29/12/2017 BBC News at Ten

Snow, ice and strong winds have

disrupted many parts of the UK -

with more to come over

the New Year weekend.

There've been warnings

of treacherous driving conditions

in the worst-affected areas.

Several major cities in Iran are hit

by a wave of protests

against the government.

And the dog who's had

pioneering treatment

to save a leg from amputation -

experts hope to use the same

technique soon on people

Good evening.

Good evening.

Snow and ice have led

to another day of travel

disruption in parts of the UK.

Passengers at Glasgow

airport faced delays,

after heavy snow caused flights

to be suspended for a while.

There was snow too across northern

England and the southern Pennines.

The RAC has warned that driving

conditions will be very

difficult, if not impossible,

in the worst-affected areas.

Our correspondent

Judith Moritz reports.

Grounded at Glasgow -

flights at the city's airport

were suspended after snow

settled quickly overnight.

The airport reopened by mid-morning,

but managers have apologised

for the knock-on disruption

which was caused.

Temperatures plummeted to as low

as minus 12 Celsius in Scotland.

The ploughs were out,

shovelling industrial quantities

of snow on the M90 motorway

near Dunfermline, though it

wasn't enough to keep

all drivers on the road.

In towns and villages

nearby, the spades were

out to clear the way.

She's just come in for a packet

of cigarettes, and she's decided

to clear my front path away,

and that's community spirit for you.

Heavy snow also fell

in the north of England,

where a hundred gritters were sent

out onto the road network

to keep traffic moving.

The snow has been falling steadily

all morning across swathes

of northern England.

As predicted, it's been settling

most in areas like this,

just outside Huddersfield,

up here on the higher ground.

In Cumbria, hazardous

conditions left some vehicles

stranded on the A590,

and there were also delays

on other main roads.

Staff at the Highways England

control room in Wakefield

have been monitoring

the motorways and A-roads.

The next thing we're looking

towards is the threat of ice

for this evening and overnight,

we've got teams of gritters working

24/7, traffic officers patrolling

the network as well,

and obviously a team

here in Yorkshire and the North East

working from the control room

to make sure that that

impact's not too severe.

Drivers are advised only

to travel if necessary.

Judith Moritz, BBC News, Wakefield.

Anti-government protests have spread

to more cities in Iran ,

despite a crackdown

by the authorities.

Thousands of people have

taken to the streets

to protest over rising prices,

corruption, and the cost of Iran's

military involvement

in regional conflicts.

Wyre Davies reports.

These are extremely rare sights.

Iranian cities hit by large

anti-government protests.

This is the western

city of Kermanshah.

Despite the repressive

action of the police,

the protests have quickly

grown and spread.

Iranians have suffered tremendous

economic hardship in the last

decade with a huge fall

in living standards.

But what started as a protest

against rising prices has grown

into wide anger against strict

clerical rule and Iran's supreme

leader, Ayatollah Ali Khamenei.

There is seething discontent,

with Iranians spending

money on wars abroad,

on spreading Shiaism broad,

supporting Hezbollah abroad.

And that has changed the character

of the demonstration

into a political one,

undermining the whole

clerical regime now.

Iran's relatively moderate

president, Hassan Rouhani,

has promised the benefits

of economic growth after

an international deal

to limit its nuclear activities.

But those promises have

failed to materialise.

Britain will be watching

developments closely.

On a recent visit,

the Foreign Secretary Boris Johnson

raised the detention of the British

woman Nazanin Zaghari-Ratcliffe,

held in an Iranian jail

for more than 600 days.

It's become a serious issue

between London and Tehran.

It's too early to say if the regime

is under serious threat.

These are the biggest protests

in Iran for almost a decade

and the government will greater

force if it feels

it is losing control.

Wyre Davies, BBC News.

A huge fire at an office

and restaurant complex in the Indian

city of Mumbai has killed at least

14 people including young women

attending a birthday party.

The blaze erupted after midnight

in the popular Kamala Mills

compound, and engulfed the building

in just half an hour.

The New York fire department says

the blaze that killed 12 people,

including four children,

in the Bronx area of the city

appears to have been caused

by a child playing with a stove.

Investigators believe

an unattended 3 -year-old boy

accidentally started the blaze -

described as the deadliest

in the city for at least 25 years.

The Labour peer, Lord Adonis,

is stepping down from his role

advising the government

on major infrastructure projects.

In a draft resignation letter,

the former transport secretary

criticised Theresa May's approach

to Brexit, and claimed that she has

become the "voice of Ukip"

within the Conservative party.

Two men have been charged with

preparing an act of terrorism. They

appeared by video link before

Westminster Magistrates' Court and

were remanded in custody.

Researchers in Scotland,

who saved the leg of a dog

using a new technique to grow bones

in a laboratory, say they now hope

to try it on human beings.

The dog, Eva, would have had her leg

amputated had it not been for this

pioneering treatment.

The team at Glasgow University say

the first human trials are due

to take place in three years' time.

Our science correspondent Pallab

Ghosh has this exclusive report.

Eva!

There's no holding her back,

but last year Eva's front right leg

was broken in a road accident.

Her vet tried everything,

but nothing worked.

Her entire leg was

going to be amputated.

Well, nine, ten months, she'd been

unable to get out and have walks,

anything other than go out

to the toilet.

But to Fiona Kirkland's delight,

her dog was saved by an experimental

bone-growing technique.

It's absolutely fantastic.

We're just so pleased

to have our dog back,

fit, active, healthy.

Eva's vet showed me the problem.

The blood supply to the edges

of the bones has failed,

so it wasn't able to heal the break.

The scientists coated the dead areas

with their artificial bone,

and after just six weeks,

it was completely mended.

The artificial bone mix was made

at Glasgow University.

It consists of sterilised chips that

are coated with bone cells

and a chemical that make them grow,

rather like a fertiliser.

Well, clearly, we want to look

at treating more dogs and possibly

even cats who have had broken bones,

but also other areas we can help

these veterinary patients,

so things like joint fusion,

where they've had a tendon injury

and they need their joint held

together so they can walk properly.

The researchers are so amazed

at the success they've had

in treating Eva they want to try out

the technique on people.

They plan to be the first

researchers in the world to grow

bone in their lab and put it

into a patient in three years' time.

And these are the people that

could be most helped.

It's 20 years since Princess Diana

brought the issue of landmine

victims to the world's attention.

Their limbs usually

have to be amputated.

Landmine campaigners are funding

the new research so it can be used

to grow some of their bone back

and attach an artificial leg.

Well, if they are able

to have a prosthetic limb,

it would make all the difference

to their life, being able

to provide for their family,

instead of having to be a burden

on their family.

It's been a happy outcome

for Eva and her owners.