Browse content similar to 02/05/2016. Check below for episodes and series from the same categories and more!
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Scientists hail a "milestone" in understanding what | :00:00. | :00:00. | |
New research gives a near-complete picture of | :00:00. | :00:10. | |
and could lead to fresh methods of treatment. | :00:11. | :00:15. | |
The US Secretary of State insists any peace deal in Syria must include | :00:16. | :00:18. | |
the besieged city of Aleppo, the focus of recent intense fighting. | :00:19. | :00:24. | |
And Government plans to reform tipping, to see more money | :00:25. | :00:27. | |
Scientists say they have a near-perfect picture | :00:28. | :00:52. | |
of the genetic mutations that cause breast cancer. | :00:53. | :00:55. | |
The study, in the journal Nature, has been described as | :00:56. | :00:57. | |
a hugely significant moment in cancer research. | :00:58. | :01:00. | |
It's hoped the analysis could help unlock new ways of treating | :01:01. | :01:03. | |
Here's our Health Correspondent, Dominic Hughes. | :01:04. | :01:10. | |
Enjoying a spot of Bank Holiday Monday gardening, Vanessa Babbage | :01:11. | :01:13. | |
But Vanessa has fought a long, arduous battle | :01:14. | :01:18. | |
After extensive surgery, chemo and radiotherapy, she | :01:19. | :01:23. | |
knows how devastating the disease and its treatment can be. | :01:24. | :01:27. | |
It's actually worse than the cancer itself, | :01:28. | :01:32. | |
because you are constantly ill, so they do try to help you to | :01:33. | :01:38. | |
minimise the side-effects by giving you other drugs to help the nausea | :01:39. | :01:45. | |
and things like that, so the treatment is very, very harsh. | :01:46. | :01:49. | |
Scanners like this one are used to detect and monitor cancerous tumours | :01:50. | :01:52. | |
once they've already developed, but to understand the underlying | :01:53. | :01:59. | |
causes of cancer, scientists have had to go much deeper, | :02:00. | :02:01. | |
to the level of DNA, to try and work out what happens | :02:02. | :02:04. | |
An international team of scientists, led by the Sanger Institute | :02:05. | :02:09. | |
in Cambridge, examined all 3 billion letters in the genetic code of every | :02:10. | :02:14. | |
What they've found has transformed the understanding of what happens | :02:15. | :02:21. | |
Getting a comprehensive collection of information, including the | :02:22. | :02:28. | |
mutations that are causing cancer, tells us something about why that | :02:29. | :02:32. | |
cancer is going wrong, why that cell is turning | :02:33. | :02:36. | |
into a cancerous cell, and if you can understand that, | :02:37. | :02:39. | |
you can understand the causes of the cancer, and then you can | :02:40. | :02:42. | |
This opens up the possibility of much greater individualised | :02:43. | :02:48. | |
treatments for cancer, targeting each of the mutations. | :02:49. | :02:51. | |
That's already happening with some treatments, like the drug | :02:52. | :02:55. | |
Herceptin, but experts believe this could be a big step forward. | :02:56. | :02:58. | |
What this study might achieve is finding | :02:59. | :03:00. | |
better treatments, matching them better to women. | :03:01. | :03:10. | |
By understanding the causes that underline the biology | :03:11. | :03:11. | |
of different types of the disease, we might be able to match better | :03:12. | :03:14. | |
treatments and offer them things that are more likely to work for | :03:15. | :03:17. | |
Back at home, Vanessa Babbage is moving on with her life after | :03:18. | :03:21. | |
cancer, and she is optimistic that science is starting to make real | :03:22. | :03:24. | |
headway in the fight against the disease. | :03:25. | :03:26. | |
It gives people hope, because when people are affected | :03:27. | :03:28. | |
by someone that they love and they have breast cancer, | :03:29. | :03:30. | |
they hope for a better future for other women that are going to be | :03:31. | :03:34. | |
This research has transformed the understanding of cancer, | :03:35. | :03:40. | |
and offers the tantalising prospect it could prevent the disease | :03:41. | :03:44. | |
In talks in Geneva to try to save the ceasefire in Syria, | :03:45. | :03:52. | |
the US Secretary of State John Kerry said foreign powers were "getting | :03:53. | :03:56. | |
There's been a two-month pause in hostilities in the country, | :03:57. | :04:01. | |
but the last ten days have seen an upsurge of violence. | :04:02. | :04:04. | |
Mr Kerry said a renewed ceasefire must include | :04:05. | :04:07. | |
the besieged city of Aleppo, where more than 250 civilians | :04:08. | :04:10. | |
Our correspondent Barbara Plett-Usher has been travelling | :04:11. | :04:16. | |
War has returned to Syria's largest city after two | :04:17. | :04:23. | |
The air strikes on a hospital last week thrust the carnage | :04:24. | :04:30. | |
back into the spotlight, but hundreds of civilians have | :04:31. | :04:33. | |
been killed in the past ten days of fighting. | :04:34. | :04:36. | |
The Syrian military says it is targeting jihadists, | :04:37. | :04:38. | |
But the lines between such groups and other rebels in Aleppo | :04:39. | :04:43. | |
If the cease-fire breaks down here, it may crumble across the country. | :04:44. | :04:52. | |
The crisis triggered emergency meetings in Geneva, | :04:53. | :04:54. | |
the city that's been hosting Syrian peace talks. | :04:55. | :04:56. | |
America's top diplomat came here to try to salvage the truce. | :04:57. | :05:01. | |
We are engaged in an effort with all of the members | :05:02. | :05:07. | |
of the international Syrian Support Group, | :05:08. | :05:11. | |
and with Russia particularly, in an effort to restore that | :05:12. | :05:17. | |
cessation of hostilities in those places where it has been most | :05:18. | :05:23. | |
There is no excuse for not finding, again, a reinvigorating | :05:24. | :05:31. | |
and reinstalling and re-implementing what has been the only strong | :05:32. | :05:36. | |
message the Syrian people have heard from all of us. | :05:37. | :05:39. | |
Mr Kerry is urging Moscow to push its Syrian ally to stop | :05:40. | :05:44. | |
But the most he announced he was a joint agreement agreement | :05:45. | :05:51. | |
to strengthen the monitoring and implementation of the truce. | :05:52. | :05:53. | |
So they are wrestling with a formula to bring quiet back to Aleppo. | :05:54. | :05:56. | |
Are there will be intensive talks involving the Russians | :05:57. | :05:59. | |
Mr Kerry said there should soon be greater clarity about the details of | :06:00. | :06:05. | |
But the bigger question is whether Damascus | :06:06. | :06:10. | |
and Moscow are serious about the UN path to peace, | :06:11. | :06:12. | |
or whether they are using it to make military gains on the ground. | :06:13. | :06:15. | |
Barbara Plett-Usher, BBC News, Geneva. | :06:16. | :06:19. | |
A 36-year-old man has been shot dead during an operation | :06:20. | :06:22. | |
Officers were called to a property near Maidstone last night, | :06:23. | :06:26. | |
The pre-planned operation was connected to the suspected | :06:27. | :06:31. | |
murder of Roy Blackman, who was beaten to death | :06:32. | :06:34. | |
during a burglary at his home last month. | :06:35. | :06:36. | |
The Independent Police Complaints Commission is now investigating. | :06:37. | :06:41. | |
A 21-year-old man has appeared in court accused of planning | :06:42. | :06:44. | |
The government is considering new laws on what happens | :06:45. | :06:46. | |
The proposals include plans for a customer code that would make | :06:47. | :06:50. | |
tipping more transparent and ensure that all tips do go | :06:51. | :06:52. | |
It follows major criticism of some restaurants for failing | :06:53. | :06:55. | |
to pass the money on, as our business correspondent, | :06:56. | :06:57. | |
Unlike some other national restaurant chains, | :06:58. | :07:03. | |
Gourmet Burger Kitchen doesn't apply an automatic service charge, | :07:04. | :07:07. | |
nor does it deduct any administration fees from tips. | :07:08. | :07:11. | |
If the Government has its way, that will be the norm. | :07:12. | :07:14. | |
I think it is only fair that if a customer leaves a tip | :07:15. | :07:17. | |
with the intention of it being given to the staff member, | :07:18. | :07:20. | |
Now, the Business Secretary, Sajid Javid, is proposing that | :07:21. | :07:23. | |
gratuities are passed on in full to service staff. | :07:24. | :07:26. | |
At the same time, he wants restaurants to make it much clearer | :07:27. | :07:29. | |
And he is proposing a new code, but says he will pass legislation | :07:30. | :07:35. | |
if companies continue to withhold tips from staff. | :07:36. | :07:38. | |
It's got to go to the people that you intend it to go to. | :07:39. | :07:42. | |
It also has to be voluntary for good service. | :07:43. | :07:46. | |
That is what everyone wants to see and that is why | :07:47. | :07:48. | |
But some critics say tipping has had its day. | :07:49. | :07:53. | |
I think it is time that we scrapped all forms of service charges | :07:54. | :07:57. | |
and tipping and simply increased waiters' salaries to make | :07:58. | :08:00. | |
The British public feel very uncomfortable when it comes | :08:01. | :08:04. | |
to tipping, they don't know where the money is going to. | :08:05. | :08:07. | |
It is also bizarre, in the 21st century, | :08:08. | :08:09. | |
that we have this weird servile relationship with waiters. | :08:10. | :08:12. | |
The general public are less sure about that. | :08:13. | :08:15. | |
I would like to think it is going to the waiters | :08:16. | :08:18. | |
and waitresses and the cooks and that it is shared | :08:19. | :08:20. | |
equally, but I'm not sure whether it is or not. | :08:21. | :08:23. | |
Everyone who gets tips, it just gets split at the end of the day. | :08:24. | :08:26. | |
I don't think that's fair because I might work | :08:27. | :08:28. | |
The restaurant business is very competitive and margins | :08:29. | :08:31. | |
But if restaurateurs are forced to hand over part or all | :08:32. | :08:36. | |
of the tips their staff get, it may drive some of them | :08:37. | :08:39. | |
Ultimately, it's the dining public who will decide whether and how much | :08:40. | :08:45. | |
An Australian computer scientist has ended years of speculation, | :08:46. | :08:54. | |
saying he is the creator of the controversial | :08:55. | :08:58. | |
Dr Craig Wright, who lives in London, | :08:59. | :09:03. | |
showed the BBC evidence that he launched the currency | :09:04. | :09:05. | |
Dr Wright is believed to hold hundreds of millions of dollars | :09:06. | :09:09. | |
of bitcoins, which are a virtual currency | :09:10. | :09:12. | |
transferred via the internet, and which can be exchanged | :09:13. | :09:14. | |
This exclusive report from our technology correspondent | :09:15. | :09:18. | |
In an office in London, a mystery that has been an intranet | :09:19. | :09:27. | |
obsession for seven years is about to be solved. | :09:28. | :09:29. | |
So you are going to show me that Satoshi Nakamoto is you? | :09:30. | :09:35. | |
If that is true then Dr Craig Wright is the reason there is a new | :09:36. | :09:42. | |
Bitcoin is a currency invented on the Internet and | :09:43. | :09:47. | |
designed to operate outside the control | :09:48. | :09:48. | |
Its value and its reputation has been | :09:49. | :09:53. | |
widely used by criminals has been the world spends. | :09:54. | :09:58. | |
It was back in 2008 that someone calling themselves Satoshi Nakamoto | :09:59. | :10:14. | |
published a paper on the Internet describing a plan for Bitcoins. It | :10:15. | :10:19. | |
was the following year that he introduced the software allowing the | :10:20. | :10:23. | |
currency to take shape. Ever since, Satoshi Nakamoto 's Mac precise | :10:24. | :10:27. | |
identity has been a mystery. Last year there was a speculation about | :10:28. | :10:33. | |
Craig White, a Dutch Craig Wright, an Australian scientist. Now he he | :10:34. | :10:36. | |
has confirmed that he is Satoshi Nakamoto. Some people will believe | :10:37. | :10:44. | |
and some people won't. I don't really care. The evidence published | :10:45. | :10:47. | |
by Dr Wright to prove that he is Satoshi Nakamoto 's been met with | :10:48. | :10:52. | |
some scepticism, but at a Bitcoin conference in New York today, a | :10:53. | :10:56. | |
leading figure said he was convinced. I met with him in London. | :10:57. | :11:01. | |
He fits the kind of person that I was interacting with back in 2010. | :11:02. | :11:08. | |
And he provided some cryptographic proof. It was a private key from the | :11:09. | :11:13. | |
very first Bitcoin. Craig Wright will not reveal how rich Bitcoin has | :11:14. | :11:17. | |
made him, that says he doesn't want to be a figurehead for the currency. | :11:18. | :11:22. | |
I don't want money, I don't want fame or adoration. I just want to be | :11:23. | :11:27. | |
left alone. I'm going to come in front of the camera once, and I will | :11:28. | :11:32. | |
never ever be on the camera ever again. If he is to be believed, he | :11:33. | :11:37. | |
is a modern day Midas, the man who conjured new money out of thin air. | :11:38. | :11:43. | |
It is a remarkable achievement, but having emerged from the shadows, | :11:44. | :11:47. | |
Craig Wright, or Satoshi Nakamoto wants to disappear once more. | :11:48. | :11:51. | |
This Thursday, voters across most of England and Wales will be able go | :11:52. | :11:54. | |
to the polls to elect their Police and Crime Commissioners. | :11:55. | :11:56. | |
PCCs were introduced in 2012, with the aim of making police forces | :11:57. | :11:59. | |
accountable and more responsive to public needs. | :12:00. | :12:01. | |
But voting then suggested widespread apathy for the new role. | :12:02. | :12:05. | |
Our home editor Mark Easton reports from the campaign trail | :12:06. | :12:07. | |
32 million people get the chance to vote for their Police and Crime | :12:08. | :12:13. | |
Commissioner in England and Wales on Thursday. | :12:14. | :12:15. | |
Here in Northamptonshire, three candidates are up for | :12:16. | :12:17. | |
I want to maintain front line policing. | :12:18. | :12:24. | |
The first thing I'll do is reduce the cost | :12:25. | :12:27. | |
of the office of Police and Crime Commissioner. | :12:28. | :12:29. | |
Local people should help decide where police resources | :12:30. | :12:34. | |
The idea behind PCCs is the elected commissioner would be | :12:35. | :12:37. | |
impartial, setting police priorities for all the people, whatever their | :12:38. | :12:41. | |
But there are concerns that candidates should | :12:42. | :12:49. | |
Of the 188 PCC candidates across England and | :12:50. | :12:52. | |
Turn-out last time was a miserable 15%, a little higher in | :12:53. | :13:05. | |
But hopes that the public would start to | :13:06. | :13:10. | |
embrace this new elected official with the power | :13:11. | :13:14. | |
to hire and fire the Chief Constable, well let's say this | :13:15. | :13:17. | |
election could be seen as a referendum on the PCC idea. | :13:18. | :13:21. | |
To be honest, I don't really know what's going on. | :13:22. | :13:32. | |
Do you think people are excited about it? | :13:33. | :13:34. | |
I don't think they are excited about it at all. | :13:35. | :13:37. | |
Their previous PCC, Tory Adam Simmonds, is standing | :13:38. | :13:44. | |
Praised by the Home Secretary for helping cut crime, he was | :13:45. | :13:48. | |
criticised locally for increasing his office budget while the police | :13:49. | :13:50. | |
I spent 30 years in business from a technology point | :13:51. | :14:01. | |
of view, so I want to see body-worn video | :14:02. | :14:04. | |
cameras, the latest technology - that will make the difference. | :14:05. | :14:07. | |
We have lost over 105 police officers in | :14:08. | :14:09. | |
Northamptonshire since 2010 and at the same time | :14:10. | :14:13. | |
crime has doubled over the past two years, so we need a better | :14:14. | :14:16. | |
We have seen over the years that the established political | :14:17. | :14:22. | |
parties have failed to address the problems of | :14:23. | :14:24. | |
Ukip is the party to change that, and so am I. | :14:25. | :14:30. | |
Turnout is likely to be higher this time than last | :14:31. | :14:34. | |
because in many places PCC elections coincide | :14:35. | :14:36. | |
But whatever the local situation, there seems there is | :14:37. | :14:41. | |
plenty of scope for increasing public enthusiasm. | :14:42. | :14:42. | |
Mark Easton, BBC News, Northamptonshire. | :14:43. | :14:47. | |
And finally, Leicester City didn't quite manage it yesterday, | :14:48. | :14:50. | |
but tonight there's another opportunity for them to clinch | :14:51. | :14:52. | |
If Spurs fail to beat Chelsea this evening, Leicester will | :14:53. | :14:56. | |
Andy Swiss is in Leicester, where fans are gathering | :14:57. | :15:00. | |
in pubs around the city to watch the match. | :15:01. | :15:09. | |
Yes, welcome to the local hero pub, just a stone's throw from | :15:10. | :15:16. | |
Leicester's Stadium. Among the fans who will be watching the TV rather | :15:17. | :15:21. | |
nervously tonight is lifelong Leicester supporter Lee job. Thank | :15:22. | :15:27. | |
you for joining us. If Tottenham don't win, Leicester are champions. | :15:28. | :15:32. | |
How confident are you that? It's got to happen tonight, surely. If you'd | :15:33. | :15:36. | |
asked me two days ago, I would have wanted it to happen at Old Trafford | :15:37. | :15:41. | |
yesterday. Let's just get it on and enjoy the rest of the week, and | :15:42. | :15:46. | |
party on to next week. I don't want to go to Chelsea needing points. | :15:47. | :15:50. | |
Let's get it out the way and enjoy Champions League. No one has | :15:51. | :15:53. | |
mentioned that because everyone is so wrapped up in the potential title | :15:54. | :15:59. | |
win. What a story, the Champions League, the whole Leicester story | :16:00. | :16:04. | |
itself... The whole city is either anxious or buzzing. Everyone has | :16:05. | :16:07. | |
different feelings about the situation. Let's get it out the way, | :16:08. | :16:16. | |
take it to Everton and a massive party at the weekend. What would it | :16:17. | :16:19. | |
mean to you to see your beloved Leicester be crowned champions? I | :16:20. | :16:21. | |
don't know if there is a word for it. It needs to be added to the | :16:22. | :16:26. | |
dictionary! I know it is positive, and a million times better than | :16:27. | :16:31. | |
great. It should be a nervous nights a Leicester fans, but could be a | :16:32. | :16:34. | |
very special one. | :16:35. | :16:37. |