:00:09. > :00:16.Welcome. The top stories: Pushing the boundaries of medical research.
:00:17. > :00:21.How a broke through by a team in Southampton is giving hope to this
:00:22. > :00:26.chronically ill boy and his family. Shutting down southern safety fears.
:00:27. > :00:30.The rail industry's leading expert says the union's concerns are
:00:31. > :00:33.unfounded. Calls for a rethink over this camera that is catching
:00:34. > :00:45.thousands of hospital visitors. A pioneering genetic test
:00:46. > :00:45.developed by doctors in Southampton could
:00:46. > :00:46.help patients with rare diseases pinpoint
:00:47. > :00:49.the root of their problems. The test's already helped
:00:50. > :00:51.an 11-year-old boy from Dorset. Matthew Knight suffered from one
:00:52. > :00:53.infection after another Doctors were able to boost Matthew's
:00:54. > :00:57.immunity to help him Since he was a baby,
:00:58. > :01:08.he's been in and out of hospital with a range
:01:09. > :01:11.of different infections. Doctors knew he had a rare immune
:01:12. > :01:13.deficiency but didn't know exactly Endless tests and blood tests
:01:14. > :01:19.and x-rays and scans and everything. It was a long haul waiting
:01:20. > :01:23.and finding out exactly how he was going to be treated
:01:24. > :01:27.because they really didn't Recently, Matthew was treated
:01:28. > :01:32.for a hip infection The family agreed to take
:01:33. > :01:38.part in a medical trial. Researchers there have developed
:01:39. > :01:41.a test that can go deeper than ever before in to our genetic make-up
:01:42. > :01:43.and pinpoint precisely Some have compared what we are doing
:01:44. > :01:52.at the moment in genomics to the man I think we are moving now
:01:53. > :01:56.into reality of delivering tests that we wouldn't have
:01:57. > :01:59.thought possible a decade and a half And with Matthew's case,
:02:00. > :02:03.we were able to turn a result and give the family information
:02:04. > :02:05.that they have been What we did find out was that
:02:06. > :02:11.you have 3.2 billion letters in your DNA and for me to have
:02:12. > :02:15.what I have, I have four missing. From the tests done
:02:16. > :02:22.in the lab, Matthew's faulty He's now getting the right treatment
:02:23. > :02:27.to boost his immune system and says he finally feels
:02:28. > :02:31.like a normal 11-year-old. Now the work in Southampton is part
:02:32. > :02:34.of a wider genome project going on hospitals around
:02:35. > :02:36.the country to create a test for all genes
:02:37. > :02:40.associated with disease. And it's not just for patients
:02:41. > :02:42.with rare conditions like Matthew. They are also developing tests to
:02:43. > :02:45.detect the cause of common cancers. The NHS says in time the project
:02:46. > :02:48.could transform the way A cyclist who killed a pedestrian
:02:49. > :02:59.in an argument about riding a bike on the pavement has been
:03:00. > :03:02.sentenced to just under three and a half years
:03:03. > :03:04.in prison for manslaughter. 69-year-old Roy Galvin was walking
:03:05. > :03:06.with his wife in Gosport last September when he got
:03:07. > :03:09.into the row with Duncan Snelgrove. Snelgrove pushed him, causing him
:03:10. > :03:14.to fall backwards and hit his head. There've been more developments
:03:15. > :03:23.in the Southern Rail strike, following the publication
:03:24. > :03:26.of a report into the issue The Chief Inspector of Railways says
:03:27. > :03:30.it is safe for drivers rather than conductors
:03:31. > :03:34.to operate train doors. The unions have
:03:35. > :03:36.dismissed his research. Our Transport Correspondent
:03:37. > :03:41.Paul Clifton has more. This latest report included tests
:03:42. > :03:43.on Southern Railway, on the precise routes
:03:44. > :03:46.through West Sussex on which The report was written
:03:47. > :03:51.by the most senior safety Driver only operation can be
:03:52. > :03:56.operated safely in compliance with the law on Southern Railway
:03:57. > :03:58.only and we have told Aslef The safety inspectors ran
:03:59. > :04:07.tests on the Horsham They looked at union claims that
:04:08. > :04:12.cameras on trains were unsafe Deficiencies were found at some
:04:13. > :04:20.stations, so Southern The inspectors looked
:04:21. > :04:25.at whether cameras could see small They also looked at leaving
:04:26. > :04:30.the door cameras running This offers clear safety
:04:31. > :04:36.benefits compared with But the drivers union
:04:37. > :04:41.is pressing ahead with next It says the two sides
:04:42. > :04:47.are on different planets. The reality is there has been no
:04:48. > :04:52.real move to address the fundamental issues that are at the heart
:04:53. > :04:54.of the deal. It's about the imposition
:04:55. > :04:58.of a system of breaking Every official report,
:04:59. > :05:04.every statistic I have ever read on driver door operation says
:05:05. > :05:08.it is safe, but the RMT union called to day's report a total whitewash,
:05:09. > :05:20.which proved this safety authority Both sides, it seems,
:05:21. > :05:25.are in no mood for compromise. An MP's stepped into the row
:05:26. > :05:27.about a controversial bus lane camera near the QA
:05:28. > :05:29.hospital in Portsmouth. Penny Mordaunt's asked the council
:05:30. > :05:33.to rethink how it operates the camera after more than three
:05:34. > :05:38.and a half thousand people The camera was installed in July
:05:39. > :05:42.and within the first 11 weeks fines totalling nearly
:05:43. > :05:47.?124,000 were issued. Between October and December fines
:05:48. > :05:52.totalled another 87 thousand pounds It's a camera that's been called
:05:53. > :06:04.a cash cow and unfair. It was meant to deter nonhospital
:06:05. > :06:07.users from using the bus lane as a short cut,
:06:08. > :06:11.but because you cannot see the sign clearly,
:06:12. > :06:14.it's actually penalising hospital If you approach this
:06:15. > :06:18.junction from the north or the south car park,
:06:19. > :06:20.then the signing here is obscured so people don't actually noticed
:06:21. > :06:24.there's a bus lane as you turn left And as you go through there,
:06:25. > :06:29.there's a camera, which would then Andrew is one of more than 3500
:06:30. > :06:35.drivers who have been caught. He received the fine only two days
:06:36. > :06:41.after his terminally Although the council has
:06:42. > :06:49.since let him off the ticket, on compassionate grounds,
:06:50. > :06:51.he says the system is unfair. I think it's immoral
:06:52. > :06:53.that they do that. People here are coming
:06:54. > :06:56.here for treatment or to take relatives, or visit relatives,
:06:57. > :06:58.and it's quite immoral that people Where you've got cameras in the city
:06:59. > :07:02.that are creating very, very high levels of fines,
:07:03. > :07:04.that should be reviewed And in this instance, clearly,
:07:05. > :07:08.those who have been fined had suggested that the signage could be
:07:09. > :07:12.improved, and I think that's probably the sensible thing
:07:13. > :07:16.for the council to do. Motoring experts say the issue
:07:17. > :07:20.in Portsmouth is not unique. In Preston recently,
:07:21. > :07:22.a bus lane was actually switched off after two weeks of a camera looking
:07:23. > :07:26.at a bus lane and catching people. And the reason they stopped
:07:27. > :07:28.that was that they realised that there were, that the signage
:07:29. > :07:31.it wasn't adequate. So they decided that they would stop
:07:32. > :07:34.putting fines in place, they would reassess the site,
:07:35. > :07:36.and look at the signage And that's what we'd
:07:37. > :07:41.like Portsmouth to do. Portsmouth City Council says
:07:42. > :07:43.that the current signs do comply However it does recognise there have
:07:44. > :07:49.been a large number of fines issued so it's now speaking to the hospital
:07:50. > :07:53.trust to see if any additional signs or road markings on the approach
:07:54. > :08:04.to the bus lane can be put in place. A monumental sculpture
:08:05. > :08:06.of a soldier has been created in Dorset and it's
:08:07. > :08:10.made entirely out of scrap metal. The six metre high soldier was put
:08:11. > :08:13.together to mark the centenary It's made from a mix of items
:08:14. > :08:18.including car parts and spanners and took three and a half months
:08:19. > :08:33.to build. It is a commission for a local
:08:34. > :08:37.author who asked us to build a ghostly figure of a First World War
:08:38. > :08:39.soldier. This is what we have ended up with and I think it fits the bill
:08:40. > :08:42.spot on. Some sports news and
:08:43. > :08:43.Southampton say captain Jose Fonte has asked
:08:44. > :08:45.to leave the club. The 33-year-old Portuguese defender
:08:46. > :08:47.is the only survivor He wanted a longer term deal
:08:48. > :08:51.than the one which was on the table. Meanwhile, Portsmouth missed
:08:52. > :08:54.the opportunity to close the gap on the promotion places
:08:55. > :08:57.against League Two leaders Doncaster - our reporter
:08:58. > :09:07.Andy Moon watched the game. The night that was an opportunity
:09:08. > :09:10.for Portsmouth to lay down a marker turned into one of great
:09:11. > :09:16.frustration. They were really slow out of the blocks against Doncaster
:09:17. > :09:25.and John Marquis gave the hosts and there are deep -- early lead. An
:09:26. > :09:32.equaliser came from Naismith. There were two more goals from the home
:09:33. > :09:38.side. This one into the top corner and a volley into the corner. The
:09:39. > :09:41.manager was fuming afterwards and admitted he was frustrated with the
:09:42. > :09:45.performance his side must wait ten days now to play again.
:09:46. > :09:47.That's all from the South Today news team this evening.
:09:48. > :10:00.It is looking cold once again and temperatures down to minus six
:10:01. > :10:05.Celsius. A widespread frost on the cards and some freezing fog. Already
:10:06. > :10:08.in parts of the region, we have seen temperatures plunging to minus
:10:09. > :10:13.figures. A chilly start tomorrow. Some mist and fog first thing. We
:10:14. > :10:21.will see some sunshine and through the course of the day, it will be
:10:22. > :10:24.mainly dry with rain moving in. As we look ahead towards the rest of
:10:25. > :10:31.the week, high-pressure dominates our weather. Despite the high
:10:32. > :10:35.pressure in charge, we will stay -- see a good deal of cloud.
:10:36. > :10:39.Temperatures into double figures in some areas. Unsettled conditions
:10:40. > :10:44.over the weekend and a chance we could have drizzle here and there.
:10:45. > :10:50.In summary, a frosty start from most places and through the course of the
:10:51. > :10:54.day, the club will increase. Cloud increasing through the afternoon and
:10:55. > :10:59.by dusk, that rain starts to move on. There will be a good deal of
:11:00. > :11:01.cloud and some bright and sunny spells.
:11:02. > :11:03.creeping up by a notch or two, 10, maybe nine Celsius. Here is Louise
:11:04. > :11:15.with the national picture. Won't it cold and frosty this
:11:16. > :11:21.morning? The coldest night of the winter so far in England. Down to
:11:22. > :11:25.minus 8 Celsius. But widely, the temperatures below freezing. Through
:11:26. > :11:27.the night, cloud and rain, so temperatures for many holding up
:11:28. > :11:28.above