Science monkey superhero Dr Brain pits children and CBBC celebrities against one another in a series of science-based tasks and conundrums designed to discover the 'ultimate brain'.
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Stars of MOTD Kickabout take on two young teams in a mash-up of science and entertainment.
Matilda Ramsay and her twin siblings take on two young teams.
The stars of 4 O'Clock Club take on two young teams.
The Wolfblood actors who play the Three Ks challenge teams of children.
Actors from The Next Step, Millie Inbetween and Hetty Feather take on two teams of girls.
CBBC HQ stars Katie Thistleton, Karim Zeroual and Lauren Layfield take on two young teams.
Technobabble's Frankie Vu and Marcus Bronzy, as well as Harvey Cantwell take on two teams.
Johnny and Inel and Britain's Got Talent's Ashleigh and Pudsey take on two young teams.
Actors from So Awkward take on two young teams in a mash-up of science and entertainment.
Laura from Whoops I Missed the Bus and the Mandeville Sisters take on two young teams.