn it around. We have the cards. We are like the piggy bank
:23:31. > :23:35.that is being robbed. We have a lot of power with China. If China
:23:36. > :23:39.doesn't want to fix the problem in North Korea we say, fixed the
:23:40. > :23:44.problem because we can't allow China to continue to rape our country and
:23:45. > :23:50.that is what the doing. It is the greatest theft in the history of the
:23:51. > :23:55.world. I have been speaking about this and how it is seen in China. If
:23:56. > :24:00.you look at the figures, China and the US has a huge trade deficit. In
:24:01. > :24:06.the first two months of this year the trade deficits between the two
:24:07. > :24:15.countries reached 57 billion US dollars. This is the kind of
:24:16. > :24:19.interesting, easy rhetoric to sell to the voters, that China is ripping
:24:20. > :24:27.off the US. He has been repeating this line for many months. He used
:24:28. > :24:33.this very derogatory word today. He feels like China is devaluing the
:24:34. > :24:39.currency. The liberally. That is one of the speculations. The reality is
:24:40. > :24:43.more complicated. The reason why Chinese currency is devaluing is
:24:44. > :24:50.partly because Chinese policymakers might want to make China's export
:24:51. > :24:55.more competitive, but also its reflects an economic domestic
:24:56. > :25:01.reality is that a lot of capital is leaving the country. That is to do
:25:02. > :25:06.value that currency. Looking at the economics, the two countries are
:25:07. > :25:11.having a more complicated economic relationship than ever. When Donald
:25:12. > :25:16.Trump speaks, the people in China care? Some do. A lot of the Chinese
:25:17. > :25:23.observers are quite sophisticated and they know this this is China
:25:24. > :25:30.bashing. Ever since President Nixon visited China in 1972, China has
:25:31. > :25:35.been a focal point in every American election. This is not exceptional,
:25:36. > :25:39.at all. It is getting tense and English Premier League. Let's look
:25:40. > :25:44.at the pub in Leicester. If Tottenham don't beat Chelsea,
:25:45. > :25:53.Leicester City will win the championship. Chelsea have a goal
:25:54. > :25:57.back. It is 1-2 at Stamford Bridge. If it stays like that, Leicester
:25:58. > :26:05.will be champions today. We will keep an eye on it.
:26:06. > :26:14.Time to check out some high impact noteworthy weather worldwide. Let's
:26:15. > :26:20.start in North America. We have had an explosion of thick cloud across
:26:21. > :26:21.parts of the deep South. This is the focus for further potentially
:26:22. > :26:22.flooding