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It's being hailed as a big step forward in the fight | :00:00. | :00:00. | |
?50 million for a new research help in Cambridge. 4000 new homes in | :00:00. | :00:16. | |
Corby, but concerns about the scale of the development. And winter is | :00:17. | :00:21. | |
not finished with that yet. Try me later for a look at the weather | :00:22. | :00:23. | |
ahead. It's being hailed as a big step | :00:24. | :00:31. | |
forward in the fight The University of Cambridge has been | :00:32. | :00:34. | |
chosen as one of five hubs around Britain seeking new ways | :00:35. | :00:38. | |
to diagnose, treat Together, they'll form | :00:39. | :00:40. | |
a Dementia Research Institute thanks to ?250 million | :00:41. | :00:44. | |
of public money. That is another one of my mother | :00:45. | :00:48. | |
with my two cousins. Ian became his mother's carer, | :00:49. | :00:56. | |
Jean, who died aged 85, My mum, she sat in | :00:57. | :00:59. | |
the room, and said, And then, at the time, | :01:00. | :01:07. | |
you thought, crikey, You know, she hadn't | :01:08. | :01:12. | |
got a clue who I was. It's only going to be | :01:13. | :01:17. | |
on the increase. There's estimated 850,000 people in | :01:18. | :01:19. | |
this country who have It's only going to get worse over | :01:20. | :01:23. | |
the next ten, 15 years. These are the new labs, | :01:24. | :01:28. | |
let me show you. At the moment, they're in a state | :01:29. | :01:30. | |
of sort of basic refurb. Now at Cambridge | :01:31. | :01:34. | |
biomedical campus, The site chosen among five | :01:35. | :01:35. | |
in the country My lab works on understanding | :01:36. | :01:41. | |
the basic mechanisms of dementia and finding | :01:42. | :01:44. | |
new treatments. We are making very | :01:45. | :01:46. | |
good progress there. We bring in chemists and, | :01:47. | :01:48. | |
biophysicists, the very best of Cambridge, using state-of-the-art | :01:49. | :01:51. | |
techniques, we are really going to be able to use everything that | :01:52. | :01:55. | |
Cambridge has and its sort of spectrum of excellence | :01:56. | :01:58. | |
and just focus on dementia. And on top of that, we are going | :01:59. | :02:02. | |
to recruit scientists from around the world and we're looking | :02:03. | :02:05. | |
for absolute excellence, world leading scientists | :02:06. | :02:07. | |
to come and join us. On the left, another, | :02:08. | :02:09. | |
shrunk in size after the death The red areas, proteins that have | :02:10. | :02:14. | |
malfunctioned, Teams here working on treatments, | :02:15. | :02:18. | |
the new centre looking more into the causes, one day, | :02:19. | :02:24. | |
they hope to find a cure. The overall Institute's | :02:25. | :02:29. | |
mission is to understand the causes and particularly | :02:30. | :02:32. | |
at the earliest stages, when you are most likely to be able | :02:33. | :02:35. | |
to help people. We're getting about | :02:36. | :02:37. | |
13 million initially, but there is projected | :02:38. | :02:39. | |
more investment. It's to bring in great new | :02:40. | :02:41. | |
scientist, the world's leading and the best, to come | :02:42. | :02:44. | |
and tackle dementia. Ian has seen the devastating | :02:45. | :02:47. | |
effect of dementia. No family should go | :02:48. | :02:50. | |
through what has went through, Any advances in | :02:51. | :02:52. | |
research are welcomed. The charity Alzheimer's Research UK, | :02:53. | :03:01. | |
based in Cambridge, Its Chief Scientific Officer, | :03:02. | :03:03. | |
Dr David Reynolds, I asked him how significant | :03:04. | :03:08. | |
the new hubs were. It's really important because it | :03:09. | :03:15. | |
starts to move the pledge of the previous Government | :03:16. | :03:18. | |
and David Cameron for a global action plan | :03:19. | :03:21. | |
for dementia into reality. And therefore, we can actually start | :03:22. | :03:25. | |
to do that research, get that understanding and bring | :03:26. | :03:28. | |
those medicines to patients. What are you actually hoping will be | :03:29. | :03:32. | |
achieved with these the hubs? Are we talking about | :03:33. | :03:36. | |
better prevention, Most of the research that | :03:37. | :03:38. | |
will happen in the Dementia Research | :03:39. | :03:43. | |
Institute will be understanding the basic mechanisms | :03:44. | :03:45. | |
at the cellular level, so what causes brain cells | :03:46. | :03:47. | |
to die in these diseases. From that, you can | :03:48. | :03:51. | |
lead on to ways to prevent the disease and also treat | :03:52. | :03:54. | |
the disease with medicines. Are you concerned at | :03:55. | :03:58. | |
all about the impact that Brexit might have, | :03:59. | :04:00. | |
given that we don't know yet how movement | :04:01. | :04:02. | |
of people and work permits and that sort of thing | :04:03. | :04:04. | |
might pan out in future? It's really important that dementia | :04:05. | :04:07. | |
remains a priority for the Government after the | :04:08. | :04:09. | |
election, and Brexit may well be something | :04:10. | :04:13. | |
that could have an impact, and we are certainly very | :04:14. | :04:16. | |
concerned about that and are advocating that funding | :04:17. | :04:20. | |
for research, dementia, particularly for us, obviously, | :04:21. | :04:23. | |
is maintained through that. But we don't know what Brexit | :04:24. | :04:26. | |
will mean for research anywhere in the UK at | :04:27. | :04:29. | |
the moment, unfortunately. Of course, we do have a general | :04:30. | :04:33. | |
election coming up. What sort of messages | :04:34. | :04:36. | |
are you hoping to you from the main parties about | :04:37. | :04:39. | |
funding in the future? We are really hoping | :04:40. | :04:41. | |
that the main parties and, ultimately, whoever wins is | :04:42. | :04:44. | |
committed to biomedical research for dementia and more broadly, | :04:45. | :04:47. | |
because this country has a fantastic science base that helps | :04:48. | :04:51. | |
to understand diseases and bring medicines | :04:52. | :04:55. | |
to patients and it is important we don't lose | :04:56. | :04:57. | |
that And how much does this | :04:58. | :04:58. | |
sort of investment help establish Cambridge as a real | :04:59. | :05:03. | |
global scientific centre? Cambridge, as you know, | :05:04. | :05:06. | |
already has a world-leading university, and it is because of | :05:07. | :05:08. | |
those world-leading scientists that Cambridge has been selected | :05:09. | :05:11. | |
as one of the centres. And Cambridge will feed | :05:12. | :05:14. | |
into the rest of the work of the Dementia Research Institute | :05:15. | :05:17. | |
to tackle those big unknown questions that up till now we have | :05:18. | :05:20. | |
struggled to get good answers to, and hopefully the DRI | :05:21. | :05:23. | |
will help crack that. And it feels likea subject we're | :05:24. | :05:28. | |
talking about a lot more these days, Because people understand and are | :05:29. | :05:31. | |
aware of the impact of dementia, either on themselves | :05:32. | :05:37. | |
or their friends and family, it helps get | :05:38. | :05:40. | |
people engaged where they might participate in research, | :05:41. | :05:45. | |
for example, and it helps also to bring in funding | :05:46. | :05:47. | |
to solve the problems. Dr David Reynolds from Alzheimers | :05:48. | :05:53. | |
Research UK speaking earlier. An investigation is underway | :05:54. | :05:58. | |
in Luton after a suspected shooting. Police say there were called | :05:59. | :06:02. | |
at around 3:30pm this afternoon to Whipperley Ring, | :06:03. | :06:05. | |
where a man had been injured. An air ambulance took the man | :06:06. | :06:08. | |
to hospital for treatment. Witnesses are being asked | :06:09. | :06:11. | |
to contact police on 101. Plans have been submitted for a huge | :06:12. | :06:15. | |
extension The project on land | :06:16. | :06:17. | |
to the west of the town would involve more | :06:18. | :06:22. | |
than 4,000 new homes. If approved, it'll also include | :06:23. | :06:25. | |
a secondary and two primary schools, and two local centres with shops | :06:26. | :06:28. | |
and other facilities. There'll be employment opportunities | :06:29. | :06:31. | |
for more than 3,000 people. But residents in neighbouring | :06:32. | :06:34. | |
Rushden say the scheme's too big. If we are not careful, | :06:35. | :06:39. | |
a lot of the local towns Kettering is expanding in this | :06:40. | :06:42. | |
direction, with a warehouse development over there, Corby | :06:43. | :06:54. | |
is expanding in this direction, Desborough is expanding in this | :06:55. | :06:56. | |
direction, or they hope to, so where | :06:57. | :06:57. | |
does it all end? Now to the latest in our profiles | :06:58. | :07:02. | |
of the mayoral candidates He's promised to create a "modular | :07:03. | :07:04. | |
homes" factory in the Fens, building up to 20 homes | :07:05. | :07:09. | |
a day, if he wins. Businessman Peter Dawe is one | :07:10. | :07:12. | |
of seven hopefuls for the job of the county's first devolved | :07:13. | :07:15. | |
mayor, with increased powers over Mousumi Bakshi put Peter Dawe | :07:16. | :07:18. | |
in the mayoral hot-seat. Why should people vote | :07:19. | :07:33. | |
for Peter Dawe, what sets you apart I can see a very big picture, | :07:34. | :07:41. | |
I can see that there are solutions to a lot of the problems | :07:42. | :07:48. | |
in Cambridge, housing and transport, that actually don't need more | :07:49. | :07:52. | |
money than is available. Do you have a big idea, | :07:53. | :07:57. | |
one big vision that you would I believe that we can go | :07:58. | :08:00. | |
to micro cars, In our urban environment, we've got | :08:01. | :08:08. | |
to look at 21st-century solutions. Can you tell us how much money has | :08:09. | :08:12. | |
been put aside Tell us one thing that people | :08:13. | :08:15. | |
might not know about you. I was brought up in a council house, | :08:16. | :08:28. | |
son of a newsagent and I went out delivering newspapers | :08:29. | :08:32. | |
for the family at an early age. I'm coming in with several | :08:33. | :08:35. | |
visions about how to transform local government | :08:36. | :08:41. | |
in Cambridgeshire. I believe that councils | :08:42. | :08:46. | |
have completely lost the plot is bring 21st-century solutions into | :08:47. | :08:50. | |
it. And I can't see how the party | :08:51. | :08:57. | |
political system has got the ability Where is your favourite | :08:58. | :09:03. | |
place to go in Cambridge? I live just outside | :09:04. | :09:09. | |
Ely, I have the most And a sunset, where it's honeyed | :09:10. | :09:13. | |
in the morning, We'll be back with updates | :09:14. | :09:20. | |
during BBC Breakfast from 6:00am. Hello, turning much colder this | :09:21. | :09:42. | |
week. We have had this cold front pushing south, it had cleared now, | :09:43. | :09:47. | |
but behind it, colder but drier air coming down from the Arctic. So | :09:48. | :09:51. | |
clear skies tonight, cold wind blowing, but under this clear skies, | :09:52. | :09:55. | |
temperatures will drop further sharply. Some wintry skies but for | :09:56. | :09:59. | |
most it's right. Around freezing out in the countryside, Frost tonight, | :10:00. | :10:05. | |
damaging for some gardeners. Introduced it, some sunshine, bit of | :10:06. | :10:10. | |
a cold wind blowing, dry from most of the morning but some showers. | :10:11. | :10:15. | |
This could be heavy, somehow, sweet, thunder as well. Temperatures up to | :10:16. | :10:19. | |
nine or ten, but in the wind it will feel colder than that. On Wednesday, | :10:20. | :10:24. | |
more scattered showers, some heavy with some hail mixed in as well. | :10:25. | :10:29. | |
Thursday, warm front drifting down from the north, head of it, still | :10:30. | :10:32. | |
dry. It will bring some cite the warmer air for the end of the week. | :10:33. | :10:40. | |
A slightly frosty Bob Wright start to the morning. Friday, a lot of dry | :10:41. | :10:46. | |
weather, some sunshine around, but hit and miss. Temperatures by this | :10:47. | :10:50. | |
stage looking back-up. As with the ahead into the weekend, Saturday | :10:51. | :10:55. | |
looking dry but for Sunday and Monday some brain, especially on | :10:56. | :11:00. | |
Sunday, maybe every risk for bank audit Monday. | :11:01. | :11:02. | |
some rain. More with the national forecast now. | :11:03. | :11:06. | |
Good evening. It's been turning colder from the north so far today. | :11:07. | :11:12. | |
It's been cold enough for significant snow in northern | :11:13. | :11:15. | |
Scotland. This was mid afternoon. More recently it's been blowing | :11:16. | :11:19. | |
around over the tops of the mountains. Snow in April not | :11:20. | :11:24. | |
necessarily unusual but it's usually unwelcome. The colder air coming in | :11:25. | :11:28. | |
behind the front which clears towards the near continent, opening | :11:29. | :11:31. | |
the floodgates to this Coldstream of air all the way from the Arctic. | :11:32. | :11:36. | |
That cold air increasingly cold air will spread its way across all parts | :11:37. | :11:40. | |
tonight and will be with us tomorrow and Wednesday as well. A cold night | :11:41. | :11:44. | |
ahead of us. A widespread frost developing and further wintry | :11:45. | :11:47. | |
showers. Most in Scotland and the north-east of England too. Cold | :11:48. | :11:52. | |
winds as well. Maybe a few wintry showers in Northern Ireland and | :11:53. | :11:55. | |
Wales, maybe the odd few into the Midlands. Clear skies, windy and | :11:56. | :12:00. | |
cold. Major towns and cities not far from | :12:01. | :12:01. |