Browse content similar to 13/05/2014. Check below for episodes and series from the same categories and more!
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The first arrest on suspicion of murder in the case of Claudia | :00:00. | :00:09. | |
Lawrence. The chef who went missing five years ago. Claudia vanished | :00:10. | :00:15. | |
after work in York and despite numerous public appeals has never | :00:16. | :00:18. | |
been found. Now, police have arrested a 59-year-old man and are | :00:19. | :00:22. | |
searching two houses. We will bring you the latest on the most | :00:23. | :00:25. | |
significant breakthrough on the case in five years. Also tonight: The | :00:26. | :00:28. | |
International Criminal Court is to examine allegations that British | :00:29. | :00:33. | |
forces carried out abuses in Iraq. The head of AstraZeneca claims new | :00:34. | :00:37. | |
medicines could be delayed by a proposed Pfizer takeover. Nigeria's | :00:38. | :00:42. | |
missing schoolgirls. Now, the Nigerian government says it's ready | :00:43. | :00:45. | |
to talk with the extremists who took them. How a ruling in Europe could | :00:46. | :00:49. | |
force search giants like Google to get rid of old or embarrassing | :00:50. | :00:52. | |
information about you on the internet. Tonight, on BBC London. | :00:53. | :00:58. | |
Head-to-head, our two biggest airports ramp up rival proposals for | :00:59. | :01:00. | |
a new runway. Banned from teaching for life, the former Head who spent | :01:01. | :01:04. | |
thousands of public cash on personal expenses. | :01:05. | :01:24. | |
Good evening and welcome to the BBC News at Six. A 59-year-old man has | :01:25. | :01:29. | |
been arrested on suspicion of murdering the missing university | :01:30. | :01:34. | |
chef, Claudia Lawrence. She disappeared five years ago. Miss | :01:35. | :01:37. | |
Lawrence vanished from her home in York and despite police appeals and | :01:38. | :01:43. | |
national publicity campaigns, led tirelessly by Claudia's father, | :01:44. | :01:46. | |
there has been no significant intraebg through in the case, until | :01:47. | :01:50. | |
now. Police are now searching a property in North Shields and one in | :01:51. | :01:54. | |
York. Danny Savage is there for us. What more can you tell us? This | :01:55. | :01:57. | |
evening the BBC understands the man under arrest on suspicion of | :01:58. | :02:00. | |
murdering Claudia Lawrence is Michael Snelling. He is linked to | :02:01. | :02:04. | |
this property here in York and another in North Shields that was | :02:05. | :02:08. | |
searched today. The disappearance of Claudia has to be one of the most | :02:09. | :02:11. | |
high profile missing persons inquiries that is ongoing in the UK | :02:12. | :02:15. | |
at the moment. For half a decade people here have been baffled about | :02:16. | :02:18. | |
what happened to her. Today, it appears this inquiry has taken a | :02:19. | :02:23. | |
giant step forward. Claudia Lawrence, missing, presumed | :02:24. | :02:27. | |
murdered. Until now, there have been no significant arrests in this case, | :02:28. | :02:32. | |
but today that changed. Police have begun searching a property in York. | :02:33. | :02:38. | |
Detectives removed bags of belongings, and could also be seen | :02:39. | :02:42. | |
around the rear of the house making notes and setting up equipment. This | :02:43. | :02:46. | |
happened as police announced they had arrested a 59-year-old man from | :02:47. | :02:51. | |
the city on suspicion of murdering Claudia. Neighbours have been | :02:52. | :02:54. | |
watching as the house became the focus of close scrutiny. Just | :02:55. | :03:01. | |
surprised, not shocked. Surprised. You don't envisage somebody in your | :03:02. | :03:04. | |
street to be accused of something like that. There has been times | :03:05. | :03:08. | |
where it has been pretty dark. Outside Claudia's home, her best | :03:09. | :03:14. | |
friend Jen, spoke about the strain of the last five years. It's organic | :03:15. | :03:20. | |
in how you cope with. It I'm lucky, I can compartmentalise things. I | :03:21. | :03:23. | |
have coped quite well. Others haven't. Others have been quite | :03:24. | :03:29. | |
badly affected by the whole thing. After an extensive search for | :03:30. | :03:33. | |
Claudia, police treated her disappearance as murder. North | :03:34. | :03:37. | |
Yorkshire Police set up a crime unit which reviewed the case. Earlier | :03:38. | :03:41. | |
this year, un ie tified fingerprints were found at her house and a man's | :03:42. | :03:46. | |
DNA was discovered on a cigarette end in her car. Five years ago, | :03:47. | :03:51. | |
Claudia Lawrence disappeared from her home city of York... The | :03:52. | :03:56. | |
breakthroughs formed part of a Crimewatch appeal on the fifth | :03:57. | :04:00. | |
anniversary of Claudia's disappearance. It had requests for | :04:01. | :04:05. | |
help in tracing this car. The feeling is the inquiry gained | :04:06. | :04:10. | |
momentum since then. Resulting in today's developments. This | :04:11. | :04:15. | |
afternoon, a house 80 miles away in North Shields was also searched as | :04:16. | :04:21. | |
part of the investigation. It was Claudia Lawrence father who has been | :04:22. | :04:25. | |
at the forefront of the campaign to find out what happened to her. Where | :04:26. | :04:30. | |
are you Claudia? Are you safe? Is someone holding you? Have you been | :04:31. | :04:35. | |
hurt even, of course, are you alive? He is said to be encouraged by | :04:36. | :04:43. | |
today's progress. Police have partially boarded up Mr Snelling's | :04:44. | :04:47. | |
home here had in York with police officers standing guard. The BBC | :04:48. | :04:52. | |
understands he was arrested in in the north-east of England today and | :04:53. | :04:55. | |
a car was seized as well. He remains in custody this evening. Danny | :04:56. | :04:59. | |
Savage, thank you. Claims that UK forces abused Iraqi detainees are to | :05:00. | :05:03. | |
be examined by the International Criminal Court in The Hague. It will | :05:04. | :05:06. | |
be the first time the UK has been the subject of an inquiry by the | :05:07. | :05:10. | |
ICC. The Attorney General, Dominic Grieve, says the UK will co-operate | :05:11. | :05:14. | |
fully with the court, but completely rejects the allegations. Our defence | :05:15. | :05:21. | |
correspondent, Jonathan Beale, is at the Ministry of Defence. How | :05:22. | :05:24. | |
embarrassing is this for the Government and the armed forces? | :05:25. | :05:27. | |
It's embarrassing for the government when they signed up to the | :05:28. | :05:31. | |
International Criminal Court I don't think they felt they would be the | :05:32. | :05:33. | |
subject of any kind of investigation. They join the likes | :05:34. | :05:38. | |
of Afghanistan, central Central African Republic to be under this | :05:39. | :05:40. | |
examination. The first stages of an ICC process. Hardly, shining beacons | :05:41. | :05:47. | |
of democracy. The allegations, there are 250 page dossier, they are | :05:48. | :05:51. | |
serious, no doubt about it. We heard about individual cases of of abuse. | :05:52. | :05:56. | |
Soldiers have been found guilty of carrying out abuse in Iraq and | :05:57. | :06:00. | |
Abbas. This says it was systematic. Hundreds of cases. That politicians, | :06:01. | :06:05. | |
senior commanders knew about it. There is anger here as well as | :06:06. | :06:10. | |
embarrassment here at the Ministry of Defence. They believe the lawyer | :06:11. | :06:13. | |
involved has tried to prove it in British courts. Has not been | :06:14. | :06:18. | |
successful. It is a victory for him in the first stage. The hope is it | :06:19. | :06:21. | |
gets no further. This preliminary examination will be the end of the | :06:22. | :06:24. | |
process. There won't be a full inquiry investigation by the the | :06:25. | :06:29. | |
ICC. OK. Jonathan Beale, thank you very much. The boss of AstraZeneca | :06:30. | :06:36. | |
says new medicines could be delayed if the company is en -- taken over | :06:37. | :06:44. | |
by the US pharmaceutical giantifieder. He made the claim | :06:45. | :06:48. | |
before a committee of MPs which is scrutinising what would be the | :06:49. | :06:49. | |
biggest ever foreign takeover of scrutinising what would be the | :06:50. | :06:53. | |
British company. The boss of Pfizer has defended the firm's track record | :06:54. | :07:00. | |
through the -- though has conceded there would inevitably be some job | :07:01. | :07:05. | |
cuts. Flash photography. MPs want to know if they can trust him. Ian Read | :07:06. | :07:14. | |
has been with Pfizer for 35 years. He says he will honour pledges on be | :07:15. | :07:25. | |
jobs and research. 2,000 people how many will be employed five years | :07:26. | :07:28. | |
from now? I will come back once we complete the accusation - Two years | :07:29. | :07:34. | |
from now, how many? Once we have completed One year from now, how | :07:35. | :07:37. | |
many? Is A substantial number will be employed. We do not take these | :07:38. | :07:43. | |
decisions likely. Mr Read admitted that overall job numbers could fall | :07:44. | :07:46. | |
if the deal goes through. He insisted that his pledge to bring | :07:47. | :07:51. | |
investment to Britain still stood. Let us put aside the legally | :07:52. | :07:55. | |
binding. I'm here today to make those commitments. I intend to | :07:56. | :08:00. | |
honour those commitments. The Pfizer board voted on those commitments. | :08:01. | :08:04. | |
For AstraZeneca this goes deeper than simple pounds and pence. The | :08:05. | :08:08. | |
company say it is will do better by retaining its independence. Or or | :08:09. | :08:25. | |
Pascal Soriot Turned the business around. One of our medicines was | :08:26. | :08:29. | |
delayed and essentially was delayed because in the meantime our two | :08:30. | :08:35. | |
companies were involved in saving taxes, or saving costs. To him | :08:36. | :08:39. | |
today, I pushed him on the commitments AstraZeneca was making | :08:40. | :08:44. | |
to scientific research in the UK. We have very, very deep roots in this | :08:45. | :08:49. | |
country. Our commitment is 10 years, 20 years, 30 years. Our commitment | :08:50. | :08:54. | |
is forever as long as we are an independent company. Bosses of the | :08:55. | :08:57. | |
two drugs companies came here to Westminster today to lay out their | :08:58. | :09:01. | |
case before MPs. It will now be down to the Government to decide if it | :09:02. | :09:05. | |
wants to play tough and intervene if it can or use softer powers of | :09:06. | :09:10. | |
influence. Will it be more carrot or stick? As if they haven't quite had | :09:11. | :09:15. | |
enough. Both men will be back tomorrow to face another Commons | :09:16. | :09:19. | |
committee, this time on science. Once these highly political days are | :09:20. | :09:24. | |
over, Pfizer will then consider increasing its offer to try and seal | :09:25. | :09:31. | |
this most tricky of deals. A teacher who was stabbed to death in her | :09:32. | :09:34. | |
classroom died from "shock and haemorrhage" following an injury to | :09:35. | :09:37. | |
her neck, an inquest has been told. Ann Maguire was attacked during a | :09:38. | :09:41. | |
Spanish lesson at Corpus Christi Catholic College in Leeds last | :09:42. | :09:46. | |
month. A 15-year-old boy is due to go on trial later this year accused | :09:47. | :09:50. | |
of murder. A woman who claims she was sexually abused by Rolf Harris | :09:51. | :09:55. | |
when she was 13 has today denied claims that their relationship began | :09:56. | :09:59. | |
years later and was consensual. The court saw a letter and cards from | :10:00. | :10:02. | |
Rolf Harris in which he said there was an affair. Under | :10:03. | :10:04. | |
cross-examination his alleged victim admitted asking the entertainer for | :10:05. | :10:09. | |
?25,000, but denied threatening to go to the papers if she didn't get | :10:10. | :10:11. | |
?25,000, but denied threatening to the money. Rolf Harris denies all | :10:12. | :10:16. | |
the charges. The Nigerian government says it's prepared to explore all | :10:17. | :10:20. | |
options to secure the release of over 200 schoolgirls that were | :10:21. | :10:24. | |
kidnapped over three weeks ago. Earlier, it had said it would not | :10:25. | :10:28. | |
talk to the Islamist terrorists who have taken them, Boko Haram. Some of | :10:29. | :10:32. | |
the schoolgirls have now been identified by receipt arrives a | :10:33. | :10:40. | |
video release by their captors. Our World Affairs Editor has travelled | :10:41. | :10:46. | |
to Maiduguri in Borneo, the region from where the girls were taken. | :10:47. | :10:52. | |
Some of the girls have been identified. There has been a little | :10:53. | :10:54. | |
movement in the efforts to get them back. After the scornful message | :10:55. | :10:59. | |
today yesterday by Boko Haram's leader, Abubakar Shekau, that they | :11:00. | :11:02. | |
would only give the girls back in exchange for captured Boko Haram | :11:03. | :11:07. | |
militants, a government minister has said they will try and get talks | :11:08. | :11:11. | |
underway. It hasn't worked in the past, but it could now. In the skies | :11:12. | :11:20. | |
above us in north-easts Nigeria, American surveillance planes have | :11:21. | :11:23. | |
started operating, searching for any sign of the girls. There is still no | :11:24. | :11:26. | |
indication the Niger an government is stepping up its efforts. This is | :11:27. | :11:32. | |
Maiduguri Airport, it serves the capital of a state which is fighting | :11:33. | :11:37. | |
a major insurrection. You might expect the apron here to be packed | :11:38. | :11:42. | |
with military aircraft. Not a bit of it. I asked a local Senator why so | :11:43. | :11:49. | |
little was being done? The international community must put | :11:50. | :11:52. | |
pressure on the government because, on their own, left to them, they | :11:53. | :11:56. | |
don't care because it is not their own people who are dying. Hence the | :11:57. | :12:05. | |
fury in places like the town of Gamboru, attacked last week by Boko | :12:06. | :12:11. | |
Haram. The local governor went to visit it, we came with him. The | :12:12. | :12:16. | |
destruction was appalling. The governor came here to offer help and | :12:17. | :12:20. | |
money, but the survivors are working themselves up into a frenzy of anger | :12:21. | :12:24. | |
that the Nigerian government should be doing so little to fight Boko | :12:25. | :12:34. | |
Haram. The governor is not elected. The government does not help us. | :12:35. | :12:40. | |
They have let us down. There was no calming them. The governor was lucky | :12:41. | :12:46. | |
to get away unhurt. This is pretty extraordinary. The governor and all | :12:47. | :12:50. | |
of the rest of us are being thrown out of here by the anger of the | :12:51. | :12:55. | |
crowd. We are having to get back to our cars pretty quickly. All this | :12:56. | :13:02. | |
anger isn't surprising. People here feel utterly abandoned. They can't | :13:03. | :13:06. | |
understand why a world, which cares so much about the missing | :13:07. | :13:11. | |
schoolgirls, seems to care so little about the destruction of an entire | :13:12. | :13:18. | |
town. John Simpson, BBC News, Borno State in north-eastern Nigeria. Two | :13:19. | :13:23. | |
people have died and seven are seriously injured after a coach | :13:24. | :13:27. | |
crash in Cornwall. It happened at lunchtime just outside Looe when the | :13:28. | :13:30. | |
bus, which was carrying more than 50 pensioners on a day trip from | :13:31. | :13:37. | |
ex-mouth, hit a wall. Jon Kaye is at the scene where the crash happened | :13:38. | :13:41. | |
for us now. I understand in the last hour the coach driver has been | :13:42. | :13:44. | |
arrested? That is right. This is the coach we are talking about. It | :13:45. | :13:49. | |
crashed just before 1.00pm this afternoon. The windscreen has been | :13:50. | :13:52. | |
smashed out. There are scrapes all along one side. The police have been | :13:53. | :13:55. | |
looking at the markings on the road. Trying to work out exactly what | :13:56. | :13:59. | |
caused this crash. They believe that the coach hit, first of all, a | :14:00. | :14:03. | |
hedge, further up the hill, then smashed against the wall. 50 people | :14:04. | :14:08. | |
on board, pensioners on a day trip to Cornwall, most of them managed to | :14:09. | :14:13. | |
walk off. Many had to be taken to a village hall to be treated there. | :14:14. | :14:17. | |
They were triaged. The more seriously injured were airlifted | :14:18. | :14:19. | |
from the scene to hospital in Plymouth. One lady died in hospital | :14:20. | :14:25. | |
and another woman died actually of her injuries on board the coach | :14:26. | :14:28. | |
during the afternoon. We have heard tonight that a 57-year-old man, the | :14:29. | :14:31. | |
driver of this coach, has been arrested. He has been taken to a | :14:32. | :14:37. | |
police station and being questioned on suspicion of causing death by | :14:38. | :14:40. | |
dangerous driving. Fee Owen ya. Jon Kaye, in Looe in Cornwall, thank | :14:41. | :14:47. | |
you. The time is 6. 14pm our top story. A man has been arrested on | :14:48. | :14:50. | |
suspicion of murder in the case of Claudia Lawrence, the chef who went | :14:51. | :14:53. | |
missing five years ago. Still to come: How our body clock affects our | :14:54. | :14:58. | |
overall health and our response to drug treatments. Later on BBC | :14:59. | :15:03. | |
London. Why some flood victims in Surrey are accusing Thames Water of | :15:04. | :15:08. | |
failing to protect their properties. And, Tim Sherwood is sacked as | :15:09. | :15:13. | |
Tottenham's manager. We ask who could be next for the White Hart | :15:14. | :15:15. | |
Lane hotseat. Healthy women with low-risk | :15:16. | :15:27. | |
pregnancies will be encouraged to give birth in specialist units led | :15:28. | :15:30. | |
by midwives rather than hospital maternity wards, under new | :15:31. | :15:32. | |
guidelines for England and Wales. The National Institute for Health | :15:33. | :15:35. | |
and Care Excellence says new evidence suggests that midwife-led | :15:36. | :15:38. | |
units are as safe as labour wards led by doctors, and that home births | :15:39. | :15:41. | |
with a midwife are safe for women having their second baby. Here's our | :15:42. | :15:44. | |
Health Correspondent, Branwen Jeffreys. | :15:45. | :15:51. | |
Natalie had her second baby just last night, cradling little FTN | :15:52. | :15:57. | |
ready to head home with the new addition to the family. She chose a | :15:58. | :16:02. | |
midwife-led unit in hospital and had her first baby and labour ward but | :16:03. | :16:07. | |
told me she wanted a different experience. He came so much | :16:08. | :16:14. | |
quicker. I didn't need any drugs this time whatsoever and that is all | :16:15. | :16:17. | |
down to being in this environment, just being able to let go and | :16:18. | :16:24. | |
letting the baby come out. Many women may now be advised a | :16:25. | :16:30. | |
midwife-led unit is just as safe because the birthplace study into | :16:31. | :16:34. | |
low risk women has led to new guidelines. It looked at the risk of | :16:35. | :16:38. | |
complications for their first baby. In a doctor led labour ward it was | :16:39. | :16:46. | |
5.3 per thousand births. In a stand-alone midwife unit the rate | :16:47. | :16:50. | |
was 4.5, for a homebirth 9.3 although that falls for a second | :16:51. | :16:55. | |
baby. Deciding where to have your baby is an intensely personal | :16:56. | :17:00. | |
choice. Some women will want the experience of a midwife-led units, | :17:01. | :17:07. | |
others will prefer the reassurance of a traditional hospital ward, just | :17:08. | :17:09. | |
in case anything goes wrong during labour. At the Chelsea and | :17:10. | :17:14. | |
Westminster Hospital, midwife and Doctor units are next to each other. | :17:15. | :17:20. | |
Some women have to transfer when there are complications or when the | :17:21. | :17:21. | |
pain becomes too great. That's what there are complications or when the | :17:22. | :17:27. | |
happened to Catherine with her first baby. She moved from a birth centre | :17:28. | :17:31. | |
to a labour ward, the only place she could get a pain relief injection. | :17:32. | :17:37. | |
Knowing it was available gave her peace of mind. It may be that you | :17:38. | :17:41. | |
have no plan to that pain relief and it is not a necessity but myself, I | :17:42. | :17:45. | |
went into the birthing unit thinking I would like to | :17:46. | :17:49. | |
went into the birthing unit thinking possible delivery but at some point | :17:50. | :17:53. | |
I wanted an epidural and that's fine. Whatever advice women are | :17:54. | :18:03. | |
given about maternity units, each will weigh up the risks and benefits | :18:04. | :18:07. | |
differently. The internet giant Google has been | :18:08. | :18:10. | |
told it must remove some information about individuals if it is out of | :18:11. | :18:14. | |
date or irrelevant in a test of the so-called right to be forgotten. The | :18:15. | :18:17. | |
landmark ruling was made at the European Court of Justice after a | :18:18. | :18:20. | |
Spanish man complained his privacy had been infringed. Our Technology | :18:21. | :18:22. | |
Correspondent Rory Cellan Jones is here. Does this mean people have the | :18:23. | :18:26. | |
right to take off the Internet information that they don't like? It | :18:27. | :18:32. | |
could do. This is all about the information thrown up by search | :18:33. | :18:36. | |
results from Google. The man at the heart of this found that whenever he | :18:37. | :18:41. | |
put his name into Google, an old newspaper story from the 1990s about | :18:42. | :18:46. | |
is how is being repossessed because of unpaid debts came up first. He | :18:47. | :18:51. | |
wanted it removed but Google the years said it couldn't do that, but | :18:52. | :18:57. | |
the highest court, the Court of justice is, said that as a principle | :18:58. | :19:02. | |
that it will enshrine in law. Anyone in principle could go to Google and | :19:03. | :19:07. | |
say, I don't like these results, you will have to remove them. There will | :19:08. | :19:12. | |
be some protection, but this will be a huge task for Google and other | :19:13. | :19:19. | |
search engines and raises all sorts of questions. | :19:20. | :19:22. | |
The Health Minister for Wales, Mark Drakeford, has issued a public | :19:23. | :19:25. | |
apology after a report described the care of elderly patients at two | :19:26. | :19:27. | |
Welsh hospitals as unacceptable with poor professional behaviour and | :19:28. | :19:30. | |
practice. Mr Drakeford said he was shocked by some of the findings | :19:31. | :19:33. | |
about the Princess of Wales Hospital, in Bridgend, and Neath | :19:34. | :19:35. | |
Port Talbot Hospital. Here's our Wales Correspondent, Hywel Griffith. | :19:36. | :19:43. | |
Her tablets scattered across the floor, a patient is left slumped and | :19:44. | :19:49. | |
sedated. These family videos show the care that Lillian Williams | :19:50. | :19:54. | |
received at her two local hospitals. After her death managers apologised | :19:55. | :19:58. | |
but the case triggered a review that has found a catalogue of failings in | :19:59. | :20:04. | |
the care of elderly patients. Her son says its findings only skim the | :20:05. | :20:09. | |
surface. We have always known this case was the tip of the iceberg. Has | :20:10. | :20:15. | |
never been any greater confirmation of the dozens of people who have now | :20:16. | :20:20. | |
come forward to confirm their relatives were also treated in the | :20:21. | :20:25. | |
most shocking manner. The report describes a sense of hopelessness | :20:26. | :20:29. | |
within these hospital walls, chaos when it comes to giving medication, | :20:30. | :20:34. | |
patients told to go to the toilet in their own bed. | :20:35. | :20:39. | |
patients told to go to the toilet in conditions were not as poor as those | :20:40. | :20:43. | |
in the Mid Staffordshire hospital scandal but they were shocked. It | :20:44. | :20:48. | |
was really the inconsistency so some patients were not getting the water | :20:49. | :20:53. | |
or the food or medication they needed. Last year some staff were | :20:54. | :21:02. | |
arrested at this hospital, so the others were suspended and managers | :21:03. | :21:07. | |
have apologised. I have said that I was ashamed, I said it to my board | :21:08. | :21:12. | |
last night and I said it today. There has to be a line in the sand. | :21:13. | :21:19. | |
We will not accept poor care. For the families who say their loved | :21:20. | :21:23. | |
ones have also suffered, an apology is empty without a resignation. They | :21:24. | :21:28. | |
say their campaign for answers will continue. | :21:29. | :21:31. | |
Some doctors are beginning to prescribe drug treatments to follow | :21:32. | :21:33. | |
the natural rhythm of our internal bodyclocks. Everything from our | :21:34. | :21:36. | |
blood pressure to hormone levels fluctuate according to the times of | :21:37. | :21:40. | |
day. This 24-hour cycle affects our alertness, energy levels and our | :21:41. | :21:44. | |
chances of falling ill. Now some doctors believe our internal body | :21:45. | :21:47. | |
clock can also have a profound effect on how we respond to drug | :21:48. | :21:51. | |
treatments. It's called the science of chronotherapy and it's gaining | :21:52. | :21:54. | |
increasing recognition. Fergus Walsh reports. | :21:55. | :22:01. | |
Day and night, we are governed by time. Despite every technological | :22:02. | :22:04. | |
advance, our bodies can't escape this biological cycle or circadian | :22:05. | :22:16. | |
rhythm. And this is our 24-hour body clock. It's partly driven by | :22:17. | :22:18. | |
hormones like melatonin, which peaks at night, helping us sleep. Or the | :22:19. | :22:22. | |
stress hormone, cortisol, which rises in the morning and keeps us | :22:23. | :22:26. | |
alert. These natural rhythms regulate our bodies and influence | :22:27. | :22:29. | |
our health, such as the increased risk of severe asthma or heart | :22:30. | :22:32. | |
attacks in the early-morning, to late afternoon being the period our | :22:33. | :22:43. | |
muscles are the strongest. It is dawn at Manchester Royal Infirmary | :22:44. | :22:47. | |
and Crystal is having blood taken. It will be analysed to establish the | :22:48. | :22:50. | |
best time of day to administer treatment for her rheumatoid | :22:51. | :22:57. | |
arthritis. It is painful every day. It limits how much I can move | :22:58. | :23:01. | |
around, if I can kneel down, what I can go out and do. So if they had a | :23:02. | :23:15. | |
drug that just worked, that would change everything. Chronotherapy is | :23:16. | :23:17. | |
the science of treating patients according to their body clock. With | :23:18. | :23:20. | |
rheumatoid arthritis, it means timing drugs so they dampen the | :23:21. | :23:24. | |
immune system for a few key hours. If we can make sure those medicines | :23:25. | :23:27. | |
are given at just the right time, we can hit the disease process and the | :23:28. | :23:31. | |
drug washes out the system, leaving the patient drug-free for most of | :23:32. | :23:34. | |
the day and therefore less likely to get side-effects. In Paris, | :23:35. | :23:39. | |
chronotherapy is now being used for some cancer patients. Philippe used | :23:40. | :23:45. | |
to suffer severe nausea and exhaustion until some drug infusions | :23:46. | :23:53. | |
were switched from day to night. The doctor pioneering cancer treatment | :23:54. | :23:55. | |
by body clock says early clinical trials have been promising. The | :23:56. | :24:02. | |
chronotherapy is reducing toxicity of treatments, increasing the | :24:03. | :24:04. | |
quality of life for the patients because it is respecting the | :24:05. | :24:07. | |
circadian rhythm of the patients, and also it is improving the | :24:08. | :24:17. | |
survival. Chronotherapy is still in its infancy but gaining ground as | :24:18. | :24:20. | |
more doctors recognise the importance of our body clock. | :24:21. | :24:28. | |
And you can find out more about how your body clock changes through the | :24:29. | :24:35. | |
day at bbc.co.uk/bodyclock. Time for a look at the weather. Here's Tomasz | :24:36. | :24:45. | |
Schafernaker. Today I got soaked. Yesterday evening, no doubt some of | :24:46. | :24:51. | |
us were caught out in the downpours won after the other but the chance | :24:52. | :24:55. | |
of catching a shower will lower as we go through the course of the | :24:56. | :25:00. | |
evening. By the time we get to around eight o'clock in the | :25:01. | :25:03. | |
evening, most of the showers will be across these eastern areas of the | :25:04. | :25:09. | |
country. It should be a dry end to the day, and by the time we get to | :25:10. | :25:12. | |
the small hours of the morning it is looking clear and call for many of | :25:13. | :25:21. | |
us. Temperatures could be as low as minus one degree in Scotland. | :25:22. | :25:28. | |
Wednesday starts fine for most of us, lots of sunshine around. Then | :25:29. | :25:33. | |
later in the day, some cloud and rain will drift into Scotland and | :25:34. | :25:37. | |
Northern Ireland, whereas in the bulk of England and Wales it should | :25:38. | :25:41. | |
be fine with temperatures reaching 19 Celsius. On Thursday, we have | :25:42. | :25:51. | |
settled conditions, translating to some sunshine with the odd shower | :25:52. | :25:56. | |
developing across the heart of the country, but look at those | :25:57. | :26:03. | |
temperatures in the south-east reasoning -- rising to 21 Celsius. | :26:04. | :26:07. | |
That will be the trend for the weekend. Either time we get to | :26:08. | :26:14. | |
Sunday, we could even be talking about 25 degrees. For the rest of | :26:15. | :26:18. | |
the week, dryer and warm with some sunshine around but the nights be | :26:19. | :26:24. | |
chilly. That's all from the BBC News at six | :26:25. | :26:26. | |
so it's goodbye | :26:27. | :26:28. |