02/05/2016 Outside Source


02/05/2016

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Hello, I'm Ros Atkins, this is Outside Source.

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Scientists hail a "milestone" in understanding what

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New research gives a near-complete picture of the genetic mutations

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involved and could lead to fresh methods of treatment.

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For years this he has been a mystery, Now he's given

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an exclusive interview to Rory Cellan Jones and he says

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I am going to come in front of the camera wants and I will never, ever

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The BBC's been told that Zika virus could affect far more babies

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The first cruise from the US to Cuba in nearly 40 years has

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We are keeping a close eye on the English Premier League. It is

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Chelsea 0- two Tottenham. To quickly mention that the ball,

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this is the feed that we have from a pub in Leicester. That is a large

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group of anxious men, women and children. At the moment, that game

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is not going to the plan for Leicester. Chelsea are losing 2-0

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against Tottenham. If Tottenham if Chelsea draw

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on loose, Leicester have the title. We begin with a story

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of huge significance. Scientists say they have

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a near-perfect picture of the genetic mutations that

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cause breast cancer. Enjoying a spot of Bank Holiday

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Monday gardening, Vanessa Babbage But Vanessa has fought

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a long, arduous battle After extensive surgery,

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chemo and radiotherapy, she knows how devastating the disease

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and its treatment can be. It's actually worse

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than the cancer itself, because you are constantly ill,

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so they do try to help you to minimise the side-effects by giving

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you other drugs to help the nausea and things like that, so

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the treatment is very, very harsh. Scanners like this one are used to

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detect and monitor cancerous tumours once they've already developed,

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but to understand the underlying causes of cancer, scientists have

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had to go much deeper, to the level of DNA,

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to try and work out what happens An international team of scientists,

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led by the Sanger Institute in Cambridge, examined all 3 billion

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letters in the genetic code of every What they've found has transformed

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the understanding of what happens Getting a comprehensive collection

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of information, including the mutations that are causing cancer,

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tells us something about why that cancer is going wrong,

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why that cell is turning into a cancerous cell,

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and if you can understand that, you can understand the causes

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of the cancer, and then you can This opens up the possibility

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of much greater individualised treatments for cancer,

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targeting each of the mutations. That's already happening with some

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treatments, like the drug Herceptin, but experts believe this

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could be a big step forward. What this study might

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achieve is finding better treatments, matching

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them better to women. By understanding the causes that

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underline the biology of different types of the disease,

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we might be able to match better treatments and offer them things

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that are more likely to work for Back at home, Vanessa Babbage

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is moving on with her life after cancer, and she is optimistic that

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science is starting to make real headway in the fight

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against the disease. It gives people hope,

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because when people are affected by someone that they love

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and they have breast cancer, they hope for a better future

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for other women that are going to be This research has transformed

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the understanding of cancer, and offers the tantalising prospect

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it could prevent the disease This is the Australian

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businessman who says he created He's called Craig Wright

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and he's spoken to three media organisations -

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the Economist and us. Rory Cellan-Jones did

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the interview for the BBC - First, here's Craig Wright on why

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he'd rather be doing no interviews. It is my right to say I did

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something. Why do I have to take credit for its? Why? Wouldn't you be

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proud? Yes, but that doesn't mean they have to bounce around in front

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of TV cameras. It's been thought that the founder

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of Bitcoin will have amassed That would give him or her a net

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worth of about $450m. Now we know that the Australian Tax

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Office is taking an interest We have told them about the tax

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issues and implications. We put in everything but the auditors we were

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using, and a number of tax lawyers at the time. We had an internal

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audit and navigate back to the tax office so we could the right amounts

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of tax. Because the body really understands bitcoins very well, the

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timing or anything like that, it is still an ongoing matter. Lawyers are

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negotiating how much tax I will. -- Iowa.

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Next, here's a message for any journalists or award

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If anybody ever puts me up for an award, I would never accept the

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centre. If you put me for a Nobel Prize, put me up for some honour, I

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will never accept the scent from any of you for anything. I am going to

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do this once and once only. I am going to come in front of that

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camera wants and I will never, ever be on a camera ever again for any TV

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You'd have thought that this announcement might bring an end

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He has already set off a firestorm on the Internet. There is passionate

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community around bitcoin, people who know a lot about crypto currencies.

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They are all arguing if whether he is the real thing. They are saying

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it is not sufficient proof that he is provided. In the last 20 minutes

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was so we spoke to the Chief scientist of the bitcoin foundation.

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He was Sean proof by Doctor Craig Wright and he believes it, so that

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is quite an endorsement. Can you explain what that says in a way that

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we can understand? The proof that he has been giving to people is

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evidence that he has got the big -- digital signature that belonged to

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the Monaco used to set up the bitcoin transaction, the first one,

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back in 2009. You know that's nom de plume did that. He is saying he can

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reproduce that signature and verify that the private code that

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effectively only that person would have. People will try to pick that

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apart. Huge controversy raging amongst bitcoin enthusiasts. Some of

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the leading scientists who have seen the believe it. He is this man and

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what did he do if he did create bitcoin? He has been around in

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academic competing circles for quite a while working on this kind of area

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of crypto currencies. What he did was in 2008, if it is same, at paper

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was published on the Internet in a very obscure area of the Internet

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with these matters are discussed. A few weeks later the software to make

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it happen was released online. He has been public about being involved

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in bitcoin in one way or another. What is different is that he is

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claiming he is the man that did it, but he said he did have

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collaborators. We've talked about the Zika

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virus a lot recently - but the BBC has learned how it

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could be far worse than feared. Sarah Robbins said:

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"Scientists studying test-tube "mini-brains" have been astonished

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to see how fast the Zika virus kills brain cells" A couple of weeks

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after scientists said more than a quarter of the world's

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population live in areas at risk. The main risk is that Zika causes

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case of microcephaly - Estimates are that 1% of women

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who have had Zika during pregnancy will have a child with microcephaly

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But now leading doctors in Brazil say that as many as 20%

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of Zika-affected pregnancies will result in one of a range

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of other forms of brain damage They've been talking

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to the BBC's Wyre Davies. Perhaps some of the most interesting

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work on these mini brains is it shows how effective and destructive

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the Zika virus can be. Neuroscientists were shocked by what

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they discovered, a huge reduction in growth of this rebuttal cortex, the

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crucial outer layer of the brain. We were all astonished by the fast

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effect. We saw cell death within three days. Within six days, some

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parts are completely gone. Here's Julia Carneiro in Rio

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on the steps that are being taken Lots of work is being done on many

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fronts. Researchers are trying to find out vaccine for Zika. The

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government, all of the states across the country, are trying to avoid

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more people getting did, but the virus is spreading in Brazil and in

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many other countries and it is a very grave situation, especially for

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pregnant women. The initial assessment, the first studies coming

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night are trying to find an answer to the question how many women who

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have Zika during pregnancy Google want to have babies with

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microcephily? The initial and that suggested might be around 1%. What

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the scientists are saying is that this number may be higher because it

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is not just microcephily that may be caused by Zika. There are other

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neurological problems involved and it might be that one in every five

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children born to a mother who had Zika during her pregnancy has some

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kind of problem. That might be a hearing problem, and eyesight

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problem, convulsions later on in life. These doctors are also saying

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it is very important to keep following the development of these

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children, at least in the first two years of their lives to see what

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will happen because as many people have been saying in the medical The

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Disappeared that microcephily might be the tip of the iceberg. The

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English Premier League is at the sharp end of the season and that oil

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is down to this, Tottenham are away at Chelsea. That is the Leicester

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City fans watching the game. They know it Tottenham don't win, the

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team, the most improbable champions in decades. You can tell that it is

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not going for them. Tottenham are winning 2-0. Stays like that, it

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will go down to them playing against Everton on Saturday.

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A man has been shot dead by police in Kent. If followed investigations

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into a man who was beaten to death in his home in a burglary last

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month. Armed officers took part in a preplanned operation in relation to

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them death of the 73-year-old man in Biddenden in March this year. Shots

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were fired during the incident. One man was fatally injured at the scene

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and a firearm has been recovered. Formal identification of that man

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has not yet taken place but the family of a man officers wanted to

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locate in connection with the murder in Biddenden have been informed. The

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matter has now been referred to the Independent Police Complaints

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Commission, as is mandatory for all police shootings.

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Our lead story is that scientists say they have a near-perfect picture

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of the genetic events that cause breast cancer.

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There is a continuation of fighting in Aleppo in Syria. John Kerry is in

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Geneva trying to salvage a crumbling ceasefire. In the Democratic

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Republic of Congo, thousands of people have been attending the first

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day of commercial -- official commemorations for Papa Wemba. As

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body is lying in the Parliamentary building and will there be taken

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later to his family home for the public to view. A British firm has

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admitted the selling a humidifier disinfectant that killed around a

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hundred people in South Korea. This is the head of the company's South

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Korean division being attacked by relatives of victims as he

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apologised. crisis several times -

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well it's worsened. Its governor says it will NOT make

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a 400-million dollar repayment There had been negotiations with

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creditors but a deal wasn't cut. If we look back to the nature of the

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Puerto Rican economy, it is very uncompetitive. It has a very complex

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tax system. Its relationship with the United States makes it quite

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burdensome for companies from outside to settle and understand the

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system. If we look at the key turning point we can probably go

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back a decade and look at the exploration of section nine 36 of

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the internal revenue code, which is to provide special tax breaks for US

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corporations setting up organisations in Puerto Rico. When

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those exemptions on corporate income tax were done away with, the economy

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went into a recession that we are seeing to this day and the local

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government decided to borrow heavily in order to balance its budget. That

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effectively is what brings us to the situation today whether government

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has been spending a lot more than it can afford and now it is in the

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position where it can't pay its creditors. There has been population

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movement. Because of Puerto Rico's special relationship of the United

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States as a territory, if citizens are US citizens and have the right

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to move freely in the United States. The population has pension shrinking

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rapidly in the last five years. We can see a situation now with a

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population of Puerto Rico will actually lose a generation, which

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would dampen the prospect of economic growth in the medium and

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long-term as the economic active predator weakens resettle on

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continental America. If the government does not have money to

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keep its basic services running, how can it respond to a special crisis

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and one of the key issues facing Puerto Rico now is the potential

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expansion of the Zika virus. Michelle, Hanley understand the

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economic and political relationship between Puerto Rico and America.

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Part of the problem is that it is a territory not a state. It is not

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eligible to applied for bankruptcy protection. In the city of Detroit

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had to file for bankruptcy, it was able to file to get assistance and

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to apply for certain rules as a state. This is not open to Puerto

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Rico. That is part of the debate and the application to Congress that at

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some point Congress should reassessed that. It should be

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allowed to re-negotiate with its creditors. Since it is not able to

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do that we are seeing the situation where the government is forced to

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say we can't make these debt payments. We have seen several

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repayments being missed. Thinking about the euro in crisis and the way

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analysts used to talk about contagion if certain debts were not

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dealt with, is there of the risk that what is happening in Puerto

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Rico could cross over to the main US economy and have consequences?

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People like to talk about Puerto Rico being America's Greece, but I

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think the comparison is more like with the city of Detroit, which had

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a manager that was brought in to manage the city back to health and

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take tough economic decisions. The question is, what will Congress do

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in the case of Puerto Rico? One lawmaker, Paul Ryan, was against the

:20:39.:20:41.

idea of taking control in Puerto Rico, but at the same time taking

:20:42.:20:46.

fiscal control out of the hands of the territory. Something has to be

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done. A lot of people are pushing for this idea to give them some kind

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of work around the roof so it can apply for some kind of bankruptcy

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detection and work at another solution. Whether Congress agrees to

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that, that is what the talk is at the moment.

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Next, airships! They are being reinvented by one British company.

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This hangar has remarkable history. Some of the largest aircraft ever to

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take to the skies were built here. That was almost a century ago that

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inside now a new airborne giant is taking place. This is the error land

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of ten. It is 90 metres long, longer than a super jumbo. It contains

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28,000 cubic metres of helium and it can stay in the air for five days.

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It was created by hybrid air vehicles for the US military as a

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high-flying spy in the sky but the project was cancelled, so the

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company's engineers brought back all the kit and decided to develop it

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for themselves. It is a mixture of the plane, helicopter and airships.

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It is a lifting body shape, it has gas inside it and its engines can

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trust air up, down, left and right degree of flight. What is it

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actually like to fly? We are cruising over the centre of London.

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I have the normal flight instruments. The test pilot is

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finding out in this simulator. You can feel the inertia of the

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aeroplane aloft. You make small control in Britain before the clap

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to respond. It is a bit like steering the ship. Hybrid air

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vehicles think that it can be used for a huge variety of tasks from

:22:52.:22:57.

disaster relief to tourism. It says the aircraft is almost ready to take

:22:58.:23:00.

to the skies in Britain for the first time.

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He's no stranger to incendiary comments -

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today Donald Trump has taken aim at China, saying their raping

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the US, whilst criticising their trade policy.

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We have a 500 and dollar deficit, trade deficit, with China. We were

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going to turn it around. We have the cards. We are like the piggy bank

:23:26.:23:30.

that is being robbed. We have a lot of power with China. If China

:23:31.:23:35.

doesn't want to fix the problem in North Korea we say, fixed the

:23:36.:23:39.

problem because we can't allow China to continue to rape our country and

:23:40.:23:44.

that is what the doing. It is the greatest theft in the history of the

:23:45.:23:50.

world. I have been speaking about this and how it is seen in China. If

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you look at the figures, China and the US has a huge trade deficit. In

:23:56.:24:00.

the first two months of this year the trade deficits between the two

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countries reached 57 billion US dollars. This is the kind of

:24:07.:24:15.

interesting, easy rhetoric to sell to the voters, that China is ripping

:24:16.:24:19.

off the US. He has been repeating this line for many months. He used

:24:20.:24:27.

this very derogatory word today. He feels like China is devaluing the

:24:28.:24:33.

currency. The liberally. That is one of the speculations. The reality is

:24:34.:24:39.

more complicated. The reason why Chinese currency is devaluing is

:24:40.:24:43.

partly because Chinese policymakers might want to make China's export

:24:44.:24:50.

more competitive, but also its reflects an economic domestic

:24:51.:24:55.

reality is that a lot of capital is leaving the country. That is to do

:24:56.:25:01.

value that currency. Looking at the economics, the two countries are

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having a more complicated economic relationship than ever. When Donald

:25:07.:25:11.

Trump speaks, the people in China care? Some do. A lot of the Chinese

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observers are quite sophisticated and they know this this is China

:25:17.:25:23.

bashing. Ever since President Nixon visited China in 1972, China has

:25:24.:25:30.

been a focal point in every American election. This is not exceptional,

:25:31.:25:35.

at all. It is getting tense and English Premier League. Let's look

:25:36.:25:39.

at the pub in Leicester. If Tottenham don't beat Chelsea,

:25:40.:25:44.

Leicester City will win the championship. Chelsea have a goal

:25:45.:25:53.

back. It is 1-2 at Stamford Bridge. If it stays like that, Leicester

:25:54.:25:57.

will be champions today. We will keep an eye on it.

:25:58.:26:05.

Time to check out some high impact noteworthy weather worldwide. Let's

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start in North America. We have had an explosion of thick cloud across

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parts of the deep South. This is the focus for further potentially

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flooding

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