:00:00. > :00:00.First tonight, leading the fight against dementia.
:00:00. > :00:07.The University of Cambridge has been chosen as one of five hubs around
:00:08. > :00:10.Britain seeking new ways to diagnose, treat and
:00:11. > :00:20.We are really going to be able to use that everything that Cambridge
:00:21. > :00:30.has. Thousands more homes planned for
:00:31. > :00:34.Corby. What happened to the marathon man
:00:35. > :00:38.that ran in London with a tumble dryer on his back?
:00:39. > :00:41.Later, I am in Newmarket, the home of horse racing, talking to a
:00:42. > :00:47.sporting great, Lester Piggott. First tonight, leading
:00:48. > :00:52.the fight against dementia. The University of Cambridge has been
:00:53. > :00:55.chosen as one of five hubs around Britain seeking new ways
:00:56. > :00:58.to diagnose, treat and Together, they'll form
:00:59. > :01:03.a Dementia Research Institute, thanks to ?250 million
:01:04. > :01:06.of public money. The research here will centre
:01:07. > :01:12.on the Cambridge Biomedical Campus We'll hear why campaigners say it's
:01:13. > :01:18.big step forward in a moment. First, this report
:01:19. > :01:35.from Mike Cartwright. Ian became his mother's carer. Jean,
:01:36. > :01:42.who died aged 35 -- 85. Diagnosed in dementia -- 2009 with dementia. My
:01:43. > :01:46.mum didn't even recognise me. And, then, at the time, you thought,
:01:47. > :01:53.crikey, things are bad. She hadn't got a clue who I was. It will only
:01:54. > :02:00.be on the increase, with people living longer. It is only going to
:02:01. > :02:10.get worse over the next ten or 15 years. Now at Cambridge Biomedical
:02:11. > :02:16.Campus, new labs, more money. The site chosen among five in the
:02:17. > :02:19.country to drive dementia is. My lab works on understanding the basic
:02:20. > :02:26.mechanism of dementia and making new treatments. We bring and by
:02:27. > :02:29.physicists, using state-of-the-art techniques, we really will be able
:02:30. > :02:36.to use everything that Cambridge has and it is a spectrum of excellence,
:02:37. > :02:40.to focus on dementia. And we will recruit scientists from around the
:02:41. > :02:43.world and we are looking for accelerated excellence and leading
:02:44. > :02:50.scientist, join us. On the right, healthy brain, on the left, one that
:02:51. > :02:56.is shrunken in size because of dementia. Things here working on
:02:57. > :03:03.treatments, the new centre looking more into the causes one day they
:03:04. > :03:07.hope to find a cure. The overall Institute's mission is to understand
:03:08. > :03:12.causes, particularly early stages when you are most likely to be able
:03:13. > :03:15.to help people. We are getting 13 million initially but there is more
:03:16. > :03:21.investment project it, to bring in great new scientist, the world 's
:03:22. > :03:24.leading and best to tackle dementia. Ian has seen the devastating effects
:03:25. > :03:29.of to mention. No family should go through what his went through, he
:03:30. > :03:32.told us. Any advance in research is welcomed.
:03:33. > :03:34.So, what will the new hubs mean for patients?
:03:35. > :03:36.The Chief Scientific Officer of the charity Alzheimer's Research
:03:37. > :03:44.Dr David Reynolds told me why it's an exciting time.
:03:45. > :03:50.It is a very exciting time in dementia is. The area for many years
:03:51. > :03:55.had been underfunded, compared to a lot of other major diseases. We are
:03:56. > :04:00.seeing the beat in trace in the amount of research funding and
:04:01. > :04:03.therefore, the understanding of these diseases that helps us bring
:04:04. > :04:08.medicines to patients. What do you hope will be achieved with these new
:04:09. > :04:14.hubs? We're talking about better prevention, but feel? Most of the
:04:15. > :04:22.research will be about understanding the basic mechanisms at the cellular
:04:23. > :04:27.level. What causes brain cells to have these diseases. From that, you
:04:28. > :04:33.can lead to treating the disease with medicine. Can you give us any
:04:34. > :04:38.idea of how far away a cure or effective medication or prevention
:04:39. > :04:42.might be? There are things being worked on in clinical trials at the
:04:43. > :04:45.moment that we hope will come through in the next years to
:04:46. > :04:49.patients as medicines they can get through their doctors. An effective
:04:50. > :04:53.treatment early enough can look like a cure if you never get the symptoms
:04:54. > :04:56.but we are some way of getting to that point for the patience of
:04:57. > :05:02.today. How important is the establishment of these hubs and
:05:03. > :05:04.Cambridge being one of them? It is really important, it starts to move
:05:05. > :05:08.the Pledge of the previous government and the David Cameron as
:05:09. > :05:14.the global action plan for dementia into reality, and therefore we can
:05:15. > :05:19.start to do that research, get that understanding bring those medicines
:05:20. > :05:22.to patients. We do have a general election coming up, what sort of
:05:23. > :05:26.messages are you hoping to hear from the main part is about funding in
:05:27. > :05:29.the future? We're really hoping to hear that the main parties and
:05:30. > :05:35.ultimately whoever wins is committed to by mental -- biomedical research
:05:36. > :05:40.for dementia. This country has a fantastic science base that helps us
:05:41. > :05:43.understand diseases and bring medicines to patients and it is
:05:44. > :05:47.important that we don't lose that through a general election. It feels
:05:48. > :05:51.like a subject we are talking about more these days. That must be good.
:05:52. > :05:57.It is, as people understand now where are of the impact of the
:05:58. > :06:03.dementia on people, then it helps people understand it, it helps get
:06:04. > :06:05.people engaged with a might participate in research, for
:06:06. > :06:07.example, and it helps also to bring in funding to actually solve the
:06:08. > :06:09.problems. Next tonight, the plans
:06:10. > :06:12.for 4,500 new homes in Corby. If approved, the development
:06:13. > :06:14.to the west of the town would bring almost 3,000 jobs,
:06:15. > :06:16.as well as schools The plans have been submitted
:06:17. > :06:20.but already concerns have been raised about the scale
:06:21. > :06:22.of the project. Stuart Ratcliffe is at
:06:23. > :06:38.the proposed site now. The town of Corby is just behind me
:06:39. > :06:44.at the other side of the road. Under these plans, it will mean that the
:06:45. > :06:48.town of Corby crosses over the road and we will move over into those
:06:49. > :06:53.fields behind me. The developers say it is vital that these plans to go
:06:54. > :06:59.ahead. Corby is considered to be a real boom town. It is predicted the
:07:00. > :07:03.population of Corby will double by the year 2031.
:07:04. > :07:11.You can see why do voters say these plans are a sustainable urban
:07:12. > :07:15.extension. While it stretches the boundaries of Corby, some question
:07:16. > :07:20.the sustainability tag, and in Rushton, there are concerns about
:07:21. > :07:24.infrastructure. Traffic has increased at a clearer last few
:07:25. > :07:29.years and this, it. I think the infrastructure needs looking at
:07:30. > :07:33.first before the houses are built. Doctors surgeries, schools, etc, the
:07:34. > :07:37.impact it might have on Kettering General Hospital. All those things
:07:38. > :07:42.give us concern. The developer and is planned for this parcel of land
:07:43. > :07:48.and is being put forward by the estate who say that Corby West will
:07:49. > :07:51.seamlessly blend with its rural settings. But, again, the sheer size
:07:52. > :07:57.of that of element is concerning some residents. If we're not
:07:58. > :08:01.careful, a lot of the local towns and villages will join up. Kettering
:08:02. > :08:06.is expanding in this direction with the warehouse to lament over there.
:08:07. > :08:14.Corby is expanding in this direction. So, you know, where does
:08:15. > :08:20.it all end? This land has been officially earmarked for their own,
:08:21. > :08:25.last ten years and with the planning application lunch with the planning
:08:26. > :08:29.Council, it looks like Corby could rapidly change. The
:08:30. > :08:36.element -- the developers told me they have consulted widely. The
:08:37. > :08:39.plans with that borough council and they will carry out their own public
:08:40. > :08:42.consultation and those plans could well be amended before going to full
:08:43. > :08:50.planning committee led this year. This really is a long-term project
:08:51. > :08:53.Corby, huge to element, 4500 homes and disorder they do get the
:08:54. > :08:56.go-ahead, this develop and won't be complete until 2021.
:08:57. > :08:58.Next tonight, he's promised to create a modular homes
:08:59. > :09:00.factory in the Fens, building up to 20 homes
:09:01. > :09:02.a day, if he becomes mayor of Cambridgeshire.
:09:03. > :09:05.Businessman Peter Dawe is one of seven candidates aiming to become
:09:06. > :09:07.the county's first devolved mayor with increased powers over housing,
:09:08. > :09:12.In the latest in our series profiling the candidates,
:09:13. > :09:25.Mousumi Bakshi puts Peter Dawe in the mayoral hot-seat.
:09:26. > :09:38.Peter, good to meet you. Take a seat. Why should people vote for
:09:39. > :09:45.Peter Dawe? What's that your part but Mark I'm a visionary, I can see
:09:46. > :09:49.a very big pig Joa, I can see that there are solutions to a lot of the
:09:50. > :09:57.problems in Cambridge in housing and transport. They actually don't need
:09:58. > :10:01.more money than is available. Do you have a guide dear? The one big fish
:10:02. > :10:08.and you would bring in if elected? I believe we can go to micro cars,
:10:09. > :10:16.electric cars, in our urban environment. How much money has been
:10:17. > :10:24.put aside for housing? Round about 70 billion, I think. Tell us one
:10:25. > :10:33.thing people might not know about you. I was -- I was brought up in a
:10:34. > :10:41.council house, Sullivan newsagent. Why would you make a good man? I am
:10:42. > :10:45.coming in with several visions that will help transform local government
:10:46. > :10:50.in Cambridgeshire. I believe that councils have completely lost the
:10:51. > :10:57.plot. And that what we have got to do is bring 21st-century solutions
:10:58. > :11:02.into it. And I can't see how the party political system has got the
:11:03. > :11:09.ability to do transformational change. Where is your favourite
:11:10. > :11:15.place to go in Cambridgeshire? My home. I live just outside Ely. I
:11:16. > :11:18.have the most fabulous view of Ely Cathedral and a sunset when it is
:11:19. > :11:22.honeyed in the morning is wonderful. Northampton Saints have
:11:23. > :11:24.named their new chief executive. He was head of operations
:11:25. > :11:28.at the Olympic Park for London 2012. He takes over from Allan Robson,
:11:29. > :11:31.who is retiring after 20 Well, while most eyes
:11:32. > :11:35.were on the London marathon this weekend, in Northampton
:11:36. > :11:37.they were celebrating a slightly more modest but no less
:11:38. > :11:39.impressive achievement. 83-year-old Bob Emmerson completed
:11:40. > :11:42.a five kilometre park run. But what makes this particularly
:11:43. > :11:45.notable is that it was his 250th run Each Saturday morning,
:11:46. > :11:57.hundreds of people in Northampton You can see more celebrations on the
:11:58. > :12:19.Facebook page. That's all from me. Welcome to Newmarket, this is the
:12:20. > :12:24.National heritage centre for horse racing and sporting art. There's a
:12:25. > :12:28.big separation going on in that room behind me, lots of champagne.
:12:29. > :12:32.Especially a couple of the trophies because at the end of next weekend,
:12:33. > :12:37.this is the trophy for this 1,000 Guineas which is on the 7th of May,
:12:38. > :12:41.and this is the trophy for the 2000 Guineas, which is on the 6th of May.
:12:42. > :12:48.Last year it was won by Frankie Dettori, trained by Hugo Palmer and
:12:49. > :12:51.today Tom Williams has been to meet him.
:12:52. > :12:53.For Hugo Palmer, a horse well with its weight in gold.
:12:54. > :12:57.Galileo Gold, a Guineas winner, on a glorious day
:12:58. > :13:03.The fact that we were able to get such a dream run with
:13:04. > :13:07.Galileo Gold last year, I still, I pinch myself
:13:08. > :13:20.Frankie Dettori won the Guineas and a first for Hugo Palmer.
:13:21. > :13:21.What is a victory like that mean for you?
:13:22. > :13:24.Well, what it's meant is that we've got more clients and more
:13:25. > :13:28.horses this year, which is very exciting and while it's not entirely
:13:29. > :13:32.a numbers game, racing, having 40 or 50 more
:13:33. > :13:37.that within those 40 or 50, there's going to be another champion.
:13:38. > :13:40.Galileo Gold struck gold for trainer Hugo
:13:41. > :13:47.Even if he doesn't win another race, at least he's won the
:13:48. > :13:50.Guineas but he'll be hoping for many more.
:13:51. > :13:55.You've got Escobar this year, I'm sure you'd love
:13:56. > :14:00.I would love to protect and defend the crown but I would hate to
:14:01. > :14:05.We worked Escobar at Newmarket last week and
:14:06. > :14:09.he didn't quite sparkle in the way that we wanted him to and the way
:14:10. > :14:12.that Galileo Gold had 12 months earlier.
:14:13. > :14:14.This year, all eyes are on Frankel's babies.
:14:15. > :14:20.His offspring three years old and part of the classic
:14:21. > :14:23.His son won the Guineas trial at Newmarket.
:14:24. > :14:25.Being the first British classics of the
:14:26. > :14:30.that everyone wants to win and the
:14:31. > :14:32.added excitement this year is the fact that
:14:33. > :14:38.girls and boys, will be competing in the 1,000 and 2000 Guineas.
:14:39. > :14:41.Back in the yard, Hugo has another 12 days
:14:42. > :14:44.to think about defending the 2000 Guineas.
:14:45. > :14:49.1000 Guineas and of course the memories of last year will last
:14:50. > :15:13.These are the foods of horses that have done very well. When the horse
:15:14. > :15:18.died, they cut the fifth of entering them inkwell. Upstairs there is a
:15:19. > :15:19.great exhibition about one of our greatest ever sporting heroes,
:15:20. > :15:24.Lester Piggott. For nearly 50 years,
:15:25. > :15:25.Lester Piggott rode The first one in 1948, aged just 12,
:15:26. > :15:40.on a horse called The Chase No wonder he looms large
:15:41. > :15:46.here at the National Heritage He's one of those names that
:15:47. > :15:50.transcends racing into the general He's got such a presence and such
:15:51. > :15:54.an historic presence. For someone who's had such
:15:55. > :15:57.an extraordinary career, well over 1957 was a very special
:15:58. > :16:07.for Leester and Newmarket, 21-year-old Lecster won his first
:16:08. > :16:11.ever 2000 Guineas race on the horse, Crepello, and this
:16:12. > :16:14.is one of the hooves from Crepello and later
:16:15. > :16:17.on that year, they went on to win
:16:18. > :16:18.the Derby together. It's Crepello and Lester Piggott
:16:19. > :16:22.is drawing ahead yard by yard And for Lester Piggott,
:16:23. > :16:28.it's two winners Thousands will get to see that
:16:29. > :16:32.famous old hood=f and the tiny trophies thanks to Lester's
:16:33. > :16:36.generosity and they might even catch a glimpse of the
:16:37. > :16:39.greatest ever jockey. It's wonderful when he
:16:40. > :16:41.comes into the museum. He sometimes comes very quietly
:16:42. > :16:46.to see things but it's lovely for the public also
:16:47. > :16:48.to know that great names of racing are coming
:16:49. > :16:50.in to the 60 years on from that famous
:16:51. > :16:56.season in 1957, Newmarket is preparing for another
:16:57. > :17:00.Guineas Festival next week, a fitting time to remember
:17:01. > :17:16.a sporting icon. Some fabulous stuff in here. This is
:17:17. > :17:21.one of the very old original soaks that the jockeys used to wear. A
:17:22. > :17:25.great pleasure for me today, I sat down with Lester Piggott. He's man
:17:26. > :17:29.who sometimes doesn't see a great deal but he was in very good mood
:17:30. > :17:35.this afternoon and I started by asking him about his very first
:17:36. > :17:37.Guineas winner. There were quite a few riders that day and he was the
:17:38. > :17:59.big favourite. He came with two furlongs to go and
:18:00. > :18:03.he won quite comfortably. But he was a very good horse. I've been
:18:04. > :18:10.listening to you talking about a lot of your very big races and you
:18:11. > :18:19.remember them so well. Do you have a mental picture of each race, each
:18:20. > :18:28.big race? Not really! I've won some little races as well. You remember
:18:29. > :18:33.the good ones, I think. Living around here, some pictures of you in
:18:34. > :18:43.your prime. What do you think of that jockey now? Well, he wasn't too
:18:44. > :18:49.bad! What was it, do you think, that set you apart from all the other
:18:50. > :19:00.jockeys. Was a determination? For you that much a better writer? No,
:19:01. > :19:06.not really, but I got a lot of good horses and I learned to ride. Very
:19:07. > :19:16.modest. You did very well on horses that shouldn't have one, didn't you?
:19:17. > :19:22.Well, it was a great story on it is a great story. I loved the right.
:19:23. > :19:33.That was a big thing. Were you more focused or what was it that did it?
:19:34. > :19:39.Not really. I was working at it. It was hard work? And the highs for
:19:40. > :19:46.you, what with the big highs in your career? Obviously the Derby because
:19:47. > :19:55.they meant so much more in those days than they do now. The Derby is
:19:56. > :20:03.everybody's favourite. Everybody wants to win the Derby. If you could
:20:04. > :20:10.pick one moment in your life, see a Derby winner, what would that moment
:20:11. > :20:23.the? Well, I think it would have to be the first one. Never say die?
:20:24. > :20:31.That was a great moment. Never say die wasn't fancied to win, was it?
:20:32. > :20:40.Not really but I think it was 33-1. But he was quite good, especially on
:20:41. > :20:43.a left-handed course. Nobody knew that at that time. You knew it but
:20:44. > :20:49.no body else did, is that what you're saying? It made no difference
:20:50. > :20:53.to him. He was exceptional. Do you remember that moment when you cross
:20:54. > :21:03.the line for the first time on Derby? I remember halfwit up the
:21:04. > :21:13.straight, yes. He went crazy. You aware at the time how big a
:21:14. > :21:18.celebrity you where when, you are up there with Muhammad Ali and George
:21:19. > :21:23.Best? Probably. But you don't think about those things. Did you not?
:21:24. > :21:29.Now. Would you have had it any other way? But really, no. Lester Piggott,
:21:30. > :21:35.thank you very much for talking to us.
:21:36. > :21:37.The region has a new world record holder.
:21:38. > :21:41.Ben Blowes from Suffolk broke the record for running
:21:42. > :21:43.the fastest marathon carrying a household appliance.
:21:44. > :21:46.He completed the London Marathon with a tumble dryer on his back
:21:47. > :21:59.The new world record is five hours, 30 minutes. How was it? A long day.
:22:00. > :22:06.Were you the only person carrying something. Yes. I kept hearing
:22:07. > :22:10.people say, there's a bloke with the washing machine. What did you do
:22:11. > :22:19.with it when you finish? I put it in a skip. I needed to get it off my
:22:20. > :22:24.back. I said my goodbyes. Was it getting a bit hard towards the end?
:22:25. > :22:30.Six hours is a long time to be carrying it? It was, it was a tough
:22:31. > :22:34.all day. The last two hours were grim. The worst bit is when you're
:22:35. > :22:41.getting to the end or do you have a spell in the middle where you think?
:22:42. > :22:45.From 13 to 20 miles was a pretty dark time. Something clicked at 20
:22:46. > :22:48.miles and then I picked up the pace and just manage to get under the
:22:49. > :22:55.six-hour limit. Were you overtaken by anything in fuzzy dress? I was
:22:56. > :22:56.overtaken by a rhinoceros! I thought I'm not getting beaten by Irene
:22:57. > :23:10.Austria. Congratulations. The weather is next.
:23:11. > :23:15.It may be late April but winter is not done just yet. At last year in
:23:16. > :23:19.late April, we got a spell of cold weather on the well. Not today.
:23:20. > :23:26.These are today's highs. 13 and 14 from any. We have had this cold
:23:27. > :23:30.front sinking southwards. But much rain and behind that, north-westerly
:23:31. > :23:33.winds ticking over and that will introduce which Calder, Arctic air
:23:34. > :23:37.tonight and tomorrow. The average for this time of year is 13 15 is
:23:38. > :23:41.above average for today but over the next few days, were below average
:23:42. > :23:47.and more importantly, some damaging overnight frost for some of us. As
:23:48. > :23:51.we head towards the end of the week, temperatures recovered by the
:23:52. > :23:56.weekend, were up to the mid-teens and above average. Similar scenes
:23:57. > :23:59.across the region today. A lot of cloud for many of us. Some rain here
:24:00. > :24:05.and there but it didn't amount to much. A lot of cloud on the
:24:06. > :24:08.satellite picture. Northerly winds in behind that bringing there are
:24:09. > :24:13.conditions tonight but also colder conditions as well. 'S evening, some
:24:14. > :24:17.rain in the South. Then we try tonight with some good clear spells
:24:18. > :24:22.developing and a breeze blowing from the north-west carrying spells of
:24:23. > :24:25.rain in the North. These could have sleet mixed in the butt in the clear
:24:26. > :24:31.spells, temperatures getting the below freezing. Here is the jet
:24:32. > :24:37.stream pattern for tomorrow and into Wednesday. A lot of cold air within
:24:38. > :24:43.that and that is a classic set up for April showers so already showers
:24:44. > :24:46.from the world go in Norfolk. Many do, try and sunny, if rather chilly
:24:47. > :24:52.start with. Sunshine in the morning but cloud will develop and we will
:24:53. > :24:56.get showers developing more widely. The far south could stay dry in the
:24:57. > :25:01.day. The showers could have some hail, thunder and sleet mixed in the
:25:02. > :25:06.sunshine, 11 degrees, but feeling chilly in that brisk north-westerly
:25:07. > :25:11.wind. As we go into Wednesday, another chilly start. There will be
:25:12. > :25:15.some heavy ones, some hail again but equally interspersed with some
:25:16. > :25:21.sunshine and highs of nine or 10 degrees. I pressure at West but the
:25:22. > :25:25.flow coming back in both the Atlantic as we get into thirsty. A
:25:26. > :25:29.cold, frosty start on Thursday but some early sunshine. More cloud
:25:30. > :25:36.sinking down from the North as we go through the day. Not amounting to
:25:37. > :25:39.two much but a bit wet here and there. Friday, a good deal of dry
:25:40. > :25:43.weather initially but there will be a few showers. But everywhere
:25:44. > :25:47.catching these but they will be heavy and could be slow-moving as
:25:48. > :25:52.well. Temperatures nudging up to 12 or 13. That is the trend into the
:25:53. > :25:56.bank holiday weekend. With Minnie driver Saturday. Sam Hain
:25:57. > :26:02.potentially on Sunday. Uncertainty as to how quickly that will clear.
:26:03. > :26:06.Rain not too far away on Monday but some of us could get away with a dry
:26:07. > :26:15.day and it will be mild throughout the weekend. That's it from me. Just
:26:16. > :26:21.before we go, have a look at this statue. It's a horse cold around
:26:22. > :26:26.Jack and back in the 1920s, it won the Queen Alexandra stakes. They
:26:27. > :26:52.said at the time the horse is almost human. From all of us, good night.
:26:53. > :26:55.There are times in the life of a nation
:26:56. > :27:00.when the choices we make define the character of our country,
:27:01. > :27:05.times when people stand up and demand real, significant change.
:27:06. > :27:14.we have the chance to shape a brighter future for Britain
:27:15. > :27:19.and I believe we have the vision and the plan to do it.