:00:12. > :00:18.Good evening and welcome to BBC Our headlines tonight: New hope
:00:18. > :00:23.Good evening and welcome to BBC trial at Frenchay Hospital shows
:00:23. > :00:27.patients from the worst symptoms. So in love — the couple killed by a
:00:27. > :00:28.disqualified driver — now the Prime Minister talks about the offender's
:00:28. > :00:39.The Justice Secretary has asked Minister talks about the offender's
:00:39. > :00:43.Council to review the guidelines for serious driving offences. I think we
:00:43. > :00:47.should look at this specific case in The marksmen who missed who missed
:00:47. > :00:49.their targets — but the government blames the failure on the badgers.
:00:49. > :00:53.And an eye in the sky — US cops blames the failure on the badgers.
:00:53. > :01:06.West Country flying machines to Good evening. There's news tonight
:01:06. > :01:08.pioneered here in the West that could offer new hope to people
:01:08. > :01:11.suffering with Parkinson's disease. Bristol's Frenchay Hospital is
:01:11. > :01:21.piloting a new treatment which can repair damaged brain cells and could
:01:21. > :01:31.reverse the symptoms of the illness. It is early days, but the progress
:01:31. > :01:36.is being watched around the world. Tom is a brave man. He volunteered
:01:36. > :01:41.to be the very first Parkinson's patient in the world to have a long,
:01:41. > :01:49.metal probe and deep into his brain This long needle allows easy protein
:01:49. > :01:58.to be infused which can repair It was trepidation statistically the
:01:58. > :02:05.least —— to say the least. But I thought if you don't try, you don't
:02:05. > :02:11.Scientists here have developed a new way of accessing the brain to inject
:02:11. > :02:17.a chemical which can restart growth. There were signs that this protein
:02:17. > :02:26.could reverse symptoms several years ago. This video shows a man walking
:02:26. > :02:30.before and after receiving the drug. At this trial came to an abrupt
:02:30. > :02:31.before and after receiving the drug. after the company that makes the
:02:31. > :02:35.drug decided to pull out because the results were inconclusive. The
:02:35. > :02:37.Bristol surgeon who pioneered the treatment says that is because the
:02:37. > :02:42.American doctors were not doing treatment says that is because the
:02:42. > :02:50.Our whole focus over the last seven or eight years has been trying to
:02:50. > :02:57.develop a system to reliably deliver drugs to the brain, and that is
:02:57. > :02:59.develop a system to reliably deliver Now a new trial has begun thanked
:02:59. > :03:04.two new equipment tailor made by a This robotic arm has been designed
:03:05. > :03:10.to allow surgeons to put tiny tubes deep into the brain to deliver the
:03:10. > :03:19.growth factor with sub millimetre precision. So far, six patients
:03:19. > :03:22.including Tom and another man from Salford have taken part. The first
:03:23. > :03:31.phase has proved that the treatment I know after nine months I will
:03:31. > :03:39.phase has proved that the treatment the medication, so I am looking
:03:39. > :03:47.the team are looking for another 36 We are hoping to see that this has
:03:47. > :03:49.the promise of the early trial and reverses Parkinson's. We don't know,
:03:49. > :03:56.we are hoping. We are exciting, reverses Parkinson's. We don't know,
:03:56. > :04:03.we are cautious and hoping to do this any rigorous way and answer the
:04:03. > :04:08.This technique is already attracting it works, it could be modified for
:04:08. > :04:12.patients with arrangements. It is still early days, this project could
:04:12. > :04:20.be the breakthrough in the treatment of Parkinson's adopters everywhere
:04:20. > :04:24.In a moment, we'll give you details of how you can volunteer. But first
:04:24. > :04:35.joining us now from London is Doctor Kieran Breen who is the Director of
:04:35. > :04:38.This sounds very encouraging, but how different is this from other
:04:38. > :04:43.treatments that are available at the At the moment all the treatments
:04:43. > :04:47.that are available to read the symptoms of the condition, but they
:04:47. > :04:51.don't actually stop the progression of the death of nerve cells. This is
:04:51. > :04:58.the first treatment whereby we can inject something, to try and reverse
:04:58. > :05:02.the progression of the cell deaths. The cells will regrow, they will be
:05:02. > :05:08.former connections, and the brain will start working in the normal
:05:08. > :05:14.That is tremendously encouraging. How harmful are the symptoms to
:05:14. > :05:16.That is tremendously encouraging. No two people have exactly the same
:05:16. > :05:22.symptoms, but people usually present with stiffness, slowness, some have
:05:22. > :05:27.a tremor. Over time this progresses. Some have problems with sleep or
:05:27. > :05:29.depression or memory problems, but also one of the key problems that
:05:30. > :05:34.people with Parkinson's disease also one of the key problems that
:05:34. > :05:38.falling. The potential of breaking bones and breaking hips. These are
:05:38. > :05:48.all problems affect people with reverse it, we will, essentially,
:05:48. > :05:52.You need more people to take part in the trial, but what sort of patients
:05:52. > :05:58.are you looking for to take part in There are very specific set of
:05:58. > :06:03.criteria for people to take part. It basically depends on the symptoms
:06:03. > :06:08.condition and the medication they are wrong and how well they respond
:06:08. > :06:14.to the medication. All these details are available on the Parkinsons
:06:14. > :06:21.to the medication. All these details You will give us a warning, I'm
:06:21. > :06:24.Of course, as you had an interview, we have had six people who took
:06:24. > :06:26.Of course, as you had an interview, ensured that the procedure is safe,
:06:26. > :06:28.and now we need to go ahead with the drug. We will be following the
:06:28. > :06:32.people for up to 18 months, and drug. We will be following the
:06:32. > :06:41.then will we be able to find out Let's hope. Thank you for joining
:06:41. > :06:44.If you want to volunteer for the next stage of the trial then there
:06:44. > :06:54.are more details and information on the Parkinsons UK website. The
:06:54. > :06:57.address is on your screen now. A former police community support
:06:57. > :07:00.officer from Gloucestershire who's on trial for smuggling drugs into
:07:00. > :07:03.Indonesia has appeared again in court. Andrea Waldeck, who worked in
:07:03. > :07:05.Cheltenham, is alleged to have smuggled thousands of pounds worth
:07:06. > :07:20.of crystal meth through Surabaya Airport. If convicted, she could
:07:20. > :07:23.The Prime Minister has suggested that the sentence given to the
:07:24. > :07:27.Bristol man who killed a young couple out cycling in Hanham should
:07:27. > :07:32.be reviewed. Ross and Clare Simons died when Nicholas Lovell crashed
:07:32. > :07:40.into their tandem bike. He'd already been disqualified from driving.
:07:41. > :07:44.Ross and Clare Simons had only been married for 18 months and had just
:07:44. > :07:47.finished a course of IVF treatment when Nicholas Lovel smashed into
:07:47. > :07:50.them in Hanham. Serial offender Lovell was yet again driving without
:07:50. > :08:03.a licence and had previously been The couple's MP had told the House
:08:03. > :08:12.of Commons that people don't think Over a thousand people petitioned
:08:12. > :08:16.for the law to be changed so that people already disqualified it
:08:16. > :08:19.should receive tougher sentences. Will the Prime Minister receive
:08:19. > :08:21.should receive tougher sentences. petition, and does he agree the
:08:21. > :08:23.should receive tougher sentences. Today David Cameron paid tribute to
:08:23. > :08:28.Ross and Clare and told MPs he thinks the ten and a half year
:08:28. > :08:36.sentence should be looked at again. This is the most appalling crime. As
:08:36. > :08:41.he says, someone with ten previous convictions, disqualified at the
:08:41. > :08:43.justice secretary has asked the council to review the sentencing
:08:43. > :08:46.guidelines for serious driving offences, and I think we should
:08:46. > :08:48.guidelines for serious driving at this case in the light of that.
:08:49. > :08:54.Ross's father, mother and sister have been campaigning for a change
:08:54. > :08:58.sentences for repeat offenders. He was laughing about the fact that
:08:58. > :09:03.he will be out in a couple of years. It's time that the law took into
:09:03. > :09:10.account people think of what they It completely destroyed us, to be
:09:11. > :09:15.honest. Our family and clear's family... It will never be the same,
:09:15. > :09:19.The Attorney general's office told the BBC that normally cases can
:09:19. > :09:21.The Attorney general's office told be referred to the Court of Appeal
:09:21. > :09:24.within 28 days of the sentence being passed. Ross and Clare's families
:09:24. > :09:37.say they'll continue their fight for justice — whatever the outcome of
:09:37. > :09:44.the Prime Minsiter's words today. You're watching Points West. It
:09:44. > :09:50.the Prime Minsiter's words today. 6:40pm. Stay with us, as there is
:09:50. > :09:55.In the water for 100 days, we catch up with the swimmer trying to make
:09:55. > :09:59.And celebrities come to Cheltenham —— find out what these famous faces
:09:59. > :10:00.had to say when they came to the Cheltenham Literature Festival
:10:00. > :10:07.The West's controversial badger Cheltenham Literature Festival
:10:07. > :10:10.could now continue into November. Today the government confirmed that
:10:10. > :10:16.extensions of two to three weeks were being sought for both Somerset
:10:16. > :10:20.Marksmen have failed to shoot enough badgers. It's part of efforts to
:10:20. > :10:26.tackle bovine tuberculosis which they can spread to cattle. The
:10:26. > :10:35.six—week cull in West Somerset ended was due to end next Monday. Our
:10:35. > :10:39.Somerset Correspondent, Clinton Rogers has been gauging reaction to
:10:39. > :10:54.todays' news and joins us from the Thanks. We are at the centre of
:10:54. > :10:56.todays' news and joins us from the Somerset has been in the national
:10:56. > :11:03.media spotlight on and off for the factions have argued and squared up
:11:03. > :11:09.whether killing badgers is the way to tackle TB in cattle. What a lot
:11:09. > :11:13.of people had thought was that aspect cull came to the end, the
:11:14. > :11:16.guns would fall silent and maybe the arguments would quieten. How wrong
:11:17. > :11:21.we were. It seems that the cull arguments would quieten. How wrong
:11:21. > :11:24.set to continue, and the arguments At Camp Badger in Somerset, today's
:11:24. > :11:31.news was greeted with a mixture At Camp Badger in Somerset, today's
:11:31. > :11:41.government of cynically manipulating the figures to disguise a gross
:11:41. > :11:44.It's obviously been a failure, and the government really ought to stand
:11:44. > :11:49.up and say it has been a failure. It has not worked. Instead, they are
:11:49. > :11:56.changing the goalposts so that they committed look like it has worked.
:11:56. > :12:08.goalposts. It is a wild animal, subject to the vagaries of weather,
:12:08. > :12:11.hear now only 850 have been killed. Why? Well, it seems the original
:12:11. > :12:22.estimate of the badger population was too high. So that's been revised
:12:22. > :12:27.downwards from 2,400 to 1,450. Now achievable, and the National Farmers
:12:27. > :12:38.Union locally says for the whole future of farming, Defra's cull
:12:38. > :12:43.Union locally says for the whole They have overturned 20 years of
:12:43. > :12:47.political thrust crass mission and inactivity which is led us to this
:12:47. > :12:51.situation with cattle slaughtered and the disease out of control and
:12:51. > :12:57.the danger of Europe making us into an isolation zone and shutting down
:12:57. > :13:00.farms, which is what a lot of the anti—cull campaigners actually want.
:13:00. > :13:03.But one farmer in Gloucestershire whose herd has been affected by
:13:03. > :13:10.But one farmer in Gloucestershire says he's not surprised the shooting
:13:10. > :13:11.because we failed to actually kill the requisite number in the time
:13:11. > :13:19.period that we were supposed to the requisite number in the time
:13:19. > :13:23.that it is down purely to somebody in Natural England getting the
:13:23. > :13:30.Whether this nightime cull is now in disarray clearly depends on which
:13:30. > :13:34.Whatever the argument, it's likely now that an extension of up to three
:13:34. > :13:41.weeks will now be granted for the nightime shooting in both Somerset
:13:41. > :13:44.What is clear is that for as long as the shooting goes on, here and in
:13:44. > :13:46.Gloucestershire the protesters will stay and do what they can to disrupt
:13:46. > :14:03.Political Editor Paul Barltrop. stay and do what they can to disrupt
:14:03. > :14:08.proposed extension is creating much challenge for the police — what
:14:08. > :14:11.proposed extension is creating much It's been really big for them, they
:14:11. > :14:13.have had to devote a lot of time and manpower to it. That in scores of
:14:13. > :14:16.officers going out like to keep manpower to it. That in scores of
:14:16. > :14:22.peace between the marksmen and the protesters. Before it started, there
:14:22. > :14:28.was an estimate it would cost the forces each year £1 million. That is
:14:29. > :16:34.natural England reckon it could We could see cull going on for
:16:34. > :16:38.You will keep us posted, would you? A man who took up residence in a
:16:39. > :16:41.tree to protect it from a housing development has been charged by
:16:41. > :16:41.tree to protect it from a housing police. Rowan Burrough was arrested
:16:42. > :16:45.at the site in Stroud yesterday police. Rowan Burrough was arrested
:16:45. > :16:50.has now been charged with common He'll appear in court in Cheltenham
:16:50. > :16:58.next month. The tree has now been An independent review into fraud and
:16:58. > :17:03.corruption in the water park society says no further action needs to
:17:03. > :17:06.corruption in the water park society taken. Dennis Grant was jailed in
:17:06. > :17:11.2011 after admitting fraud totalling more than £660,000. The city of
:17:11. > :17:16.London police carried the case compelling evidence to support
:17:16. > :17:23.claims that other public officials Police in Florida have taken to
:17:23. > :17:25.claims that other public officials skies to catch criminals — with
:17:25. > :17:27.claims that other public officials help of an engineering firm based in
:17:27. > :17:30.rural Dorset. The officers strap an aero—engine to their backs and fly
:17:30. > :17:43.paragliders at high speed. Scott The West Country's renowned for
:17:43. > :17:47.aviation. And Semley — on the Dorset Wiltshire border — is now part of
:17:47. > :18:01.that aero industry. Here, in a converted barn, they make motors
:18:01. > :18:06.Fire up now, and I we. If you want to fly, there is no option. This is
:18:06. > :18:11.the best way, the cheapest way and the most thrilling form of flying
:18:11. > :18:20.selling worldwide. In Florida, Palm Bay Police use the Dorset built
:18:20. > :18:21.selling worldwide. In Florida, Palm A lot of the work we are using is
:18:21. > :18:29.for search and rescue, as well as someone is growing crops in the
:18:29. > :18:34.middle of a field, rather than rearrested scan a large area, the
:18:34. > :18:36.using paramotors which takes one person 20 minutes to fly across
:18:36. > :18:37.using paramotors which takes one field and find what they're looking
:18:37. > :18:43.helicopter costs £1,200 an hour field and find what they're looking
:18:43. > :18:51.fly, a paramotor, ten. And its more The issue with unmanned vehicles is
:18:51. > :18:56.that the information is then passed back to a control centre, and that
:18:56. > :18:59.has to be processed. If you have a physical person in the sky, they can
:18:59. > :19:02.make decisions based on what they can see in the environment around
:19:02. > :19:05.The company's hoping to develop markets in the Middle East. And
:19:05. > :19:10.South Africa — where paramotors poachers. The man behind the company
:19:10. > :19:16.helped Bear Grylls fly a paramotor over Everest in 2007. He wants to
:19:16. > :19:24.grow the leisure market also — by making paramotors as popular as
:19:24. > :19:24.grow the leisure market also — by If someone had been told 100 years
:19:24. > :19:28.ago that in the future you have If someone had been told 100 years
:19:29. > :19:31.machine in the back of a car like this that you can carry around any
:19:31. > :19:34.case they wouldn't believe you. this that you can carry around any
:19:34. > :19:35.we're trying to show the world that this is what we have and it is
:19:35. > :19:50.And the next project — a flying this is what we have and it is
:19:50. > :20:00.Destined for the skies over Semley. What fun. I want to go. Where would
:20:00. > :20:03.The Wiltshire snooker player Stephen Lee has appealed against his 12—year
:20:03. > :20:06.ban for match—fixing The former world number five is appealing
:20:06. > :20:09.against the sanction, findings and costs, following an independent
:20:09. > :20:11.tribunal hearing in Bristol last month. Lee was found to have fixed
:20:11. > :20:17.seven matches, including a game month. Lee was found to have fixed
:20:17. > :20:19.He's been in the water for over month. Lee was found to have fixed
:20:19. > :20:21.hundred days — attempting to be month. Lee was found to have fixed
:20:21. > :20:24.first person to swim the length month. Lee was found to have fixed
:20:24. > :20:27.mainland Britain — from Lands End to John O'Groats. Sean Conway — whose
:20:27. > :20:30.dry land base is Cheltenham — is hoping to raise thousands of pounds
:20:30. > :20:35.for charity. Jules Hyam's been keeping an eye on his progress.
:20:35. > :20:40.He began his endurance swim 102 keeping an eye on his progress.
:20:40. > :20:43.ago — it probably feels like longer. Since June 30th, Sean Conway's been
:20:43. > :20:50.swimming about the same as a channel 32—year—old claims he's not a very
:20:50. > :20:54.good swimmer — chances are he's 32—year—old claims he's not a very
:20:54. > :20:57.a little better by now. It's a pretty straightforward swim really —
:20:57. > :21:00.he's only had to deal with salt water swelling his tongue, his
:21:00. > :21:08.support crew getting sea sick, those not quite as scary as swimming
:21:08. > :21:23.through what the crew say is a Hopefully I will finish in the next
:21:23. > :21:29.two or three weeks. The Scottish water is getting very cold at the
:21:29. > :21:34.moment. Every week I take longer, that will make me even slower, so I
:21:34. > :21:41.just need to man up little bit and Sean had planned to spend three
:21:41. > :21:45.months on the journey — he and his crew are now well into month four —
:21:45. > :21:48.and a new challenge is looming — funding the final stretch so he
:21:48. > :21:49.and a new challenge is looming — complete his mission. Today Sean's
:21:49. > :21:52.swimming past Loch Torridan opposite South Rona — further north than
:21:52. > :21:56.Inverness. Big waves have been hampering his progress, but he is
:21:56. > :22:06.getting closer to his 1,000 mile And you can read Sean's diary and
:22:06. > :22:20.follow exactly where he's got to on Gloucester full—back Olly Morgan has
:22:20. > :22:21.Olly, capped twice by England, has not played since damaging his knee
:22:21. > :22:26.ligaments in January last year. not played since damaging his knee
:22:26. > :22:32.contract with the Cherry and Whites in 2004 and made a hundred and
:22:32. > :22:33.contract with the Cherry and Whites Swindon Town are through to the
:22:33. > :22:35.contract with the Cherry and Whites quarterfinals of the Johnstone's
:22:35. > :22:40.Paint Trophy after beating Plymouth Argyle last night. Goals from Jack
:22:40. > :22:42.Bartram and Nicky Ajose sealed a 2—1 victory for Swindon, who came back
:22:42. > :22:49.from being a goal down. Bristol victory for Swindon, who came back
:22:49. > :22:52.are out, having lost at Wycombe Wanderers. 2—0 down at half—time,
:22:52. > :23:01.this great strike from Brendan Moloney wasn't enough to keep them
:23:01. > :23:04.Now, if you are a lover of books Cheltenham is the place to be this
:23:04. > :23:17.week. Its annual Literature Festival speakers there's usually something
:23:17. > :23:21.to interest everyone. And today there was a host of famous faces on
:23:21. > :23:27.offer — as Ali Vowles has been The appropriately named club band
:23:27. > :23:32.from Bath, whose music is based The appropriately named club band
:23:32. > :23:37.love of books. There was certainly no shortage of eager readers lapping
:23:37. > :23:39.up access to the authors. It felt a little bit like spot the celebrity
:23:39. > :23:47.writer. Each was keen to sign a little bit like spot the celebrity
:23:47. > :23:54.books, making someone's day. The theme is memories. I would have
:23:54. > :24:02.memories of my childhood autograph book, and today I was certainly
:24:02. > :24:10.Did I pull the plug out of the Film critic Barry Norman has watched
:24:10. > :24:15.over 15,000 films in his lifetime, the first one scene the Saturday
:24:15. > :24:19.I remember vividly the first ones were Westerns — the good guys were
:24:19. > :24:25.with white hats and the guys —— were Westerns — the good guys were
:24:25. > :24:32.bad guys had black cats. If they had black cats. If the official here,
:24:32. > :24:37.Ruby wax, here is the mental health Ambassador, says she has no memory
:24:37. > :24:41.of when her depression first hit. You have no memory. It's like ——
:24:41. > :24:47.it's like nature blesses you. I You have no memory. It's like ——
:24:47. > :24:51.it offensive when someone says, doesn't make you more creative?
:24:51. > :25:00.it offensive when someone says, say, do you say that to someone
:25:00. > :25:00.it offensive when someone says, And I was talking about his passion
:25:00. > :25:13.I can remember wanting to draw, And I was talking about his passion
:25:13. > :25:17.when I did want to draw, I thought, I want to draw it, I am still me.
:25:17. > :25:39.Cheltenham. Such a talented man Now the weather: we will have plenty
:25:39. > :25:46.more sunshine tomorrow then we had A lot of cloud full stop you can see
:25:46. > :25:53.that the cloud is moving swiftly, propelled away by a north—westerly
:25:53. > :26:08.temperatures. Today with the wind fresher. For the rest of today,
:26:08. > :26:14.straight northerly tomorrow. That continues into the weekend. It is
:26:14. > :26:21.inviting, autumnal if not winter Tomorrow, despite the cold, plenty
:26:21. > :26:29.of sunshine. Crisp and clear with showers will be pushed Southeast
:26:29. > :26:33.Road. Winds will ease down during the second half of the night. Rural
:26:33. > :26:40.temperatures will be pretty cold. Cold enough any few years for a
:26:40. > :26:45.touch of grass frost. And very nice morning, it is not until the second
:26:45. > :26:48.half of the day that cloud begins to bubble up. With the wind speed,
:26:48. > :26:51.watch out for the temperatures. bubble up. With the wind speed,
:26:51. > :27:02.direction of the wind means it will feel bitterly cold. Wind chill will
:27:02. > :27:03.make the temperatures feel the work. A big jump from where we began the
:27:03. > :27:10.week. We retain the clear skies A big jump from where we began the
:27:10. > :27:13.Friday, but the cloud will come A big jump from where we began the
:27:13. > :27:17.from the eastern area, bringing A big jump from where we began the
:27:17. > :27:22.little bit of rain. Friday, some damp and cloudy conditions, still
:27:22. > :27:26.with wind speeds in the north—east. It will be called no matter what.
:27:26. > :27:31.The area of low pressure will bring damp area into Friday and Saturday.
:27:31. > :27:45.Saturday grey and gloomy, and the That's it for now. You will practice
:27:45. > :27:45.your broadcasting later, would you? Yes, badly. I'll see you at 10pm,