02/05/2016 BBC News at Six


02/05/2016

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Scientists hail a "milestone" in understanding what

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New research gives a near-complete picture of

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and could lead to fresh methods of treatment.

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The US Secretary of State insists any peace deal in Syria must include

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the besieged city of Aleppo, the focus of recent intense fighting.

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And Government plans to reform tipping, to see more money

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Scientists say they have a near-perfect picture

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of the genetic mutations that cause breast cancer.

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The study, in the journal Nature, has been described as

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a hugely significant moment in cancer research.

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It's hoped the analysis could help unlock new ways of treating

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Here's our Health Correspondent, Dominic Hughes.

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Enjoying a spot of Bank Holiday Monday gardening, Vanessa Babbage

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But Vanessa has fought a long, arduous battle

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After extensive surgery, chemo and radiotherapy, she

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knows how devastating the disease and its treatment can be.

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It's actually worse than the cancer itself,

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because you are constantly ill, so they do try to help you to

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minimise the side-effects by giving you other drugs to help the nausea

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and things like that, so the treatment is very, very harsh.

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Scanners like this one are used to detect and monitor cancerous tumours

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once they've already developed, but to understand the underlying

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causes of cancer, scientists have had to go much deeper,

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to the level of DNA, to try and work out what happens

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An international team of scientists, led by the Sanger Institute

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in Cambridge, examined all 3 billion letters in the genetic code of every

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What they've found has transformed the understanding of what happens

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Getting a comprehensive collection of information, including the

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mutations that are causing cancer, tells us something about why that

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cancer is going wrong, why that cell is turning

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into a cancerous cell, and if you can understand that,

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you can understand the causes of the cancer, and then you can

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This opens up the possibility of much greater individualised

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treatments for cancer, targeting each of the mutations.

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That's already happening with some treatments, like the drug

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Herceptin, but experts believe this could be a big step forward.

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What this study might achieve is finding

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better treatments, matching them better to women.

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By understanding the causes that underline the biology

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of different types of the disease, we might be able to match better

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treatments and offer them things that are more likely to work for

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Back at home, Vanessa Babbage is moving on with her life after

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cancer, and she is optimistic that science is starting to make real

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headway in the fight against the disease.

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It gives people hope, because when people are affected

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by someone that they love and they have breast cancer,

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they hope for a better future for other women that are going to be

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This research has transformed the understanding of cancer,

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and offers the tantalising prospect it could prevent the disease

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In talks in Geneva to try to save the ceasefire in Syria,

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the US Secretary of State John Kerry said foreign powers were "getting

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There's been a two-month pause in hostilities in the country,

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but the last ten days have seen an upsurge of violence.

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Mr Kerry said a renewed ceasefire must include

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the besieged city of Aleppo, where more than 250 civilians

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Our correspondent Barbara Plett-Usher has been travelling

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War has returned to Syria's largest city after two

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The air strikes on a hospital last week thrust the carnage

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back into the spotlight, but hundreds of civilians have

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been killed in the past ten days of fighting.

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The Syrian military says it is targeting jihadists,

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But the lines between such groups and other rebels in Aleppo

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If the cease-fire breaks down here, it may crumble across the country.

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The crisis triggered emergency meetings in Geneva,

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the city that's been hosting Syrian peace talks.

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America's top diplomat came here to try to salvage the truce.

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We are engaged in an effort with all of the members

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of the international Syrian Support Group,

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and with Russia particularly, in an effort to restore that

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cessation of hostilities in those places where it has been most

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There is no excuse for not finding, again, a reinvigorating

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and reinstalling and re-implementing what has been the only strong

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message the Syrian people have heard from all of us.

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Mr Kerry is urging Moscow to push its Syrian ally to stop

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But the most he announced he was a joint agreement agreement

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to strengthen the monitoring and implementation of the truce.

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So they are wrestling with a formula to bring quiet back to Aleppo.

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Are there will be intensive talks involving the Russians

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Mr Kerry said there should soon be greater clarity about the details of

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But the bigger question is whether Damascus

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and Moscow are serious about the UN path to peace,

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or whether they are using it to make military gains on the ground.

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Barbara Plett-Usher, BBC News, Geneva.

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A 36-year-old man has been shot dead during an operation

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Officers were called to a property near Maidstone last night,

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The pre-planned operation was connected to the suspected

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murder of Roy Blackman, who was beaten to death

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during a burglary at his home last month.

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The Independent Police Complaints Commission is now investigating.

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A 21-year-old man has appeared in court accused of planning

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The government is considering new laws on what happens

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The proposals include plans for a customer code that would make

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tipping more transparent and ensure that all tips do go

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It follows major criticism of some restaurants for failing

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to pass the money on, as our business correspondent,

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Unlike some other national restaurant chains,

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Gourmet Burger Kitchen doesn't apply an automatic service charge,

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nor does it deduct any administration fees from tips.

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If the Government has its way, that will be the norm.

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I think it is only fair that if a customer leaves a tip

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with the intention of it being given to the staff member,

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Now, the Business Secretary, Sajid Javid, is proposing that

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gratuities are passed on in full to service staff.

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At the same time, he wants restaurants to make it much clearer

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And he is proposing a new code, but says he will pass legislation

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if companies continue to withhold tips from staff.

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It's got to go to the people that you intend it to go to.

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It also has to be voluntary for good service.

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That is what everyone wants to see and that is why

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But some critics say tipping has had its day.

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I think it is time that we scrapped all forms of service charges

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and tipping and simply increased waiters' salaries to make

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The British public feel very uncomfortable when it comes

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to tipping, they don't know where the money is going to.

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It is also bizarre, in the 21st century,

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that we have this weird servile relationship with waiters.

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The general public are less sure about that.

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I would like to think it is going to the waiters

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and waitresses and the cooks and that it is shared

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equally, but I'm not sure whether it is or not.

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Everyone who gets tips, it just gets split at the end of the day.

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I don't think that's fair because I might work

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The restaurant business is very competitive and margins

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But if restaurateurs are forced to hand over part or all

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of the tips their staff get, it may drive some of them

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Ultimately, it's the dining public who will decide whether and how much

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An Australian computer scientist has ended years of speculation,

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saying he is the creator of the controversial

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Dr Craig Wright, who lives in London,

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showed the BBC evidence that he launched the currency

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Dr Wright is believed to hold hundreds of millions of dollars

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of bitcoins, which are a virtual currency

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transferred via the internet, and which can be exchanged

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This exclusive report from our technology correspondent

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In an office in London, a mystery that has been an intranet

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obsession for seven years is about to be solved.

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So you are going to show me that Satoshi Nakamoto is you?

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If that is true then Dr Craig Wright is the reason there is a new

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Bitcoin is a currency invented on the Internet and

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designed to operate outside the control

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Its value and its reputation has been

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widely used by criminals has been the world spends.

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It was back in 2008 that someone calling themselves Satoshi Nakamoto

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published a paper on the Internet describing a plan for Bitcoins. It

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was the following year that he introduced the software allowing the

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currency to take shape. Ever since, Satoshi Nakamoto 's Mac precise

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identity has been a mystery. Last year there was a speculation about

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Craig White, a Dutch Craig Wright, an Australian scientist. Now he he

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has confirmed that he is Satoshi Nakamoto. Some people will believe

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and some people won't. I don't really care. The evidence published

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by Dr Wright to prove that he is Satoshi Nakamoto 's been met with

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some scepticism, but at a Bitcoin conference in New York today, a

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leading figure said he was convinced. I met with him in London.

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He fits the kind of person that I was interacting with back in 2010.

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And he provided some cryptographic proof. It was a private key from the

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very first Bitcoin. Craig Wright will not reveal how rich Bitcoin has

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made him, that says he doesn't want to be a figurehead for the currency.

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I don't want money, I don't want fame or adoration. I just want to be

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left alone. I'm going to come in front of the camera once, and I will

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never ever be on the camera ever again. If he is to be believed, he

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is a modern day Midas, the man who conjured new money out of thin air.

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It is a remarkable achievement, but having emerged from the shadows,

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Craig Wright, or Satoshi Nakamoto wants to disappear once more.

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This Thursday, voters across most of England and Wales will be able go

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to the polls to elect their Police and Crime Commissioners.

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PCCs were introduced in 2012, with the aim of making police forces

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accountable and more responsive to public needs.

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But voting then suggested widespread apathy for the new role.

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Our home editor Mark Easton reports from the campaign trail

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32 million people get the chance to vote for their Police and Crime

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Commissioner in England and Wales on Thursday.

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Here in Northamptonshire, three candidates are up for

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I want to maintain front line policing.

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The first thing I'll do is reduce the cost

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of the office of Police and Crime Commissioner.

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Local people should help decide where police resources

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The idea behind PCCs is the elected commissioner would be

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impartial, setting police priorities for all the people, whatever their

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But there are concerns that candidates should

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Of the 188 PCC candidates across England and

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Turn-out last time was a miserable 15%, a little higher in

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But hopes that the public would start to

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embrace this new elected official with the power

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to hire and fire the Chief Constable, well let's say this

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election could be seen as a referendum on the PCC idea.

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To be honest, I don't really know what's going on.

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Do you think people are excited about it?

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I don't think they are excited about it at all.

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Their previous PCC, Tory Adam Simmonds, is standing

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Praised by the Home Secretary for helping cut crime, he was

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criticised locally for increasing his office budget while the police

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I spent 30 years in business from a technology point

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of view, so I want to see body-worn video

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cameras, the latest technology - that will make the difference.

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We have lost over 105 police officers in

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Northamptonshire since 2010 and at the same time

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crime has doubled over the past two years, so we need a better

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We have seen over the years that the established political

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parties have failed to address the problems of

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Ukip is the party to change that, and so am I.

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Turnout is likely to be higher this time than last

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because in many places PCC elections coincide

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But whatever the local situation, there seems there is

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plenty of scope for increasing public enthusiasm.

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Mark Easton, BBC News, Northamptonshire.

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And finally, Leicester City didn't quite manage it yesterday,

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but tonight there's another opportunity for them to clinch

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If Spurs fail to beat Chelsea this evening, Leicester will

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Andy Swiss is in Leicester, where fans are gathering

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in pubs around the city to watch the match.

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Yes, welcome to the local hero pub, just a stone's throw from

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Leicester's Stadium. Among the fans who will be watching the TV rather

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nervously tonight is lifelong Leicester supporter Lee job. Thank

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you for joining us. If Tottenham don't win, Leicester are champions.

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How confident are you that? It's got to happen tonight, surely. If you'd

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asked me two days ago, I would have wanted it to happen at Old Trafford

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yesterday. Let's just get it on and enjoy the rest of the week, and

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party on to next week. I don't want to go to Chelsea needing points.

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Let's get it out the way and enjoy Champions League. No one has

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mentioned that because everyone is so wrapped up in the potential title

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win. What a story, the Champions League, the whole Leicester story

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itself... The whole city is either anxious or buzzing. Everyone has

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different feelings about the situation. Let's get it out the way,

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take it to Everton and a massive party at the weekend. What would it

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mean to you to see your beloved Leicester be crowned champions? I

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don't know if there is a word for it. It needs to be added to the

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dictionary! I know it is positive, and a million times better than

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great. It should be a nervous nights a Leicester fans, but could be a

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very special one.

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