:00:00. > 3:59:59Nick Clegg tells his supporters to stand firm, dismissing talk
:00:00. > :00:00.of Hello and welcome to
:00:00. > :00:00.Wednesday's Look East. Coming up
:00:00. > :00:00.in the next thirty minutes: A major breakthrough for MS
:00:07. > :00:08.sufferers, as a wonder drug developed in this region is approved
:00:09. > :00:13.for use on the NHS. It isn?t a cure,
:00:14. > :00:16.I can?t say it is a cure. But I have not had MS
:00:17. > :00:20.for eleven years. A date is set for Cambridge Lib Dems
:00:21. > :00:26.to discuss Nick Clegg's futtre. And it is all aboard the
:00:27. > :00:30.Poppy Express for a picnic with a difference
:00:31. > :00:42.in aid of the Royal British Legion. I will be here later in the
:00:43. > :00:48.programme live from the Suffolk Show, with the BBC is marking 1 0
:00:49. > :00:54.years since World War I. Thdre are many re`creations and stands and
:00:55. > :01:00.even a school in that ten. Over there is a record office whdre
:01:01. > :01:03.people can trace the involvdment of the relatives during World War I.
:01:04. > :01:09.Join me later. The new drug,
:01:10. > :01:14.developed in this region, which scientists say is a breakthrough
:01:15. > :01:18.for people with multiple sclerosis. It is called Lemtrada and is
:01:19. > :01:22.the result of decades of research It has now been approved by the
:01:23. > :01:29.health body NICE and in thrde months Multiple sclerosis is a condition
:01:30. > :01:36.of the central nervous systdm. It affects more than 100,000
:01:37. > :01:40.people across the UK. Symptoms start in your 20s or 3 s
:01:41. > :01:44.and it affects almost three times In a moment, we will hear rdaction
:01:45. > :01:51.from the MS Society, but first His hands and arms went numb
:01:52. > :02:06.and he lost sight in one eyd. But for more than a decade now,
:02:07. > :02:10.he has suffered no symptoms after It does not affect
:02:11. > :02:13.my day`to`day life. It does not affect my work,
:02:14. > :02:16.my social life. I only have to think about ht when I
:02:17. > :02:21.get holiday insurance. Other than that,
:02:22. > :02:23.I am absolutely fine. I'm healthier now than I was
:02:24. > :02:26.in the past. Last year, I completed thred
:02:27. > :02:32.half`marathons in one month. This is the drug `
:02:33. > :02:35.now called Lemtrada. A fluid injected directly
:02:36. > :02:38.into the blood stream. Developed in Cambridge over
:02:39. > :02:41.the last forty years, Prof @laistair The drug is the most effecthve
:02:42. > :02:50.treatment for multiple sclerosis It reduces the accumulation
:02:51. > :02:57.of disability and allows a good proportion
:02:58. > :03:00.of patients to improve over time. MS is caused by rogue immund cells `
:03:01. > :03:05.these red splodges here, attacking the nerve ending and damaging its
:03:06. > :03:10.coating around the blue are` here. The drug replaces bad cells with
:03:11. > :03:14.good cells and then the nerve We treated the first patient
:03:15. > :03:20.in 1991. At that stage, we were treating
:03:21. > :03:24.people with rather advanced disease. We learned over
:03:25. > :03:26.a number years that was probably not There was a switch
:03:27. > :03:31.in the late 1990s to treating people The drug is now approved
:03:32. > :03:38.by the health body NICE. Anthony was
:03:39. > :03:40.among 2,000 people worldwidd who It could help around half those
:03:41. > :03:47.newly diagnosed with the condition. If it continues for another 11
:03:48. > :03:56.years I will be happy with that The development of this drug is very
:03:57. > :04:00.much a Cambridge story, avahlable on Mike Cartwright, BBC Look E`st,
:04:01. > :04:07.Cambridge. Earlier I spoke to
:04:08. > :04:10.Dr Susan Kohlhaas, the head of biomedical research at the
:04:11. > :04:12.MS Society, who explained exactly Some people with MS experience
:04:13. > :04:21.relapses and then they get Others with MS experience
:04:22. > :04:28.progression, This drug is helpful for people
:04:29. > :04:34.with relapsing, remitting MS. So out of the number
:04:35. > :04:39.of people living with MS at the moment, how many of them ard in that
:04:40. > :04:43.group that this drug could benefit? We do not have exact figures
:04:44. > :04:47.on that. There are around 100,000
:04:48. > :04:52.people with MS in the UK. 85 per cent of people, when they are
:04:53. > :04:59.diagnosed, are diagnosed with the So most people
:05:00. > :05:04.at some stage within their journey with MS will be diagnosed whth
:05:05. > :05:07.relapsing, remitting MS. What are those associated
:05:08. > :05:13.with this drug? About one third
:05:14. > :05:16.of people who take this drug develop They can be caught early
:05:17. > :05:23.and treated but it is something that people have to be aware of
:05:24. > :05:26.and it should be monitored Do you think that the potential
:05:27. > :05:33.benefits outweigh that risk? That is a very personal dechsion
:05:34. > :05:38.that needs to be made by people with MS who choosd to take
:05:39. > :05:42.the drug in conjunction with advice We know there is a problem hn the UK
:05:43. > :05:49.with access to medicines and a lot of people with relapsing, rdmitting
:05:50. > :05:53.MS who are eligible for the current Even though it will be available on
:05:54. > :06:01.the NHS, and NICE have rubbdrstamped it, you are saying there is
:06:02. > :06:04.a risk that people who could benefit from this drug still will not be
:06:05. > :06:08.able to get access to it. There is a risk that people who do
:06:09. > :06:13.not have the correct inform`tion or access to a healthcare
:06:14. > :06:16.professional will be unable to We are saying that people should
:06:17. > :06:21.arrange an appointment with a healthcare professional to
:06:22. > :06:26.discuss their treatment opthons You are looking forward to seeing
:06:27. > :06:30.this drug available on the NHS? This is great news
:06:31. > :06:35.for people with MS and we hope that it is made available to everyone who
:06:36. > :06:38.would benefit. Dr Susan Kohlhaas
:06:39. > :06:42.talking to me earlier. The body
:06:43. > :06:44.of a man has been discovered The remains were found
:06:45. > :06:51.by a dog walker in the earlx hours of this morning near Tyesdale,
:06:52. > :06:54.in the Bretton area of the city The police are treating
:06:55. > :06:57.the man's death as unexplained. They are awaiting the results of a
:06:58. > :07:00.post mortem examination, whhch has More than 1,600 ex`servicemdn
:07:01. > :07:13.and women in this region received some form of help from the
:07:14. > :07:16.Royal British Legion last ydar. The charity exists to support
:07:17. > :07:18.service personnel returning And today, two young veterans took
:07:19. > :07:22.a special train journey to promote Fundraising for the
:07:23. > :07:37.Royal British Legion ` not just here for older vetdrans,
:07:38. > :07:41.but also for people like Sal Jack who was blinded in Afghanistan
:07:42. > :07:55.after facing a ricocheting bullet. Once I was shocked, I came round and
:07:56. > :07:59.help was there. To have that help there was incredible. They came to
:08:00. > :08:07.my house to make sure that everything was OK and it was safe
:08:08. > :08:12.meat walk around. The charity will stage a national picnic day in June
:08:13. > :08:17.to keep pace with the ?2 million that I needed every week and help
:08:18. > :08:24.those leaving the armed forces. It is very important to us. We need
:08:25. > :08:32.people to understand that wd are fundraising 365 days of the year.
:08:33. > :08:41.Something like the poppy picnics is a way for us to show the public we
:08:42. > :08:48.are doing things. I think it is important that people are aware of
:08:49. > :08:52.people whose fight for our country and need support when they get back.
:08:53. > :08:59.It is a good way of sharing awareness. Another Afghanistan
:09:00. > :09:07.veteran was homeless after leaving the Army. He is now helping the
:09:08. > :09:16.Legion. It is making people aware of the poppy appeal. The British Legion
:09:17. > :09:21.have been fantastic with me. Without them I would not be here now. It is
:09:22. > :09:27.hoped that this latest appe`l will raise at least ?1 million to help
:09:28. > :09:34.the latest veterans returning from conflict around the world.
:09:35. > :09:37.The Liberal Democrats in Calbridge have decided to hold a vote
:09:38. > :09:42.on whether to support the party leader, Nick Clegg.
:09:43. > :09:46.A meeting has been set for two weeks' time, in which party members
:09:47. > :09:50.will decide if Mr Clegg is the best person to lead the Lib Dems in
:09:51. > :09:55.It follows the party's dism`l performance at the recent local
:09:56. > :09:59.Our reporter, Ben Bland, is at the Guildhall in Cambridge for ts now.
:10:00. > :10:08.Some of the questions startdd when the Liberal Democrats lost control
:10:09. > :10:15.of this counsel for the first time in many years. In two weeks time,
:10:16. > :10:20.the party's supporters in C`mbridge will meet to decide whether Nick
:10:21. > :10:26.Clegg should continue as le`der on whether they want an election to
:10:27. > :10:37.choose a new leader. Local lembers what an opportunity to disctss it.
:10:38. > :10:40.Activists on the streets have had questions and we feel as an
:10:41. > :10:50.executive that we should get our members at large the opporttnity to
:10:51. > :10:57.take part in a discussion. Tnder the party rules, is 75 groups c`ll for
:10:58. > :11:00.an election it would happen. But some people do not want to wait and
:11:01. > :11:09.have signed a letter calling on Nick Clegg to stand down. Nick Clegg can
:11:10. > :11:14.be a very good advocate of causes but unfortunately he is so tnpopular
:11:15. > :11:21.now that he can damage causds. That is why I signed the letter. I do not
:11:22. > :11:26.think you can be a party le`der when so many people are unwilling to give
:11:27. > :11:33.you a fair hearing. The MP for Cambridge as a Liberal Democrat but
:11:34. > :11:36.the other parties will be fhghting for the seat in the general
:11:37. > :11:41.election. The question for the Liberal Democrat is whether Nick
:11:42. > :11:46.Clegg is the right person to lead them?
:11:47. > :11:49.The parents of a teenage girl killed in a car crash
:11:50. > :11:52.in Northamptonshire have fahled in their bid to have a speed limit
:11:53. > :11:57.Rebecca Taylor lost control of her car six years ago
:11:58. > :12:01.Her parents have been fighthng to have the speed limit cut
:12:02. > :12:05.The Taylor home is filled with memories of Rebecca.
:12:06. > :12:08.This self`portrait is one of the last paintings she dhd
:12:09. > :12:12.The 18`year`old was killed six years ago on this stretch of road
:12:13. > :12:17.Since her death, her parents have been campaigning to have thd speed
:12:18. > :12:28.One of the suggestions that we have the
:12:29. > :12:30.One of the suggestions that we have that
:12:31. > :12:34.may have possibly make a difference for Rebecca would have been a
:12:35. > :12:39.Rebecca needed a split second, that is all, and it would h`ve been
:12:40. > :12:44.She may have ended up in thd ditch and missed the other car colpletely.
:12:45. > :12:47.It would have made some difference, it clearly would have done.
:12:48. > :12:51.An inquest into Rebecca's ddath heard that on the day of thd crash
:12:52. > :12:54.Standing water may have been a contributing factor.
:12:55. > :12:57.Northamptonshire County Council does not consider this to be
:12:58. > :13:00.a dangerous stretch of road and it has rejected calls to reduce
:13:01. > :13:06.In a statement, it said a strvey showed the majority of vehicles
:13:07. > :13:10.travelled "significantly below 0 miles an hour" and most below 5 mph.
:13:11. > :13:13.In the past three years, thdre had been only "one recorded collision
:13:14. > :13:18.involving serious injury", which it said was a relatively low ntmber.
:13:19. > :13:20.It added that there was "no compelling evidence to support
:13:21. > :13:27.Nationally, more than 1,000 people died on rural roads in 2010 ` twice
:13:28. > :13:33.Safety campaigners say drivdrs often think rural roads are safer
:13:34. > :13:39.Yet, speeds travelled are much hhgher.
:13:40. > :13:43.Chris Taylor says his familx are still coming to terms with Rebecca's
:13:44. > :13:47.death, but he says they will continue to campaign in her name.
:13:48. > :14:14.Now, over to Stewart at the Suffolk Show for the rest of the programme.
:14:15. > :14:19.Welcome back to the Ipswich Showground at the BBC events marking
:14:20. > :14:25.100 years since the outbreak of the First World War. This has bden one
:14:26. > :14:31.of the most popular events here You get the chance to be a World War I
:14:32. > :14:35.reporter. They have two loc`l presenters there, and you c`n go in
:14:36. > :14:38.and pretend to be a reporter. We will find out what we have been
:14:39. > :14:47.doing here at the events. A new recruit for kitchen's army.
:14:48. > :15:24.This one is perhaps a 90% bored stiff, 10% frozen stiff,
:15:25. > :15:29.10% scared stiff and it was in colour.
:15:30. > :15:35.The tour includes a seven hour show of music, theatre, poetry and
:15:36. > :15:39.debate. Today, it was the great wall question Time.
:15:40. > :16:48.Tell us about world war talk.
:16:49. > :16:56.We will introduce you to a historian from the area, who was at the
:16:57. > :17:00.trenches. Just outside the town What effect would it have h`d on the
:17:01. > :17:07.town? It would have had a massive effect
:17:08. > :17:11.on East Anglia. A lot of people left the farms. The farming becale
:17:12. > :17:17.crucial to keep the country fed Even here, partway through the war,
:17:18. > :17:23.the division come to Ipswich to train. They are put in housds around
:17:24. > :17:28.the town. Even now, 300 yards away, there are trenches in the fhelds for
:17:29. > :17:38.training. They are in the golf course. It had a big impact. 30 000
:17:39. > :17:42.men arrive, and author wrotd about his time here. It was a massive
:17:43. > :17:48.amount of people in the town. How important were we in thd region
:17:49. > :17:55.to what was happening in thd war? We were crucial. There is the coast,
:17:56. > :18:01.there are factories here. Vhew `` the East Anglia Munitions committee
:18:02. > :18:06.were very important, huge alounts of work going on. Feeding the country,
:18:07. > :18:10.using farming. And all of the people who went to fight.
:18:11. > :18:27.I know a lot of people will have seen the film all the play Wall ``
:18:28. > :18:38.but the British Army used the courses better than the Gerlans
:18:39. > :18:42.Yes, the Germans used many of their horses straightaway, and thdn their
:18:43. > :18:49.farming had to be done by h`nd. The British Government use the farmers,
:18:50. > :18:55.the British farmers were looking after the horses that were `lready
:18:56. > :19:01.owned by the army. There were many horses left on farms so that farming
:19:02. > :19:08.could carry on. Such big, heavy horses to move
:19:09. > :19:16.really heavy guns, the Suffolk horses played a very import`nt role.
:19:17. > :19:26.We will find out more about that set of courses now. `` horses.
:19:27. > :19:37.It has been bred here for generations.
:19:38. > :19:43.In 1914, it was providing horsepower in its purist form.
:19:44. > :19:49.A tractor would have been a rarity. They were coming through and farmers
:19:50. > :19:54.who had them a lot. But the horses ruled the fields.
:19:55. > :20:01.With their plodding power, they were untouchable. The war effort was
:20:02. > :20:06.critical, a decision was looming. Food production was very reliant on
:20:07. > :20:13.men and the power of horses. But these were also needed for the wall.
:20:14. > :20:17.There was a big debate about how many horses and men should be taken
:20:18. > :20:23.to be used on the Western front or should they be used to help the food
:20:24. > :20:28.situation. That period has been well documented
:20:29. > :20:32.as part of a drive during food production, this land was alongst
:20:33. > :20:37.swathes of countryside that return to farming. The country had little
:20:38. > :20:42.choice. Germany was trying to blockade Britain, which relhed
:20:43. > :20:46.heavily on imports. It proved a turning point, not least
:20:47. > :20:54.because it gave fresh impetts to the development of new machinerx.
:20:55. > :20:57.The necessity was the mother of invention. That happen in the Second
:20:58. > :21:01.World War, as well. When you look back on the changes
:21:02. > :21:05.that we have seen, where will we be on 100 years time? I have no idea.
:21:06. > :21:08.When you look at the machinds of today, it makes you wonder what they
:21:09. > :21:14.can do next. As for the punch, it has gone from
:21:15. > :21:17.being essential to endangerdd. But it is still hanging on, strong,
:21:18. > :21:32.sleek and a survivor. We have been learning about life
:21:33. > :21:37.here for ordinary people. How did it change from 1914 to 1918?
:21:38. > :21:42.There was a big change. People thought it would be a short war but
:21:43. > :21:47.they became aware. One of the problems for agriculture was, when
:21:48. > :21:53.the war broke out, we imported 0% of all our food. 80% of our wheat
:21:54. > :21:59.and 40% of our beef. The Germans started to cut the supply is off
:22:00. > :22:02.with their boats by 1915, and with conscription in that same ydar, the
:22:03. > :22:08.men were going off and the women had men were going off and the women had
:22:09. > :22:11.to do all the work. It had to be all hands on deck.
:22:12. > :22:16.So the lives of women changdd massively? Yes, that is right. They
:22:17. > :22:21.had to leave being in service and either work in agriculture or
:22:22. > :22:30.factories. After the war, service ended, if
:22:31. > :22:36.people had gone into it? They did not want to go back to it
:22:37. > :22:40.after the war. They did not want to go back to being servants. @fter the
:22:41. > :22:46.war, the men had to have thdir jobs and the priority was given to them.
:22:47. > :22:49.The women were encouraged to go to the home and have families.
:22:50. > :22:55.So women had a life that ch`nged so much on them they were expected to
:22:56. > :22:59.forget it? Yes. That women could not forget it totally, because they were
:23:00. > :23:04.given the vote. Not everybody, if you were under the age of 30, you
:23:05. > :23:10.did not get it on 1929. But there was that step forward. And, of
:23:11. > :23:17.course, socially. Britain w`s a more equal country after the Second World
:23:18. > :23:24.War. Before the First World War the population, 90% of the wealth was
:23:25. > :23:29.aimed `` earned by 4% of thd population. That changed gr`dually.
:23:30. > :23:33.The men went off and they fought in some horrible conditions. They were
:23:34. > :23:38.expected to come back and gdt on with their lives. And imagine that
:23:39. > :23:43.nothing had happened. How dhd they do that?
:23:44. > :23:49.I think a lot of men were lost, psychologically. For four ydars of
:23:50. > :23:56.their life, they had had th`t new existence and they had a calaraderie
:23:57. > :23:59.of an all`male environments. It was very extreme circumstances.
:24:00. > :24:03.Suddenly, they have lost all of that they had to come back to thdir
:24:04. > :24:07.families and to a country that they felt to did not understand them
:24:08. > :24:12.And East Anglia would have looked very different to them?
:24:13. > :24:17.Yes, that is right. And lifd would have continued what they were way?
:24:18. > :24:22.Yes, but with being geared tp for the war effort. Factories change
:24:23. > :24:28.what they were producing, more people were working in agriculture.
:24:29. > :24:32.The government had a bigger role. We have been looking at the sky The
:24:33. > :24:34.temperatures had fallen slightly and there is a cloud above us. Here is
:24:35. > :24:46.the weather. Tomorrow, there could be sole
:24:47. > :24:51.showers around. There has bden low pressure today, a a lot of cloud.
:24:52. > :24:56.Some of that cloud has prodtced rain and drizzle. Misty conditions
:24:57. > :25:00.throughout the region. A further risk of light rain and drizzle
:25:01. > :25:06.overnight. For many of us, we should end the night with dry condhtions.
:25:07. > :25:11.The temperatures will not f`ll very low, because there will be cloud
:25:12. > :25:16.around protecting us. Down to 1 Celsius at the lowest, and ` light
:25:17. > :25:19.easterly breeze. Tomorrow, we start off with a a lot of cloud around,
:25:20. > :25:24.but it will improve with thd brightness and was in sunshhne
:25:25. > :25:28.breaking through the cloud. That will bring with it the risk of some
:25:29. > :25:32.sons `` showers. It could bd heavy and slow moving. If you catch a
:25:33. > :25:38.shower, it could be a heavy downpour. In between those showers,
:25:39. > :25:42.that is the prospect of somd sunshine, especially across the
:25:43. > :25:46.southern counties. And wherd we get sunshine, the temperatures will
:25:47. > :25:52.maybe climb to around 16 or 17 degrees. There will be a moderate
:25:53. > :25:55.easterly winds, and that will have the effect of making our
:25:56. > :26:00.temperatures are little cooler, especially on the coast, highs of 14
:26:01. > :26:05.or 15 degrees. Be aware of the showers, you may get away whth it,
:26:06. > :26:10.but if you catch one, you whll know about it, because they could be
:26:11. > :26:10.heavy and long, possibly with some thunder.
:26:11. > :26:13.Those showers will clear through the Those showers will clear through the
:26:14. > :26:18.evening and overnight, so bx the time you get to Friday, it hs
:26:19. > :26:22.looking more dry. This is a promising pressure chart for the
:26:23. > :26:27.weekend, high pressure from the south`west. This weather front is
:26:28. > :26:31.moving from the West, that could bring some wet weather, but it is
:26:32. > :26:36.not expected to arrive until the end of the weekend. So when improving
:26:37. > :26:43.forecast. If you get to the end of the showers at the weekend, there
:26:44. > :26:47.will be some sunshine, with temperatures around 17 degrdes. The
:26:48. > :26:51.weekend is looking dry, you cannot rule out an isolated shower, but
:26:52. > :26:55.there will be sunshine to come on Saturday. As the weather front
:26:56. > :27:00.approaches by Sunday, it cotld turn our clouds `` skies cloudy. And we
:27:01. > :27:13.will go back to Stuart. Before we go, let me tell you about
:27:14. > :27:18.this stand. It has been one of the most popular. It is done with the
:27:19. > :27:24.Imperial War Museum. People can come in here and they get access to of
:27:25. > :27:29.the Imperial War Museum. Thdy can log on with details of their
:27:30. > :27:33.relatives and they can get, if they are lucky, the military records of
:27:34. > :27:38.somebody and find out more `bout them, things that they did not know.
:27:39. > :27:44.It has been a fascinating d`y. From all of us, good night.