Extinction Dara O Briain's Science Club


Extinction

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Transcript


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Let me tell you about the most unlucky animal in the world.

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It's called the Pyrenean ibex.

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Due to over-hunting in 1973 it got put on the endangered species list.

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But the last one didn't die until the year 2000,

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when a tree fell on it.

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But luckily they'd extracted some DNA and they were able to clone it.

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And then the clone died.

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The Pyrenean ibex is the only animal in history

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that's gone extinct twice.

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Tonight we're talking about extinction.

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I'm Dara O Briain, welcome to Science Club.

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APPLAUSE

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Good evening, everyone. Great to have you here.

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This is the show that takes apart all kinds of subjects

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and looks at them from many different angles.

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To help us do that we've got our curious sciencey audience

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and some fantastic guests.

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Palaeontologist, Richard Fortey,

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zoologist, Lucy Cooke,

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our resident supporters Dr Helen Czerski and Dr Tali Sharot,

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science supporter, Alok Jha,

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and special guest, Mark Steel. How are you, Mark? Are you well?

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-Very well.

-Lovely to have you here.

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Of course, we also have Professor Mark Miodownik

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who'll be conducting some exciting experiments, ladies and gentlemen,

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featuring, as ever, strong Eastern European vodka.

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Tonight on the show we'll be looking at extinction

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and asking how species come and go from our planet,

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what we should do about it,

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and if indeed we should do something about it at all.

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But don't be depressed,

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it won't all be tearful goodbyes and guilt trips for humanity.

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This being Science Club,

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Dr Tali Sharot explores the ultimate fast food

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and visits the first-ever taste test of man-made beef.

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Are you anxious?

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Oh yes, I am, definitely.

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Comedian Mark Steel attempts to save the planet and goes on a quest

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to find out how we should deal with any incoming asteroid.

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One that has been discovered is a thing called Apophis.

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Great names, by the way.

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Is it people who were put out of work when Star Trek was finished?

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And science journalist Alok Jha asks the unaskable,

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should we just let the pandas die out?

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For extra info while the show is on, you can follow us on Twitter

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or visit the website.

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Details at the bottom of your screen.

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CHEERING AND APPLAUSE

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Right, tonight we have the pleasure of two esteemed science gurus on our sofa,

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palaeontologist, fellow of the Royal Society,

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doyen of the Natural History Museum in London, Richard Fortey,

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and zoologist, TV presenter and amphibian expert, Lucy Cooke.

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APPLAUSE

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How are you, Richard, Lucy? Pleasure to have you both here.

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Welcome to Science Club.

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We don't normally expect people to arrive in with

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a show-and-tell type gift, what have you brought us in?

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I've brought you in a trilobite.

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A proper...how old?

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This is a 400 million-year-old animal,

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and if we're talking about extinction, these are extinct.

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But they had a good innings. How long were they around?

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They were around for 250 million years,

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that's a great deal longer than we've been around.

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Lucy, speaking of presents,

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at the moment you are dealing with amphibians, frogs, predominantly.

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I love frogs, yes.

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LAUGHTER

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Why is that funny?!

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Frogs just are funny.

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I don't see why it is funny. I think they are amazing creatures,

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and I think they should get more attention.

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-Yay, frogs.

-Yay frogs, exactly, that's what I'll be doing all through the show,

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repeatedly, until you all agree with me.

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Tell me about this thing.

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We tend to presume this is a model of extinction,

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which is the dodo, the mortal enemy of the Portuguese sailor.

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But this is a perfectly natural process,

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it's not just us dabbling or asteroids crashing,

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it is what has been going on on this planet.

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That's a very important point. Extinction is a natural process.

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It happens at a regular, slow pace.

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If it didn't, we wouldn't be here.

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We're going to cover a number of these things,

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including what kind of catastrophes there are,

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the manner in which man-made disasters can occur.

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Just a quick historical view.

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It is only relatively recently that we've actually understood the idea of extinction at all.

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Even a couple of hundred years ago

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we had no idea that species emerged and disappeared.

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So let's have a look at how previous generations have thought about species loss.

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Although the dodo is THE poster boy of extinction,

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it took 100 years before anyone realised

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that the dodo had in fact gone extinct.

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Extinction as a concept made no sense to anyone. The reasons are twofold.

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First, it didn't make sense that

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God would let all his hard work go to waste and let creatures die out,

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and second, nobody imagined the earth was very old.

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In the 1650s an Irish bishop, James Ussher,

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looked at who begat whom in the Bible.

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Using this he announced that the earth was less than 6,000 years old.

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Even more precisely, it was created on Sunday, 23 October, 4004 BC,

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even though, technically, Sunday should have been his day off.

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The first clue maybe this was a tiny bit out came from fossils.

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For years people thought fossils had simply fallen from the sky,

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or were left by the devil.

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By the end of the 1700s

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fossils had become something of an elephant in the room.

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Quite literally when French naturalist Georges Cuvier

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presented a paper on fossilised elephant bones in the 1790s.

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He made the controversial claim that one was the jaw of a creature

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that no longer existed, an animal that was extinct.

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It turned out to be a mammoth.

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While many scientists argued that the animals were still around,

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just they hadn't been found alive yet,

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but Cuvier was adamant

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suggesting this and other extinctions were caused by catastrophic events.

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By the early 19th century, although extinction had been established,

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the Bible still held sway.

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And Noah's Flood

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was deemed responsible for both extinction and fossils.

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But again, the earth suggested otherwise.

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A Scottish physician, James Hutton,

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developed the concept of deep time and geology.

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Now, using the power of geology, the estimated age of the earth

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spread from thousands to millions,

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and finally, thanks to the advent of radioactive dating,

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we now know that the earth is about 4.5 billion years old.

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Then, towards the end of the 20th century,

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as geologists looked more closely,

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periods of mass extinction were identified,

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times when species were dying out at quite frankly an alarming rate.

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It was one of these, however, that gave mammals their big break,

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and consigned dinosaurs

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to the entrance halls of natural history museums.

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Ultimately, this paved the way for we humans

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to become the dominant animal on earth.

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In the course of our ascendency,

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we have been responsible for quite a few extinctions ourselves.

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Of course, there is the dodo,

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but there is also the Steller's sea cow,

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extinct within a mere 27 years of its discovery.

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And the Tasmanian wolf, listed as an endangered species

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three years after the last one was seen in the wild.

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Indeed, we are so good at killing animals

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it's been suggested we're actually in the middle of

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a great period of extinction right now.

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All of our own making.

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APPLAUSE

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So...

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if the number of animal species dying out could be graphed,

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it would be a steady level of noise but with spikes for massive events.

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What kind of events are we talking?

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Well, the great dying was about 250 million years ago,

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at the end of the so-called Permian Period,

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where 90%...90% of all species are supposed to have died out.

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That's the biggest one in the history of life that we know.

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The ones where dinosaurs died out, the K-T Event,

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the figure's about 60% there,

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so it is very, very serious

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and a lot of people think we are now in a man-made one,

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just at the moment.

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99.9% of all species that have ever lived on the planet are now gone.

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Yes.

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The thing about extinction is it is a natural process,

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but it is happening at an unnatural rate at the moment.

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For instance, the amphibians,

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my best friends, they are one of the most threatened class of animals

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and their rate of extinction is something like 25,000 to 45,000 times the normal base rate.

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There is the passenger pigeon, the passenger pigeon was hunted

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because they use to flock in mass,

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there was a point at which you could shoot them,

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you could shoot 50 in one go.

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The sky was dark with them.

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Yes, people thought you couldn't over-hunt them.

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And there was a small 14-year-old boy in Ohio who killed the last one.

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It takes a fair amount of guts to be the last person to go,

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this is the one, photograph with the very last one.

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The sad thing is, something you can eat, for example,

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the fewer there are, the more the price goes up,

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the supplies of some of the rarer species of tuna,

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so the more the hunters go after them.

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Many factors cause extinction

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and the last couple of hundred years we've added some of our own.

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In honour of the passenger pigeon and the dodo,

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which was also a type of pigeon, by the way,

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Prof Mark Miodownik presents a guide to the humble shotgun.

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Technology turned the human hunter into a killing machine.

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The shotgun is the perfect piece of kit

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to solve the problem

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of how to get a bird from the sky onto your dinner plate.

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But with a shotgun, you can kill more than you could ever eat.

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It may seem obvious,

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but what's so special about the shotgun is the shot.

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So unlike other guns which fire one bullet at a time,

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shotguns fire many little projectiles.

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Let me show you what it looks like

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if you fire a shotgun at a target from about 40 yards.

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You can see all these tiny little impacts.

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That makes it ideal for trying to hunt or shoot fast-moving objects,

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because you don't have to be entirely accurate to hit something.

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As long as you hit something in here you are very likely to kill it.

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Shot means that even unskilled hunters

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can bring down huge flocks of birds, all too easily.

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This is a flintlock shotgun.

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It consists of three parts, a lock, a stock and a barrel.

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In this type of shotgun

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the shot goes down the barrel here,

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but before it goes down we need to add a propellant

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and that's gunpowder.

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Saltpetre, sulphur and charcoal.

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And then we just need to add the final ingredient, fire.

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Mind out.

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The Chinese invented gunpowder and they used it for fireworks,

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and you can see why.

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But what you can't see is

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the huge amount of carbon dioxide that is given off,

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and it's that that's useful for guns.

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The carbon dioxide creates a huge pressure inside the barrel,

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which propels the shot out.

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But muzzle-loading guns are slow to reload.

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However, one simple invention

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drastically improved the rate of firing,

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and turned the shotgun into something that can kill on an industrial scale.

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The cartridge encapsulates all the stages of loading a gun,

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in one container.

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It makes it easier, quicker and more reliable.

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It has the top cap, the shot,

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the wad, the gunpowder, the cartridge,

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and one extra ingredient,

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the primer.

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And this contains a pressure-sensitive chemical

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that explodes on impact.

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The cartridge meant that the design of the shotgun's lock mechanism,

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which is activated when you pull the trigger, had to change.

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Here is the side lock. This is the mainspring.

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When the trigger is pulled

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it throws the hammer forward

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and that hammer

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impacts the firing pin here.

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And that pushes through and detonates the cartridge.

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Then the rest follows, the gunpowder ignites,

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the carbon dioxide is produced,

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pressure builds up,

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the shot is propelled out,

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and that all happens in a split second.

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The dramatic increase in the speed of reloading

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meant that within 50 years of the invention of the shotgun cartridge

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the passenger pigeon,

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once one of the most numerous birds on the planet,

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was wiped out completely.

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APPLAUSE

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But extinction...extinction isn't necessarily

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always as obvious as shotguns and changed habitats.

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-It moves in mysterious ways, sometimes.

-Very mysterious.

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Who are these?

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This is Xenopus, the African clawed toad.

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He is very likely responsible

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for one of the biggest extinction crises

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since the dinosaurs were wiped of the planet.

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And that's happening right now.

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It's happening right now.

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His fellow amphibians are being wiped out in massive numbers.

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How massive? Compare it to the dinosaurs being wiped out,

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how many frogs, species of frogs?

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There's 40% hurtling towards extinction.

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It's more than any other vertebrate.

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And there's about... over 120 that have gone extinct in the last 20-odd years.

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Why is this frog at fault and why is this frog not extinct?

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Well, so this amphibian here

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is the sort of Typhoid Mary of the amphibian extinction.

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And asymptomatic carrier of something.

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So amphibians are being killed off globally by fungus,

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the question was, where is this coming from?

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They have figured out the likely suspect is this frog.

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It carries this particular fungus and spreads it.

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This is the frog which is very popular in the scientific community.

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It's your standard default frog for experiments.

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Exactly, he is a scientific superstar,

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the first vertebrate to be cloned and he's even been into space.

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Wow, hell of a frog!

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There is actually very funny footage, the frog doing that.

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Can we get it out? Is it likely to get out?

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Yes, he's a very slippery customer, I'm going to try to get him out.

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This is an African clawed toad, and he evolved and lived in Africa

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until a chap called Lancelot Hogben,

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who was studying the effects of hormones on amphibians,

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was also working in South Africa,

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and he stumbled upon this frog and started using it in his experiments.

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What he discovered was that this frog makes a great pregnancy test.

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This is not... When are we talking about, 1920s?

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This frog was the number one pregnancy test in the world.

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For almost 20 years.

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If you go into family planning clinics in London,

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they'd have a basement full of frogs who would be

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consulted as to whether you were pregnant or not.

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Just to confirm, it did not mean you needed to wee on the frog.

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If you wee on it, it does not turn blue. That's not how it works.

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What did you have to do?

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You inject its lymph gland with a woman's urine,

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and if she's pregnant, the frog will lay eggs within 8 to 10 hours.

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It got exported out of Africa into labs all over the world

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so that lots of ladies could find out if they were pregnant.

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It's a young, healthy, virile crowd in the peak

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of their reproductive years, does anyone who's not sure if they may

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be pregnant... No judgements will be passed, we're not that kind of show.

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This is merely science. Nobody is stepping forward.

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It's really unfair that you're not taking part in this experiment.

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Is this very common?

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Basically, what happened was it got exported to laboratories

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all over the world, and when the little blue strip replaced the toad,

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people were like, "What are we going to do with all these toads?"

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They just released them.

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What they didn't know was that it carries a fungus on its skin.

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Is it just a case of plunging your hand in?

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Yes, plunge your hand in, they are slippery,

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so try to catch them in a scoop.

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Am I in danger of breaking them? Thank you very much.

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APPLAUSE

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No, no. Really patronising round of applause,

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given I hadn't actually caught the frog.

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Stop, stop. You're there. You're a bad frog. You're a bad, evil frog.

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I'm going to drop you from a great height and it'll teach you a lesson.

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His little face! Look at that. Oh no!

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-Hang on, they're very slippery.

-That's fine, nobody saw that.

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APPLAUSE

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OK.

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There are many factors that influence extinction,

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one of the key reasons for current extinction is us,

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our meat-eating habits, we like steaks.

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But they devastate other animals' habitats. Let's look at the numbers.

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Lots of land is taken up with producing meat.

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Each person in the United States consumes

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an average of 120 kilograms a year, that's 1,060 quarter pounders.

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Brits get by on 84.2 kilograms.

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Since 1961, the UK has increased its total meat consumption by a fifth,

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to 84.2 kilograms per person.

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America by a third, and China is now eating 15 times as much.

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To feed these mouths,

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America's meat production has more than doubled in less than 50 years.

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India's has more than tripled,

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and China in the same period has increased production by 30 times.

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There are now at least 1.4 billion cows on planet Earth

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with a total mass of 550 million tonnes.

0:18:270:18:31

If you put them on a scale with every wild mammal,

0:18:310:18:34

cows would outweigh them 10 to 1.

0:18:340:18:36

APPLAUSE

0:18:360:18:39

Yes, yes.

0:18:390:18:40

We are obviously applauding the making of that film rather

0:18:410:18:44

than the sentiments involved, because we just love burgers.

0:18:440:18:49

-It's not just burgers, either.

-It's frogs' legs as well.

-Really?

0:18:490:18:53

You think of the French eating frogs' legs,

0:18:530:18:55

but actually there is a billion frogs imported into America every year.

0:18:550:18:59

-There is no eating in the middle part of a frog.

-I've never tried it.

0:18:590:19:03

I'm just saying, clearly there is a billion frog middles waiting

0:19:030:19:08

to be eaten at the moment.

0:19:080:19:10

Yes, we are diluting the planet in the search of making burgers,

0:19:100:19:14

but just in time, science comes riding into the rescue.

0:19:140:19:17

Do you want to see the future of food?

0:19:170:19:19

In a Science Club exclusive, Tali Sharot

0:19:190:19:21

has been to Maastricht in Holland to bear witness to a historic event.

0:19:210:19:26

This Petri dish could provide a solution to reducing

0:19:320:19:35

the impact we are having on species extinction.

0:19:350:19:38

These are bovine muscle cells.

0:19:380:19:41

They will be turned into a piece of beef steak,

0:19:410:19:43

but one that has been grown in the lab.

0:19:430:19:46

At the University of Maastricht, for the last five years

0:19:490:19:53

Professor Mark Post has been perfecting a way to create lab-cultured meat.

0:19:530:19:57

The idea is very old, in 1932,

0:20:000:20:04

Winston Churchill put forward this idea that you could grow pieces

0:20:040:20:09

of meat without the entire animal, because it seemed inefficient

0:20:090:20:12

to grow an entire animal if you're only eating the wings or the legs.

0:20:120:20:17

The process begins by taking a biopsy of muscle from a cow.

0:20:190:20:23

From this bovine muscle, stem cells are isolated.

0:20:230:20:27

These are the undifferentiated cells that go on to grow into muscle fibres.

0:20:270:20:32

These individual stem cells are then suspended in Petri dishes

0:20:350:20:38

and nutrients and placed in an incubator to grow.

0:20:380:20:42

At the moment,

0:20:420:20:44

there's not enough meat here to make even one single dinner, it is

0:20:440:20:47

running at a very small scale, more proof of concept.

0:20:470:20:51

But it's thought that when the process is scaled up,

0:20:510:20:54

cells from one single biopsy of muscle, from one single cow,

0:20:540:20:58

would be able to produce over 20,000 tonnes of lab-grown beef.

0:20:580:21:04

As they multiply, the muscle cells naturally fuse together to form fibres,

0:21:060:21:09

which are then encouraged to form these rings of muscle tissue.

0:21:090:21:14

After about six weeks, the rings of muscles are harvested

0:21:190:21:22

and cut into strips.

0:21:220:21:24

They might not look like traditional muscle tissue,

0:21:240:21:27

because there is no blood or fat or connected fibres,

0:21:270:21:31

but at the cellular level,

0:21:310:21:32

each strip is indistinguishable from regular beef.

0:21:320:21:37

It's one thing to grow muscle cells in the lab,

0:21:400:21:43

but at the moment this looks like tiny little worms.

0:21:430:21:46

It doesn't smell very appetising either.

0:21:460:21:49

Really, the key in passing man-made meat as a nice piece of beef

0:21:490:21:53

lies wholly in the taste.

0:21:530:21:55

-Have you tasted your lab-grown beef yet?

-We haven't yet.

0:21:570:22:00

We're going to do that this afternoon.

0:22:000:22:02

I'm very excited about that.

0:22:020:22:04

This is actually the first time we have sufficient material

0:22:040:22:07

to make tasting a realistic thing to do.

0:22:070:22:11

To oversee this historic moment,

0:22:140:22:16

Mark has drafted in food technician Peter.

0:22:160:22:19

Looks a bit like noodles.

0:22:300:22:32

I agree, yeah.

0:22:320:22:34

'Peter's first task is to try to turn these strips of man-made meat

0:22:360:22:39

'into something like a miniature hamburger.'

0:22:390:22:42

-How many individual fibres do we have there?

-Around 600.

0:22:430:22:47

And they are all individually grown.

0:22:480:22:51

'The muscle fibres are mixed with salt to bind them together,

0:22:520:22:56

'then, it's into the frying pan.'

0:22:560:22:58

-Are you anxious?

-Yes, I am, definitely.

-Very much so.

0:23:000:23:05

-OK, the first-ever frying of lab-grown meat.

-Yes.

0:23:070:23:10

'It doesn't look like much, but this is a big moment in culinary science.

0:23:110:23:17

'Peter assesses if the tiny burger is behaving like a more traditional beef patty.'

0:23:170:23:21

A little bit of shrinkage.

0:23:220:23:23

-The water is coming out.

-Yes, which is normal. It was quite wet.

0:23:250:23:30

-That's to be expected.

-How does it smell?

0:23:300:23:33

-Neutral.

-Neutral.

-Yeah.

0:23:360:23:39

There you see a slight, brown, crispy brown coating appearing.

0:23:390:23:46

'Finally, the moment of truth.

0:23:470:23:50

'It may be one very small mouthful,

0:23:500:23:53

'but it's one giant leap for the future of lab-grown beef.'

0:23:530:23:57

-Go ahead.

-Really? Well, here we go.

0:24:010:24:04

I don't need a big fork like this.

0:24:040:24:06

It's salty.

0:24:130:24:15

It has a very smooth texture.

0:24:160:24:19

You feel the individual fibres, still.

0:24:230:24:26

And it basically tastes like fried chicken.

0:24:260:24:31

It is fried chicken. Salty, fried chicken.

0:24:310:24:34

So in its most naked of forms, even beef tastes like chicken.

0:24:350:24:39

It's going to take around 3,000 strips of lab-grown muscle fibres

0:24:410:24:45

just to make one average-sized hamburger.

0:24:450:24:48

But Mark has already started cultivation.

0:24:490:24:52

Admittedly, I was a little bit sceptical this morning,

0:24:520:24:56

but after seeing it cooked now, I'm much more convinced.

0:24:560:24:59

Although I wasn't allowed to taste the actual meat, it did smell

0:24:590:25:04

and look like proper meat.

0:25:040:25:06

Maybe in the future, we're all going to make burgers from this lab-grown beef.

0:25:060:25:10

APPLAUSE

0:25:100:25:13

You could go either way, you could mock them for the ridiculousness

0:25:160:25:21

of making a tiny white hamburger, and poring over it,

0:25:210:25:23

or you could say that was history being made to a certain extent.

0:25:230:25:27

Do you think it was history?

0:25:270:25:28

Yes, it took them 15 years to get there,

0:25:280:25:32

so it's a lot of work just making that tiny little piece of beef,

0:25:320:25:36

but as we said, it's a proof of concept.

0:25:360:25:40

Are there any vegetarians in the room?

0:25:400:25:42

As a vegetarian, are you vegan?

0:25:420:25:46

I'm vegetarian, and I think I would eat fake meat like that.

0:25:460:25:49

It would be quite interesting to try.

0:25:490:25:51

You could put yourself aside...

0:25:510:25:53

It wouldn't be a grey area, the fact that it is taken from stem cells?

0:25:530:25:56

I'd have to try it and think about how I felt about it after trying it.

0:25:560:26:00

I'm loving the journey.

0:26:000:26:02

"I'd think about how I felt, aw, I like the cow."

0:26:020:26:07

Is there anyone who just wouldn't take it at all,

0:26:070:26:11

who finds the idea of it quite disgusting? Anyone with that objection to it?

0:26:110:26:14

That's quite interesting, nobody thought that small, white...

0:26:140:26:19

No disgust kicked in.

0:26:190:26:21

The other thing, our fear about beef is the amount of resources it takes

0:26:210:26:25

to create a single hamburger.

0:26:250:26:27

It's an insane amount of effort. Grain and water...

0:26:270:26:31

That doesn't look like it's particularly efficient.

0:26:310:26:35

At the moment it isn't.

0:26:350:26:36

At the moment they have vast resources that you have to put in

0:26:360:26:40

to make that tiny little piece.

0:26:400:26:42

It's not helpful at the moment.

0:26:420:26:44

It's a good avenue to try, at this point I don't think we know...

0:26:440:26:49

-OK.

-..if it will be something that will be fruitful.

0:26:490:26:52

The goal is that sometime in the future,

0:26:520:26:56

you can take one biopsy from one cow, and make hundreds of burgers.

0:26:560:27:01

Presumably if we can do it for cows, we can do it for pigs, we can do it for chickens.

0:27:010:27:05

If we can make a chicken taste more like chicken...

0:27:050:27:08

-A chicken that tastes like fish, maybe.

-That would be fantastic.

0:27:080:27:11

OK, we have a lot in tonight's show, as ever.

0:27:110:27:14

If you'd like to know more, there are a number of ways you can get involved.

0:27:140:27:17

You can go to the website, you can follow us on Twitter,

0:27:170:27:22

for extra science like surprising facts and helpful doodles,

0:27:220:27:26

and you can join the conversation at hashtag scienceclub.

0:27:260:27:30

Still to come, Dr Helen Czerski goes in search of the secrets

0:27:310:27:34

of resurrection, visiting a lab in New Orleans in the US

0:27:340:27:38

where they're working on bringing extinct species back to life.

0:27:380:27:42

Comedian Mark Steel attempts to save the planet and goes on a quest

0:27:420:27:47

to find out how we should deal with any incoming asteroids.

0:27:470:27:50

There is now a whole industry working on trying to save

0:27:500:27:53

species around the world, but isn't it all being done in a piecemeal way?

0:27:530:27:58

Are we putting our efforts into the right animals?

0:27:580:28:01

Science journalist Alok Jha dares to ask the question,

0:28:010:28:04

should we just let the pandas die?

0:28:040:28:07

Humans have increased the level to which things are going extinct.

0:28:090:28:12

We've increased the speed.

0:28:120:28:14

So some of us might think that we've got a responsibility

0:28:140:28:18

to try and save as much as possible.

0:28:180:28:20

But we don't have infinite resources, so in that finite world,

0:28:200:28:24

what do we choose to save?

0:28:240:28:26

I think the world would be a far worse-off place

0:28:560:28:58

if it didn't have giant pandas.

0:28:580:29:01

This is a species that has been on the planet in one shape or form

0:29:010:29:04

for about 8 million years.

0:29:040:29:06

That means it's been on the planet a lot longer than we have.

0:29:060:29:10

Habitat loss is the greatest man-made threat to wild pandas,

0:29:100:29:15

yet it's a habitat they don't seem entirely suited to.

0:29:150:29:19

They evolved as carnivores, yet gave up meat in favour of just bamboo.

0:29:190:29:24

They also have a very dull sex life.

0:29:250:29:28

These animals are a bit weird, they don't really help themselves.

0:29:300:29:33

They're only on heat for three days a year,

0:29:330:29:35

and they are really fussy eaters.

0:29:350:29:37

So you have to really ask yourself the conservation question,

0:29:370:29:42

are they cost-effective? Basically, are pandas worth the effort?

0:29:420:29:47

At the Zoological Society of London, they are running a project

0:29:530:29:57

that is helping decide how limited conservation funds are best spent.

0:29:570:30:00

So, what they are trying to do here is find the most important species,

0:30:020:30:06

work out how important they are to their environments,

0:30:060:30:09

and then prioritise their conservation.

0:30:090:30:12

They are looking for evolutionarily distinct

0:30:160:30:18

and globally endangered species, or EDGE for short.

0:30:180:30:22

They hope that by giving EDGE species priority,

0:30:220:30:27

they can maintain as wide a gene pool as possible.

0:30:270:30:30

So, how do you go about selecting the animals for that programme?

0:30:330:30:37

They are not always the most pretty. They are the weird and wonderful,

0:30:370:30:40

the things that have really kind of developed on their own, in their

0:30:400:30:43

own lineage, that are really special, be that genetically

0:30:430:30:46

or the type of body shape they have, the type of things they do in the wild.

0:30:460:30:51

In terms of genetics and evolution, they are really important

0:30:510:30:54

-and interesting and different?

-Yeah, that's right.

0:30:540:30:57

If I was going to force you to choose, EDGE species or pandas...

0:30:570:31:02

-Which would I choose?

-What are you going to choose?

0:31:020:31:04

I would choose the EDGE every day.

0:31:040:31:06

If we were to lose the EDGE species, we would be losing species which

0:31:060:31:10

provide key functions within those environments,

0:31:100:31:12

things that really engineer the ecosystems they live in.

0:31:120:31:17

Alongside the pure science value,

0:31:180:31:21

you can also factor in the value that species bring directly to us.

0:31:210:31:26

Like the many varieties of bees and other pollinating insects.

0:31:260:31:29

-So, Dave, what have bees ever done for us?

-Bees have done lots for us.

0:31:340:31:39

As we can see here, they pollinate our crops.

0:31:390:31:43

Roughly a third of the food we eat is insect pollinated.

0:31:430:31:47

That third includes most of the really interesting,

0:31:470:31:49

nice, tasty stuff - raspberries, blueberries, runner beans,

0:31:490:31:53

courgettes and so on.

0:31:530:31:55

Without the insect pollinators, no fruit or veg.

0:31:550:31:58

Sadly, due to increased pesticide use and loss of habitat,

0:31:590:32:03

many bees species are now in decline across the globe.

0:32:030:32:06

But compared to other wildlife,

0:32:080:32:10

losing bees would have much more far reaching effects.

0:32:100:32:13

If we lose our bees, we're going to lose our wildflowers, which means

0:32:150:32:19

that entire ecological communities would collapse and all the other

0:32:190:32:22

species that are dependent on those flowers will also disappear.

0:32:220:32:26

So it is not just bad for our diets if we lose bees,

0:32:260:32:30

we are talking about a kind of ecological armageddon.

0:32:300:32:33

Does it bother you that millions and millions of pounds are spent

0:32:330:32:36

on other charismatic mega-fauna, pandas, for example?

0:32:360:32:40

Everyone likes pandas. They are big and cute and furry.

0:32:400:32:43

But actually, ecologically, those creatures are nowhere near

0:32:430:32:47

as important as the little furry things

0:32:470:32:49

flying around our heads at the moment.

0:32:490:32:51

So, are the panda's days numbered? Maybe.

0:32:540:32:59

But it is possible that this is a species

0:32:590:33:01

that transcends pure scientific reasoning.

0:33:010:33:04

Perhaps being a conservation pin-up is enough.

0:33:040:33:06

The animals are here to help us

0:33:100:33:13

highlight the issues of giant pandas in the wild, through our visitors.

0:33:130:33:18

They are there to help us generate cash for ourselves,

0:33:180:33:22

which we then reinvest back into conservation research and education.

0:33:220:33:26

So it is self-sustaining.

0:33:260:33:27

APPLAUSE

0:33:340:33:37

Alok, look into the giant, doey eyes of the panda and tell me

0:33:370:33:41

you would let the pandas die.

0:33:410:33:43

I'm not suggesting we take a shotgun and shoot all these things in the wild.

0:33:430:33:47

They are not helping themselves.

0:33:470:33:49

Why don't we just take a sense of perspective?

0:33:490:33:51

The hundreds and hundreds

0:33:510:33:52

of millions of pounds we spend on this animal,

0:33:520:33:54

as cute as it is, honestly,

0:33:540:33:55

really cute, I saw one up close, we could spend them

0:33:550:33:59

on so many other things, great apes, for example,

0:33:590:34:01

they are also endangered.

0:34:010:34:03

Orang-utans and gorillas, a few thousand left.

0:34:030:34:06

Why not just shift some of that money into those things?

0:34:060:34:09

Are we running at a net loss on pandas?

0:34:090:34:12

Do they not bring so many people into a zoo...?

0:34:120:34:14

The zoo says, we bring these people in, it gives us visitor numbers,

0:34:140:34:17

we get money and then put that into other conservation programmes.

0:34:170:34:21

I am not sure I believe that actually works,

0:34:210:34:24

because they will spend £20 million over the course of a decade

0:34:240:34:28

on looking after these pandas

0:34:280:34:29

because of the amount they eat, the stuff they are housed in,

0:34:290:34:31

I am not sure they will get

0:34:310:34:33

£20 million worth of visitors in that time.

0:34:330:34:35

Not to get bogged down in the numbers, but we do rent pandas.

0:34:350:34:38

Anyone who has a panda outside China is paying a yearly lease to China.

0:34:380:34:42

£1 million a year per panda.

0:34:420:34:44

And it costs about several hundred thousand pounds

0:34:440:34:47

a year for maintenance, and every panda baby that is born,

0:34:470:34:49

and they will try and have babies, belongs to China immediately.

0:34:490:34:52

Richard, how do you feel on this?

0:34:520:34:54

Well, you know, who can resist a panda?

0:34:540:34:57

But I do think the important thing is,

0:34:570:35:00

if you conserve a species, it is too focused.

0:35:000:35:05

What you need to do is conserve the species which also conserves

0:35:050:35:08

the whole habitat in which it lives.

0:35:080:35:10

So I am not saying don't save the panda, but rather,

0:35:100:35:15

if you save the panda, save the whole environment in which it lives.

0:35:150:35:19

We all know that tremendous environmental degradation

0:35:190:35:22

is going on in China right now.

0:35:220:35:23

And if we can save a flagship species

0:35:230:35:27

and a whole habitat as a result, that has to be a good thing.

0:35:270:35:30

Lucy, what kind of monster would prioritise away from the panda?

0:35:300:35:36

-Where are you on this?

-I say, stuff the panda, save the salamander!

0:35:360:35:39

-Really?

-Yeah.

0:35:390:35:41

APPLAUSE

0:35:410:35:44

Why... Firstly, why the salamander?

0:35:440:35:46

Because the giant Chinese salamander

0:35:460:35:49

shares a mountain home with the panda,

0:35:490:35:51

and the albino version in particular may look

0:35:510:35:55

like a six-foot penis and be slightly less cute and cuddly,

0:35:550:35:59

but it is the world's largest amphibian,

0:35:590:36:02

it is an incredible creature, it has been around for millennia.

0:36:020:36:05

And it gets almost no conservation funding.

0:36:050:36:07

In fact, there was a study about three years ago that showed

0:36:070:36:10

the charismatic mega-fauna get 500 times more funding

0:36:100:36:14

for conservation and research than, say, endangered amphibians.

0:36:140:36:18

Can I just throw it to the audience, just a show of hands?

0:36:180:36:21

I want to put this in a way

0:36:210:36:22

which doesn't lead the questions too much.

0:36:220:36:24

But would you let the pandas die... That's emotive, isn't it?

0:36:240:36:28

Do you think we place too much emphasis on pandas, let's say,

0:36:280:36:33

and that kind of enormously charismatic...

0:36:330:36:36

Mega-fauna is the word of the day, I believe!

0:36:360:36:39

How many of you would let the pandas die in this situation?

0:36:390:36:43

-The majority...

-Not bad!

-The majority,

0:36:430:36:46

when the argument is made a certain way, can see other priorities.

0:36:460:36:50

If tonight's programme has given you

0:36:500:36:51

some burning questions about extinction,

0:36:510:36:53

we have our after-hours science club starting when we finish,

0:36:530:36:56

when an extinction expert is waiting to answer your questions.

0:36:560:36:59

Just go to the website to please get involved.

0:36:590:37:01

Let's assuage our species guilt here.

0:37:050:37:07

It's not all about the damage we are doing.

0:37:070:37:09

We ourselves could be the victims of extinction.

0:37:090:37:12

I mean, we have had major events occur.

0:37:120:37:14

How many major extinctions do we now think there have been?

0:37:140:37:18

Everybody is agreed on five.

0:37:180:37:21

And the one we are doing now is sometimes

0:37:210:37:23

-regarded as the sixth extinction.

-The one previous to that,

0:37:230:37:26

-was that the dinosaurs one?

-The big KT event, yes.

-But even now,

0:37:260:37:30

it's one of these things we've always known,

0:37:300:37:32

that asteroids killed the dinosaurs, that's relatively recent, isn't it?

0:37:320:37:36

Yes, the evidence for the arrival of the meteorite was gleaned

0:37:360:37:40

from a little layer in the rocks,

0:37:400:37:42

that was enriched in the element iridium.

0:37:420:37:44

And this was brought in and engendered by the arrival of this massive impact.

0:37:440:37:51

Although we talk about the dinosaurs dying out,

0:37:510:37:53

and they did, the ancestor of the birds was a small dinosaur.

0:37:530:37:58

-So the ancestor of the dodo was in fact a dinosaur?

-Exactly.

0:37:580:38:01

That's cruel irony for you, if you're a dodo in all this.

0:38:010:38:04

For all we know, one of those asteroids, meteorites,

0:38:040:38:07

comets, could be winging its way to us right now.

0:38:070:38:10

And there is no way we wouldn't have come up with a way of dealing with it, right? Course not.

0:38:100:38:13

Mark Steel has been to Berlin to meet the man with the plan.

0:38:130:38:16

The human race seems to love the idea of armageddon.

0:38:160:38:21

We are fascinated with the notion of being wiped out by ice ages

0:38:210:38:26

and alien invasions.

0:38:260:38:27

I had to keep a shovel by the front door for a year

0:38:270:38:30

because my son insisted it was the best way

0:38:300:38:32

of fighting off the inevitable zombie apocalypse.

0:38:320:38:36

But an impact between Earth and an asteroid does seem to be

0:38:360:38:42

the most credible of all these potential cataclysmic events.

0:38:420:38:45

So I have come to Berlin

0:38:490:38:51

to find out how we can avoid this death by asteroid.

0:38:510:38:54

I'm going to meet the leader of a multinational group

0:38:570:38:59

of scientists who hope to save us from impending armageddon.

0:38:590:39:03

'Professor Alan Harris is from the German Institute of Planetary Research.'

0:39:050:39:09

So, how do we detect these things, how do we come across them?

0:39:110:39:14

If you take a series of pictures like this

0:39:140:39:17

and track the object through

0:39:170:39:18

one night, and you come back the following night

0:39:180:39:22

and find it again, you can join the dots, as it were.

0:39:220:39:25

And that will tell you

0:39:250:39:26

if this asteroid is potentially hazardous or not.

0:39:260:39:29

In other words, could it one day hit the Earth?

0:39:290:39:32

So how likely is it that a dangerous extraterrestrial object

0:39:330:39:37

will hit Earth in, say, the next hundred years?

0:39:370:39:39

One that has been discovered is, I think, called Apophis,

0:39:420:39:45

-which is a near-Earth asteroid...

-Great names, by the way!

0:39:450:39:49

Is it people who were put out of work when Star Trek was finished,

0:39:490:39:54

and they had to come up with names?

0:39:540:39:56

Let me tell you that Apophis

0:39:560:39:58

will come very close to the Earth in the year 2029.

0:39:580:40:01

And it will pass by the Earth's surface at a distance

0:40:030:40:06

of about 30,000 kilometres.

0:40:060:40:08

Now, that is beneath the altitude of TV satellites, for instance.

0:40:100:40:15

So this is really coming into our back garden. It is a wake-up call.

0:40:150:40:19

But if it passes by the Earth at a particular distance

0:40:210:40:23

from a particular small region of space,

0:40:230:40:27

it could be deflected by the Earth's gravitational pull to exactly

0:40:270:40:31

the right extent that it might come back in 2036 and hit the Earth.

0:40:310:40:36

But the chances of this happening, I have to say,

0:40:400:40:43

are currently about one in 250,000, so don't lose sleep over it.

0:40:430:40:49

-Oh, right, it's better than winning the Lottery.

-Um, you're right!

0:40:490:40:53

'So apparently, there is a danger from space that could strike

0:40:570:41:01

'within our lifetimes. But if this is true,

0:41:010:41:03

'is there anything we can do about it?

0:41:030:41:06

'Well, this is where my new friend Alan comes in again.

0:41:100:41:13

'He is the project leader of the Near Earth Object Shield,

0:41:130:41:18

'or NEOShield for short.

0:41:180:41:20

'With a 5.8 million euro budget,

0:41:200:41:23

'they are investigating what methods could be used to avert armageddon,

0:41:230:41:26

'based on current technology.'

0:41:260:41:29

So, have you come up with

0:41:300:41:32

a favourite solution to the asteroid conundrum?

0:41:320:41:35

One is simply taking a massive spacecraft

0:41:350:41:39

and throwing it at the asteroid.

0:41:390:41:41

Here we have a very nasty, dangerous asteroid

0:41:430:41:46

that is on course for the Earth.

0:41:460:41:49

That blue ball there is the Earth.

0:41:490:41:52

And you are going to try

0:41:520:41:53

and deflect the asteroid with a kinetic impacter.

0:41:530:41:56

Try with this much lighter ball - that represents the spacecraft.

0:41:560:42:02

It didn't quite work,

0:42:040:42:05

and that is a very realistic scenario in which you could deflect

0:42:050:42:10

the asteroid slightly, but it could still end up hitting the Earth.

0:42:100:42:13

A different bit of the Earth.

0:42:130:42:14

Yes, and that is the problem,

0:42:140:42:16

because then you have a terrible political situation.

0:42:160:42:19

-It was about to hit Chicago, and you've deflected it to Peking.

-Yeah.

0:42:190:42:22

-Go on!

-Very good.

0:42:250:42:27

Another method we are considering in the NEOShield project

0:42:270:42:31

is something we call blast deflection.

0:42:310:42:32

And this is basically throwing a bomb at the asteroid.

0:42:320:42:37

This is going to be your bomb.

0:42:370:42:39

It is actually a blast of air, but it will do to try

0:42:390:42:42

and demonstrate the idea of blast deflection.

0:42:420:42:45

Oh, dear, it looks like you have failed.

0:42:480:42:50

I think we ought to try again.

0:42:500:42:51

We are going to try and make it more realistic by reducing

0:42:510:42:54

the size of the asteroid, making it much less massive than the Earth.

0:42:540:43:00

-That is, I think, the thing that stops it being realistic.

-Exactly.

0:43:000:43:03

Other than that, it's as if we're in space.

0:43:030:43:05

Ooh! You've just caught the outside of Turkey.

0:43:100:43:12

It skimmed through the atmosphere,

0:43:120:43:14

but you just saved millions of lives.

0:43:140:43:16

Hmm.

0:43:160:43:18

APPLAUSE

0:43:200:43:23

You all right, Mark? Let us hope that day never comes.

0:43:240:43:28

Were you impressed with the science of this?

0:43:280:43:30

Well, I don't know, I started out not particularly fretful,

0:43:300:43:35

to be honest, that we were going to be hit by an asteroid.

0:43:350:43:39

By the end of it, I thought, well, we're still not going to be

0:43:390:43:42

-hit by an asteroid, but if we are, then we're stuffed.

-Yeah, we are.

0:43:420:43:47

Apophis is the interesting one,

0:43:470:43:49

the one that is going to pass us in 2029.

0:43:490:43:53

Yes, well, there is one that is going to pass

0:43:530:43:56

and then possibly loop back, so that will be

0:43:560:43:59

an interesting eight-year period,

0:43:590:44:01

when we've just waited for an asteroid to come and destroy us.

0:44:010:44:05

I think we should point out, as has to be done intermittently

0:44:050:44:08

and repeatedly, the difference between the terms meteorite,

0:44:080:44:11

meteor, asteroid, comet...

0:44:110:44:12

It is quite hard, isn't it? I always forget.

0:44:120:44:14

Basically, anything which intrudes into our atmosphere from outer space

0:44:140:44:18

is an meteorite if it hits the ground

0:44:180:44:21

or a meteor if it is just a falling star?

0:44:210:44:23

So that can be either asteroid or comet. What is the difference between an asteroid and comet?

0:44:230:44:27

And asteroid is a rocky metal thing. It is really heavy.

0:44:270:44:31

This is a meteorite, but it could have come from an asteroid

0:44:310:44:35

and burnt up and hit the ground.

0:44:350:44:37

This hit the ground in Arizona in 1891.

0:44:370:44:40

It is really worth holding in your hand because it is enormously heavy.

0:44:400:44:46

The main thing of holding it in your hand is that this has been in space!

0:44:460:44:51

-It feeds the six-year-old in you.

-It does.

0:44:510:44:54

Although it really would damage the six-year-old in you

0:44:540:44:58

if you happen to be standing underneath it when it hit.

0:44:580:45:01

We have comets here. This is our favourite, Halley's Comet.

0:45:010:45:03

We sent Giotto up to have a look. We have the photographs.

0:45:030:45:06

You are going to make a comet for us.

0:45:060:45:09

To get your head round what a comet is... The best way is to make one.

0:45:090:45:13

Here we go. We're going to make a comet

0:45:130:45:15

The early European space mission Giotto to Halley's Comet

0:45:150:45:21

discovered something great about them which is that they have a lot of water in them.

0:45:210:45:24

First of all, we will mix up some water. Also carbon.

0:45:240:45:28

That is a common element in the solar system and there is loads.

0:45:280:45:33

We have the image of a dirty snowball.

0:45:330:45:37

These things are icy, but they don't look like a snowball.

0:45:370:45:41

There is some mineral content - silica, aluminium and a few other things.

0:45:410:45:45

Which you are representing with sand here.

0:45:450:45:48

The incredible thing is that the NASA Stardust mission, to Wild 2,

0:45:480:45:52

they found they had amino acids in them.

0:45:520:45:55

That was really startling and amazing

0:45:550:45:57

-cos that means....

-We got these from bodybuilders.

0:45:570:46:01

It's incredible because that might suggest that comets cannot just be

0:46:010:46:06

harbingers of doom, but they carry the components of life.

0:46:060:46:10

Amino acids are the building blocks of all our protein.

0:46:100:46:12

Is there any justification for using Eastern European vodka?

0:46:120:46:17

It's not vodka. It's ethanol, alcohol.

0:46:170:46:21

Not only did these comets deliver water, but booze.

0:46:210:46:27

So there is volatiles, there is organics in there,

0:46:270:46:29

and of course, there is carbon dioxide.

0:46:290:46:32

I wonder if you can help me. Mark, can you put on these gloves?

0:46:320:46:35

We should all put on gloves and safety glasses.

0:46:350:46:38

Although this is solid carbon dioxide, it is -78C.

0:46:380:46:43

It's not terribly dangerous, but it will give you frostbite.

0:46:430:46:46

What we do next means that it might spit.

0:46:460:46:51

Whack that in here.

0:46:510:46:54

-How much of this goes in there?

-About three cups.

0:46:540:46:58

That will cool this down and create this icy black snowball.

0:46:580:47:02

-Cheap special effects.

-This is brilliant.

0:47:020:47:05

-I shouldn't put my hand in there.

-Don't put your hand in.

0:47:050:47:09

If a comet landed, all the rock bands in the world would have

0:47:090:47:12

to rush out really quickly.

0:47:120:47:16

This looks like some cheap trick.

0:47:160:47:20

But it will create something that is uncannily like a comet.

0:47:200:47:25

I'm trying to solidify that water we put in there

0:47:250:47:30

and all the carbon and the vodka is being squeezed together.

0:47:300:47:36

I think we have a comet. OK.

0:47:360:47:39

If you have just tuned in,

0:47:390:47:41

this isn't the Great British Bake Off.

0:47:410:47:44

-Look.

-Oh, wow!

0:47:440:47:47

Look at the jets. The jets coming across.

0:47:470:47:49

These are the carbon dioxide subliming and creating...

0:47:490:47:54

And cooling the water and the water in the air is creating this steam.

0:47:540:47:59

There would be jets on an actual comet?

0:47:590:48:02

As it comes near the sun, this starts to happen.

0:48:020:48:05

As it comes near to Mark, the warmth of his charisma,

0:48:050:48:08

his personality starts to warm the side of it.

0:48:080:48:11

And that is the coma you see around a comet.

0:48:110:48:14

It's amazing how much you've created a comet

0:48:140:48:18

-that looks like a human brain.

-Yeah.

0:48:180:48:21

Wow, that's fantastic. That's exactly as it would appear in space.

0:48:210:48:25

Ladies and gentlemen, this is Mark Miodownik's comet.

0:48:250:48:29

APPLAUSE

0:48:290:48:31

If tonight's programme has given you

0:48:310:48:33

some burning questions about extinction,

0:48:330:48:35

we have our after-hours science club starting when we finish.

0:48:350:48:38

Go to the website and get involved.

0:48:380:48:40

APPLAUSE

0:48:400:48:43

Loads more sources of information for you there.

0:48:430:48:47

Now we have our unsung scientist Hall of Fame.

0:48:470:48:50

This is where we big up scientists

0:48:500:48:52

who don't get enough credit for their achievements.

0:48:520:48:54

Richard, who would you like to add to the Hall of Fame?

0:48:540:48:57

We have heard about the influence of guns on life.

0:48:570:49:02

One wonderful species that almost died out,

0:49:020:49:06

almost became extinct, was the North American buffalo, the bison.

0:49:060:49:11

It was only thanks to a few people who conserved them,

0:49:110:49:15

who valued then, that this species survives now.

0:49:150:49:18

My unsung hero is a farmer or farmer's wife, Molly Goodnight...

0:49:180:49:24

who kept a small herd

0:49:240:49:28

and now there are healthy populations once again

0:49:280:49:31

of this magnificent animal.

0:49:310:49:33

Who are you going to add?

0:49:330:49:34

Alfred Russel Wallace who discovered my favourite frog

0:49:340:49:39

which is... LAUGHTER

0:49:390:49:41

You're noticing a theme here.

0:49:410:49:43

He discovered Wallace's flying frog which is a frog that flies

0:49:430:49:47

which is amazing. But that's not why he's going on.

0:49:470:49:50

He's going on because he thought of the theory of evolution

0:49:500:49:53

by natural selection,

0:49:530:49:54

possibly even before Darwin or definitely around the same time.

0:49:540:49:59

The co-presented. You never hear about Arthur Russell Wallace.

0:49:590:50:02

You always hear about Charles Darwin.

0:50:020:50:04

Do you want to take Darwin out of the...?

0:50:040:50:06

-And put Alfred Russel Wallace in.

-That's not going down well in the room.

0:50:060:50:10

Genuinely spontaneous booing for that.

0:50:100:50:12

The one I'm going to bring in is our old friend Lancelot Hogben

0:50:120:50:18

who invented the frog-based pregnancy test that you'll be delighted to know

0:50:180:50:23

isn't the way you'll be pacing

0:50:230:50:25

nervously in a bathroom in 10 years' time.

0:50:250:50:27

-He was the one who popularised that frog?

-Absolutely.

0:50:270:50:31

It was because he turned it into a scientific superstar.

0:50:310:50:35

That's the reason it became a model organism. He has a lot to answer for.

0:50:350:50:40

He goes on to the side. Thank you very much.

0:50:400:50:44

I told you at the start of the show this wouldn't be a big depressing

0:50:440:50:47

guilt trip about how bad we are to little animals and pandas crying.

0:50:470:50:52

Yes, resources and species are disappearing at an alarming rate and

0:50:520:50:55

it may be all our fault, but we, as humans, have ingenuity on our side.

0:50:550:50:59

What if we could bring these defunct species back?

0:50:590:51:03

Dr Helen Czerski has been to New Orleans

0:51:030:51:05

to uncover some astonishing experiments.

0:51:050:51:08

Keeping endangered animals behind bars is one way to preserve them

0:51:110:51:15

for future generations.

0:51:150:51:18

The idea of rescuing a few specimens in the hope that they'll breed

0:51:180:51:22

is as old as Noah's Ark.

0:51:220:51:25

Creating Noah's Ark in a zoo isn't practical because, even if

0:51:250:51:29

you had several of every species,

0:51:290:51:32

you have then the enormous problem of finding habitats and food for them.

0:51:320:51:37

At the Audubon Nature Institute in New Orleans, they have a solution.

0:51:370:51:42

A way of keeping animals that doesn't have those problems.

0:51:420:51:46

They're building a genetic ark.

0:51:460:51:48

For over 10 years, Martha Gomez and her team have been collecting

0:51:530:51:57

the next generation of endangered animals

0:51:570:51:59

by storing their DNA in liquid nitrogen.

0:51:590:52:03

Basically, we have here the frozen soup.

0:52:030:52:07

We have cells from lions, antelopes, gorilla and elephants.

0:52:070:52:13

What Martha's team have is effectively a biological hard drive

0:52:150:52:18

to recreate endangered species from around the world.

0:52:180:52:23

After defrosting genetic material like these wildcats sperm and eggs,

0:52:230:52:28

they use IVF procedures to create new embryos in the lab.

0:52:280:52:33

These eggs, there is a cell membrane round the outside

0:52:330:52:38

-and the genetic material from the mother is in there.

-Exactly.

0:52:380:52:42

Then swimming around out here,

0:52:420:52:45

these are all the sperm with the genetic material from the father.

0:52:450:52:48

-Mm-hmm.

-They are combining here.

-It is in-vitro fertilisation.

0:52:480:52:54

-Is this better magnification?

-Yes.

-Look at that!

0:52:540:52:58

You can see how many sperm you have around. And just one...

0:52:580:53:03

-One more cat in the world, here we go.

-Here we go.

0:53:030:53:08

By freezing the embryos, too,

0:53:090:53:12

Martha's team are experimenting with starting life

0:53:120:53:16

then pausing it at will.

0:53:160:53:18

Defrosting the embryos of endangered species years down the line is

0:53:190:53:23

all very well, but they need mothers to bring them into the world.

0:53:230:53:26

So what do you do if the mothers are dying out?

0:53:260:53:31

This African black-footed wildcat is the first of her kind to be

0:53:310:53:35

born through interspecies surrogacy.

0:53:350:53:39

This is Crystal.

0:53:400:53:41

She might be the most astonishing animal I have ever seen.

0:53:410:53:46

The sperm that make up half of her DNA were frozen for a year

0:53:460:53:51

then they joined the egg to make an embryo

0:53:510:53:55

and that embryo was frozen for eight more years.

0:53:550:54:00

And at the end of that,

0:54:000:54:02

that embryo was implanted not in the same species as Crystal,

0:54:020:54:07

but in a domestic cat.

0:54:070:54:11

So that little cat over there was carried to term

0:54:110:54:15

by a mother of a whole separate species.

0:54:150:54:20

So, even if an animal becomes extinct,

0:54:230:54:26

the frozen zoo could use a common relative to resurrect the species.

0:54:260:54:30

But in their latest research,

0:54:320:54:33

Martha's team don't even need frozen sperm and eggs.

0:54:330:54:37

They can now create an embryo from a skin cell using cloning.

0:54:380:54:42

A normal domestic cat donates unfertilised eggs or oocytes.

0:54:440:54:49

Under the microscope, Martha adds fluorescent dye to make

0:54:510:54:55

the mother's DNA visible for extraction from the oocyte.

0:54:550:54:58

What she's doing is going in with another pipette

0:54:580:55:01

and removing the DNA that is already in this egg cell.

0:55:010:55:05

The DNA is now here and there is nothing...

0:55:050:55:09

Nothing. Can you see that this is the DNA?

0:55:090:55:12

Now that there is an empty egg cell,

0:55:150:55:18

a blank, the next stage is to take one of these cells that has come from

0:55:180:55:22

the skin tissue of a different species of cat

0:55:220:55:25

and put that into the oocyte.

0:55:250:55:28

That's the complete genetic package effectively going into the egg cell.

0:55:280:55:33

So the domestic cat DNA inside the egg

0:55:350:55:38

has been replaced with wildcat DNA.

0:55:380:55:41

Martha will apply an electric pulse across the cell

0:55:440:55:48

so that the new DNA will fuse with the egg cell.

0:55:480:55:53

This is the spark of life.

0:55:530:55:56

I'm going to pass it. 3, 2, 1.

0:55:560:55:59

What I do there is helping.

0:56:040:56:06

You can clearly see how the cell got attached.

0:56:060:56:09

Cloning is nothing new, but using separate species to provide eggs

0:56:110:56:14

and surrogate mothers is groundbreaking.

0:56:140:56:16

Martha's team hope to eventually clone tigers

0:56:180:56:23

using the more common lion as a surrogate.

0:56:230:56:26

This technology opens up tantalising possibilities for long extinct animals.

0:56:260:56:30

APPLAUSE

0:56:300:56:32

That is astonishing. It's nothing short of miraculous.

0:56:390:56:42

Even watching the video again, shivers are going down my spine.

0:56:420:56:46

We spent two days there and they have honed this procedure.

0:56:460:56:49

It's very clever. They're using the natural machinery of the cells.

0:56:490:56:53

So there is little artificial about it.

0:56:530:56:55

They are switching things in the cell the right way,

0:56:550:56:59

so they can put whole skin cells into this egg.

0:56:590:57:02

-The technology is astonishing. It makes me shiver.

-Dinosaurs?

0:57:020:57:07

Is that a stupid question? This is Jurassic Park.

0:57:070:57:11

It's all about the integrity of the DNA.

0:57:110:57:13

To reproduce an entire animal,

0:57:130:57:15

you need a lot of things to be exactly right.

0:57:150:57:18

In the depths of mammoth DNA that have been found so far,

0:57:180:57:21

no-one's got an intact sequence.

0:57:210:57:23

It's difficult to patch together sequences from different animals.

0:57:230:57:27

DNA does denature quite quickly.

0:57:270:57:31

No DNA has survived in any decent chunks from the age of the dinosaurs.

0:57:310:57:36

The mammoth is a more interesting possibility,

0:57:360:57:39

because deep frozen mammoths are found...

0:57:390:57:41

Wrangel Island, they lived until just a few thousand years ago.

0:57:410:57:45

It's just conceivable that somewhere, there would be a whole strand.

0:57:450:57:51

That is the passenger pigeon shot by a 14-year-old in Ohio

0:57:510:57:56

in the year 1900. Presumably, whose great-grandchildren are still alive.

0:57:560:58:00

So, if you could bring him back he could fly above and shit on him.

0:58:000:58:04

That would be a small piece of vengeance.

0:58:040:58:07

It's a miraculous film but it may be a far more confusing

0:58:070:58:10

and complex issue than that.

0:58:100:58:12

We are almost at the end. Mark, if you could come back in again.

0:58:120:58:15

We want to thank all our reporters. Helen, Tali, Alok and of course our own Mark.

0:58:180:58:21

Mainly our science gurus Richard Fortey

0:58:210:58:23

Lucy Cooke and of course our special guest Mark steel.

0:58:230:58:26

How do we tie a bow on this, ladies and gentlemen?

0:58:340:58:36

Given what we've done to the animals, we've shot them,

0:58:360:58:39

eaten them, knocked down their homes, introduced them to cats

0:58:390:58:42

and we've weed on them to find out if we're pregnant.

0:58:420:58:45

We probably deserve an asteroid strike, but before that happens,

0:58:450:58:48

we're coming after the pandas.

0:58:480:58:50

Ladies and gentlemen, that's all for this week. Good night.

0:58:500:58:53

APPLAUSE

0:58:530:58:55

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0:59:070:59:09

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