01/02/2016 BBC News at Six

For the first time British scientists are given the green light

to genetically modify a human embryo.

They will be altering the human blueprint in the first days

It is important for understanding aspects of human genetic disease,

understanding, just basic biology, it has been used in semi-different

contexts now. -- so many different contexts now. If this had come

earlier, could have provided answers, could have saved a lot of

heartache for me. to women who've struggled

with starting a family We'll be hearing about

the ethical issues involved. tackling the spread

of the Zika virus, the World Health Organisation

declares it a global health A new inquest begins into the death

of Cheryl James at Deepcut barracks England's junior

doctors will strike again out goes Manuel Pellegrini

and in comes Pep Guardiola, Scotland battens down the hatches

for the second time in a week, as Storm Henry sweeps across the

country, and a rush of signings as the transfer window draws to a

close. researchers have been given

permission to genetically the way a human embryo develops

in its earliest stages, though none will be allowed to grow

beyond a few days. Scientists based at the Francis

Crick Institute in London hope to find clues into why women

miscarry and improve success rates Critics say it is the first step

towards legalising designer babies. Our Medical Correspondent

Fergus Walsh has more. VOICEOVER: Creating human life in a

dish, scientists have been able to do that for decades. Now, they could

go a step further. Altering it genetically. Researchers in London

will be using donated embryos, left over from IVF treatment, which will

only be allowed to be developed for a few days, and never implanted in a

woman. It is the first time that a project like this has been approved

by a national regulator, it is really important for basic

understanding of basic biology, and it has potential benefits in terms

of better IVF treatment and avoiding things like miscarriages. Ehmer

endured for miscarriages, in the space of a year. For her, like many

women, the causes remain a mystery. -- Emma. I found it frustrating that

I never had answers as to why I kept miscarrying, if research had come

earlier, and could have provided answers, then it could have saved a

lot of heartache. This is a five-day-old embryo, already the

cells are beginning to the differentiate. Scientists will edit

the genes in the green cells, which will go on to form the foetus, but

how will they do it? Gene editing is cheap, simple and accessible to

scientists anywhere in the world, it is like a melee killer sat naff --

it is like a molecular satellite navigation, it uses molecular

scissors to snip through boats strands, switching off a full

teaching or enabling a healthy copy to be inserted, both techniques have

the potential to treat or even cure genetic diseases. For some, today's

decision is the slippery slope which will inevitably lead to designer

humans and eugenics. Gene editing is already being used to change all

types of life, in fact, that may raise more pressing concerns. It has

huge ramifications on the environment, in terms of insects and

animals and plants. And how you develop biological weapons. Those

are things to concentrate upon. People are hung up on the idea that

some people are going to create designer babies, it has never

happened and I don't think it will happen in the near future. It may

take years before this research leads to better fertility treatment

but across every field of science, gene editing is promising major

advances, improving human health is just a part of that.

STUDIO: The World Health Organisation is meeting to discuss

whether to declare a global emergency over the Zika virus, which

has been linked to brain abnormalities in thousands of babies

in Brazil. Officials have described its spread as explosive. Our Science

Editor, David Shukman, has sent this report from Recife in Brazil, the

city worst hit by the outbreak. VOICEOVER: A young woman, four

months pregnant, has just heard that she may be infected with the Zika

virus. An agonising glimpse into a nightmare here at the epicentre of

the outbreak. Another pregnant woman, who asked us not to show her

face, says she definitely has the virus. She has red eyes, a typical

symptom of Ziegler, and she is due to give birth in two months' time

and is waiting for the results of the test. -- a typical symptom of

the Zika TRANSLATION: I'm feeling worried, I have aches and a rash,

which are indicators of the virus. What makes everybody more anxious is

the uncertainty. What is so disturbing about what is happening

here is that the women are turning up with a lot of highly personal and

pressing questions which the doctors just cannot answer. Above all, what

damage can the Zika virus do to their babies? The painful moment

when test results are handed out. Evidence is growing that the virus

is to blame for the forming babies brains, but it is not certain, so

there is no way of predicting the impact. When you see the ultrasound,

something is wrong, you have to tell her, and then you know that after

you tell her, she will ask you many questions. If the child will be able

to walk, will be able to hear properly, will be able to see

properly. We do not know. Like several thousand babies in Brazil,

this baby was born with a small brain, unless she is rocked all of

the time, she becomes agitated. Her mother, Michaela D'Souza, is clearly

overwhelmed. It is not the moment to get pregnant, she is as, because so

far, nobody knows where the virus comes from. -- she says. All of this

adds to the urgency of killing the mosquitoes that carried the virus,

but reaching them is difficult, so from today, officials have a new

power, to break into homes, if they need to.

The key is public support. The authorities are harnessing the

Carnival is buried. A mosquito costume raises awareness of the

dangers. Anything to get people to join the fight against the insects.

-- the authorities are harnessing the Carnival spirit. All day as

rocks baby, she worries about how she cope. This glance shows that

there is some brain function, but nobody can tell how this crisis will

unfold. STUDIO: If you want to find out more

about the Zika virus, or you want advice if you are planning a trip to

the affected region, find out more on the website.

The European Council President has just announced he will table

proposals tomorrow for a new settlement between the UK and

Brussels. Donald Tusk says good progress has been made in talks on

proposed changes to Britain pot relationship with the European

Union. It comes after days of negotiations between between British

and European officials to agree a plan ahead of a summit of EU leaders

later this month. Here's our Deputy Political Editor, James Landale - I

should warn you his report contains flash photography. VOICEOVER: Every

year, at Dover and other ports and airports across the UK, hundreds of

thousands of EU citizens arrive to live and work. The government thinks

too many come, they want to deter them by reducing the benefits they

can claim while they are working. How to do that is what the Prime

Minister has been negotiating with Donald Tusk, man representing other

European Union countries. Any of them are afraid that citizens could

lose benefits unfairly. Both men are looking for compromise. The current

option is for a so-called emergency brake, this would allow the

government to restrict the benefits of EU migrants who have a job for up

to four years. But, the government can only do this when numbers are so

high that pressure was being put on public services. European Commission

says that threshold has already been met, so some people hope that they

can pull this break immediately after a referendum. The details of

who applies the welfare break, and when and for how long are still up

for negotiation. What seems to be on offer is a break that the Eurocrats

are still going to control, two years, four years, seven years, the

British people want to be in control of their borders, and how they

manage their employment practices. Today, tired British officials

headed back to Brussels for more talks. They hope there is a chance

of success but many in Brussels are focused on a different issue. The

entrance of EU workers into Britain is still very limited, that is not

the problem today, people are looking to their television, the

problem today... Workers from the EU coming in? No, the refugee crisis!

That is the problem. It is not just welfare rolls of the government is

looking to change, it wants greater protection for the City of London by

ensuring countries who do not use the euro can challenge decisions

made in the Eurozone. It wants more powers for Westminster and other

parliaments to block European Union laws and the UK out of greater EU

integration and it wants the European Union to be more

competitive, so it is easier to export goods and services from the

UK. Lots of detail for Tory MPs to discuss with the Prime Minister

today, officials and ministers spoke progress being made, but more hard

work to be done. I do not think we should provide a running commentary

about what is going on in the negotiations, it is

they are taking place and taking very seriously. -- taken very

seriously. Once the very seriously. -- taken very

deal, he will put that to the British people. What matters now is

what the rest of Europe things, once details are published tomorrow. The

decision to publish the details tomorrow is significant because it

suggests he is confident of getting some agreement with the rest of the

European Union, his proposals, which will be many pages and full of legal

recommendation, will be subject is good to need and opposition but he

and the Prime Minister will hope that at the big summit in a couple

of weeks' time that a deal can be done. STUDIO: Junior doctors in

England are to go on strike next week after talks with the Government

over new contracts failed to reach an agreement.

They'll walkout for 24 hours on Wednesday the tenth of February

The stoppage will be the second walk-out by junior doctors over

Our Health Editor Hugh Pym joins us from University College

The doctors have pulled back from a full on strike, what do we make of

that? It will certainly be less disruptive, the original plans would

have affected all forms of care at hospitals like this one, including

emergencies, that has never before happened in the history of the NHS,

what is blank now is a walk-out of routine and non-urgent care, which

junior doctors will still cover emergencies along with consultants.

That will still affect thousands of patients whose routine treatment

operations, outpatient appointments, will be postponed, as happened on a

similar day of action in January. Does it mean the two sides are

closer together? The answer is no, on one key issue, agreement has been

reached but on the issue of how much doctors are paid for working on a

Saturday, no agreement. The government would like to treat

Saturday like a normal working day. The British Medical Association

representing doctors say that is not possible because of unsocial hours.

No further talks at ACAS, the conciliation service, although it

has not been ruled out. A British woman, who took

her 14-month-old son to Syria to join the so called

Islamic State group, Tareena Shakil sent

messages to her family, insisting she wanted to die

a martyr, and allowed the toddler to pose for photographs,

wearing a balaclava. Sentencing her at Birmingham Crown

Court, Mr Justice Inman, said Shakil had known her son's

future would ultimately be

"as an IS fighter". A second inquest has

opened into the death of a young recruit at the Deepcut

army barracks in Surrey Private Cheryl James,

who was 18, was found with a bullet wound

to her head in November 1995. The original inquest recorded

an open verdict but that was quashed when new allegations

of abuse emerged. Here's our Home Affairs

Correspondent, June Kelly. VOICEOVER: Private Cheryl James had

just turned 18 when she died while on guard duty at Deepcut Barracks,

she was found with a single bullet wound to her head. Deepcut Barracks

then has been depicted as a place of bullying and fear, between 1995 and

2002, Cheryl James was one of four young soldiers to die there, all had

suffered gunshot wounds. For young soldiers to die there, all had

their families have been battling to find out the full facts of their

deaths. Cheryl's parents are the first to have a new inquest, among

the allegations it will examine, they claimed that Cheryl may have

been rates the night before she died. It is terrible, it is very

difficult. -- may have been it is your worst nightmare, you wish that

you had been there, so that you could have sorted it out. -- may

have been raped. There is no intention to look at an alleged

culture of sexual abuse at the barracks, why has it taken so long

to get to this point? In 1995, three weeks after she died, a brief

inquest recorded an open verdict. Her death was investigated by the

Royal Military Police. The investigation found no evidence

of any crime. In 2006, a review by a senior lawyer concluded that her

wound was probably self-inflicted. In 2014, her parents finally won the

right to have a new inquest after gaining access to all the material

available to police. Gerald's father was expected to be the first person

in the witness box today but there was a delay as new evidence came to

light. For the first time British

scientists get permission to modify And still to come -

those running the charity Kids Company are among those

blamed for its collapse And coming up on Reporting

Scotland at 6.30. Unless her husband proves he earns

enough to support their family. And the new dangers being faced

by salmon fishers on the Dee There's been a significant rise

in the number of people wanting medical advice about

gender reasignment - that's when people feel

they were born in the wrong body As you can imagine, it's

an emotional challenge and - it seems - even more

so if you are brought up Tonight we have the story of Romario

- he was born in Jamaica as a girl He fled to Britain to escape

a father who physically Declan Harvey of Radio 1's Newsbeat

joined him on a journey How does it feel packing your bag

and going back after seven years? Anxious.

A lot of emotions going on. Life is very different for Romario

since he fled to the UK seven years By taking hormones, he has

transitioned from female to male, an option still

unavailable in Jamaica. That would be the worst

packing ever. He'd been living there as a gay

woman but had suffered violence, It's my opportunity to just

close that book now. Jamaica has a reputation

for being hostile to gay They're not protected

by anti-discrimination laws, The thing about Jamaica,

it's not just about being a man, You have to be deemed

the head of the household. I remember the night

I ran away from my dad. Being in Jamaica was

constant survival. Trying not to be killed for being

gay, or a lesbian, transgender. Last year, campaigners

held their first ever gay They didn't march in the streets

but say being able to host an event is a sign of growing

acceptance. Gosh.

Walking into Judgment Day. Romario's father has been told

about his transition before their meeting but this

is the first time they have seen or spoken to each other

in almost a decade. I never used to think that something

like that was for real. Deep down, I always felt

like I wanted a son. You got what she wanted,

it just wasn't physically there. I can never make any promise

to refer to you as a he. After filming, to Romario's

amazement, his father posted a photo Another sign, perhaps,

of attitudes changing. And you can watch the full

documentary "Transgender -

Back to Jamaica" A brief look at some of the day's

other other news stories Storm Henry is battering its way

across Scotland with winds of over 80 miles per hour causing

damage and disruption. Many schools have been closed

and travel services cancelled. In Rosshire, the Cromarty Bridge

was closed to all vehicles except cars - after

a lorry was blown over. The BBC has learnt that five police

forces are investigating more than 1300 allegations of abuse

of inmates at detention and residential centres for young

people from the 1960s to the 1990s. The allegations relate to 11 centres

for troubled children and teenagers

across Northern England. Care homes in Northern Ireland

are to benefit from an additional The money, from the Health

and Social Care board, is aimed at the independent sector

and will be used to recruit staff for nursing homes and to provide

home care packages. Plans to give more powers to Wales

are so flawed Assembly Members A report by MPs says

an "extraordinary catalogue of failures" led to the collapse

last year of the charity, Kids Company, which received

millions of pounds of public funds. The Commons' Public Administration

committee blames those running the charity, auditors,

regulators and ministers. Here's our special

correspondent, Lucy Manning. Behind the scenes with Camila

Batmanghelidjh as Kids Company crumbled. Part of the deal is that I

stepped down as Chief Executive. Do you know what I need to become? An

ambassador! Filmed for a BBC documentary with money in envelopes

rushed out to clients, she has attempted to downsize the charity.

Defiant to the end. What is sorry for? I'm not sorry that I gave the

kids money. I'm not sorry that I bought the nice things. I'm not

sorry that I fought for them. I'm not sorry. The only thing I'm not

sorry about is I didn't raise enough money. She is blamed for being too

dominant and unaccountable with money lavished on favourites. The

charity's trustees including Alan Yentob were called negligent and he

is accused of failing in his duties. It is the duty of the trustees to

run the charity. They don't just float above and let others run it.

No matter how powerful a person is, however visionary, however much

money they are raising, they have to be held to account. The report also

blamed ministers who shouldn't have handed over money. It's believed

that the charity exaggerated the number of children it was helping

but it did accept that it adds some valuable work. The charity was

cleared valuable work. The charity was

survive. Last week, the Miller Batman gay ledge had

-- Camila Batmanghelidjh had this to say. The report doesn't inspire a

great deal of confidence. The company was described as

irresponsible. And you can watch the full

documentary "Camila's Kids Company: The Inside Story" this Wednesday,

at 9pm, on BBC One. It's football transfer deadline day

today but the headlines are being made, not by a player,

but a big managerial move. At lunchtime Manchester City

announced Manuel Pellegrini would be leaving the club at

the end of the season - and then within minutes said he's

being replaced as manager The Spaniard won a cabinet full

of trophies in a four-year stint at Barcelona and is currently

in charge at Bayern Munich. Andy Swiss is at the Etihad Stadium

in Manchester for us tonight. Not too many managers get appointed

five months in advance but not too many managers are like Pep

Guardiola. We knew he was coming to the Premier League but we didn't

know where. But now Manchester City have got their man. Looking for

trophies, look no further. Pep Guardiola, the manager that

everybody wants. Swapping Munich for Manchester. Man U up a

-- Manuel Pellegrini has not done badly but he has confirmed

speculation that come the summer he is packing his bags. I finish my

contract on the original date in June. I do not think it is good to

have the speculation. City announced Pep Guardiola it would replace him.

Once an outstanding player, now an outstanding manager. Under him

Barcelona 114 trophies, including three league titles, three Spanish

cups and the Champions League twice. He has continued a success with

Bayern Munich and his biggest fan says Manchester City have chosen

well. TRANSLATION: They will be very happy because he has never

disrespected anyone. He is very well mannered and polite. To use a

Catalan expression, he won't be taking anyone for a ride. City are

hardly struggling, second in the league but not -- out of the cups.

But he hasn't cracked it in Europe yet. This could potentially take

Manchester City to the next level. City revealed they first had

discussions with Pep Guardiola in 2012. As for Manuel Pellegrini, it

seems, some success wasn't quite enough.

Time for a look at the weather. Here's Louise Lear.

Storm Henry producing some beautiful, dramatic pictures but

also producing some damage already. So, the winds will continue to

strengthen through this evening and overnight. Drifting its way in from

west to east. We are going to see damaging gusts of wind. We will see

rain, sleet and snow mixed in. There could be localised flooding. Be

prepared for some disruption. Storm force winds still potentially there

during the morning rush hour. You can see, we have still got the rain

and snow and we have still got the wind. We will also see some pretty

strong winds following down towards the West of England as well. Coupled

with some sharp showers. A windy start across central areas. More

cloudy further south, a few isolated showers and windy here as well.

Really, the cause for concern is across central and northern

Scotland. Relentless rain could lead to localised flooding. Top

temperatures 6-10d. Into Wednesday, the remnants of Henry, still crossed

the spine of the country. We could see a frost but a good deal of dry

weather on Wednesday.